|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Impact of disease severity on gastric residual volume in critical patients显示文摘AIM: To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS: Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of the study. Acute Physiology and Chronic Health Evaluation (APACHE) Ⅱ scores were recorded on the first, fourth, seventh, and fourteenth day of the study period. GRV was measured every 4 h during enteral feeding. The relationship be-tween mean daily GRV and SOFA scores and the correlation between mean daily GRV and mean APACHE Ⅱ score of all patients were evaluated and compared. RESULTS: Of the 61 patients, 43 patients were survivors and 18 patients were non-survivors. The mean daily GRV increased as SOFA scores increased (P < 0.001, analysis of variance). Mean APACHE Ⅱ scores of all patients correlated with mean daily GRV (P = 0.011, Pearson correlation) during the study period. Patients with decreasing GRV in the first 2 d had better survival than patients without decreasing GRV (P = 0.017, log rank test). CONCLUSION: GRV is higher in more severely ill medical ICU patients. Patients with decreasing GRV had lower ICU mortality than patients without decreasing GRV. | Chien-Wei Hsu Shu-Fen Sun David Lin Lee Shoa-Lin Lin Kam-Fai Wong Hsiu-Hua Huang Hung-Ju Li | 2011 | World Journal of Gastroenterology2011，17，15： | 8 |
| 2 | Hybrid therapy for Helicobacter pylori infection:A systemic review and meta-analysis显示文摘AIM: To compare the effectiveness of hybrid therapy with other recommended regimens using metaanalysis.METHODS: Bibliographical searches for randomized trials comparing hybrid and other therapies were performed in Pubmed, the Cochrane Library and relevant congresses up to February 2015 using the following keywords(all fields and/or me SH):('Helicobacter pylori ' or 'H. pylori') and('hybrid therapy' or 'sequential-concomitant therapy'). metaanalyses were performed with Cochrane Review manager 5.1. The random effect model proposed by Der Simonian and Laird and the mantel-Haenszel method were used to estimate the pooled relative risk and 95%CI of the efficacy outcomes between hybrid therapy and other eradication therapies. RESULTS: Eight studies(2516 subjects) met entry criteria. The antimicrobial resistance in the study groups ranged from 6.9% to 23.5%. The mean cure rates of hybrid therapy by intention-to-treat(ITT) and perprotocol analyses were 88.5%(n = 1207; range: 80.0% to 97.4%) and 93.3%(n = 1109; range: 85.7% to99.1%), respectively. meta-analysis showed there was no significant difference in ITT eradication rate between hybrid and sequential therapy(relative risk: 1.01; 95%CI: 0.92-1.11). Subgroup analysis revealed hybrid therapy was more effective than sequential therapy in the non-Italian populations(95%CI: 1.01-1.18) and was only less effective in one, Italian population(95%CI: 0.83-0.98). There was no significant difference in eradication rate between hybrid therapy and concomitant therapy(95%CI: 0.93-1.02). No head-tohead comparisons of hybrid therapy and standard triple therapy or bismuth quadruple therapy were found. However, a multicenter, randomized trial showed that reverse hybrid therapy was superior to standard triple therapy(95.5% vs 88.6% ITT; P = 0.011).CONCLUSION: Hybrid therapy appears to be an effective, safe, and well-tolerated treatment for H. pylori infection in the era of increasing antibiotic resistance. | Ping-I Hsu Pei-Chin Lin David Y Graham | 2015 | World Journal of Gastroenterology2015，21，45： | 8 |
| 3 | Sequential and Concomitant Therapy With Four Drugs Is Equally Effective for Eradication of H pylori Infection显示文摘 | Deng–Chyang Wu Ping–I. Hsu Jeng–Yih Wu Antone R. Opekun Chao–Hung Kuo I.–Chen Wu Sophie S.W. Wang Angela Chen Wen–Chun Hung David Y. Graham | 2010 | Clinical Gastroenterology and Hepatology2010，，1： | 7 |
| 4 | Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity显示文摘 | F. Ann Ran Patrick D. Hsu Chie-Yu Lin Jonathan S. Gootenberg Silvana Konermann Alexandro E. Trevino David A. Scott Azusa Inoue Shogo Matoba Yi Zhang Feng Zhang | 2013 | Cell2013，，2： | 4 |
| 5 | Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification显示文摘Heterotopic ossification(HO)is a debilitating condition characterized by the pathologic formation of ectopic bone.HO occurs commonly following orthopedic surgeries,burns,and neurologic injuries.While surgical excision may provide palliation,the procedure is often burdened with significant intra-operative blood loss due to a more robust contribution of blood supply to the pathologic bone than to native bone.Based on these clinical observations,we set out to examine the role of vascular signaling in HO.Vascular endothelial growth factor A(VEGFA)has previously been shown to be a crucial pro-angiogenic and pro-osteogenic cue during normal bone development and homeostasis.Our findings,using a validated mouse model of HO,demonstrate that HO lesions are highly vascular,and that VEGFA is critical to ectopic bone formation,despite lacking a contribution of endothelial cells within the developing anlagen. | Charles Hwang Simone Marini Amanda KHuber David MStepien Michael Sorkin Shawn Loder Chase APagani John Li Noelle DVisser Kaetlin Vasquez Mohamed AGarada Shuli Li Jiajia Xu Ching-Yun Hsu Paul BYu Aaron WJames Yuji Mishina Shailesh Agarwal Jun Li Benjamin Levi | 2019 | Bone Research2019，7，4： | 4 |
| 6 | Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB显示文摘 | Dos D. Sarbassov Siraj M. Ali Shomit Sengupta Joon-Ho Sheen Peggy P. Hsu Alex F. Bagley Andrew L. Markhard David M. Sabatini | 2006 | Molecular Cell2006，，2： | 2 |
| 7 | Meta-analysis of new genome-wide association studies of colorectal cancer risk显示文摘 | Ulrike Peters Carolyn M. Hutter Li Hsu Fredrick R. Schumacher David V. Conti Christopher S. Carlson Christopher K. Edlund Robert W. Haile Steven Gallinger Brent W. Zanke Mathieu Lemire Jagadish Rangrej Raakhee Vijayaraghavan Andrew T. Chan Aditi Hazra Dav | 2012 | Human Genetics2012，，2： | 2 |
| 8 | 超声成像法检测复合材料层合板铺层方向显示文摘提出一种确定复合材料层合板铺设形式的新的无损检测方法。采用垂直入射的超声纵波进行铺层界面的C扫描或层板全波形B扫描,然后从结构缺陷的反射波中提取纤维方向信息。发现铺层界面的C扫描图大都包含两相邻铺层的纤维方向信息,而上铺层的信息显示更明显。因此,用二维傅里叶变换将界面C扫描图变换为定量的角度分布图,通过显示的方向信息确定上铺层的纤维方向。用类似方法对全波形B扫描图进行处理,将其转换为角度 时间图,图中信号幅度显示层合板中各铺层的方向。由于没有涉及众多界面时间门的设置问题,B扫描方法更为简单。分别用界面C扫描和全波形B扫描方法检测了几种复合材料层合板,确定了它们的铺制结构,并通过建模分析研究这些方法的机理。 | David K HSU 费冬 刘战捷 | 2004 | 无损检测2004，26，1： | 2 |
| 9 | Feasibility of Shortening 14‐day Hybrid Therapy While Maintaining an Excellent Helicobacter pylori Eradication Rate显示文摘 | Jeng‐Yih Wu Ping‐I Hsu Deng‐Chyang Wu David Y. Graham Wen‐Ming Wang | 2014 | Helicobacter2014，，3： | 2 |
| 10 | Sequential and Concomitant Therapy With Four Drugs Is Equally Effective for Eradication of H pylori Infection显示文摘 | Deng–Chyang Wu Ping–I. Hsu Jeng–Yih Wu Antone R. Opekun Chao–Hung Kuo I.–Chen Wu Sophie S.W. Wang Angela Chen Wen–Chun Hung David Y. Graham | 2010 | Clinical Gastroenterology and Hepatology2010，，1： | 2 |
| 11 | Capsule Endoscopy in Patients with Implantable Electromedical Devices is Safe显示文摘 | Lucinda A. Harris Stephanie L. Hansel Elizabeth Rajan Komandoor Srivathsan Robert Rea Michael D. Crowell David E. Fleischer Shabana F. Pasha Suryakanth R. Gurudu Russell I. Heigh Arthur D. Shiff Janice K. Post Jonathan A. Leighton Hsu Heng Yen | 2013 | Gastroenterology Research and Practice2013，，： | 2 |
| 12 | Cancer Cell Metabolism: Warburg and Beyond显示文摘 | Peggy P. Hsu David M. Sabatini | 2008 | Cell2008，，5： | 2 |
| 13 | Experienced entrepreneurial founders, organizational capital, and venture capital funding显示文摘 | David H. Hsu | 2007 | Research Policy2007，，5： | 1 |
| 14 | An information-centric energy infrastructure: The Berkeley view显示文摘 | Randy H. Katz David E. Culler Seth Sanders Sara Alspaugh Yanpei Chen Stephen Dawson-Haggerty Prabal Dutta Mike He Xiaofan Jiang Laura Keys Andrew Krioukov Ken Lutz Jorge Ortiz Prashanth Mohan Evan Reutzel Jay Taneja Jeff Hsu Sushant Shankar | 2010 | Sustainable Computing: Informatics and Systems2010，，1： | 1 |
| 15 | The TNF receptor 1-associated prorein TRADD signals cell death and NF-B activation显示文摘 | Hsu H Xiong J David V | 1995 | Cell1995，81，： | 1 |
| 16 | Impact of Lactobacillus reuteri Supplementation on Anti- Helicobacter pylori Levofloxacin-Based Second-Line Therapy显示文摘 | Veronica Ojetti Giovanni Bruno Maria Elena Ainora Giovanni Gigante Gianluca Rizzo Davide Roccarina Antonio Gasbarrini Ping-I Hsu | 2012 | Gastroenterology Research and Practice2012，，： | 1 |
| 17 | Propofo exerts protective effects on the acute lung injury in duced by endotoxin in rats显示文摘 | Chu CH David Liu D Hsu YH | 2007 | Pulm Pharmacol T her2007，20，5： | 1 |
| 18 | TNF-Dependent Recruitment of the Protein Kinase RIP to the TNF Receptor-1 Signaling Complex显示文摘 | Hailing Hsu Jianing Huang Hong-Bing Shu Vijay Baichwal David V Goeddel | 1996 | Immunity1996，，： | 1 |
| 19 | Propofol exerts protective effects on the acute lung injury induced by endotoxin in rats 显示文摘 | Chu CH David Liu D Hsu YH | 2007 | Pulm Pharmacol Ther2007，20，5： | 1 |
| 20 | Toll-Like Receptor-4 Promotes the Development of Colitis-Associated Colorectal Tumors显示文摘 | Masayuki Fukata Anli Chen Arunan S. Vamadevan Jason Cohen Keith Breglio Suneeta Krishnareddy David Hsu Ruliang Xu Noam Harpaz Andrew J. Dannenberg Kotha Subbaramaiah Harry S. Cooper Steven H. Itzkowitz Maria T. Abreu | 2007 | Gastroenterology2007，，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员