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| 1 | Ovarian tumor-associated microRNA-20a decreases natural killer cell cytotoxicity by downregulating MICA/B expression显示文摘MicroRNAs (miRNAs ) 是小非编码的规章的 RNA 的一个班,并且在 miRNAs 的变化涉及肿瘤起源和前进。研究证明了 miR-20a 是在人的卵巢的癌症纸巾的 overexpressed 并且这 miRNA 提高长期的细胞的增长和侵略能力。在这研究,在浆液 miR-20a 表示和卵巢的癌症舞台之间的积极关联被观察。我们发现 miR-20a 直接绑,导致它的降级并且减少它 MICA/B mRNA 的 -untranslated 区域在血浆膜上铺平的蛋白质 3 ′。膜界限 MICA/B 蛋白质的减小,是 2 成员 D (NKG2D ) 受体在生来的杀手(NK ) 上发现了房间的生来的迷人的组的 ligands, γ δ + T 房间和 CD8 + T 房间,允许肿瘤房间躲避调停免疫者的杀死。尤其是,反对 miR-20a 行动提高了在 vitro 并且在肿瘤的 vivo 模型的在两个的肿瘤房间的调停 NKG2D 的杀死。一起拿,我们的数据显示在肿瘤房间的 miR-20a 的增加的层次可以间接地由 downregulating MICA/B 压制 NK 房间 cytotoxicity 表达式。这些数据提供在转移能力和 NK 房间的肿瘤房间的有免疫力的逃跑之间的一个潜在的连接。 | Jingyan Xie Mengna Liu Yujuan Li Yunzhong Nie Qiongyu Mi Shuli Zhao | 2014 | Cellular & Molecular Immunology2014，11，5： | 10 |
| 2 | Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets显示文摘Background: Evidence indicates that early weaning predisposes piglets to intestinal oxidative stress and increases the risk of intestinal dysfunction;however, there are minimal satisfactory treatment strategies for these conditions.This study investigated the potential of resveratrol and its analog, pterostilbene, as antioxidant protectants for regulating intestinal morphology, barrier function, and redox status among weanling piglets.Methods: A total of 144 piglets were selected at 21 days of age and randomly allocated into one of four treatment groups, each of which included six replicates. Piglets in a sow-reared control group were suckling normally between ages 21 and 28 days, while those in weaned groups were fed a basal diet, supplemented with either 300 mg/kg of resveratrol or with 300 mg/kg of pterostilbene. Parameters associated with intestinal injury and redox status were analyzed at the end of the feeding trial.Results: Early weaning disrupted the intestinal function of young piglets, with evidence of increased diamine oxidase activity and D-lactate content in the plasma, shorter villi, an imbalance between cell proliferation and apoptosis, an impaired antioxidant defense system, and severe oxidative damage in the jejunum relative to suckling piglets. Feeding piglets with a resveratrol-supplemented diet partially increased villus height(P = 0.056) and tended to diminish apoptotic cell numbers(P = 0.084) in the jejunum compared with those fed a basal diet. Similarly, these beneficial effects were observed in the pterostilbene-fed piglets. Pterostilbene improved the feed efficiency of weanling piglets between the ages of 21 and 28 days;it also resulted in diminished plasma diamine oxidase activity and D-lactate content relative to untreated weaned piglets(P < 0.05). Notably, pterostilbene restored jejunal antioxidant capacity, an effect that was nearly absent in the resveratrol-fed piglets. Pterostilbene reduced the malondialdehyde and 8-hydroxy-2′-deoxyguanosine contents of jejunal mucosa possibly through its regulatory role in facilitating the nuclear translocation of nuclear factor erythroid-2-related factor 2 and the expression levels of NAD(P)H quinone dehydrogenase 1 and superoxide dismutase 2(P < 0.05).Conclusions: The results indicate that pterostilbene may be more effective than its parent compound in alleviating early weaning-induced intestinal damage and redox imbalance among young piglets. | Hao Zhang Yanan Chen Yueping Chen Shuli Ji Peilu Jia Yue Li Tian Wang | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 8 |
| 3 | Facile synthesis of graphene via reduction of graphene oxide by artemisinin in ethanol显示文摘The preparation of reduced graphene oxide(RGO)by chemical reduction of graphene oxide(GO)usually involves highly toxic reducing agents which are harmful to the environment and human health.In this paper,a mediated facile and relative green approach for the preparation of RGO in ethanol using artemisinin as a reducing agent is reported for the first time.The morphology and de-oxidation efficiency of the obtained RGO were characterized by transmission electron microscope(TEM),atomic force microscope(AFM),and X-ray photoelectron spectroscopy(XPS).The results showed that artemisinin can effectively reduce GO into few-layered RGO with a high carbon to oxygen ratio(11.7).The mechanism for elimination of oxygen-containing functional groups decorated on GO nanosheets by artemisinin was proposed.The important features of relatively environmentally friendly and facile operation procedures endow this approach with great promise in the mass production of RGO and various graphene-based materials,especially for biomaterials. | Dandan Hou Qinfu Liu Xianshuai Wang Ying Quan Zhichuan Qiao Li Yu Shuli Ding | 2018 | Journal of Materiomics2018，4，3： | 6 |
| 4 | Expert consensus on early childhood caries management显示文摘Early childhood caries(ECC)is a significant chronic disease of childhood and a rising public health burden worldwide.ECC may cause a higher risk of new caries lesions in both primary and permanent dentition,affecting lifelong oral health.The occurrence of ECC has been closely related to the core microbiome change in the oral cavity,which may be influenced by diet habits,oral health management,fluoride use,and dental manipulations.So,it is essential to improve parental oral health and awareness of health care,to establish a dental home at the early stage of childhood,and make an individualized caries management plan.Dental interventions according to the minimally invasive concept should be carried out to treat dental caries.This expert consensus mainly discusses the etiology of ECC,caries-risk assessment of children,prevention and treatment plan of ECC,aiming to achieve lifelong oral health. | Jing Zou Qin Du Lihong Ge Jun Wang Xiaojing Wang Yuqing Li Guangtai Song Wei Zhao Xu Chen Beizhan Jiang Yufeng Mei Yang Huang Shuli Deng Hongmei Zhang Yanhong Li Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，3： | 5 |
| 5 | Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification显示文摘Heterotopic ossification(HO)is a debilitating condition characterized by the pathologic formation of ectopic bone.HO occurs commonly following orthopedic surgeries,burns,and neurologic injuries.While surgical excision may provide palliation,the procedure is often burdened with significant intra-operative blood loss due to a more robust contribution of blood supply to the pathologic bone than to native bone.Based on these clinical observations,we set out to examine the role of vascular signaling in HO.Vascular endothelial growth factor A(VEGFA)has previously been shown to be a crucial pro-angiogenic and pro-osteogenic cue during normal bone development and homeostasis.Our findings,using a validated mouse model of HO,demonstrate that HO lesions are highly vascular,and that VEGFA is critical to ectopic bone formation,despite lacking a contribution of endothelial cells within the developing anlagen. | Charles Hwang Simone Marini Amanda KHuber David MStepien Michael Sorkin Shawn Loder Chase APagani John Li Noelle DVisser Kaetlin Vasquez Mohamed AGarada Shuli Li Jiajia Xu Ching-Yun Hsu Paul BYu Aaron WJames Yuji Mishina Shailesh Agarwal Jun Li Benjamin Levi | 2019 | Bone Research2019，7，4： | 4 |
| 6 | Multi-sensor image registration by combining local self-similarity matching and mutual information显示文摘Automatic multi-sensor image registration is a challenging task in remote sensing.Conventional image registration algorithms may not be applicable when common underlying visual features are not distinct.In this paper,we propose a novel image registration approach that integrates local self-similarity (LSS)and mutual information (MI)for multi-sensor images with rigid/non- rigid radiometric and geometric distortions.LSS is a well- performing descriptor that captures common,local internal layout features for multi-sensor images,whereas MI focuses on global intensity relationships.First,potential control points are identified by using the Harris algorithm and screened based on the self-similarity of their local surrounding internal layouts.Second,a Bayesian prob- abilistic model for matching the ensemble of the LSS features is introduced.Third,a particle swarm optimization (PSO)algorithm is adopted to optimize the point and region correspondences for maximum self-similarity and MI and,ultimately,a robust mapping function.The proposed approach is compared with several conventional image registration algorithms that are based on the sum of squared differences (SSD),scale-invariant feature trans- forms (SIFT),and speeded-up robust features (SURF) through the experimental registration of pairs of Landsat TM,SPOT,and RADARSAT SAR images.The results demonstrate that the proposed approach is efficient and accurate. | Xiaoping LIU Shuli CHEN Li ZHUO Jun LI Kangning HUANG | 2018 | Frontiers of Earth Science2018，12，4： | 4 |
| 7 | Different responses of soil respiration and its components to nitrogen and phosphorus addition in a subtropical secondary forest显示文摘Background:Nitrogen(N)and phosphorus(P)deposition have largely affected soil respiration(Rs)in forest ecosystems.However,few studies have explored how N and P individually or in combination to influence Rs and its components(autotrophic respiration,Ra;heterotrophic respiration,Rh),especially in highly P-limited subtropical forests.To address this question,we conducted a field manipulation experiment with N and/or P addition in a 50-year-old subtropical secondary forest.Results:We found that N addition on average reduced Rs,Ra,and Rh by 15.2%,15%,and 11.7%,respectively during 2-year field study.P addition had an inconsistent effect on Ra,with Ra increasing by 50.5%in the first year but reducing by 26.6%in the second year.Moreover,P addition on average decreased Rh by 8.9%–30.9%and Rs by 6.7%–15.6%across 2 years.In contrast,N and P co-addition on average increased Rs,Ra,and Rh by 1.9%,7.9%,and 2.1%during the experimental period.Though Rs and Rh were significantly correlated with soil temperature,their temperature sensitivities were not significantly changed by fertilization.Ra was predominantly regulated by soil nitrogen availability(NH4+and NO3−),soil dissolved organic carbon(DOC),and enzyme activities,while the variation in Rh was mainly attributable to changes in soil microbial community composition and soilβ-D-Cellubiosidase(CB)andβ-Xylosidase(XYL)activities.Conclusion:Our findings highlight the contrasting responses of Rs and its components to N or P addition against N and P co-addition,which should be differentially considered in biogeochemical models in order to improve prediction of forest carbon dynamics in the context of N and P enrichment in terrestrial ecosystems. | Junjun Zhang Yong Li Jinsong Wang Weinan Chen Dashuan Tian Shuli Niu | 2021 | Forest Ecosystems2021，8，3： | 3 |
| 8 | Experimental Study on Refinery Gas Desulfurization Using Gas-Liquid Membrane Contactor显示文摘与 polytetrafluoroethylene ( PTFE )或聚丙烯( PP )装备的煤气液体的电流接触器恐水病的膜被申请从精炼厂 gas.Pure 水的硫二氧化物的移动,当为 SO2 的分离的二种膜的 absorbents.The 表演以与增加的吸收剂 concentration.Upon 增加的 SO2 的移动的吸收剂答案, SO2 的集中,和feed 流动 rate.The 效率的集中被评估, NaOH 答案和 MDEA | Han Yongjia Wang Shuli Li Hui Xi Chunman Zhou Shidong | 2009 | China Petroleum Processing & Petrochemical Technology2009，11，3： | 3 |
| 9 | Experimental Investigation on Promoting Effect of Composite Promoting Agents on Natural Gas Hydrate Formation显示文摘An experiment on effects of composite promoting agents composed of surfactants and liquid hydrocarbons on hydrate formation was conducted and the hydrate formation temperature,pressure,induction time and rate in the presence of different composite promoting agent packages were measured.The surfactants used covered sodium dodecyl sulfate(SDS),sodium dodecyl benzene sulfonate(SDBS) and 2-octyl sodium dodecyl sulfate(GC20S),and the liquid hydrocarbon additives utilized included cyclopentane(CP) and methyl cyclohexane(MCH).It appeared that all these combinations of composite promoting agents could promote hydrate formation.The type II hydrate formation conditions using composite promoting agents composed of CP and GC20S were the mildest and the induction time was the shortest;whereas the type H hydrates formation conditions using composite promoting agents composed of MCH and GC20S were the mildest and the induction time was also the shortest. | Wang Shuli Wei Mingjiao Li Entian Zhou Shidong | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，1： | 3 |
| 10 | Enhancement of Rhodobacter sphaeroides growth and carotenoid production through biostimulation显示文摘Bacillus thuringiensis/cereus L2 was added as a biostimulant to enhance the biomass accumulation and carotenoid yield of Rhodobacter sphaeroides using wastewater as the culturing medium. Results showed that biostimulation could significantly enhance the R. sphaeroides biomass production and carotenoid yield. The optimal biostimulant proportion was 40 μL(about 6.4 × 105CFU). Through the use of biostimulation, chemical oxygen demand removal, R. sphaeroides biomass production, carotenoid concentration, and carotenoid yield were improved by 178%, 67%, 214%, and 70%, respectively. Theoretical analysis revealed that there were two possible reasons for such increases. One was that biostimulation enhanced the R. sphaeroides wastewater treatment efficiency. The other was that biostimulation significantly decreased the peroxidase activity in R. sphaeroides. The results showed that the highest peroxidase activity dropped by 87% and the induction ratio of the RSP_3419 gene was 3.1 with the addition of biostimulant. The enhanced carotenoid yield in R. sphaeroides could thus be explained by a decrease in peroxidase activity. | Shuli Liu Guangming Zhang Xiangkun Li Pan Wu Jie Zhang | 2015 | Journal of Environmental Sciences2015，27，7： | 3 |
| 11 | The automobile steel of the third generation in B-pillar reinforced panel显示文摘The fundamental research and industry trials of the third generation automobile steel QP980 were introduced in this paper,including chemical ingredient,mechanical properties,microstructure,forming limit and basic performance parameters.The application of QP steel of the B-pillar was researched,and the QP980,DP600 and hot forming steel were compared in the aspect of formability,safety and cost.The results showed that the QP980 replacing DP600 steel single piece can reduce the weight by 2.4 kg.The security and performance is basically the same as that of hot forming steel using 22MnB5,and the cost is reduced by 30%. | Du Huijun Li Shuli Yang Jie Yang Hongxin Bai Kebin | 2012 | Engineering Sciences2012，10，6： | 2 |
| 12 | Near Infrared Star Centroid Detection by Area Analysis of Multi-Scale Super Pixel Saliency Fusion Map显示文摘The centroid location of a near infrared star always deviates from the real center due to the effects of surrounding radiation. To determine a more accurate center of a near infrared star, this paper proposes a method to detect the star's saliency area and calculate the star's centroid via the pixels only in this area, which can greatly decrease the effect of the radiation. During saliency area detection, we calculated the boundary connectivity and gray similarity of every pixel to estimate how likely it was to be a background pixel. Aiming to simplify and speed up the calculation process, we divided the near infrared starry sky image into super pixel maps at multi-scale by Simple Linear Iterative Clustering(SLIC). Second, we detected the saliency map for every super pixel map of the image. Finally, we fused the saliency maps according to a weighted coefficient that is determined by the least square method. For the images used in our experiment, we set the multi-scale super pixel numbers to 100, 150,and 200. The results show that our method can obtain an offset variance of less than 0.27 for the center coordinates compared to the labelled centers. | Xiaohu Yuan Shaojun Guo Chunwen Li Bin Lu Shuli Lou | 2019 | Tsinghua Science and Technology2019，24，3： | 2 |
| 13 | Research progress of rare earth separation methods and technologies显示文摘Strategical elements,such as rare earth elements,play a crucial role in the industry,especially in producing high-tech materials.Major global industries have developed a strong dependence on rare earth materials.Every year,there are innovations in industries such as modern technology,green energy,or communications technology,which need more strategic metals to improve investment profitability.This article reviews advances in rare earth separation methods and techniques to guide and recommend the best extractants,depending on leaching conditions and the final target product.Each method for separating and extracting agents is individually revised in terms of the mechanism and interaction of providing rare earth elements.This paper also evaluates past and current trends of these methods and technical extractants and identifies their strengths and weaknesses. | Mory Traore Aijun Gong Yiwen Wang Lina Qiu Yuzhen Bai Weiyu Zhao Yang Liu Yi Chen Ying Liu Huilin Wu Shuli Li Yueyi You | 2023 | Journal of Rare Earths2023，41，2： | 2 |
| 14 | KLF7 promotes preadipocyte proliferation via activation of the Akt signaling pathway by Cis-regulating CDKN3显示文摘Krüppel-like transcription factor 7(KLF7)promotes preadipocyte proliferation;however,its target gene in this process has not yet been identified.Using KLF7 ChIP-seq analysis,we previously showed that a KLF7-binding peak is present upstream of the cyclin-dependent kinase inhibitor 3 gene(CDKN3)in chicken preadipocytes.In the present study,we identify CDKN3 as a target gene of KLF7 that mediates the effects of KLF7 on preadipocyte proliferation.Furthermore,5′-truncating mutation analysis shows that the minimal promoter is located between nt–160 and nt–7(relative to the translation initiation codon ATG)of CDKN3.KLF7 overexpression increases CDKN3 promoter activity in the DF-1 and immortalized chicken preadipocyte(ICP1)cell lines.Deletion of the putative binding site of KLF7 abolishes the promotive effect of KLF7 overexpression on CDKN3 promoter activity.Moreover,CDKN3 knockdown and overexpression assays reveal that CDKN3 enhances ICP1 cell proliferation.Flow cytometry analysis shows that CDKN3 accelerates the G1/S transition.Furthermore,we find that KLF7 promotes ICP1 cell proliferation via Akt phosphorylation by regulating CDKN3.Taken together,our results suggest that KLF7 promotes preadipocyte proliferation by activating the Akt signaling pathway by cis-regulating CDKN3,thus driving the G1/S transition. | Ziqiu Jia Zhao Jin Shuli Shao Hu Xu Wen Li Mahmood Khan Weiyu Wang Weiwei Zhang Yingning Sun | 2022 | Acta Biochimica et Biophysica Sinica2022，54，10： | 2 |
| 15 | Wearable and flexible electrochemical sensors for sweat analysis:a review显示文摘Flexible wearable sweat sensors allow continuous,real-time,noninvasive detection of sweat analytes,provide insight into human physiology at the molecular level,and have received significant attention for their promising applications in personalized health monitoring.Electrochemical sensors are the best choice for wearable sweat sensors due to their high performance,low cost,miniaturization,and wide applicability.Recent developments in soft microfluidics,multiplexed biosensing,energy harvesting devices,and materials have advanced the compatibility of wearable electrochemical sweat-sensing platforms.In this review,we summarize the potential of sweat for medical detection and methods for sweat stimulation and collection.This paper provides an overview of the components of wearable sweat sensors and recent developments in materials and power supply technologies and highlights some typical sensing platforms for different types of analytes.Finally,the paper ends with a discussion of the challenges and a view of the prospective development of this exciting field. | Fupeng Gao Chunxiu Liu Lichao Zhang Tiezhu Liu Zheng Wang Zixuan Song Haoyuan Cai Zhen Fang Jiamin Chen Junbo Wang Mengdi Han Jun Wang Kai Lin Ruoyong Wang Mingxiao Li Qian Mei Xibo Ma Shuli Liang Guangyang Gou Ning Xue | 2023 | Microsystems & Nanoengineering2023，9，1： | 2 |
| 16 | Structure and properties of nanoporous FePt fabricated by dealloying a melt-spun Fe(60)Pt(20)B(20)alloy and subsequent annealing显示文摘A nanoporous FePt alloy has been fabricated by dealloying a melt-spun Fe(60)Pt(20)B(20)alloy composed of nanoscale amorphous and face-centered-cubic FePt(fcc-FePt)phases in H2 SO4 aqueous solution.The nanoporous alloy consists of single fcc-FePt phase with an Fe/Pt atomic ratio of about 55.3/44.7,and possesses a uniform interpenetrating ligament-channel structure with average ligament and pore sizes of 27 nm and 12 nm,respectively.The nanoporous fcc-FePt alloy shows soft magnetic characteristics with a saturation magnetization of 37.9 emu/g and better electrocatalytic activity for methanol oxidation than commercial Pt/C in acidic environment.The phase transformation from disordered fcc-Fe Pt into ordered face-centered-tetragonal FePt(L10-FePt)in the nanoporous alloy has been realized after annealing at823-943 K for 600 s.The volume fraction of the L10-FePt phase in the alloy increases with the rise of annealing temperature,which results in the enhancements of coercivity and saturation magnetization from 0.14 kOe and 38.5 emu/g to 8.42 kOe and 51.4 emu/g,respectively.The ligament size of the samples is increased after annealing. | Dianguo Ma Yingmin Wang Yanhui Li Rie Y·Umetsu Shuli Ou Kunio Yubuta Wei Zhang | 2020 | Journal of Materials Science & Technology2020，36，1： | 2 |
| 17 | Cloning of fiber-specific cDNAs and their structural variations in 4 fiber mutants显示文摘A mRNA preferentially expressed in cotton fiber was cloned from fiber total RNA of normal upland cotton TM-1 (wild-type) by using RT-PCR and corresponding cDNA (signed as TM-E6) was sequenced. TM-E6 gene had no intron and contained an open reading frame of 771 bp long, and might encode a peptide of 246 amino acids. Other 4 genes, Fl-E6, Li-E6, N-E6 and Bl-E6, which were homologous to TM-E6 gene, were also isolated from 4 fiber mutants of Fiberless Xu-zhou 142, Ligon lintless, Naked seed and Brown lint, respectively. Sequence analysis of each of these mutant genes revealed many variations in structure and nu-cleotide composition of gene when compared with the sequence of TM-E6 gene. (i) There was a changeable repetitive segment in which GGCTCA (Gly-Ser) was repeated 3-5 times between the 82nd and the 93rd codons in different mutant genes. Since the change of Gly-Ser repetitive segment occurred not only in the mutants but also in the wild-type cotton, the repeat frequency might not be associated with the | WANG Xuede ZHU Yuxian Jl Daofan JIANG Shuli LI Yueyou | 2001 | Chinese Science Bulletin2001，46，3： | 2 |
| 18 | Global patterns of the dynamics of soil carbon and nitrogen stocks following afforestation: a meta- analysis显示文摘 | LI Dejun NIU Shuli LUO Yiqi | 2012 | New Phytologist2012，195，1： | 1 |
| 19 | Multi-sensor distributed fusion filtering for networked systems with different delay and loss rates显示文摘 | Li Na Sun Shuli Ma Jing | 2014 | Digital Signal Processing2014，34，1： | 1 |
| 20 | High valence state of Ni and Mo synergism in NiS_(2);MoS_(2)hetero-nanorods catalyst with layered surface structure for urea electrocatalysis显示文摘High valence state species are significant in the energy-relevant electrochemical oxidation reactions.Herein,the high active state of Ni^(3+)formation induced by Mo^(6+)and their efficient synergism in NiS_(2)-MoS_(2)hetero-nanorods powder catalyst with the rough layered structure are demonstrated,as proof of concept,for the urea-assisted water electrolysis.This catalyst can be derived from the sulfidation of NiMoO_(4) nanorods that can realize individual metal sulfides sufficiently mixing at a domain size in the nanoscale which creates lots of active sites and nanointerfaces.The high valence state of Mo^(6+)and Ni^(3+)formation and increased conductive phase of 1 T MoS_(2)in the hetero-nanorods compared to the counterpart pure phases are revealed by spectral study and microscopic analysis;high electrochemical surface area and active site exposure are found due to the nano-interface formation and layered rough nanosheets over the surface of nanorods.They show much higher catalytic performance than their pure phases for urea oxidation,including high catalytic activity,stability,charge transfer ability and catalytic kinetics resulting from more active Ni^(3+)species formation and electronic synergism of high valence metals.Transformation of 1 T MoS_(2)to Mo^(6+)and increased amount of Mo^(6+)and Ni^(3+)after stability test indicate their involvement and synergism for the catalysis reaction.The current work offers a novel understanding of the synergistic effect based on the high valence state synergism for heterogeneous catalysts in electrocatalysis. | Shuli Wang Linyu Zhao Jiaxin Li Xinlong Tian Xiang Wu Ligang Feng | 2022 | Journal of Energy Chemistry2022，31，3： | 1 |
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