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| 1 | Effect of nutritional counselling on hepatic,muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease显示文摘AIM: To assess the effectiveness of the current UK clinical practice in reducing hepatic fat (IHCL). METHODS: Whole body MRI and 1H MRS were obtained, before and after 6 mo nutritional counselling, from liver, soleus and tibialis muscles in 10 subjects with non-alcoholic fatty liver disease (NAFLD). RESULTS: A 500 Kcal-restricted diet resulted in an average weight loss of 4% (-3.4 kg,) accompanied by significant reductions in most adipose tissue (AT) depots, including subcutaneous (-9.9%), abdominal subcutaneous (-10.2%) and intra-abdominal-AT (-11.4%). Intramyocellular lipids (IMCL) were significantly reduced in the tibialis muscle (-28.2%). Decreases in both IHCL (-39.9%) and soleus IMCL (-12.2%) content were also observed, although these were not significant. Several individuals showed dramatic decreases in IHCL, while others paradoxically showed increases in IHCL content. Changes in body composition were accompanied by improvements in certain liver function tests: serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Significant correlations were found between decreases in IHCL and reductions in both intra-abdominal and abdominal subcutaneous AT. Improvements in liver function tests were associated with reductions in intra-abdominal AT, but not with changes in IHCL. CONCLUSION: This study shows that even a very modest reduction in body weight achieved through lifestyle modification can result in changes in body fat depots and improvements in LFTs. | E Louise Thomas Audrey E Brynes Gavin Hamilton Nayna Patel Adam Spong Robert D Goldin Gary Frost Jimmy D Bell Simon D Taylor-Robinson | 2006 | World Journal of Gastroenterology2006，12，36： | 13 |
| 2 | A phase inversion polymer coating to prevent swelling and spalling of clay fines in coal seam gas wells显示文摘 | Lei Ge Christopher Hamilton Rahmah Tasha Febrina Victor Rudolph Thomas E. Rufford | 2018 | International Journal of Coal Science & Technology2018，5，2： | 3 |
| 3 | Impact of experience with a retrograde-viewing device on adenoma detection rates and withdrawal times during colonoscopy: the Third Eye Retroscope study group显示文摘 | Daniel C. DeMarco Elizabeth Odstrcil Luis F. Lara David Bass Chase Herdman Timothy Kinney Kapil Gupta Leon Wolf Thomas Dewar Thomas M. Deas Manoj K. Mehta M. Badar Anwer Randall Pellish J. Kent Hamilton Daniel Polter K. Gautham Reddy Ira Hanan | 2010 | Gastrointestinal Endoscopy2010，，3： | 2 |
| 4 | Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study 显示文摘 | Thomas EL Hamilton G Patel N | 2005 | Gut2005，54，1： | 1 |
| 5 | Elective groin irradiation is not indicated for patients with adenocarcinoma of the rectum extending to the anal canal显示文摘 | Noah Taylor Christopher Crane John Skibber Barry Feig Lee Ellis Jean-Nicholas Vauthey Stanley Hamilton Karen Cleary Ronelle Dubrow Thomas Brown Robert Wolff Paulo Hoff Nicholas Sanfilippo Nora Janjan | 2001 | International Journal of Radiation Oncology Biology Physics2001，，3： | 1 |
| 6 | Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study 显示文摘 | Thomas EL Hamilton G Patel N | 2005 | Gut2005，54，1： | 1 |
| 7 | Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study显示文摘 | Thomas EL Hamilton G Patel N O'Dwyer R Dore CJ Goldin RD | 2005 | Gut2005，54，1： | 1 |
| 8 | Hepatic triglyceride content and its relation to body adiposity:a magnetic resonance imaging and proton magnetic resonance spectroscopy study显示文摘 | Thomas EL Hamilton G Patel N | 2005 | Gut2005，54，1： | 1 |
| 9 | Tension wood formation following release of upland oak abvance reproduction 显示文摘 | Hamilton J R Thomas C K Carvell K L | 1985 | Wood and Fiber Science1985，17，3： | 1 |
| 10 | Hepatic triglyceride content and its relation to body adiposity:a magnetic resonance imaging and proton magnetic resonance spectroscopy study显示文摘 | Thomas EL Hamilton G Patel N | 2005 | Gut2005，54，1： | 1 |
| 11 | Hepatic triglyceride content and its relation to body adiposity, a magnetic resonance in aging and proton magnetic resonance spectroscopy study 显示文摘 | THOMAS E L HAMILTON G PATEL N | 2005 | Gut2005，54，： | 1 |
| 12 | Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study 显示文摘 | Thomas EL Hamilton G Patel N | 2005 | Gut2005，54，1： | 1 |
| 13 | Hepatic triglyceride content and its relation to body adiposity:a magnetie resonance imaging and proton magnetie reasonance spectroscopy study显示文摘 | Thomas EL Hamilton G Patel N | 2005 | Cut2005，54，1： | 1 |
| 14 | Hepatic triglyc- eride content and its relation to body adiposity:a magnetic reso- nance imag/ng and proton magnetic resonance spectroscopy study 显示文摘 | THOMAS E L HAMILTON G PATELN | 2005 | Gut2005，54，1： | 1 |
| 15 | Altered adiposity after extremely preterm birth显示文摘 | Uthaya S Thomas EL Hamilton G | | 0，，02： | 1 |
| 16 | Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells显示文摘 | Styblo M Del Razo L M Vega L Germolec D R LeCluyse E L Hamilton G A Reed W Wang C Cullen W R Thomas D J | | 0，，06： | 1 |
| 17 | Cerebral immune activation in chronic hepatitis C infection: A magnetic resonance spectroscopy study显示文摘 | Daniel M. Forton Gavin Hamilton Joanna M. Allsop Vijay P. Grover Keith Wesnes Catherine O’Sullivan Howard C. Thomas Simon D. Taylor-Robinson | 2008 | Journal of Hepatology2008，，3： | 1 |
| 18 | The degradation of the scorecard over the business cycle 显示文摘 | Crook J N Hamilton R Thomas L C | 1992 | IMA Journal of Mathematics Applied in Business and Industry1992，，4： | 1 |
| 19 | Upgrade of the Glasgow photon tagging spectrometer for Mainz MAMI-C显示文摘 | J. C. McGeorge J. D. Kellie J. R. M. Annand J. Ahrens I. Anthony A. Clarkson D. J. Hamilton P. S. Lumsden E. F. McNicoll R. O. Owens G. Rosner A. Thomas | 2008 | The European Physical Journal A2008，，1： | 1 |
| 20 | Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis显示文摘 | Lisa A. Beck Diamant Tha?i Jennifer D. Hamilton Neil M. Graham Thomas Bieber Ross Rocklin Jeffrey E. Ming Haobo Ren Richard Kao Eric Simpson Marius Ardeleanu Steven P. Weinstein Gianluca Pirozzi Emma Guttman-Yassky Mayte Suárez-Fari?as Melissa D. Hager Ne | 2014 | The New England Journal of Medicine2014，，： | 1 |
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