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| 1 | 口服西地那非疗法治疗严重肺动脉高压的效果研究显示文摘 | Singh TP Rohit M Grover A 菅鑫妍 | 2006 | 中国处方药2006,,8: | 49 |
| 2 | Positive aspects of caregiving in schizophrenia: A review显示文摘Schizophrenia is a severe mental illness which is associated with significant consequences for both the patients and their relatives. Due to chronicity of the illness, the relatives of patients of schizophrenia have to bear the main brunt of the illness. Studies across the world have evaluated various aspects of caregiving and caregivers such as burden, coping, quality of life, social support, expressed emotions, and psychological morbidity. In general the research has looked at caregiving as a negative phenomenon, however, now it is increasingly recognised that caregiving is not only associated with negative consequences only, also experience subjective gains and satisfaction. This review focus on the conceptual issues, instruments available to assess the positive aspects of caregiving and the various correlates of positive aspects of caregiving reported in relation to schizophrenia. The positive aspect of caregiving has been variously measured as positive caregiving experience, caregiving satisfaction, caregiving gains and finding meaning through caregiving scale and positive aspects of caregiving experience. Studies suggests that caregivers of patients with schizophrenia and psychotic disorders experience caregiving gains(in the form of becoming more sensitive to persons with disabilities, clarity about their priorities in life and a greater sense of inner strength), experience good aspects of relationship with the patient, do have personal positive experiences. Some of the studies suggest that those who experience greater negative caregiving experience also do experience positive caregiving experience. | Parmanand Kulhara Natasha Kate Sandeep Grover Ritu Nehra | 2012 | World Journal of Psychiatry2012,2,3: | 10 |
| 3 | Virtual reality simulation in endoscopy training:Current evidence and future directions显示文摘Virtual reality simulation is becoming the standard when beginning endoscopic training. It offers various benefits including learning in a low-stakes environment, improvement of patient safety and optimization of valuable endoscopy time. This is a review of the evidence surrounding virtual reality simulation and its efficacy in teaching endoscopic techniques. There have been 21 randomized controlled trials(RCTs) that have investigated virtual reality simulation as a teaching tool in endoscopy. 10 RCTs studied virtual reality in colonoscopy, 3 in flexible sigmoidoscopy, 5 in esophagogastroduodenoscopy, and 3 in endoscopic retrograde cholangiopancreatography. RCTs reported many outcomes including distance advanced in colonoscopy, comprehensive assessment of technical and non-technical skills, and patient comfort. Generally, these RCTs reveal that trainees with virtual reality simulation based learning improve in all of these areas in the beginning of the learning process. Virtual reality simulation was not effective as a replacement of conventional teaching methods. Additionally, feedback was shown to be an essential part of the learning process. Overall, virtual reality endoscopic simulation is emerging as a necessary augment to conventional learning given the ever increasing importance of patient safety and increasingly valuable endoscopy time; although work is still needed to study the nuances surrounding its integration into curriculum. | Tahrin Mahmood Michael Anthony Scaffidi Rishad Khan Samir ChANDra Grover | 2018 | World Journal of Gastroenterology2018,24,48: | 10 |
| 4 | Assessment scales for delirium: A review显示文摘Over the years many scales have been designed for screening, diagnosis and assessing the severity of delirium. In this paper we review the various instruments available to screen the patients for delirium, instruments available to diagnose delirium, assess the severity, cognitive functions, motoric subtypes, etiology and associated distress. Among the various screening instruments, NEECHAM confusion scale and delirium observation scale appear to be most suitable screening instrument for patients' in general medical and surgical wards, depending on the type of rater(physician or nurse). In general, the instruments which are used for diagnosis [i.e., confusion assessment method(CAM), CAM for intensive care unit(CAM-ICU), Delirium Rating Scale-revised version(DRS-R-98), memorial selirium assessment scale, etc. ] are based on various Diagnostic and Statistical Manual criteria and have good to excellent reliability and fair to good validity. Among the various diagnostic instruments, CAM is considered to be most useful instrument because of its accuracy, brevity, and ease of use by clinicians and lay interviewers. In contrast, DRS-R-98 appears to be a comprehensive instrument useful for diagnosis, severity rating and is sensitive to change and hence can be used for monitoring patients over a period. In the ICU setting, evidence suggests that CAM-ICU and Nursing Delirium Screening Scale had comparable sensitivities, but CAM-ICU has higher specificity. With regard to assessment of delirium in pediatric age group, certain instruments like Pediatric Anesthesia Emergence Delirium scale and pediatric CAM-ICU has been designed and have been found to be useful. | Sandeep Grover Natasha Kate | 2012 | World Journal of Psychiatry2012,2,4: | 9 |
| 5 | Lubiprostone vs Senna in postoperative orthopedic surgery patients with opioid-induced constipation:A double-blind,active-comparator trial显示文摘AIM:To investigate the efficacy of lubiprostone compared to Senna on bowel symptoms and constipation in post-operative orthopedic patients treated with opioids.METHODS:In this double blind,randomized,active comparator trial,adults who required opioids for analgesia following orthopedic procedures and who were admitted in inpatient rehabilitation were randomized following baseline assessments to lubiprostone(Amitza),orally twice aday or Senna(generic)two capsules administered daily for six days.Subjects were assessed using the patient assessment of constipation(PAC)-symptoms(PAC-SYM)and the PAC-quality of life(PAC-QOL)scales measured at baseline and Day 7;Subjects were assessed daily for secondary measures included the Bristol stool scale bowel consistency,specific bowel symptom score(Nausea,cramping,straining,completeness,abdominal pain,time per lavatory attempt,assistance needed),adverse events and rescue medications required.Function was measured using the functional independence measure(FIM)at admission and discharge;length of stay(LOS)and missed treatments due to gastrointestinal symptoms were also assessed.RESULTS:64 adults were enrolled;56 participants(28 in each group)had baseline and follow up measures and were included in the intention to treat(ITT)analyses.43 participants completed the study,21 in the active lubiprostone and 22 in the active Senna group.The mean age of the participants was 71.5years(SD=11.4 years,range:28-96 years).In the ITT analyses,participants showed significant improvement in bowel symptoms as measured by the PACSYM(mean±SD,-0.28±0.60,range:-1-2.33)and PAC-QOL(mean±SD,0.33±0.81,range:-1.5-2.0)over time,but there were no significant differences between the lubiprostone and Senna groups in mean change in the PAC-SYM(-0.20±0.60 vs-0.36±0.61,P=0.61 respectively)or the PAC-QOL(0.29±0.76 vs0.37±0.87,P=0.61 respectively).The mean change in each bowel symptom also did not significantly differ between treatment groups on ITT analyses,except for completeness of bowel movement,with the Senna group showing greater negative mean change in bowel movement completeness(-0.56±1.01 vs-2.00±1.41,P=0.03)and for reduction of abdominal pain,favoring Senna(-0.14±0.73 vs-0.73±1.08,P=0.04).Fifteen(75%)participants in the lubiprostone and in the Senna group requested rescue treatments.Participants made significant functional improvement from admission to discharge over a median LOS of 12 d,with a mean FIM change of 29.13±13.58 and no significant between group differences(27.0±9.2 vs 31.5±16.6,P=0.27).CONCLUSION:Both lubiprostone and Senna improved constipation-related symptoms and QOL in opioid-induced constipation,with no significant between-group differences. | Christina M Marciniak Santiago Toledo Jungwhalia Lee Michael Jesselson Jillian Bateman Benjamin Grover Joy Tierny | 2014 | World Journal of Gastroenterology2014,20,43: | 7 |
| 6 | Fault diagnosis of spur gearbox based on random forest and wavelet packet decomposition显示文摘这份报纸在刺激 gearboxes 为多班差错诊断探讨一个随机的森林分类器的发展。颤动信号条件参数被与多重母亲小浪,和系数精力内容使用小浪包分解首先提取因为终端节点为分类问题被用作输入特征。然后,通过发现最好的空间为树的数字和随机的特征的数字珍视的参数的研究被执行。这样,为申请的母亲小浪的最好的集合被识别,最好的特征通过随机的森林分类器的内部评价被选择。结果证明建议方法在模型在分类精确性,和高效率和坚韧性到达了 98.68% 。 | Diego CABRERA Fernando SANCHO Rene-Vinicio SANCHEZ Grover ZURITA Mariela CERRADA Chuan LI Rafael E. VASQUEZ | 2015 | Frontiers of Mechanical Engineering2015,10,3: | 5 |
| 7 | Gender differences in caregiving among family- caregivers of people with mental illnesses显示文摘All over the world women are the predominant providers of informal care for family members with chronic medical conditions or disabilities, including the elderly and adults with mental illnesses. It has been suggested that there are several societal and cultural demands on women to adopt the role of a family-caregiver. Stress-coping theories propose that women are more likely to be exposed to caregiving stressors, and are likely to perceive, report and cope with these stressors differently from men. Many studies, which have examined gender differences among family-caregivers of people with mental illnesses, have concluded that women spend more time in providing care and carry out personal-care tasks more often than men. These studies have also found that women experience greater mental and physical strain, greater caregiver-burden, and higher levels of psychological distress while providing care. However, almost an equal number of studies have not found any differences between men and women on these aspects. This has led to the view that though there may be certain differences between male and female caregivers, most of these are small in magnitude and of doubtful clinical significance. Accordingly, caregivergender is thought to explain only a minor proportion of the variance in negative caregiving outcomes. A similar inconsistency characterizes the explanations provided for gender differences in caregiving such as role expectations, differences in stress, coping and social support, and response biases in reporting distress. Apart from the equivocal and inconsistent evidence, there are other problems in the literature on gender differences in caregiving. Most of the evidence has been derived from studies on caregivers of elderly people who either suffer from dementia or other physical conditions. Similar research on other mental illnesses such as schizophrenia or mood disorders is relatively scarce. With changing demographics and social norms men are increasingly assuming roles as caregivers. However, the experience of men while providing care has not been explored adequately. The impact of gender on caregiving outcomes may be mediated by several other variables including patient-related factors, socio-demographic variables, and effects of kinship status, culture and ethnicity, but these have seldom been considered in the research on gender differences. Finally, it is apparent that methodological variations in samples, designs andassessments between studies contribute a great deal to the observed gender differences. This review highlights all these issues and concludes that there is much need for further research in this area if the true nature of gender differences in family-caregiving of mental illnesses is to be discerned. | Nidhi Sharma Subho Chakrabarti Sandeep Grover | 2016 | World Journal of Psychiatry2016,6,1: | 4 |
| 8 | Liver transplantation for hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is the commonest primary malignancy of the liver. It usually occurs in the setting of chronic liver disease and has a poor prognosis if untreated. Orthotopic liver transplantation (OLT) is a suitable therapeutic option for early,unresectable HCC particularly in the setting of chronic liver disease. Following on from disappointing initial results,the seminal study by Mazzaferro et al in 1996 established OLT as a viable treatment for HCC. In this study,the 'Milan criteria' were applied achieving a 4-year survival rate similar to OLT for benign disease. Since then various groups have attempted to expand these criteria whilst maintaining long term survival rates. The technique of living donor liver transplantation has evolved over the past decade,particularly in Asia,and published outcome data is comparable to that of OLT. This article will review the evidence,indications,and the future direction of liver transplantation for liver cancer. | Sudeep Tanwar Shahid A Khan Vijay Paul Bob Grover Catherine Gwilt Belinda Smith Ashley Brown | 2009 | World Journal of Gastroenterology2009,15,44: | 4 |
| 9 | Simulation in endoscopy:Practical educational strategies to improve learning显示文摘In gastrointestinal endoscopy, simulation-based training can help endoscopists acquire new skills and accelerate the learning curve. Simulation creates an ideal environment for trainees, where they can practice specific skills, perform cases at their own pace, and make mistakes with no risk to patients. Educators also benefit from the use of simulators, as they can structure training according to learner needs and focus solely on the trainee. Not all simulation-based training,however, is effective. To maximize benefits from this instructional modality,educators must be conscious of learners' needs, the potential benefits of training,and associated costs. Simulation should be integrated into training in a manner that is grounded in educational theory and empirical data. In this review, we focus on four best practices in simulation-based education: deliberate practice with mastery learning, feedback and debriefing, contextual learning, and innovative educational strategies. For each topic, we provide definitions,supporting evidence, and practical tips for implementation. | Rishad Khan Michael A Scaffidi Samir C Grover Nikko Gimpaya Catharine M Walsh | 2019 | World Journal of Gastrointestinal Endoscopy2019,11,3: | 3 |
| 10 | 上颌前牙区即刻种植修复的红白美学评分显示文摘目的:应用红色美学评分(PES)和白色美学评分(WES)评价上颌前牙即刻种植体与即刻修复的美学效果。材料与方法:回顾性分析患者资料。该评估由两名观察者使用12个评估标准进行。结果:在53名患者(22名男性与31名女性)的53例图像中,红色美学评分PES的均值为8.63±2.4(范围1-14),而白色美学评分WES均值为6.92±1.67(范围,2-10)。近中牙龈乳头得到最大的PES均值为(1.39±0.4)。远端牙龈乳头得到最小的PES均值(0.87±0.54)。牙齿表面得到最大的WES均值为(1.54土0.34)且牙齿形态得到最小的WES均值为(1.25土0.43)。结论:根据PES/WES值评估.针对上颌前牙,配合即刻修复的即刻种植体具有良好的临床美学效果。PES和WES评估值显示出较强的观察者本身差异一致性,但较弱的观察者间差异一致性。 | Guaracilei Maciel Vidigal Mario Groisman Victor Grover Rene Clavijo Igor Guimaraes Barros Paulinelli Santos Ricardo Guimaraes Fischer 杨宗澄(译) 徐新(审) | 2019 | 中国口腔医学继续教育杂志2019,22,2: | 3 |
| 11 | Importance of blood cellular genomic profile in coronary heart disease显示文摘 | M. Iqbal Baba Deepak Kaul Anil Grover | 2006 | Journal of Biomedical Science2006,,1: | 3 |
| 12 | A Framework for Examining the Interface between Operations Research and Information Systems:Implications for Research in the New Millennium显示文摘 | Grover V Malhotra MK | 1999 | Decision Science1999,,4: | 2 |
| 13 | Percutaneous coronary intervention for acute myocardial infarction in a patient with dextrocardia显示文摘Situs inversus with dextrocardia is a rare congenital anomaly.There are limited published case reports of successful percutaneous coronary intervention(PCI) in these patients who have atherosclerotic coronary artery disease,especially when presenting with acute myocardial infarction.PCI is technically difficult be-cause of mirror image dextrocardia.We hereby de-scribe a 48-yr-old female,who had acute inferior wall myocardial infarction and underwent successful emer-gency primary coronary angioplasty and stenting of a proximally occluded right coronary artery.Technical details about PCI are discussed. | Rajesh Vijayvergiya Anil Grover | 2010 | World Journal of Cardiology2010,2,4: | 2 |
| 14 | On the fiftieth anniversary Postinfectious irritable bowel syndrome: mechanisms related to pathogens显示文摘 | M. Grover M. Camilleri K. Smith D. R. Linden G. Farrugia | 2014 | Neurogastroenterol. Motil2014,,2: | 2 |
| 15 | Rapid prenatal diagnosis of congenital toxoplasma infection by using polymetase chain reaction 显示文摘 | Grover CM Thulliez P Remington JS | 1990 | J Clin Microbiol1990,28,: | 2 |
| 16 | Inhibition of proliferation of retinal vascular endothelial cells more effectively than choroidal vascular endothelial cell proliferation by bevacizumab显示文摘● AIM: To evaluate the differential inhibitory effects of bevacizumab on cell proliferation of vascular endothelial growth factor(VEGF)-stimulated choroidal vascular endothelial cells(CVECs) and retinal vascular endothelial cells(RVECs) in vitro.● METHODS: VEGF(400 ng/m L) enriched CVECs and RVECs were treated with escalating doses of bevacizumab(0.1, 0.5, 1, 1.5 and 2 mg/m L). Cell proliferation changes were analyzed with WST-1 assay and trypan blue exclusion assay at 48, 72 h and 1wk. Morphological changes were recorded with bright field microscopy.● RESULTS: VEGF enriched RVECs showed significantly more decline of cell viability than CVECs after bevacizumab treatment. One week after treatment, RVEC cell proliferation decreased by 29.7%, 37.5%, 52.8%, 35.9% and 45.6% at 0.1, 0.5, 1.0, 1.5 and 2 mg/m L bevacizumab respectively compared to CVEC proliferation decrease of 4.1%, 7.7%, 2.4%, 4.1% and 17.7%(P<0.05) by WST-1 assay. Trypan blue exclusion assay also revealed similar decrease in RVEC proliferation of 20%, 60%, 73.3%, 80% and 93.3% compared to CVEC proliferation decrease of 4%, 12%, 22.9%, 16.7% and 22.2% respectively(P<0.05). The maximum differential effect between the two cell types was observed at bevacizumab doses of 1.0 and 1.5 mg/mL at all time points. RVECs were 22 fold more sensitive(P<0.01) compared to CVECs(52.8% vs 2.4%) at concentration of 1.0 mg/mL, and 8.7 fold more at 1.5 mg/mL(35.9% vs 4.1%) 1wk after treatment(P<0.05 respectively).● CONCLUSION: VEGF-enriched RVECs are more susceptible to bevacizumab inhibition than CVECs at clinically used dosage of 1.25 mg and this differential sensitivity between two cell types should be taken into consideration in dosage selection. | Bharani Krishna Mynampati Kumar Sambhav Sandeep Grover Kakarla V.Chalam | 2017 | International Journal of Ophthalmology(English edition)2017,10,1: | 2 |
| 17 | Small intestine gastrointestinal stromal tumors显示文摘 | Shilpa Grover Stanley W. Ashley Chandrajit P. Raut | 2012 | Current Opinion in Gastroenterology2012,,2: | 2 |
| 18 | Effects on gastrointestinal functions and symptoms of serotonergic psychoactive agents used in functional gastrointestinal diseases显示文摘 | Madhusudan Grover Michael Camilleri | 2013 | Journal of Gastroenterology2013,,2: | 2 |
| 19 | Modeling effects of oxygen inhibition in mask-based stereolithography显示文摘 | Amit S. Jariwala Fei Ding Aparna Boddapati Victor Breedveld Martha A. Grover Clifford L. Henderson David W. Rosen | 2011 | Rapid Prototyping Journal2011,,3: | 2 |
| 20 | Traditional Indian anti-diabetic plants attenuate progression of renal damage in streptozotocin induced diabetic mice显示文摘 | J.K Grover V Vats S.S Rathi R Dawar | 2001 | Journal of Ethnopharmacology2001,,3: | 2 |