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| 1 | 广汉三星堆遗物坑青铜器的铅同位素比值研究显示文摘四川广汉三星堆遗址的发现,特别是1986年夏三星堆两个遗物坑的发掘,是中国西南地区考古的重大收获。有关报道发表之后,很快引起学界广泛注意,海外一些学者,如Robert W.Bagley和N.Barnard等人曾经多次著文予以评价。数年来,围绕这两个遗物坑的年代、性质以及出土的各种器物,包括数量和艺术质量都十分惊人的青铜器物,考古学界进行了热烈的讨论,发表了大量的研究成果,大大丰富了我们对巴蜀地区古青铜文化的认识。 | 金正耀 马渊久夫 Tom Chase 陈德安 三轮嘉六 平尾良光 赵殿增 | 1995 | 文物1995，，2： | 41 |
| 2 | Neuroprotective effects of human bone marrow mesenchymal stem cells against cerebral ischemia are mediated in part by an anti-apoptotic mechanism显示文摘Transplantation of human bone marrow mesenchymal stem cells(hMSCs) stands as a potent stroke therapy, but its exact mechanism remains unknown. This study investigated the anti-apoptotic mechanisms by which hMSCs exert neuroprotective effects on cerebral ischemia. Primary mixed cultures of rat neurons and astrocytes were cultured and exposed to oxygen-glucose deprivation. A two-hour period of 'reperfusion' in standard medium and normoxic conditions was allowed and immediately followed by hMSCs and/or Bcl-2 antibody treatment. Cell viability of primary rat neurons and astrocytes was determined by 3-(4,5-dimethylthianol-2-yl)-2,5 diphenyl tetrazolium bromide and trypan blue exclusion methods. hMSC survival and differentiation were characterized by immunocytochemistry, while the concentration of Bcl-2 in the supernatant was measured by enzyme-linked immunosorbent assay to reveal the secretory anti-apoptotic function of hMSCs. Cultured hMSCs expressed embryonic-like stem cell phenotypic markers CXCR4, Oct4, SSEA4, and Nanog, as well as immature neural phenotypic marker Nestin. Primary rat neurons and astrocytes were protected from oxygen-glucose deprivation by hMSCs, which was antagonized by the Bcl-2 antibody. However, Bcl-2 levels in the supernatants did not differ between hMSCand non-treated cells exposed to oxygen-glucose deprivation. Neuroprotective effects of hMSCs against cerebral ischemia were partially mediated by the anti-apoptotic mechanisms. However, further studies are warranted to fully elucidate this pathway. | Yuyang Zhang Seongjin Yu Julian P.Tuazon Jea-Young Lee Sydney Corey Lauren Kvederis Chase Kingsbury Yuji Kaneko Cesar V.Borlongan | 2019 | Neural Regeneration Research2019，14，4： | 9 |
| 3 | Fast-tracking regenerative medicine for traumatic brain injury显示文摘Traumatic brain injury remains a global health crisis that spans all demographics,yet there exist limited treatment options that may effectively curtail its lingering symptoms.Traumatic brain injury pathology entails a progression from primary injury to inflammation-mediated secondary cell death.Sequestering this inflammation as a means of ameliorating the greater symptomology of traumatic brain injury has emerged as an attractive treatment prospect.In this review,we recapitulate and evaluate the important developments relating to regulating traumatic brain injury-induced neuroinflammation,edema,and blood-brain barrier disintegration through pharmacotherapy and stem cell transplants.Although these studies of stand-alone treatments have yielded some positive results,more therapeutic outcomes have been documented from the promising area of combined drug and stem cell therapy.Harnessing the facilitatory properties of certain pharmaceuticals with the anti-inflammatory and regenerative effects of stem cell transplants creates a synergistic effect greater than the sum of its parts.The burgeoning evidence in favor of combined drug and stem cell therapies warrants more elaborate preclinical studies on this topic in order to pave the way for later clinical trials. | Brooke Bonsack Matt Heyck Chase Kingsbury Blaise Cozene Nadia Sadanandan Jea-Young Lee Cesar V. Borlongan | 2020 | Neural Regeneration Research2020，15，7： | 5 |
| 4 | Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification显示文摘Heterotopic ossification(HO)is a debilitating condition characterized by the pathologic formation of ectopic bone.HO occurs commonly following orthopedic surgeries,burns,and neurologic injuries.While surgical excision may provide palliation,the procedure is often burdened with significant intra-operative blood loss due to a more robust contribution of blood supply to the pathologic bone than to native bone.Based on these clinical observations,we set out to examine the role of vascular signaling in HO.Vascular endothelial growth factor A(VEGFA)has previously been shown to be a crucial pro-angiogenic and pro-osteogenic cue during normal bone development and homeostasis.Our findings,using a validated mouse model of HO,demonstrate that HO lesions are highly vascular,and that VEGFA is critical to ectopic bone formation,despite lacking a contribution of endothelial cells within the developing anlagen. | Charles Hwang Simone Marini Amanda KHuber David MStepien Michael Sorkin Shawn Loder Chase APagani John Li Noelle DVisser Kaetlin Vasquez Mohamed AGarada Shuli Li Jiajia Xu Ching-Yun Hsu Paul BYu Aaron WJames Yuji Mishina Shailesh Agarwal Jun Li Benjamin Levi | 2019 | Bone Research2019，7，4： | 4 |
| 5 | 中国妇女使用阴道卫生棉条和卫生巾的临床单盲随机比较研究显示文摘目的 通过经期使用卫生棉条及卫生巾的随机性比较,探讨中国妇女使用卫生棉条的安全性。方法 2003-08—2004-07在首都医科大学附属北京友谊医院与上海市计划生育科研所征集300例具有规则月经周期的已婚健康育龄妇女,随机分为卫生棉条组和卫生巾对照组.并在使用产品后的第1、3、6个月经周期后行妇科检查和评分,同时取样行实验室阴道分泌物悬滴试验、氢氧化钾(KOH)试验、细菌性阴道病试验(BV.Blue)、阴道酸碱度(pH)检查。结果 在3次随访中,棉条组外阴和阴道症状发生率为0.8%(1/130)-1.4%(2/144),较卫生巾组发生率0.7%(1/136)-4.1%(6/145)略低,程度亦轻,无一例因此而终止试验。棉条组阴道炎症总感染发生率4.0%(6/150),对照组为4.6%(7/150),两组比较差异无统计学意义(P〉0.05)。试验结束时棉条组慢性宫颈炎的比例为12,3%,较试验开始时的21.3%有所下降,与对照组相似(结束时12.5%,开始时25,3%)。其中轻度宫颈糜烂入选时有27例,研究结束时为12例,且无一例中度或重度宫颈糜烂发生.此结果亦与对照组相似(入选时37例,结束时16例)。结论 卫生棉条未增加阴道感染和宫颈炎症的发生率,并且未加重宫颈炎症的程度,无不良反应,在中国妇女中使用卫生棉条是安全的。 | 靳家玉 王建捷 贺昌海 桂幼伦 周维瑾 David Chase J 武镇忆 曹泽毅 | 2006 | 中国实用妇科与产科杂志2006，22，9： | 3 |
| 6 | 含引流通道的气-液聚结过滤材料的性能试验显示文摘针对空气中油雾的净化问题,对聚结纤维滤料的织物构造提出了一种优化设计。将纤维细度为2μm和6.5μm的不锈钢(SS)纤维滤料及相对应纤维细度的玻璃(G)纤维滤料分别构成内含4个垂直引流通道的多层复合滤料,用气-液聚结过滤性能试验台进行对比测试,计算分析引流通道的构建对滤料捕集效率、阻力特性及品质因数产生的影响。结果表明,在滤层内加插金属网隔片建立若干垂直引流通道对滤料阻力特性有着显著影响,其过滤性能有所改善。在相同条件下,含引流通道的滤料到达阻力稳态阶段需时更长,而且上升过程中瞬时阻力最多可降低30%~50%,品质因数可提高50%~70%。 | 吴伊人 沈恒根 CHASE George G | 2016 | 安全与环境学报2016，16，3： | 2 |
| 7 | Aseismic smart building isolation systems under multi-level earthquake excitations: Part II, energy-dissipation and damage reduction显示文摘基于以前建议的聪明的大楼隔离系统(第一同伴纸) 的性能结果,这后面的研究从精力的看法点验证系统的控制效果驱散和损坏水平度量标准。利用被动 dampers 和半活跃的 resettable 设备的战略上孤立的有多层楼的大楼结构的几个不同模型盒子被分析,基于精力的目标索引被比较。表演比较在地震地面运动记录的现实主义的套房上在统计上计算的 story/structural hysteretic 精力和 story/structural 损坏要求上被进行,代表特定的回来时期概率的地震刺激。再次,半活跃的答案为 resettable 设备的应用显示出重要诺言,提供超越在一致损坏减小的被动系统的优点。这研究的特定的结果在聪明的大楼隔离系统由移开精力的机制包括差别的鉴定,基于在使用的设备的差别。更少的可变性也为半活跃的隔离系统被看见,显示增加的坚韧性。 | Min-Ho CHEY J. Geoffrey CHASE John B. MANDER Athol J. CARR | 2015 | Frontiers of Structural and Civil Engineering2015，9，3： | 2 |
| 8 | Impact of experience with a retrograde-viewing device on adenoma detection rates and withdrawal times during colonoscopy: the Third Eye Retroscope study group显示文摘 | Daniel C. DeMarco Elizabeth Odstrcil Luis F. Lara David Bass Chase Herdman Timothy Kinney Kapil Gupta Leon Wolf Thomas Dewar Thomas M. Deas Manoj K. Mehta M. Badar Anwer Randall Pellish J. Kent Hamilton Daniel Polter K. Gautham Reddy Ira Hanan | 2010 | Gastrointestinal Endoscopy2010，，3： | 2 |
| 9 | Protective Effects of Dimethyl-4,4'-Dimethoxy-5,6,5',6'-Dimethylene Dioxybiphenyl-2,2'-Dicarboxylate on Damages of Isolated Rat Hepatocytes Induced by Carbon Tetrachloride and D-galactosamine显示文摘The rotective effect of biphenyl dimethyl dicarboxylate(DDB)on chemically induced damages was studied in isolated suspended rat hepatocytes.The experimental results showed that DDB(200μg/10^6cells) efficiently protected the hepatocytes against carbon tetrachloride(CCl4 10mmol·L^-1)and D-galactosamine(1mmol·L^1)induce damages.Membranal lipid peroxidation(malondialdehyde,MDA formation(and glutamic pyruvic transaminase(GPT) release from the hepatocytes were markedly decreased.The damage of the cell surfaces of the hepatocytes were also reduced as seen under a scanning electrom microscope(SEM). Pretreatment with DDB(300mg·kg^-1)orally ameliorated the reduction of liver glycogen and blood glucose caused by ip injection of D-galactosamine(800mg·kg^-1)in mice.When normal rats were given DDB 300mg·kg^-1 once daily for 10d,the free ribosomal protein and RNA in the liver increased significantly.These results indicate that DDB is of beneficial effects on both damaged and normal hepatocytes. | FU TIEBO AND LIU GENGTAODepartment of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050,ChinaFox Chase Cancer Center. 7701 Burholme Avenue. Philadelphia, Pennsylvania 19111, USA.To whom correspondence should be addressed. | 1992 | Biomedical and Environmental Sciences1992，5，3： | 2 |
| 10 | Stroke gets in your eyes: stroke-induced retinal ischemia and the potential of stem cell therapy显示文摘Stroke persists as a global health and economic crisis,yet only two interventions to reduce stroke-induced brain injury exist.In the clinic,many patients who experience an ischemic stroke often further suffer from retinal ischemia,which can inhibit their ability to make a functional recovery and may diminish their overall quality of life.Despite this,no treatments for retinal ischemia have been developed.In both cases,ischemia-induced mitochondrial dysfunction initiates a cell loss cascade and inhibits endogenous brain repair.Stem cells have the ability to transfer healthy and functional mitochondria not only ischemic neurons,but also to similarly endangered retinal cells,replacing their defective mitochondria and thereby reducing cell death.In this review,we encapsulate and assess the relationship between cerebral and retinal ischemia,recent preclinical advancements made using in vitro and in vivo retinal ischemia models,the role of mitochondrial dysfunction in retinal ischemia pathology,and the therapeutic potential of stem cell-mediated mitochondrial transfer.Furthermore,we discuss the pitfalls in classic rodent functional assessments and the potential advantages of laser Doppler as a metric of stroke progression.The studies evaluated in this review highlight stem cell-derived mitochondrial transfer as a novel therapeutic approach to both retinal ischemia and stroke.Furthermore,we posit the immense correlation between cerebral and retinal ischemia as an underserved area of study,warranting exploration with the aim of these treating injuries together. | Chase Kingsbury Matt Heyck Brooke Bonsack Jea-Young Lee Cesar V.Borlongan | 2020 | Neural Regeneration Research2020，15，6： | 2 |
| 11 | Evaluation of National Research Council and Cornell Net Carbohydrate and Protein Systems for Predicting Requirements of Holstein Heifers显示文摘 | M.E. Van Amburgh D.G. Fox D.M. Galton D.E. Bauman L.E. Chase | 1998 | Journal of Dairy Science1998，，2： | 2 |
| 12 | Exploring ancestral phenotypes and evolutionary development of the mammalian middle ear based on Early Cretaceous Jehol mammals显示文摘We report a new Cretaceous multituberculate mammal with 3 D auditory bones preserved.Along with other fossil and extant mammals,the unequivocal auditory bones display features potentially representing ancestral phenotypes of the mammalian middle ear.These phenotypes show that the ectotympanic and the malleus-incus complex changed notably during their retreating from the dentary at various evolutionary stages and suggest convergent evolution of some features to extant mammals.In contrast,the incudomalleolar joint was conservative in having a braced hinge configuration,which narrows the morphological gap between the quadroarticular jaw joint of non-mammalian cynodonts and the incudomalleolar articulations of extant mammals.The saddle-shaped and abutting malleus-incus complexes in therians and monotremes,respectively,could have evolved from the braced hinge joint independently.The evolutionary changes recorded in the Mesozoic mammals are largely consistent with the middle ear morphogenesis during the ontogeny of extant mammals,supporting the relation between evolution and development. | Fangyuan Mao Cunyu Liu Morgan Hill Chase Andrew KSmith Jin Meng | 2021 | National Science Review2021，8，5： | 2 |
| 13 | Inflatable rock bolt bond strength versus rock mass rating (RMR): A comparative analysis of pull-out testing data from underground mines in Nevada显示文摘The purpose of this paper is to establish confidence in anticipated minimum bond strength for inflatable rock bolts by comparing the bond strength to variable geotechnical conditions using the rock mass rating(RMR) system. To investigate a correlation between these parameters,the minimum bond strength of pull-out tested inflatable rock bolts was compared to the RMR of the rock in which these bolts were placed. Bond strength vs. RMR plots indicate that expected minimum bond strength is positively correlated with RMR; however,the correlation is not strong. Cumulative percent graphs indicate that 97% of pull-out tests result in a minimum bond strength of 3.3 and 1.7 ton/m in RMR P 45 and <45,respectively.Although lower bond strengths are more commonly encountered in low RMR ground,high bond strengths are possible as well,yielding higher variability in bond strengths in low RMR ground. Bond strength of friction bolts relies on contact between the rock bolt and drill hole. Experience in Nevada indicates that RMR is known to affect both the quality and consistency of drill holes which likely affects bond strength. Drilling and bolting in low RMR ground is more sensitive to drilling and bolting practices,and strategies for maximizing bond strength in these conditions are discussed. | Barnard Chase Kallu Raj R. Warren Sean Thareja Rahul | 2016 | International Journal of Mining Science and Technology2016，26，1： | 2 |
| 14 | Antecedents of organizational slack 显示文摘 | Sharman M P Wolf G Chase R B | 1988 | Academy of Management Review1988，13，4： | 1 |
| 15 | 显示文摘 | Nash D C Chase H A | 1997 | J Chromatogr A1997，776，： | 1 |
| 16 | Metabolism of phenanthrene by the marine cyanobacterium Agmenellum quadruplicatum PR-6 显示文摘 | Martha L N Carl E C Chase V B | 1992 | Applied and Environment Microbiology1992，58，4： | 1 |
| 17 | Induction of heat shock proteins and motor function deficits after focal cerebellar injury显示文摘 | Allen G V Chase T | 2001 | Neuroscience2001，102，3： | 1 |
| 18 | Characterization and evaluation of a macroporous adsorbent for possible use in the expanded bed adsorption of flavonoids from Ginkgo biloba L 显示文摘 | Li J Chase H A | 2009 | J Chromatogr A2009，1216，50： | 1 |
| 19 | A proposal for a standardised protocol to barcode all land plants显示文摘 | Chase M W Cowan R S Hollingsworth P M | 2007 | Taxon2007，56，： | 1 |
| 20 | Fusion of ETV6 to the caudal-related homeobox gene CDX2 in acute myeloid leukemia with thet(12:13)(p13:q12)显示文摘 | Chase A Reiter A Burci L | 1999 | Blood1999，93，3： | 1 |
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