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| 1 | Circulating MicroRNA-208b and MicroRNA-499 Reflect Myocardial Damage in Cardiovascular Disease显示文摘 | Maarten F. Corsten Robert Dennert Sylvia Jochems Tatiana Kuznetsova Yvan Devaux Leon Hofstra Daniel R. Wagner Jan A. Staessen Stephane Heymans Blanche Schroen | 2010 | Circulation: Cardiovascular Genetics2010，，6： | 2 |
| 2 | miR-133 and miR-30 Regulate Connective Tissue Growth Factor: Implications for a Role of MicroRNAs in Myocardial Matrix Remodeling显示文摘 | Rudy F. Duisters Anke J. Tijsen Blanche Schroen Joost J. Leenders Viola Lentink Ingeborg van der Made Veronica Herias Rick E. van Leeuwen Mark W. Schellings Paul Barenbrug Jos G. Maessen Stephane Heymans Yigal M. Pinto Esther E. Creemers | 2009 | Circulation Research2009，，： | 2 |
| 3 | Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity显示文摘Dear Editor,Next-generation sequencing revealed that the majority of the human genome is transcribed but has no coding function.It is estimated that.30000 long noncoding RNAs(lncRNAs)are expressed in humans,but their functions are largely unknown(Suckau et al.,2009;Rinn and Chang,2012;Poller et al.,2013).Consideration of noncoding genomic elements in pathogenetic studies is warranted and enabled by technological advances allowing comprehensive transcriptome mapping of protein-coding genes as well as small and long ncRNAs. | Martina Gast Blanche Schroen Antje Voigt Jan Haas Uwe Kuehl Dirk Lassner Carsten Skurk Felicitas Escher Xiaomin Wang Adelheid Kratzer Katharina Michalik Anna Papageorgiou Tim Peters Madlen Loebel Sabrina Wilk Nadine Althof Kannanganattu VPrasanth Hugo Katus Benjamin Meder Shinichi Nakagawa Carmen Scheibenbogen Heinz-Peter Schultheiss Ulf Landmesser Stefanie Dimmeler Stephane Heymans Wolfgang Poller | 2016 | Journal of Molecular Cell Biology2016，8，2： | 2 |
| 4 | Inhibition of Urokinase-Type Plasminogen Activator or Matrix Metalloproteinases Prevents Cardiac Injury and Dysfunction During Viral Myocarditis显示文摘 | Stephane Heymans Matthias Pauschinger Armando De Palma Angela Kallwellis-Opara Susanne Rutschow Melissa Swinnen Davy Vanhoutte Fangye Gao Raimund Torpai Andrew H. Baker Elisabeth Padalko Johan Neyts Heinz-Peter Schultheiss Frans Van de Werf Peter Carmelie | 2006 | Circulation2006，，6： | 1 |
| 5 | Acute viral my- ocarditis显示文摘 | Robert Dennert Harry J Crijns Stephane Heymans | 2008 | Eur Heart J2008，29，17： | 1 |
| 6 | Integrating Cardiac PIP 3 and cAMP Signaling through a PKA Anchoring Function of p110γ显示文摘 | Alessia Perino Alessandra Ghigo Enrico Ferrero Fulvio Morello Gaetano Santulli George S. Baillie Federico Damilano Allan J. Dunlop Catherine Pawson Romy Walser Renzo Levi Fiorella Altruda Lorenzo Silengo Lorene K. Langeberg Gitte Neubauer Stephane Heymans | 2011 | Molecular Cell2011，，1： | 1 |
| 7 | Inflammation in viral myocarditis: friend or foe?显示文摘 | Maarten F. Corsten Blanche Schroen Stephane Heymans | 2012 | Trends in Molecular Medicine2012，，7： | 1 |
| 8 | Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy显示文摘 | Sudeshna Fisch Susan Gray Stephane Heymans | 2007 | Proc Natl Acad Sci2007，104，17： | 1 |
| 9 | MicroRNA‐18 and microRNA‐19 regulate CTGF and TSP‐1 expression in age‐related heart failure显示文摘 | Geert C. van Almen Wouter Verhesen Rick E. W. van Leeuwen Mathijs van de Vrie Casper Eurlings Mark W. M. Schellings Melissa Swinnen Jack P. M. Cleutjens Marc A. M. J. van Zandvoort Stephane Heymans Blanche Schroen | 2011 | Aging Cell2011，，5： | 1 |
| 10 | Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through pro-inflammatory effects and endothelial-mesenchymal transition显示文摘 | Colin E. Murdoch Sanjay Chaubey Lingfang Zeng Bin Yu Aleksander Ivetic Simon J. Walker Davy Vanhoutte Stephane Heymans David J. Grieve Alison C. Cave Alison C. Brewer Min Zhang Ajay M. Shah | 2014 | Journal of the American College of Cardiology2014，，： | 1 |
| 11 | MicroRNAs and Beyond: The Heart Reveals Its Treasures显示文摘 | Blanche Schroen Stephane Heymans | 2009 | Hypertension2009，，6： | 1 |
| 12 | Heart‘omicsin’AGEing (HOMAGE):design,research objectives and characteristics of the common database显示文摘Heart failure is common in older people and its prevalence is increasing.The Heart 'omics' in AGEing(HOMAGE) project aims to provide a biomarker approach that will improve the early diagnosis of heart failure.A large clinical database,based on(1) prospective population studies or(2) cross-sectional,prospective studies or randomized controlled trials(RCTs) of patients at risk for or with overt cardiovascular disease will be constructed to determine most promising 'omics'-based biomarkers to identify the risk of developing heart failure and/or comorbidities.Population studies,patient cohorts and RCTs are eligible for inclusion in the common database,if they received ethical approval to obtain and share data and have baseline information on cardiovascular risk factors.Currently,the HOMAGE database includes 43,065 subjects,from 20 studies in eight European countries,including healthy subjects from three population studies in France,Belgium and Italy(n = 7,124),patients with heart failure(n = 4,312) from four cohorts in the UK,Spain and Switzerland and patients at high risk for cardiovascular disease(n = 31,629) in 13 cohorts.It is anticipated that more partners will join the consortium and enlarge the pooled data.This large merged database will be a useful resource with which to identify candidate biomarkers that play a role in the mechanism underlying the onset and progression of heart failure. | Lotte Jacobs Lutgarde Thijs Yu Jin Faiez Zannad Alexandre Mebazaa Philippe Rouet Florence Pinet Christophe Bauters Burkert Pieske Andreas Tomaschitz Mamas Mamas Javier Diez Kenneth McDonald John G F Cleland Hans-Peter Brunner-La Rocca Stephane Heymans Roberto Latini Serge Masson Peter Sever Christian Delles Stuart Pocock Timothy Collier Tatiana Kuznetsova Jan A Staessen | 2014 | The Journal of Biomedical Research2014，28，5： | 1 |
| 13 | miR-133 and miR-30 Regulate Connective Tissue Growth Factor: Implications for a Role of MicroRNAs in Myocardial Matrix Remodeling显示文摘 | Rudy F. Duisters Anke J. Tijsen Blanche Schroen Joost J. Leenders Viola Lentink Ingeborg van der Made Veronica Herias Rick E. van Leeuwen Mark W. Schellings Paul Barenbrug Jos G. Maessen Stephane Heymans Yigal M. Pinto Esther E. Creemers | 2009 | Circulation Research2009，，2： | 1 |
| 14 | Macrophage microRNA 155 promotes cardiac hypertrophy and failure 显示文摘 | STEPHANE HEYMANS MAARTEN F CORSTEN WOUT ER VERHESEN | 2013 | Circulation2013，128，： | 1 |
| 15 | TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family 显示文摘 | Davy Vanhoutte Stephane Heymans | 2010 | JMol Cell Cardiol2010，48，3： | 1 |
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