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| 1 | Long-term follow-up after complete ablation of Barrett's esophagus with argon plasma coagulation显示文摘AIM: To report the long-term outcome of patients after complete ablation of non-neoplastic Barrett's esophagus (BE) with respect to BE relapse and development of intraepithelial neoplasia or esophageal adenocarcinoma.METHODS: In 70 patients with histologically proven nonneoplastic BE, complete BE ablation was achieved by argon plasma coagulation (APC) and high-dose proton pump inhibitor therapy (120 mg omeprazole daily). Sixty-six patients (94.4%) underwent further surveillance endoscopy. At each surveillance endoscopy four-quadrant biopsies were taken from the neo-squamous epithelium at 2 cm intervals depending on the pre-treatment length of BE mucosa beginning at the neo-Z-line, and from any endoscopically suspicious lesion.RESULTS: The median follow-up of 66 patients was 51 mo (range 9-85 mo) giving a total of 280.5 patient years.A mean of 6 biopsies were taken during surveillance endoscopies. In 13 patients (19.7%) tongues or islands suspicious for BE were found during endoscopy. In 8 of these patients (12.1%) non-neoplastic BE relapse was confirmed histologically giving a histological relapse rate of 3% per year. In none of the patients, intraepithelial neoplasia nor an esophageal adenocarcinoma was detected.Logistic regression analysis identified endoscopic detection of islands or tongues as the only positive predictor of BE relapse (P = 0.0004).CONCLUSION: The long-term relapse rate of nonneoplastic BE following complete ablation with high-power APC is low (3% per year). | Ahmed Madisch Stephan Miehike Ekkehard Bayerdoerffer Birgit Wiedemann David Antos Anke Sievert Michael Vieth Manfred Stolte Heinrich Schulz | 2005 | World Journal of Gastroenterology2005，11，8： | 14 |
| 2 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘 | Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote | 2012 | The Lancet2012，，： | 14 |
| 3 | 电工钢片磁性的计量问题显示文摘综述了电工钢片计量的当前水平和最新进展,重点讨论了在交变场中的标准测试方法:Epstein方圈法和单片(SST)法.所讨论的相关条款是有关磁通密度控制、数据获取和数据计算的最新电子方法,以及磁路设计对这两种方法的准确性和精度特性的影响,也讨论了系统误差来源、再现特性和经济因素等. | Johannes Sievert 刘亚丕 | 2008 | 中国计量学院学报2008，19，2： | 5 |
| 4 | STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation显示文摘 | Hazel Tye Catherine L. Kennedy Meri Najdovska Louise McLeod William McCormack Norman Hughes Anouk Dev William Sievert Chia Huey Ooi Tomo-o Ishikawa Hiroko Oshima Prithi S. Bhathal Andrew E. Parker Masanobu Oshima Patrick Tan Brendan J. Jenkins | 2012 | Cancer Cell2012，，4： | 3 |
| 5 | cytoplasmic domain of tissue factor promotes liver fibrosis in mice显示文摘AIM To evaluate the role of tissue factor(TF) and protease activated receptor(PAR)-2 in liver fibrosis.METHODS Using CCl4 administration for eight weeks, we induced hepatic fibrosis in wild-type C57BL/6 mice and in mice with deletion of the cytoplasmic signalling domain of TF(TF§CT/§CT), deletion of PAR-2(PAR-2-/-) and combined deletion of TF signalling domain and PAR-2(TF§CT/§CT/PAR-2-/-). Hepatic fibrosis area was assessed by quantitative imaging of picrosirius red staining. Hepatic collagen content was assessed by hydroxyproline levels. Hepatic stellate cells(αSMA positive) and hepatic macrophages(CD68 positive) were identified by immunohistochemistry. Hepatic gene expression was determined by PCR and liver TGFβ1 content by ELISA.RESULTS CCl4 treated mice with deletion of the PAR-2 gene(PAR-2-/-) and the cytoplasmic domain of TF(TF§CT/§CT) developed significantly less hepatic fibrosis, characterised by reduced liver fibrosis area and hydroxyproline content, compared to control wildtype mice treated with CCl4. The observed reduction in histological fibrosis was accompanied by a significant decrease in the hepatic content of TGFβ, the prototypic fibrogenic cytokine, as well as fewer activated hepatic stellate cells and hepatic macrophages. Deletion of the TF cytoplasmic signalling domain reduced hepatic fibrosis to levels similar to thoseobserved in mice lacking PAR-2 signalling but combined deletion provided no added protection against fibrosis indicating a lack of mutual modulating effects that have been observed in other contexts such as angiogenic responses.CONCLUSION Tissue factor cytoplasmic domain is involved in TF-PAR-2 signalling initiating hepatic fibrosis and is a potential therapeutic target, as its deletion would not impact coagulation. | Virginia Knight Dinushka Lourensz Jorge Tchongue Jeanne Correia Peter Tipping William Sievert | 2017 | World Journal of Gastroenterology2017，23，31： | 3 |
| 6 | 结构性心脏病介入治疗:现在和未来显示文摘结构性心脏病的概念及历史结构性心脏病是指任何心脏结构的异常、任何与心柱和大血管结构有关的疾病。广义的结街性心脏病是指除原发心电疾患和循环疾病以外,导致心脏结构的异常的疾病,即经超声心动图、核磁共振成像、运动负荷试验、心内膜活硷等现有的客观检查及尸体解剖能够发现的心脏结构异常。狭义的结构性心脏病是指解剖异常引起心脏结构的改变所造成心脏病理、生理的变化。 | Horst Sievert | 2015 | 中华医学信息导报2015，0，16： | 3 |
| 7 | Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing显示文摘 | Wendy S.C. Cheng Stuart K. Roberts Geoffrey McCaughan William Sievert Martin Weltman Darrell Crawford William Rawlinson Philippa S. Marks James Thommes Bishoy Rizkalla Motoko Yoshihara Gregory J Dore | 2010 | Journal of Hepatology2010，，4： | 2 |
| 8 | Percutaneous Left Atrial Appendage Transcatheter Occlusion to Prevent Stroke in High-Risk Patients With Atrial Fibrillation: Early Clinical Experience显示文摘 | Horst Sievert Michael D. Lesh Thomas Trepels Heyder Omran Antonio Bartorelli Paola Della Bella Toshiko Nakai Mark Reisman Carlo DiMario Peter Block Paul Kramer Dirk Fleschenberg Ulrike Krumsdorf Detlef Scherer | 2002 | Circulation: Journal of the American Heart Association2002，，16： | 2 |
| 9 | Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection显示文摘 | Matthew T. Kitson Gregory J. Dore Jacob George Peter Button Geoffrey W. McCaughan Darrell H.G. Crawford William Sievert Martin D. Weltman Wendy S. Cheng Stuart K. Roberts | 2012 | Journal of Hepatology2012，，： | 2 |
| 10 | IL 28 B genotype is not useful for predicting treatment outcome in A sian chronic hepatitis B patients treated with pegylated interferon‐α显示文摘 | Jacinta A Holmes Tin Nguyen Dilip Ratnam Neel M Heerasing Jane V Tehan Sara Bonanzinga Anouk Dev Sally Bell Stephen Pianko Robert Chen Kumar Visvanathan Rachel Hammond David Iser Ferry Rusli William Sievert Paul V Desmond D Scott Bowden Alexander J Thomps | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 11 | Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study显示文摘 | Henry Krum Markus Schlaich Rob Whitbourn Paul A Sobotka Jerzy Sadowski Krzysztof Bartus Boguslaw Kapelak Anthony Walton Horst Sievert Suku Thambar William T Abraham Murray Esler | 2009 | The Lancet2009，，9671： | 2 |
| 12 | Efficacy of Entecavir With or Without Tenofovir Disoproxil Fumarate for Nucleos(t)ide-Na?ve Patients With Chronic Hepatitis B显示文摘 | Anna S. Lok Huy Trinh Giampiero Carosi Ulus S. Akarca Adrian Gadano Fran?ois Habersetzer William Sievert David Wong Meghan Lovegren David Cohen Cyril Llamoso | 2012 | Gastroenterology2012，，3： | 2 |
| 13 | Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study显示文摘 | Henry Krum Markus Schlaich Rob Whitbourn Paul A Sobotka Jerzy Sadowski Krzysztof Bartus Boguslaw Kapelak Anthony Walton Horst Sievert Suku Thambar William T Abraham Murray Esler | 2009 | The Lancet . 2009 (9671)2009，，9671： | 2 |
| 14 | Staphylococcus aureus resistant to vancomyein-United States, 2002显示文摘 | Sievert DM Boulton ML Stoltman G | 2002 | MMWR2002，51，26： | 1 |
| 15 | Homologous acellular matrix graft for vaginal repair in rats:a pilot study for a new reconstruc- tive approach显示文摘 | Wefer J Sekido N Sievert KD | 2002 | World J Urol2002，20，： | 1 |
| 16 | Determination of magnetic power loss of e lectrical steel sheet: present status and trends显示文摘 | SIEVERT J D | 1984 | IEEE Trans Magn1984，20，： | 1 |
| 17 | Transeatheter closure of Atrial septal defeet and patenth foramen ovale with ASDOS device (a multi-institutional European trial)显示文摘 | Sievert H Baltic UU Haysdof G et a1 | | 0，，： | 1 |
| 18 | A novel approach to treat re- sidual peridevice leakage after left-atrial appendage closure 显示文摘 | Wunderlich N Wilson N Sievert H | 2013 | Catheter Cardiovasc Interv2013，82，： | 1 |
| 19 | Organ-specific acellular matrix for reconstruction of the urinary tract显示文摘 | Karl-Dietrich Sievert Emil A. Tanagho | 2000 | World Journal of Urology2000，，1： | 1 |
| 20 | Antimicrobial-re- sistant pathogens associated with healthcare-associated infec- tions: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Preven- tion, 2009- 2010显示文摘 | Sievert DM Ricks P Edwards JR | 2013 | Infect Control Hosp Epidemiol2013，34，1： | 1 |
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