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| 1 | Euglycemic diabetic ketoacidosis:A missed diagnosis显示文摘Euglycemic diabetic ketoacidosis(DKA)is an acute life-threatening metabolic emergency characterized by ketoacidosis and relatively lower blood glucose(less than 11 mmol/L).The absence of hyperglycemia is a conundrum for physicians in the emergency department and intensive care units;it may delay diagnosis and treatment causing worse outcomes.Euglycemic DKA is an uncommon diagnosis but can occur in patients with type 1 or type 2 diabetes mellitus.With the addition of sodium/glucose cotransporter-2 inhibitors in diabetes mellitus management,euglycemic DKA incidence has increased.The other causes of euglycemic DKA include pregnancy,fasting,bariatric surgery,gastroparesis,insulin pump failure,cocaine intoxication,chronic liver disease and glycogen storage disease.The pathophysiology of euglycemic DKA involves a relative or absolute carbohydrate deficit,milder degree of insulin deficiency or resistance and increased glucagon/insulin ratio.Euglycemic DKA is a diagnosis of exclusion and should be considered in the differential diagnosis of a sick patient with a history of diabetes mellitus despite lower blood glucose or absent urine ketones.The diagnostic workup includes arterial blood gas for metabolic acidosis,serum ketones and exclusion of other causes of high anion gap metabolic acidosis.Euglycemic DKA treatment is on the same principles as for DKA with correction of dehydration,electrolytes deficit and insulin replacement.The dextrosecontaining fluids should accompany intravenous insulin to correct metabolic acidosis,ketonemia and to avoid hypoglycemia. | Prashant Nasa Sandeep Chaudhary Pavan Kumar Shrivastava Aanchal Singh | 2021 | World Journal of Diabetes2021，12，5： | 11 |
| 2 | Nonunion of coronal shear fracture of femoral condyle显示文摘大腿骨的髁的孤立的花冠破裂在成年人是稀罕的并且 Hoffa 骨折不属于工会被报导仅仅在文学的一些时间。我们分析了六个案例在三年的一个时期上的 Hoffa 破裂不属于工会。三个病人保存地被对待,三个病人有固定失败。表示的延期是到一年的 2 个月。治疗协议与膝 arthrolysis 一起由开的减小, pseudoarthrosis 的切除,骨头 grafting 和内部固定组成了。联合在平均数 16 星期在所有病人被完成。治疗 Hoffa 破裂不属于工会要求小心的外科手术前的计划和过细的外科的技术。关于在破裂管理和外科的技术的争吵的文学被考察。 | Ajay Pal Singh Ish Kumar Dhammi Raju Vaishya Anil Kumar Jain Arun Pal Singh Prashant Modi | 2011 | Chinese Journal of Traumatology2011，14，3： | 11 |
| 3 | Current Status of Conventional and Molecular Interventions for Blast Resistance in Rice显示文摘Pyricularia oryzae anamorph of Magnaporthe oryzae is one of the most notorious fungal pathogens causing severe economic loss in rice production worldwide. Various methods, viz. cultural, biological and molecular approaches, are utilized to counteract this pathogen. Moreover, some tolerant or resistant rice varieties have been developed with the help of breeding programmes. Isolation and molecular characterization of different blast resistance genes now open the gate for new possibilities to elucidate the actual allelic variants of these genes via various molecular breeding and transgenic approaches. However, the behavioral pattern of this fungus breakups the resistance barriers in the resistant or tolerant rice varieties. This host-pathogen barrier will be possibly countered in future research by comparative genomics data from available genome sequence data of rice and M. oryzae for durable resistance. Present review emphasized fascinating recent updates, new molecular breeding approaches, transgenic and genomics approaches(i.e. mi RNA and genome editing) for the management of blast disease in rice. The updated information will be helpful for the durable, resistance breeding programme in rice against blast pathogen. | Deepti SRIVASTAVA Md SHAMIM Mahesh KUMAR Anurag MISHRA Pramila PANDEY Deepak KUMAR Prashant YADAV Mohammed Harrish SIDDIQUI Kapildeo Narayan SINGH | 2017 | Rice science2017，24，6： | 8 |
| 4 | Monteggia fracture dislocation equivalents analysis of eighteen cases treated by open reduction and internal fixation显示文摘 | Ajay Pal Singh Ish Kumar Dhammi Anil Kumar Jain Rajeev Raman Prashant Modi | 2011 | Chinese Journal of Traumatology2011，14，4： | 4 |
| 5 | Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats显示文摘Diabetic neuropathies are a family of nerve disorders caused by diabetes.Symptoms of the disease include nerve palsy,mononeuropathy,mononeuropathy multiplex,diabetic amyotrophy,painful polyneuropathy,autonomic neuropathy,and thoracoabdominal neuropathy.In this study,type 2 diabetes in rats was induced with nicotinamidestreptozotocin.Drug treatment was initiated on the d 15,with the combination regimen of metformin,pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin,amitriptyline and sitagliptin and led to significantly improved glycemic control,increased grip strength and paw jumping response on d 21,28 and 35(P < 0.001).Significant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21,28 and 35(P < 0.001).Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells,while administration of metformin and sitagliptin showed tissue regeneration and no body weight gain.In conclusion,treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain,but causes an increase in grip strength and pain sensitivity,exhibits neural protection,and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes. | Ashish Kumar Sharma Akash Sharma Rita Kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant Kumar Dhakad Davender Singh Kanawat Akanksha Mishra Anil Sharma Dharmendra Singh Ravinder Pal Singh Himmat Singh Chawda Rambir Singh Sachin Kumar Raikwar Muneem Kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam | 2012 | The Journal of Biomedical Research2012，26，3： | 2 |
| 6 | Safety assessment of Zanthoxylum alatum Roxb. essential oil, its antifungal, antiaflatoxin, antioxidant activity and efficacy as antimicrobial in preservation of Piper nigrum L. fruits显示文摘 | Bhanu Prakash Priyanka Singh Prashant Kumar Mishra N.K. Dubey | 2011 | International Journal of Food Microbiology2011，，1： | 1 |
| 7 | Recombinant trehalose-6-phosphate phosphatase of Brugia malayi cross-reacts with human Wuchereria bancrofti immune sera and engenders a robust protective outcome in mice显示文摘 | Susheela Kushwaha Prashant Kumar Singh Jyoti Gupta Vishal Kumar Soni Shailja Misra-Bhattacharya | 2012 | Microbes and Infection2012，，14： | 1 |
| 8 | Glycemic Properties of Trichosanthes dioica Leaves显示文摘 | Prashant Kumar Rai Dolly Jaiswal Rakesh Kumar Singh Rajesh Kumar Gupta Geeta Watal | 2008 | Pharmaceutical Biology2008，，12： | 1 |
| 9 | Comparison between intranasal dexmedetomidine and intranasal ketamine as premedication for procedural sedation in children undergoing MRI: a double-blind, randomized, placebo-controlled trial显示文摘 | Prakhar Gyanesh Rudrashish Haldar Divya Srivastava Prashant Mohan Agrawal Akhilesh Kumar Tiwari P. K. Singh | 2014 | Journal of Anesthesia2014，，1： | 1 |
| 10 | Antidiabetic effect of Ficus bengalensis aerial roots in experimental animals显示文摘 | Rakesh Kumar Singh Shikha Mehta Dolly Jaiswal Prashant Kumar Rai Geeta Watal | 2009 | Journal of Ethnopharmacology2009，，： | 1 |
| 11 | Protective efficacy of piperine against Mycobacterium tuberculosis显示文摘 | Sandeep Sharma Nitin Pal Kalia Pankaj Suden Prashant Singh Chauhan Manoj Kumar Anshu Beulah Ram Anamika Khajuria Sarang Bani Inshad Ali Khan | 2014 | Tuberculosis2014，，： | 1 |
| 12 | A facile one-pot synthesis of thioethers using heteropoly acids 显示文摘 | Kumar Ajeet Singh Prashant Kumar Santosh | 2007 | Journal of Molecular Catalysis A2007，276，1： | 1 |
| 13 | Antidepressants: Current Strategies and Future Opportunities显示文摘 | Archana Uppal Anita Singh Prashant Gahtori Surajit Kumar Ghosh Mohammad Zaki Ahmad | 2010 | Current Pharmaceutical Design2010，，38： | 1 |
| 14 | Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons显示文摘 | Prashant Kumar Modi Narayana Komaravelli Neha Singh Pushkar Sharma | 2012 | Molecular Biology of the Cell2012，，18： | 1 |
| 15 | Determinants of maternity care serv- ices utilization among married adolescents in rural India显示文摘 | Prashant Kumar Singh | 2012 | Plos One2012，，7： | 1 |
| 16 | A facile one-pot synthesis of thioethers using heteropoly acids显示文摘 | Kumar Ajeet Singh Prashant Kumar Santosh | 2007 | Journal of Molecular CatalysisA2007，276，1： | 1 |
| 17 | Safety assessment of Zanthoxylum alatum Roxb. essential oil, its antifungal, antiaflatoxin, antioxidant activity and efficacy as antimicrobial in preservation of Piper nigrum L. fruits显示文摘 | Bhanu Prakash Priyanka Singh Prashant Kumar Mishra N.K. Dubey | 2011 | International Journal of Food Microbiology2011，，1： | 1 |
| 18 | Luminescence studies and formation mechanism of symmetrically dispersed ZnO quantum dots embedded in SiO 2 matrix显示文摘 | Prashant K. Sharma Ranu K. Dutta Manvendra Kumar Prashant K. Singh Avinash C. Pandey | 2009 | Journal of Luminescence2009，，6： | 1 |
| 19 | Appraisal of land use/land cover of mangrove forest ecosystem using support vector machine显示文摘 | Sudhir Kumar Singh Prashant Srivastava Manika Gupta etc | 2014 | Environmental Earth Sciences2014，，5： | 1 |
| 20 | Extracellular Vesicles and Their Significance in COVID-19显示文摘Over the last few years,there is huge scientific attention towards the research related to Extracellular Vesicles(EVs),because of their unique property of inter cellular communications and effective biological significance in diagnosis and therapy[1].Extracellular Vesicles are lipid bilayer membrane bound biological entity,which contains different bioactive compounds(cargoes)such as microRNAs(miRNAs),mRNAs,proteins,and lipids.Based on their origin and size,EVs have been categorized into three different types(a)Exosomes(40 nm-150 nm)are smallest EVs,which are synthesized by endocytic pathways in the cells and secreted in extracellular space through exocytosis process,(b)Microvesicles are secreted from direct budding off plasma membranes and their size varying from 50 nm to 1000 nm and,(c)Apoptotic bodies are formed during apoptotic cell death process and respectively larger in size>1000 nm[1-3].EVs have been identified using different markers,that includes tetraspanins proteins(CD9,CD63,CD81,and CD83),endosomal sorting complexes required for transport(TSG101,Alix),heat shock proteins(Hsp60,Hsp70,Hsp90),and Rab proteins(RAB27a/b)[1]. | Sanjay Kumar Soumi Sadhu Himanshu Narayan Singh Navneet Kumar Dubey Nikhil Kumar Prashant Kumar Tiwari Rajan Malhotra Himani Sharma | 2022 | Advances in Human Physiology Research2022，4，1： | 0 |
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