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| 1 | Role of Moringa oleifera in regulation of diabetes-induced oxidative stress显示文摘Objective:To evaluate the antioxidant activity of aqueous extract of Atoringa oleifeta M.oleifera) young leaves by in vivo as well as in vitro assays.Methods:In vitro study included estimation of total phenolic,total ilavonol,total flavonoid and total antioxidant power(FRAP assay).Tn addition, in vivo study was done with the identified most effective dose of 200 nig/kg of its lyophilized powder on normal and diabetic rats.Its effect on different oxidative free radical scavenging enzymes,viz,superoxide dismutase(SOD),catalase(CAT),glutathione-S-transferase(GST),lipid peroxide(LPO) contents were measured.Results:Significant increase in activities of SOD.CAT, GST while,a decrease in LPO content was observed.Whereas,total phenolic,flavonoid and ilavonol contents in the extract were found to be 120 mg/g of CAK,40.5 mg/g of QEK and 12.12 mg/g of QE,respectively.On the other hand.FRAP assay results of M.oleifera leaves was(85.00±5.00)μM of Fe^+/g of extract powder.Conclusions:The significant antioxidant activities of M.oleifera leaves from both in vivo as well as in vitro studies suggests that the regular intake of its leaves through diet can protect normal as well as diabetic patients against oxidative damage. | Dolly Jaiswal Prashant Kumar Rai Shikha Mehta Sanjukta Chatterji Surekha Shukla Devendra Kumar Rai Gaurav Sharma Bechan Sharma Shahidul khair Geeta Watal | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，6： | 11 |
| 2 | Optimum chemotherapy in the management of metastatic pancreatic cancer显示文摘Pancreatic cancer is one of the most devastating solid tumors,and it remains one of the most difficult to treat.The treatment of metastatic pancreatic cancer(MPC)is systemic,based on chemotherapy or best supportive care,depending on the performance status of the patient.Two chemotherapeutical regimens have produced substantial benefits in the treatment of MPC:gemcitabine in 1997;and FOLFIRIONOX in 2011.FOLFIRINOX improved the natural history of MPC,with overall survival(OS)of 11.1 mo.Nab-paclitaxel associated with gemcitabine is a newly approved regimen for MPC,with a median OS of 8.6 mo.Despite multiple trials,this targeted therapy was not efficient in the treatment of MPC.Many new molecules targeting the proliferation and survival pathways,immune response,oncofetal signaling and the epigenetic changes are currently undergoing phaseⅠandⅡtrials for the treatment of MPC,with many promising results. | Marwan Ghosn Hampig Raphael Kourie Fadi El Karak Colette Hanna Joelle Antoun Dolly Nasr | 2014 | World Journal of Gastroenterology2014，20，9： | 7 |
| 3 | Anal cancer treatment:Current status and future perspectives显示文摘Anal cancers(AC)are relatively rare tumors.Their incidence is increasing,particularly among men who have sex with other men due to widespread infection by human papilloma virus.The majority of anal cancers are squamous cell carcinomas,and they are treated according to stage.In local and locally advanced AC,concomitant chemoradiation therapy based on mitomycin C and 5-Fluorouracil(5-FU)is the current best treatment,while metastatic AC,chemotherapy with 5-FU and cisplatin remains the gold standard.There are no indications for induction or maintenance therapies in locally advanced tumors.Many novel strategies,such as targeted therapies,vaccination,immunotherapy and photodynamic therapy are in clinical trials for the treatment of AC,with promising results in some indications. | Marwan Ghosn Hampig Raphael Kourie Pamela Abdayem Joelle Antoun Dolly Nasr | 2015 | World Journal of Gastroenterology2015，21，8： | 4 |
| 4 | Immediate Changes in Intraocular Pressure after Laser Peripheral Iridotomy in Primary Angle-Closure Suspects显示文摘 | Yuzhen Jiang Dolly S. Chang Paul J. Foster Mingguang He Shengsong Huang Tin Aung David S. Friedman | 2012 | Ophthalmology2012，，2： | 2 |
| 5 | Optimum chemotherapy for the management of advanced biliary tract cancer显示文摘Biliary tract cancers(BTCs) are highly fatal malignancies, which are often diagnosed at an advanced stage and have relatively poor prognosis.The treatment of patients with advanced BTC is systemic, based on chemotherapy or best supportive care, depending on their performance status.Despite clinical trials studyingmany chemotherapeutic regimens and targeted therapies for the treatment of BTC, the standard of care for advanced BTC remains the combination of gemcitabine with cisplatin.Many new molecules targeting proliferation and survival pathways, the immune response and angiogenesis are currently undergoing phase Ⅰ and Ⅱ trials for the treatment of advanced BTC with promising results. | Marwan Ghosn Hampig Raphael Kourie Elie El Rassy Ralph Chebib Fadi El Karak Colette Hanna Dolly Nasr | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 6 | Where does chemotherapy stands in the treatment of ampullary carcinoma? A review of literature显示文摘Ampullary carcinoma(AC) is a rare gastrointestinal tumor without clear treatment recommendations.The management of this tumor is usually extrapolated from the treatment of pancreatic,biliary duct and intestinal cancers.Few papers have studied the AC as an independent entity and yet succombs to several limitations.These studies were retrospective single institutional experiences with limited sample sizes recruited over a long period of time.Unlike metastatic ACs where chemotherapy is the only recommended option,localized AC once excised may be approached by either chemotherapy alone or concomitant chemoradiation therapy.In this review,we report the overall survival and recurrence factors of more than 1000 patients from all the studies treating exclusively ACs.We also review the medical treatment of this tumor and conclude to the necessity of multi-institutional randomized controlled studies for AC exclusively. | Marwan Ghosn Hampig Raphael Kourie Elie El Rassy Fady Ghassan Haddad Colette Hanna Fadi El Karak Dolly Nasr | 2016 | World Journal of Gastrointestinal Oncology2016，8，10： | 2 |
| 7 | Corporate hedging and the cost of debt 显示文摘 | Jun Chen Tao-Hsien Dolly King | 2014 | Journal of Corporate Finance2014，29，3： | 1 |
| 8 | Risk factors for pulmonary tuberculosis a clinic-based case control study in The Gambia 显示文摘 | Philip C Hill Dolly Jackson-Sillah Slmon A Donkor | 2006 | BMC Public Health2006，6，： | 1 |
| 9 | The impact of a three-factor pre- thrombin complex concentrate on the anticoagulatory effects of the factor Xa in- hibitor edoxaban显示文摘 | Brown KS Wickremasingha P Dolly A | 2015 | Thromb Res2015，136，4： | 1 |
| 10 | Knowledge And Practices Among Medical AbortionSeekers In Southeastern Nigeria显示文摘 | Echendu Dolly Adinma Joseph Ifeanyi Brian-D Adinma Chima Iw-uoha | 2012 | The Southeast Asian journal oftropical medicine and public health2012，43，2： | 1 |
| 11 | Creating a Low-anx(ety Classroom Environment: What Does Language Anxiety R, esearch Sugget?显示文摘 | Young Dolly J | 1991 | The Modern Language Journal1991，，： | 1 |
| 12 | Treatment options for small cell lung cancer--Do we have more choice? 显示文摘 | Puglisi M Dolly S Faria A | 2010 | Br J Cancer2010，102，4： | 1 |
| 13 | The structure and mode of action of different botulinum toxins显示文摘 | Dolly JO Aoki KR | 2006 | Eur J Neurol2006，13，4： | 1 |
| 14 | The Electronic Self-Help Provisions of UCITA:A Virtual Repo Man?显示文摘 | | 2000 | The John Marshall Law Review2000，，33： | 1 |
| 15 | Excitatory cholinergic and purinergic signaling in bladder are equally susceptible to botulinum neurotoxin A consistent with co-release of transmitters from efferent fibers显示文摘 | LAWRENCE GW AOKI KR DOLLY JO | 2010 | J Pharmacol Exp Ther2010，334，3： | 1 |
| 16 | Language Anxiety from the Foreign Language Specialist’s Perspective:Interviews with Krashen,Omaggio Hadley,Terrel and Rardin显示文摘 | Young Dolly J | 1992 | Foreign Language Annals1992，，25： | 1 |
| 17 | Crouzel,An improvement of acetate synthesis-non-radioactive contaminants by irradiation-induced species emanating from the carbon dioxide production target显示文摘 | Roeda F Dollie C | 2002 | Applied Radiation and Isotopes2002，57，： | 1 |
| 18 | Glycemic Properties of Trichosanthes dioica Leaves显示文摘 | Prashant Kumar Rai Dolly Jaiswal Rakesh Kumar Singh Rajesh Kumar Gupta Geeta Watal | 2008 | Pharmaceutical Biology2008，，12： | 1 |
| 19 | Is Dividend Policy related to Information Asymmetry Evidence from Insider Trading Gains显示文摘 | Kenneth Khang and Dolly King | 2002 | Working paper2002，4，： | 1 |
| 20 | Microencapsulation of Lactobacillus plantarum (mtcc 5422) by spray-freeze-drying method and evaluation of survival in simulated gastrointestinal conditions显示文摘 | Dolly P Anishaparvin A Joseph G S | 2011 | J Microencapsul2011，28，6： | 1 |
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