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    题名 作者 年代 出处 被引量
1亚麻籽环肽混合物抑制霉菌生长繁殖活性显示文摘选取宛氏拟青霉(AS 3.776)和黄曲霉(CICC 2476)作为试验菌株,于121℃高温灭菌前、后添加一定浓度梯度的亚麻籽环肽混合物(flaxseed cyclolinopeptides,FCLPs)到马铃薯葡萄糖琼脂培养基中。FCLPs对宛氏拟青霉孢子形成的半数抑制浓度IC50分别为0.53 mg/m L(高温灭菌)和0.34 mg/m L(未经高温灭菌);对黄曲霉孢子形成的IC50值分别为0.31 mg/m L(高温灭菌)和0.24 mg/m L(未经高温灭菌)。高温灭菌处理后,FCLPs保持了相当的抑菌活性,对宛氏拟青霉的抑制活性最低残留76.8%(菌落生长)和76.7%(孢子形成);对于黄曲霉的抑制活性,最低残留分别为61.6%(菌落生长)和41.7%(孢子形成)。FCLPs对孢子萌发率的平均抑制率为17.8%(宛氏拟青霉)和7.8%(黄曲霉)。采用高效液相色谱法分析霉菌培养后从培养基中提取的FCLPs,发现高温灭菌会降低环肽的含量,这可能是导致环肽抗菌活性下降的原因之一,但环肽中4种主要环肽的比例没有发生明显变化,且没有发现环肽霉菌代谢物产生。综上所述,FCLPs对霉菌具有一定抑制活性,对高温处理较为稳定,能耐食品的热加工,相比现有抗菌肽具有独特优势。刘尊 汪勇 MARTIN J T REANEY FIORENTY OCTAVIA SUGIWAN NANDA AYU YULISTYANITA 张宁 2018食品与发酵工业2018,44,3:11
2Nonalcoholic steatohepatitis in Asian Indians is neither associated with iron overload nor with HFE gene mutations显示文摘AIM: The pathogenesis of occurrence of liver inflammation and fibrosis in patients with nonalcoholic steatohepatitis (NASH) is not completely understood. Other than insulin resistance, iron abnormalities have been thought to be one of the triggering factors. Therefore, our aim was to study the role of iron abnormalities and HFE gene mutations in patients with NASH.METHODS: Thirty-one patients of NASH diagnosed on the basis of clinical examination biochemistry, ultrasonography and liver biopsy (n = 14) were included in the study. Serum iron parameters (n = 23) (iron, ferritin, total iron-binding capacity and transferrin saturation), Peris' iron staining on liver biopsies (n = 14) and HFE gene mutations (C282Y and H63D) (n = 16) were studied in these patients. The association between iron staining, necroinflammatory activity and fibrosis stage on liver biopsies was also determined.RESULTS: Elevated serum iron, ferritin and transferrin saturation above 55% were observed in 4.3% of patients.On histology, 71% of the patients had negative iron staining,21.4% had 1+ staining, 7.2% had 2+ staining and none had 3+ or 4+ staining. There was no association between the degree of iron staining and necroinflammatory activity (P = 0.55) and fibrosis stage (P = 0.09) on histology. None of the patients had C282Y HFE gene mutation and four patients (25%) were found to be heterozygotes for H63D gene mutation.CONCLUSION: Our study does not favor iron overload and HFE gene mutations as major factors in the pathogenesis of NASH in Asian Indians.Ajay Duseja Reena Das Mohit Nanda Ashim Das Gurjeewan Garewal Yogesh Chawla 2005World Journal of Gastroenterology2005,11,3:9
3Earnings management and investor protection: an international comparison显示文摘Christian Leuz Dhananjay Nanda Peter D Wysocki 2003Journal of Financial Economics2003,,3:5
4合成B_(4)C和天然钛铁矿陶瓷颗粒增强LM13铝硅合金基复合材料的磨损性能对比显示文摘研究以LM13铝硅合金为基体、陶瓷颗粒为增强相,采用搅拌铸造法制备的复合材料(AMCs)的干滑动磨损行为。分别采用两种不同的陶瓷颗粒增强相:合成的B_(4)C和天然的钛铁矿陶瓷颗粒。光学显微镜结果显示,增强颗粒均匀分散在基体材料中,增强颗粒使共晶硅的晶粒尺寸细化,形貌变为球形。B_(4)C增强复合材料(BRCs)的硬度提高最大,而钛铁矿增强复合材料(IRCs)由于界面化合物的形成导致基体−增强相界面结合较强,摩擦因数降低最大。与基体合金相比,复合材料的干滑动磨损性能显著提高。B_(4)C颗粒的低密度和高硬度导致BRCs中颗粒周围高的位错密度。另一方面,钛铁矿颗粒的低热导率导致IRCs表面发生早期氧化并形成摩擦层。可见,尽管两种类型的增强相的作用机制存在很大不同,他们都能改善AMCs的耐磨性能。因此,低成本钛铁矿颗粒可替代高成本B_(4)C颗粒,制备耐磨复合材料。Rahul GUPTA Tarun NANDA O.P.PANDEY 2021Transactions of Nonferrous Metals Society of China2021,31,12:5
5Review of imaging and endovascular intervention of iliocaval venous compression syndrome显示文摘Iliocaval venous compression syndrome(ICS)is the extrinsic compression of the common iliac vein by the overlying iliac artery against the vertebra.Chronic compression can lead to venous stenosis and stasis,which manifests as chronic venous disease and treatment resistance.Therefore,early recognition of ICS and prompt treatment are essential.Clinical presentations of ICS can be ambiguous and diagnosis requires a high index of suspicion with the relevant imaging studies.The initial imaging test is typically a Duplex ultrasound for vessel assessment and pelvic ultrasound to exclude a compressive mass,which is followed by computed tomography(CT)or magnetic resonance(MR)venography.CT and MRI can identify the anatomical causes for venous compression.In patients with high clinical suspicion for ICS,negative findings on CT and MR venography would still warrant further investigations.Definitive diagnosis can be established using catheter-based venography complemented with intravascular ultrasonography but the nature of their invasiveness limits its utility as a routine imaging modality.In this review paper,we will discuss the evidence,utility and limitations of the existing imaging modalities and endovascular intervention used in the management of ICS.Ming Ren Toh Tjun Yip Tang Han Hui Mervin Nathan Lim Nanda Venkatanarasimha Karthikeyan Damodharan 2020World Journal of Radiology2020,12,3:4
6Biomechanical testing of the locking compression plate: When does the distance between bone and implant significantly reduce construct stability?显示文摘M. Ahmad R. Nanda A.S. Bajwa J. Candal-Couto S. Green A.C. Hui 2007Injury2007,,3:4
7Incoherent Fourier ptychographic photography using structured light显示文摘Controlling photographic illumination in a structured fashion is a common practice in computational photography and image-based rendering. Here we introduce an incoherent photographic imaging approach, termed Fourier ptychographic photography, that uses nonuniform structured light for super-resolution imaging. In this approach,frequency mixing between the object and the structured light shifts the high-frequency object information to the passband of the photographic lens. Therefore, the recorded intensity images contain object information that is beyond the cutoff frequency of the collection optics. Based on multiple images acquired under different structured light patterns, we used the Fourier ptychographic algorithm to recover the super-resolution object image and the unknown illumination pattern. We demonstrated the reported approach by imaging various objects, including a resolution target, a quick response code, a dollar bill, an insect, and a color leaf. The reported approach may find applications in photographic imaging settings, remote sensing, and imaging radar. It may also provide new insights for high-resolution imaging by shifting the focus from the collection optics to the generation of structured light.Siyuan Dong Pariksheet Nanda Kaikai Guo Jun Liao Guoan Zheng 2015Photonics Research2015,3,1:4
8反相高效液相色谱法同时测定片剂中的加替沙星与盐酸氨溴索(英文)显示文摘A reversed-phase high performance liquid chromatography (HPLC) method was developed, validated, and used for the quantitative determination of gatifloxacin (GA) and ambroxol hydrochloride (AM), from its tablet dosage form. Chromatographic separation was performed on a HiQ Sil C18 column (250 mm×4.6 mm, 5 μm), with a mobile phase comprising of a mixture of 0.01 mol/L potassium dihydrogen orthophosphate buffer and acetonitrile (70∶30, v/v), and pH adjusted to 3 with orthophosphoric acid, at a flow rate of 1 mL/min, with detection at 247 nm. Separation was completed in less than 10 min. As per International Conference on Harmonisation (ICH) guidelines the method was validated for linearity, accuracy, precision, limit of quantitation, limit of detection, and robustness. Linearity of GA was found to be in the range of 10-60 μg/mL and that for AM was found to be 5-30 μg/mL. The correlation coefficients were 0.999 6 and 0.999 3 for GA and AM respectively. The results of the tablet analysis (n=5) were found to be 99.94% with ±0.25% standard deviation (SD) and 99.98% with±0.36% SD for GA and AM respectively. Percent recovery of GA was found to be 99.92%-100.02% and that of AM was 99.86%-100.16%. The assay experiment shows that the method is free from interference of excipients. This demonstrates that the developed HPLC method is simple, linear, precise, and accurate, and can be conveniently adopted for the routine quality control analysis of the tablet.SHAHED Mirza NANDA Rabindra DEHGHAN Muhammad Hassan NASREEN Huda FEROZ Shaikh 2008色谱2008,26,3:3
9A state-of-the-art review of solar passive building system for heating or cooling purpose显示文摘一座大楼里的精力的主要部分被加热消费,通气,并且空气调节(HVAC ) 。传统的加热并且冷却的系统极大地作出贡献到温室气体的排放,特别二氧化碳。四个不同方法,即, Trombe 墙,太阳的烟囱,无光的公开太阳的 fa ? 果汁饮料,和太阳的房顶,为太阳的加热被采用。同样,二主修方法,即,综合成为蒸气的冷却的成为蒸气的冷却并且造为大楼冷却被采用。因此,在这份报纸被尝试了编在一座大楼里的技术的太阳的加热并且冷却的开发。Arun Kumar NANDA C K PANIGRAHI 2016Frontiers in Energy2016,10,3:3
10High sustained virologic response rates in children with chronic hepatitis C receiving peginterferon alfa-2b plus ribavirin显示文摘Stefan Wirth Carmen Ribes-Koninckx Maria Angeles Calzado Flavia Bortolotti Lucia Zancan Paloma Jara Mark Shelton Nanda Kerkar Marcela Galoppo Alejandra Pedreira Norberto Rodriguez-Baez Mirta Ciocca Alain Lachaux Florence Lacaille Thomas Lang Ulrike Kullme 2010Journal of Hepatology2010,,4:2
11Optimization, equilibrium, adsorption behavior and role of surface functional groups on graphene oxide-based nanocomposite towards diclofenac drug显示文摘Aquatic contamination of diclofenac(DCF),an emergent non-steroidal anti-inflammatory drug(NSAIDs),can result in adverse effects to many ecosystems through biomagnification.Hence,introducing effective remediation techniques to sequester the pharmaceutical wastes is highly fundamental to prevent their accumulation in the environment.Generally,adsorption has been presented as a green and efficient approach.Herein,we report the characterization and application of the novel magnetic nanocomposite(GO@CoFe2O4)derived from cobalt-based ferrite(CoFe2O4)and graphene oxide(GO)for DCF adsorption.For the optimization procedure,the response surface methodology(RSM)was adopted to investigate the impacts of DCF concentration(1.6-18.4 mg/L),DCF dosage(0.08-0.92 g/L),and solution pH(2.6-9.4)to find the optimum conditions for DCF removal,at 10.5 mg/L,0.74 g/L,and pH 4,respectively.For the adsorption experiments,the kinetic,isotherm,thermodynamic,and intraparticle diffusion models were systematically studied.Moreover,we have elucidated the role of functional groups on the surface of GO@CoFe2O4 in enhancing the adsorption of DCF drug.With good removal efficiency(up to 86.1%),high maximum adsorption capacity(32.4 mg/g),GO@CoFe2O4 can be a potential candidate to eliminate DCF drug from water.Thuan Van Tran Duyen Thi Cam Nguyen Hanh TNLe Dai-Viet NVo Sonil Nanda Trinh Duy Nguyen 2020Journal of Environmental Sciences2020,32,7:2
12Association of vitamin D and knee osteoarthritis in younger individuals显示文摘BACKGROUND The incidence of primary osteoarthritis knee is gradually increasing among young individuals.The increasing prevalence of obesity,sedentary lifestyle,sporting activity,and vitamin D deficiency(VDD)has been hypothesized for this shifting disease trend.This study was designed to look for the association of serum vitamin D among these young arthritic patients.AIM To look for the association of serum vitamin D in younger knee osteoarthritis(KOA)patients.METHODS In a 2-year observational study,146 non-obese KOA patients of 35-60 years were evaluated clinically(Knee injury and Osteoarthritis Outcome Score,KOOS)and radiologically(Kellegren-Lawrence stage,KL).The serum 25(OH)D level of these patients and 146 normal healthy individuals of same age group were estimated.RESULTS Both the groups were comparable in terms of age and sex.The average serum 25(OH)D level in healthy individuals and KOA patients was 45.83 ng/mL and 34.58 ng/mL,respectively(P<0.001).Inadequate serum 25(OH)D level(<30 ng/mL)was found in 46.57%of KOA patients and 24%of normal healthy participants indicating a significant positive association(odds ratio 2.77,95%CI:1.67-4.54,P<0.001).The 25(OH)D level in KL grade I,II,III and IV was 43.40,30.59,31.56 and 33.93 ng/mL respectively(no difference,P=0.47).Similarly,the KOOS score in sufficient,insufficient and deficient groups were 65.31,60.36 and 65.31,respectively(no difference,P=0.051).CONCLUSION The serum 25(OH)D level is significantly low in younger KOA patients.However,the clinical and radiological severities have no association with serum vitamin D level.Sujit Kumar Tripathy Amrit Gantaguru Saurav Narayan Nanda Sandeep Velagada Anand Srinivasan Manaswini Mangaraj 2020World Journal of Orthopedics2020,11,10:2
13Liquidity, investment ability, and mutual fund structure显示文摘Nanda V Narayanan M P Warther V A 2000Journal of Financial Economics2000,57,:2
14Are Incentive Contracts Rigged by Powerful CEOs?显示文摘ADAIR MORSE VIKRAM NANDA AMIT SERU 2011The Journal of Finance2011,,5:2
15Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculatus显示文摘Mariko Kondo Alexander Froschauer Akiko Kitano Indrajit Nanda Ute Hornung Jean-Nicolas Volff Shuichi Asakawa Hiroshi Mitani Kiyoshi Naruse Minoru Tanaka Michael Schmid Nobuyoshi Shimizu Manfred Schartl Akihiro Shima 2002Gene2002,,2:2
16Democratizing entry: Banking deregulations, financing constraints, and entrepreneurship显示文摘William R. Kerr Ramana Nanda 2009Journal of Financial Economics2009,,1:2
17Short-term and long-term Interconnectedness of stock returns in Western Europe and the global market显示文摘Background:The present study examines the short term dynamics and long term equilibrium relationship among the stock markets of 17 countries in Western Europe as well as the world market,using time series techniques.Methods:Weekly returns of market benchmark indices of the respective countries are used from the second week of 1995 to the fourth week of December 2013.Results:The study finds that the market returns of Austria,Belgium,the Netherlands,and France are relatively less dynamically interlinked as compared with Britain,Denmark,Finland,Germany,Portugal,Spain,Sweden,Switzerland,Greece,Ireland,Luxembourg,and Norway,which are quite dynamically interlinked within the region as well as with the MSCI world index.Conclusion:There exists a strong long run equilibrium relationship between the return distributions of the stock markets within the region.Ajaya Kumar Panda Swagatika Nanda 2017Financial Innovation2017,3,1:2
18实时三维经胸超声心动图评价主动脉瓣狭窄的价值显示文摘目的评价实时三维经胸超声心动图(3D-TTE)测量主动脉瓣面积以评估主动脉瓣狭窄的价值。方法22例主动脉瓣狭窄患者,3D-TTE测量其主动脉瓣瓣口面积(3D-AVA)。以心导管法获得的主动脉瓣瓣口面积(Cath-AVA)作为金标准,连续方程计算主动脉瓣瓣口面积(Cont-AVA),计算多普勒测量的跨瓣最大血流速度(Vmax)和最大跨瓣压差(PGmax)、平均跨瓣压差(PGmean)、Cont-AVA、3D-AVA与Cath-AVA相互间的相关性。结果3D-AVA、Cont-AVA、Vmax、PGmax、PGmean与Cath-AVA的相关系数分别为0.93,0.76,0.61,0.54,0.57;Cont-AVA与Cath-AVA相关系数均为0.76。结论3D-AVA能准确评价主动脉瓣狭窄,与Cont-AVA和Cath-AVA检查结果无差异。方理刚 Navin C. Nanda 郭立琳 朱文玲 方全 2009临床超声医学杂志2009,11,3:2
19Two‐ and Three‐Dimensional Speckle Tracking Echocardiography: Clinical Applications and Future Directions显示文摘Monodeep Biswas Selvin Sudhakar Navin C. Nanda Gerald Buckberg Manish Pradhan Asad Ullah Roomi Willem Gorissen Helene Houle 2013Echocardiography2013,,1:2
20Experience with hemoadsorption (CytoSorb~?) in the management of septic shock patients显示文摘BACKGROUND Cytokines and inflammatory mediators are the hallmarks of sepsis.Extracorporeal cytokine hemoadsorption devices are the newer clinical support system to overcome the cytokine storm during sepsis.AIM To retrospectively evaluate the clinical outcomes of patients admitted in intensive care unit with septic shock with different etiologies.METHODS The laboratory parameters including biomarkers such as procalcitonin,serum lactate and C-reactive protein;and the hemodynamic parameters;mean arterial pressure,vasopressor doses,sepsis scores,cytokine levels and other vital parameters were evaluated.We evaluated these outcomes among survivors and non-survivors.RESULTS Of 100 patients evaluated,40 patients survived.Post treatment,the vasopressors dosage remarkably decreased though it was not statistically different;34.15%(P=0.0816)for epinephrine,20.5%for norepinephrine(P=0.3099)and 51%(P=0.0678)for vasopressin.In the survivor group,a remarkable reduction of biomarkers levels;procalcitonin(65%,P=0.5859),C-reactive protein(27%,P=0.659),serum lactate(27%,P=0.0159)and bilirubin(43.11%;P=0.0565)were observed from baseline after CytoSorb^® therapy.A significant reduction in inflammatory markers;interleukin 6 and interleukin 10;(87%and 92%,P<0.0001)and in tumour necrosis factor(24%,P=0.0003)was also seen.Overall,28(28%)patients who were given CytoSorb^® therapy less than 48 h after onset of septic shock survived and the maximum duration of stay for 70%of these patients in intensive care unit was less than 15 d.CONCLUSION CytoSorb^® is a safe and well tolerated rescue therapy option in patients with septic shock.However,early(preferably within<48 h after onset of septic shock)initiation could result in better clinical outcomes.Further randomized trials are needed to define the potential benefits of this new treatment modality.Yatin Mehta Chitra Mehta Ashish Kumar Joby Varghese George Aditi Gupta Saurabh Nanda Gourav Kochhar Arun Raizada 2020World Journal of Critical Care Medicine2020,9,1:2
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