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| 1 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017，9，1： | 2 |
| 2 | High sustained virologic response rates in children with chronic hepatitis C receiving peginterferon alfa-2b plus ribavirin显示文摘 | Stefan Wirth Carmen Ribes-Koninckx Maria Angeles Calzado Flavia Bortolotti Lucia Zancan Paloma Jara Mark Shelton Nanda Kerkar Marcela Galoppo Alejandra Pedreira Norberto Rodriguez-Baez Mirta Ciocca Alain Lachaux Florence Lacaille Thomas Lang Ulrike Kullme | 2010 | Journal of Hepatology2010，，4： | 2 |
| 3 | Extraction of a monospecific Coombs-reagent from chicken eggs 显示文摘 | Gutierrez Calzado E Cruz Mario E Samon Chavez T | 2003 | ALTEX2003，20，1： | 1 |
| 4 | Human haemoclassification by use of specific yolk antibodies obtained after immunization of chickens against human blood group antigens 显示文摘 | Calzado EG Garrido RMG Schade R | 2001 | ATLA2001，29，6： | 1 |
| 5 | Chicken egg yolk antibodies (IgY-technology):a review of progress in production and use in research and human and veterinary medicine显示文摘 | Schade R Calzado E G Sarmiento R | 2005 | Alternatives to Laboratory Animals2005，33，2： | 1 |
| 6 | Chicken egg yolk antibodies (IgY-technology): A review of progress in production and use in research and human and veterinary medicine显示文摘 | Schade R Calzado EG Sarmiento R | 2005 | Altern Lab Anim2005，33，2： | 1 |
| 7 | Chicken egg yolk antibodies (IgY-technology) : a review of progress in production and use in research and human and veterinary medicine 显示文摘 | Schade R Calzado EG Sarmiento R | 2005 | Ahem Lab Anita2005，33，2： | 1 |
| 8 | Phosphorylation-dependentcontrol of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2显示文摘 | Roscic A Moller A Calzado MA | 2006 | Mol Cell2006，24，1： | 1 |
| 9 | High sus- tained virologic response rates in children with chronic hepati- tis C receiving peginterferon alfa -2b plus ribavirin 显示文摘 | Wirth S Ribes -Koninckx C Calzado MA | 2010 | J Hepatol2010，52，4： | 1 |
| 10 | The5-HT3 receptor antag- onist tropisetron inhibits T cell activation by targeting the calcineur in pathway显示文摘 | Vega L L Munoz E Calzado M A | 2005 | Biochena Pharmacol2005，70，3： | 1 |
| 11 | Chicken egg yolk antibodies ( IgY-technology ) : a review of progress in production and use in research and human and veterinary medicine显示文摘 | Schade R Calzado EG Sarmiento R | 2005 | Altern Lab Anim2005，33，2： | 1 |
| 12 | Chicken egg yolk antibodies (IgY-technology) : a review of progress in production and use in research and human and veterinary medicine 显示文摘 | Schade R Calzado E G Sarmiento R | 2005 | A1- tern Lab Anita2005，33，2： | 1 |
| 13 | Low contrast detectability performance of model observers based on CT phantom images:kVp influence显示文摘 | Hernandez-Giron I Calzado A Geleijns J | 2015 | Phys Med2015，31，7： | 1 |
| 14 | Comparison between human and model observer performance in low-contrast detection tasks in CT images:application to images reconstructed with filtered back projection and iterative algorithms显示文摘 | Hernandez-Giron I Calzado A Geleijns J | 2014 | Br J Radiol2014，87，20： | 1 |
| 15 | Chicken egg yolk antibodies (IgY-technology): a review of progress in production and use in research and human and veterinarymedicine显示文摘 | Schade R Calzado EG Sarmiento R Chacana PA Porankiewicz-Asplund J Terzolo HR | 2005 | Altern Lab Anim2005，33，2： | 1 |
| 16 | High sustained virologic response rates in children with chronic hepatitis C receiving peginterferon alfa-2b plus ribavirin 显示文摘 | Wirth S Ribes-Koninckx C Calzado MA | 2010 | J Hepatol2010，52，4： | 1 |
| 17 | Nickel recoveredfrom solution by oxidation using ozone: some physicalproperties显示文摘 | CALZADO L E GOMEZ C O FINCH J A | 2005 | Mineral Engineering2005，18，： | 1 |
| 18 | NF-kappa B inhibitors for the treatment of inflammatory diseases and cancer显示文摘 | Calzado MA Bacher S Schmitz ML | | 0，，03： | 1 |
| 19 | Chicken egg yolk antibodies (IgY-technology):a review of prowess in production and use in research and human and veterinary medicine显示文摘 | Schade R Calzado E G Sarmiento R | 2005 | Alternatives to Laboratory Animals2005，33，： | 1 |
| 20 | Clinical out-come of hepatocyte transplantation in four pediatric patients with inherited metabolic diseases显示文摘 | Ribes-Koninckx C Ibars EP Calzado AA | | 0，，10： | 1 |
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