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| 1 | Malignant solitary fibrous tumor involving the liver显示文摘Solitary fibrous tumors are predominantly benign and are most commonly found in the thoracic cavity and pleura; while reports exist in the literature of malignant solitary fibrous tumors and those located in extrathoracic organs, these cases are considered extremely rare. Herein, a case is reported of a malignant solitary fibrous tumor involving the liver that was diagnosed and treated in a 62-year-old woman. The patient presented with complaints of upper abdominal pain and unintentional weight loss. Computed tomography scan of the abdomen revealed a remarkably large mass, measuring 15 cm × 10 cm × 20 cm, which appeared to be unrelated to any particular organ. The intraoperative finding of a wide communication with the left liver suggested hepatic origin, and served as an indicator for tumor resection via left hemihepatectomy. The diagnosis of solitary fibrous tumor and its malignant nature was confirmed by histological and immunohistochemical examination of the resected tissues. Hepatic solitary fibrous tumor is very rare, and surgery remains the mainstay of treatment. Due to limited reports of such tumors in the literature, little can be said about the benefit of adjuvant therapy and prognosis for the rare cases with malignant histological findings. | Manuel Jakob Matthias Schneider Ingo Hoeller Urban Laffer Reto Kaderli | 2013 | World Journal of Gastroenterology2013，19，21： | 7 |
| 2 | Effects of sleep bruxism on functional and occlusal parameters:a prospective controlled investigation显示文摘This study was conducted to verify the results of a preceding retrospective pilot study by means of a prospective controlled investigation including a larger sample size.Therefore,the aim of this clinical investigation was to analyze the relationship between sleep bruxism and several functional and occlusal parameters.The null hypothesis of this study was that there would be no differences among sleep bruxism subjects and non-sleep bruxism controls regarding several functional and occlusal parameters.Fifty-eight sleep bruxism subjects and 31 controls participated in this study.The diagnosis sleep bruxism was based on clinical criteria of the American Academy of Sleep Medicine.Sixteen functional and occlusal parameters were recorded clinically or from dental study casts.Similar to the recently published retrospective pilot study,with a mean slide of 0.77 mm(s.d.,0.69 mm) in the sleep bruxism group and a mean slide of 0.4 mm(s.d.,0.57 mm) in the control group,the evaluation of the mean comparison between the two groups demonstrated a larger slide from centric occlusion to maximum intercuspation in sleep bruxism subjects(Mann-Whitney U-test;P50.008).However,following Bonferroni adjustment,none of the 16 occlusal and functional variables differed significantly between the sleep bruxism subjects and the non-sleep bruxism controls.The present study shows that the occlusal and functional parameters evaluated do not differ between sleep bruxism subjects and non-sleep bruxism subjects.However,as the literature reveals a possible association between bruxism and certain subgroups of temporomandibular disorders,it appears advisable to incorporate the individual adaptive capacity of the stomatognathic system into future investigations. | Michelle Alicia Ommerborn Maria Giraki Christine Schneider Lars Michael Fuck Jrg Handschel Matthias Franz Wolfgang Hans-Michael Raab Ralf Schfer | 2012 | International Journal of Oral Science2012，4，3： | 4 |
| 3 | Colorectal cancer of the young displays distinct features of aggressive tumor biology:A single-center cohort study显示文摘BACKGROUND In recent years,a decrease in incidence and mortality of colorectal cancer(CRC)has been observed in developed nations,presumably through public disease awareness and increased screening efforts.However,a rising incidence of CRC in young patients below the age of 50 years has been reported in several studies.AIM To study tumor biology in CRC patients below 50 years of age.METHODS All patients with CRC were prospectively enrolled in our single-center oncologic database from January 2013 to December 2018 and were grouped and analyzed according to age(≥50 and<50 years).Clinical as well as histopathological features were analyzed and compared.The study was approved by the local Ethics Committee.Fisher’s exact test or t-test was used to test for differences between the groups,as appropriate.All statistical analysis was performed with IBM SPSS software Version 25(SPSS Inc,Armonk,NY,United States)and with RStudio using R Version 3.4.1(RStudio,Boston,MA,United States).RESULTS Seventeen percent of the 411 patients were younger than 50 years.Young patients were more often diagnosed with locally advanced T4-tumors and lymph node metastases(36.6%and 62%vs 17.7%and 42%;P<0.01).In addition,a higher frequency of poorly differentiated(G3)tumors(40%vs 22.4%P<0.05)was observed.More than every second patient below 40 years of age(51.8%)had distant metastases at diagnosis with a significant higher rate ring of signet cell differentiation compared to patients≥50 years(14.8%,P<0.05).Mutational status(KRAS,NRAS,BRAF,MSI)as well as selected behavioral risk factors showed no significant differences.CONCLUSION Distinct histopathologic features of increased biologic aggressiveness are found in patients with CRC of young-onset.Those patients present more frequently with more advanced tumor stages compared to older patients.Features of aggressive tumor biology underscore the need for earlier uptake of routine screening measures. | Matteo Mueller Marcel Andre Schneider Barla Deplazes Daniela Cabalzar-Wondberg Andreas Rickenbacher Matthias Turina | 2021 | World Journal of Gastrointestinal Surgery2021，13，2： | 3 |
| 4 | Anaplastic pancreatic cancer: Presentation, surgical management, and outcome显示文摘 | Oliver Strobel Werner Hartwig Frank Bergmann Ulf Hinz Thilo Hackert Lars Grenacher Lutz Schneider Stefan Fritz Matthias M. Gaida Markus W. Büchler Jens Werner | 2011 | Surgery2011，，2： | 2 |
| 5 | Self-expanding metal stents for the palliation of malignant gastric outlet obstruction in patients with peritoneal carcinomatosis显示文摘AIM To evaluate the efficacy of self-expanding metal stents(SEMS) for the palliation of malignant gastric outlet obstruction in patients with and without peritoneal carcinomatosis(PC).METHODS We performed a retrospective analysis of 62 patients who underwent SEMS placement for treatment of malignant gastroduodenal obstruction at our hospital over a six-year period. Stents were deployed through the scope under combined fluoroscopic and endoscopic guidance. Technical success was defined as successful stent placement and expansion. Clinical success was defined as an improvement in the obstructive symptoms and discharge from hospital without additional parenteral nutrition. According to carcinomatosis status, patients were assigned into groups with or without evidence of peritoneal disease.RESULTS In most cases, obstruction was caused by pancreatic(47%) or gastric cancer(23%). Technical success was achieved in 96.8%(60/62), clinical success in 79%(49/62) of all patients. Signs of carcinomatosis were identified in 27 patients(43.5%). The diagnosis was confirmed by pathology or previous operation in 7 patients(11.2%) and suspected by CT, MRI or ultrasound in 20 patients(32.2%). Presence of carcinomatosis was associated with a significantly lower clinical success rate compared to patients with no evidence of peritoneal disease(66.7% vs 88.6%, P = 0.036). There was no significant difference in overall survival between patients with or without PC(median 48 d vs 70 d, P = 0.21), but patients showed significantly longer survival after clinical success of SEMS placement compared to those experiencing clinical failure(median 14.5 d vs 75 d, P = 0.0003).CONCLUSION Given the limited therapeutic options and a clinical success rate of at least 66.7%, we believe that SEMS are a reasonable treatment option in patients with malignant gastric outlet obstruction with peritoneal carcinomatosis. | Christoph Rademacher Matthias Bechtler Steffen Schneider Bettina Hartmann Johannes Striegel Ralf Jakobs | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 6 | Perturbation results of critical elliptic equations of CaffareUi-Kohn-Niren- berg type显示文摘 | VERONICA FELLI MATTHIAS SCHNEIDER | 2003 | Journal of Differential Equations2003，191，1： | 1 |
| 7 | 5-Lipoxygenase and Leukotriene B 4 Receptor Are Expressed in Human Pancreatic Cancers But Not in Pancreatic Ducts in Normal Tissue显示文摘 | René Hennig Xian-Zhong Ding Wei-Gang Tong Matthias B. Schneider Jens Standop Helmut Friess Markus W. Büchler Parviz M. Pour Thomas E. Adrian | 2002 | The American Journal of Pathology2002，，2： | 1 |
| 8 | A Systematic Correlation of Angiography and High-Resolution Optical Coherence Tomography in Diabetic Macular Edema显示文摘 | Matthias Bolz Markus Ritter Miklos Schneider Christian Simader Christoph Scholda Ursula Schmidt-Erfurth | 2009 | Ophthalmology2009，，1： | 1 |
| 9 | Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology显示文摘 | Holger Amthauer Timm Denecke Beate Rau Bert Hildebrandt Michael Hünerbein Juri Ruf Ulrike Schneider Matthias Gutberlet Peter M. Schlag Roland Felix Peter Wust | 2004 | European Journal of Nuclear Medicine and Molecular Imaging2004，，6： | 1 |
| 10 | Bias in Meta-analysis detected by a simple,graphical test显示文摘 | Matthias Egger George Davey Smith Martin Schneider | 1998 | British Medical Journal1998，315，： | 1 |
| 11 | Bias in Meta-analysis Detected by a Simple, Graphical Test 显示文摘 | Matthias Egger George Davey Smith Martin Schneider | 1998 | British Medical Journal1998，315，： | 1 |
| 12 | Bias in Meta-analysis detected by a simple, graphical test 显示文摘 | Matthias Egger George Davey Smith Martin Schneider | 1998 | British Medical Journal1998，315，： | 1 |
| 13 | Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology显示文摘 | Holger Amthauer Timm Denecke Beate Rau Bert Hildebrandt Michael Hünerbein Juri Ruf Ulrike Schneider Matthias Gutberlet Peter M. Schlag Roland Felix Peter Wust | 2004 | European Journal of Nuclear Medicine and Molecular Imaging2004，，： | 1 |
| 14 | Development of vehicle sound quality--targets and methods显示文摘 | Matthias Schneider Michael Wilhelm | | Sea Paper0，，： | 1 |
| 15 | Alveolar stability under different combinations of positive end-expiratory pressure and tidal volume: alveolar microscopy in isolated injured rat lungs显示文摘背景高积极的结束吐气的压力(偷看) 和低潮汐的体积(vt ) 通风被认为是保护的通风策略。折迭的 aiveoli 的稳定在终止期间贡献肺保护,这被假设。然而,这个假设来自象肺的压力卷曲线的分析一样的间接索引的分析。学习是调查的这的目的借助于牙槽的显微镜学,偷看和 VI- 的联合关于牙槽的稳定性(I-E%) 在是有益的孤立健康、伤害的老鼠肺 .Methods 牙槽的稳定性在孤立的、非酒的机械地通气的老鼠肺被调查。受伤的肺与正常的肺相比。为两个组三个偷看背景(5, 10, 20 cmH_2O ) 与三个 vt 背景被相结合(6, 10, 15 ml/kg ) 每组导致九偷看 vt 联合。分析被牙槽的 microscopy.Results 在牙槽的稳定性在所有 偷看vt 联合坚持了的正常的肺执行(I-E%( 3.2 楤?浩潰瑲摥挠獡獥漠?潮敶?湩汦敵穮???丱?眠牥?潣瑮湩潵獵祬挠湯楦浲摥椠?桓湡桧楡?畢?桴牥?敷敲映睥爠灥牯獴漠?瑩?汣湩捩污瀠敲敳瑮瑡潩?湩?楨慮?桔?楡?景琠敨猠畴祤眠獡琠?湩敶瑳杩瑡?桴?敤潭牧灡楨?湡?汣湩捩污映慥畴敲?景琠敨氠'L牯瑡牯?潣普物敭?慣敳?湡?桴?牴慥浴湥?楷桴漠敳瑬浡癩物?瑥潨?敗瀠牥潦浲摥愠爠瑥潲灳'虡N敶猠畴祤椠?桴?桓湡桧楡倠'T楬?效污桴?楬楮慣?敃瑮牥??偁?? | LIU Hui Claudius A. Stahl Knut Moeller Matthias Schneider Steven Ganzert ZHAO Zhan-qi TONG Xiao-wen Josef Guttmann | 2010 | Chinese Medical Journal2010，，4： | 1 |
| 16 | Rectal Cancer: Mucinous Carcinoma on Magnetic Resonance Imaging Indicates Poor Response to Neoadjuvant Chemoradiation显示文摘 | Katja Oberholzer Matthias Menig Andreas Kreft Astrid Schneider Theodor Junginger Achim Heintz Karl-Friedrich Kreitner Andreas M. H?tker Torsten Hansen Christoph Düber Heinz Schmidberger | 2012 | International Journal of Radiation Oncology Biology Physics2012，，2： | 1 |
| 17 | Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical pilot study in 15 individual patients显示文摘 | Alfonso Ferrara Marion Nonn Peter Sehr Carola Schreckenberger Michael Pawlita Matthias Dürst Achim Schneider Andreas M. Kaufmann | 2003 | Journal of Cancer Research and Clinical Oncology2003，，9： | 1 |
| 18 | Development of Vehicle Sound Quality-Targets and Methods显示文摘 | Matthias Schneider Michael Wilhelm Norbert Alt | 1995 | SEA1995，，： | 1 |
| 19 | CAE process to eliminate powertrain noise and vibration显示文摘 | Matthias Schneider Hans-peter Lahey Christoph Steffens and Hans-Dieter Sonntag | 2002 | SAE2002，，： | 1 |
| 20 | The Development of organizational Strategies in Children: Evidence from a Micro genetic Longitudi- nal Study 显示文摘 | Matthias Schlagm Wolfgang Schneider | 2002 | Journal of Experimental Child Psychol- ogy2002，81，： | 1 |
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