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| 1 | The Hepatitis B e antigen (HBeAg) targets and suppresses activation of the Toll-like receptor signaling pathway显示文摘 | Tali Lang Camden Lo Narelle Skinner Stephen Locarnini Kumar Visvanathan Ashley Mansell | 2011 | Journal of Hepatology2011，，4： | 3 |
| 2 | IL 28 B genotype is not useful for predicting treatment outcome in A sian chronic hepatitis B patients treated with pegylated interferon‐α显示文摘 | Jacinta A Holmes Tin Nguyen Dilip Ratnam Neel M Heerasing Jane V Tehan Sara Bonanzinga Anouk Dev Sally Bell Stephen Pianko Robert Chen Kumar Visvanathan Rachel Hammond David Iser Ferry Rusli William Sievert Paul V Desmond D Scott Bowden Alexander J Thomps | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 3 | Equilibrium and kinetic study for the removal of malachite green using activated carbon prepared from Borassus flabello/er male flower显示文摘 | Babu PEJ Kumar V Visvanathan R | 2010 | Asia-Pacific Journal of Chemical Engineering2010，5，3： | 1 |
| 4 | The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection显示文摘 | Edward J. Gane Young-Suk Lim Stuart C. Gordon Kumar Visvanathan Eric Sicard Richard N. Fedorak Stuart Roberts Benedetta Massetto Zhishen Ye Stefan Pflanz Kimberly L. Garrison Anuj Gaggar G. Mani Subramanian John G. McHutchison Shyamasundaran Kottilil Brad | 2015 | Journal of Hepatology2015，，2： | 1 |
| 5 | Policy options to promote energy efficient and environmentally sound technolo- gies in small-and medium-scale industries 显示文摘 | Thiruchelvam M Kumar S Visvanathan C | 2003 | Energy Poli- cy2003，31，10： | 1 |
| 6 | Policy options to promote energy efficient and environmentally sound technologies in small and medium-scale industries显示文摘 | Thiruchelvam M Kumar S Visvanathan C | 2003 | Energy Policy2003，31，10： | 1 |
| 7 | Natural killer cells display impaired responses to toll like receptor 9 that support viral persistence in chronic hepatitis B显示文摘 | Dilip T. Ratnam William Sievert Kumar Visvanathan | 2012 | Cellular Immunology2012，，1： | 1 |
| 8 | Policy options to promote energy efficient and environmentally sound technologies in small and medium-scale industries显示文摘 | Thiruchelvam M Kumar S Visvanathan C | 2003 | Energy Policy2003，31，10： | 1 |
| 9 | Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers显示文摘 | Alexander J.V. Thompson Tin Nguyen David Iser Anna Ayres Kathy Jackson Margaret Littlejohn John Slavin Scott Bowden Edward J. Gane William Abbott George K.K. Lau Sharon R. Lewin Kumar Visvanathan Paul V. Desmond Stephen A. Locarnini | 2010 | Hepatology2010，，： | 1 |
| 10 | Acute pancreatitis caused by tipranavir/ritonavir-induced hypertriglyceridaemia显示文摘 | Scott JR Chapman Ian J Woolley Kumar Visvanathan Tony M Korman | 2007 | AIDS2007，，4： | 1 |
| 11 | Immune function biomarker QuantiFERON-monitor is associated with infection risk in cirrhotic patients显示文摘AIM To investigate whether a novel immune function biomarker Quanti FERON-Monitor(QFM) can identify cirrhotic patients at greatest risk of infection. METHODS Adult cirrhotic patients on the liver transplant waiting list were recruited for this observational cohort study from a tertiary liver transplant referral unit. The immune function biomarker, QFM was performed using the same method as the widely available Quantiferon-gold assay, and measures output in interferon gamma in IU/mL after dual stimulation of the innate and adaptive immune systems. Ninety-one cirrhotic patients were recruited, with 47(52%) transplanted on the day of their QFM. The remaining 44(48%) were monitored for infections until transplant, death, or census date of 1st February 2014.RESULTS Cirrhotic patients express a median QFM significantly lower than healthy controls(94.5 IU/mL vs 423 IU/mL), demonstrating that they are severely immunosuppressed.Several factors including model for end stage liver disease, presence of hepatocellular carcinoma, bilirubin, international normalized ratio and haemoglobin were associated with QFM on univariate analysis. Disease aetiology did not appear to impact QFM. On multivariate analysis, only Child-Pugh score and urea were significantly associated with a patient's immune function as objectively measured by QFM. In the 44 patients who were not transplanted immediately after their blood test and could be monitored for subsequent infection risk, 13(29.5%) experienced a pre-transplant infection a median 20 d(range 2-182) post-test. QFM < 214 IU/mL was associated with HR = 4.1(P = 0.01) for infection. A very low QFM < 30 IU/mL was significantly associated(P = 0.003) with death in three patients who died while awaiting transplantation(HR = 56.6).CONCLUSION QFM is lower in cirrhotics, allowing objective determinations of an individual's unique level of immune dysfunction. Low QFM was associated with increased susceptibility to infection. | Siddharth Sood Lijia Yu Kumar Visvanathan Peter William Angus Paul John Gow Adam Gareth Testro | 2016 | World Journal of Hepatology2016，8，35： | 0 |
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