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| 1 | Cytomegalovirus positive ulcerative colitis:A single center experience and literature review显示文摘AIM:To compare the clinical outcome of cytomegalovirus(CMV)-positive ulcerative colitis(UC) patients with and without antiviral therapy.METHODS:This was a retrospective case-controlled study.The database of UC patients in our institution was scanned for documented presence of CMV on colonic biopsies.Demographics,clinical data,endoscopy findings and pathology reports were extracted from the patients' charts and electronic records.When available,the data from colonoscopies preceding and following the diagnosis of colonic CMV infection were also ex-tracted.The primary outcomes of the study were colectomy/death during hospitalization and the secondary outcomes were colectomy/death through the course of the follow-up.RESULTS:Thirteen patients were included in the study,7(53.5%) of them were treated with gancyclovir and 6(46.5%) were not.Patients treated with antivirals presented with a more severe disease and 57% of them were treated with cyclosporine or infliximab before initiation of gancyclovir,while none of the patients without antivirals required rescue therapy.One patient died and another patient underwent urgent colectomy during hospitalization,both of them from the gancyclovir-treatment group.For the entire follow-up time(13 ± 13 mo),a total of 3 colectomies and one death occurred,all among the antiviral-treated patients(for colectomy:3/7 vs 0/6 patients,P = 0.19;for combined adverse outcome:4/7 vs 0/6 patients,P = 0.07).In 9/13 patients,immunohistochemistry for CMV was performed on biopsies obtained during a subsequent colonoscopy and was positive in one patient only.CONCLUSION:Gancyclovir-treated patients had a more severe disease and outcome,probably unrelated to antiviral therapy.Immunohistochemistry-CMV-positive patients with mild disease may recover without antiviral therapy. | Uri Kopylov Gila Sasson Bella Geyshis Michal Tepperberg Oikawa Iris Barshack Rami Eliakim Shomron Ben-Horin | 2013 | World Journal of Gastrointestinal Pathophysiology2013,4,1: | 10 |
| 2 | Selective Cytotoxic Effect of ZnO Nanoparticles on Glioma Cells显示文摘In this study we examined the cytotoxic effect of ZnO nanoparticles on various human cancer and normal cells.We found that the ZnO nanoparticles exerted a cytotoxic effect on the human glioma cell lines A172,U87,LNZ308,LN18,and LN229,whereas no cytotoxic effect was observed on normal human astrocytes.Similarly,the ZnO nanoparticles induced cell death in breast and prostate cancer cell lines while no major effect was observed in the respective normal breast and prostate cell lines.Using the fl uorescent dye 2,7-dichlorofl uorescein diacetate,we found that treatment of the glioma cells with ZnO nanoparticles induced a large increase in the generation of reactive oxygen species(ROS)and treatment of the cells with N-acetyl cysteine decreased the cytotoxic effect of the ZnO nanoparticles.In contrast,a smaller effect on ROS generation was observed in the normal astrocytes.These results suggest that ZnO nanoparticles may be employed as a selective cytotoxic agent for the eradication of cancer cells. | Stella Ostrovsky Gila Kazimirsky Aharon Gedanken Chaya Brodie | 2009 | Nano Research2009,2,11: | 5 |
| 3 | Non-Doppler Two-dimensional Strain Imaging by Echocardiography–From Technical Considerations to Clinical Applications显示文摘 | Gila Perk Paul A. Tunick Itzhak Kronzon | 2007 | Journal of the American Society of Echocardiography2007,,3: | 3 |
| 4 | Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients显示文摘 | Manuel Romero-Gómez Maria Del Mar Viloria Raúl J. Andrade Javier Salmerón Moisés Diago Conrado M. Fernández-Rodríguez Raquel Corpas Marina Cruz Lourdes Grande Luis Vázquez Paloma Mu?oz-de-Rueda Pilar López-Serrano Ana Gila María L. Gutiérrez Celia Pérez A | 2005 | Gastroenterology2005,,3: | 2 |
| 5 | The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines显示文摘 | Paul J. Austin Gila Moalem-Taylor | 2010 | Journal of Neuroimmunology2010,,1: | 2 |
| 6 | Tumor microRNA-29a expression and the risk of recurrence in stage IIcolon cancer显示文摘 | Alina Weissmann-Brenner Michal Kushnir Gila Lithwick Yanai Ranit Aharonov Hadas Gibori Ofer Purim Yulia Kundel Sara Morgenstern Marissa Halperin Yaron Niv Baruch Brenner | 2012 | International Journal of Oncology2012,,: | 2 |
| 7 | Congestion tolls and parking fees: A comparison of the potential effect on travel behavior显示文摘 | Gila Albert David Mahalel | 2006 | Transport Policy2006,13,: | 1 |
| 8 | Modeling the gas and particle flow inside cyclone separators 显示文摘 | CORTIS C GILA | 2007 | Progress in Energy and Combustion Science2007,33,: | 1 |
| 9 | Magnetic properties of n-GaMnN thin films显示文摘 | Thaler G T Overberg M E Gila B | 2002 | Applied Physics Letters2002,80,21: | 1 |
| 10 | Forecasting of electricity prices with neural networks显示文摘 | GARETA R ROMEO L M GILA | 2006 | Energy Convers Manage2006,47,: | 1 |
| 11 | Risk of Episiotomy and Perineal Lacerations Recurring After First Delivery显示文摘 | Sebastian Manzanares Davinia Cobo Maria Dolores Moreno‐Martínez Mar Sánchez‐Gila Alicia Pineda | 2013 | Birth2013,,4: | 1 |
| 12 | Asymptomatic dogs are highly competent to transmit Leishmania ( Leishmania ) infantum chagasi to the natural vector显示文摘 | Márcia Dalastra Laurenti Claudio Nazaretian Rossi Vania Lúcia Ribeiro da Matta Thaise Yumie Tomokane Carlos Eduardo Pereira Corbett Nágila Francinete Costa Secundino Paulo Filemon Paulocci Pimenta Mary Marcondes | 2013 | Veterinary Parasitology2013,,: | 1 |
| 13 | Detection of Pancreatic Carcinoma (Diagnostic Value of K-ras Mutations in Circulating DNA from Serum)显示文摘 | Livia Theodor Ehud Melzer Michael Sologov Gila Idelman Eitan Friedman Simon Bar-Meir | 1999 | Digestive Diseases and Sciences1999,,10: | 1 |
| 14 | Atrial natriuretic peptide levels after different types of inferior wall myocardial infarction显示文摘 | Assali A Gilas I Herz I | 1997 | Clin Cardiol1997,20,8: | 1 |
| 15 | Dietary trans fatty acids in early life: a review显示文摘 | LARQUE E ZAMORA S GILA | 2001 | Early Hum Develop2001,65,: | 1 |
| 16 | Activity-dependent modulation of axonal exitability in unmyelinated peripheral rat nerve fibers by the 5-HT(3) serotonin receptor显示文摘 | Philip ML Gila MT David JT | 2006 | J Neurophysiol2006,96,: | 1 |
| 17 | Improved Pt/Au and W/Pt/Au Schottky contacts on n-type ZnO using ozone cleaning显示文摘 | IP K GILA B P ONSTINE A H LAMBERS E S HEO Y W BAlK K H NORTON D P PEARTON S J KIM S LAROCHE J R REN F | 2004 | Appl Phys Lett2004,84,25: | 1 |
| 18 | Modeling the gas and particle flow inside cyclone separators显示文摘 | CORTES C GILA | 2007 | Progress in Energy and Combustion Science2007,33,5: | 1 |
| 19 | The influence of the initial acidity of HFER on the status of Co species and catalytic performance of CoFER and InCoFER in CH4 - SCR - NO 显示文摘 | Gila B Janas J Woch E | 2008 | Catalysis Today2008,,137: | 1 |
| 20 | MicroRNA expression differentiates between primary lung tumors and metastases to the lung显示文摘 | Iris Barshacka Gila Lithwick-Yanaic Arnon Afeka b | 2010 | Pathology-Research and Practice2010,206,: | 1 |