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| 1 | 急性缺血性卒中患者早期处理指南:美国心脏协会/美国卒中协会对医疗专业人员的指南(续前)显示文摘7静脉溶栓
7.1静脉rtPA
急性卒中的静脉溶栓治疗现已得到普遍接受。美国FDA于1996年批准静脉应用rtPA,部分基于NINDSrtPA卒中试验结果。 | Edward C. Jauch Jeffrey L. Saver Harold P. Adams Askiel Bruno J.J. (Buddy) Connors Bart M. Demaerschalk Pooja Khatri Paul W. McMullan Adnan I. Qureshi Kenneth Rosenfield Phillip A. Scott Debbie R. Summers David Z. Wang Max Wintermark Howard Yonas 李海峰(译) 岳耀先(译) 王琦(译) 张贤军(译) 丁晓君(译) | 2013 | 国际脑血管病杂志2013,21,8: | 975 |
| 2 | 全海水灌溉的作物——北美海蓬子(下)显示文摘 | 吕忠进 Edward P. Glenn Roy M. Hodges Carl Hodges | 2001 | 世界农业2001,,3: | 20 |
| 3 | Evolving concepts in bone infection: redefining “biofilm”,“acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy”显示文摘Osteomyelitis is a devastating disease caused by microbial infection of bone. While the frequency of infection following elective orthopedic surgery is low, rates of reinfection are disturbingly high. Staphylococcus aureus is responsible for the majority of chronic osteomyelitis cases and is often considered to be incurable due to bacterial persistence deep within bone. Unfortunately, there is no consensus on clinical classifications of osteomyelitis and the ensuing treatment algorithm. Given the high patient morbidity,mortality, and economic burden caused by osteomyelitis, it is important to elucidate mechanisms of bone infection to inform novel strategies for prevention and curative treatment. Recent discoveries in this field have identified three distinct reservoirs of bacterial biofilm including: Staphylococcal abscess communities in the local soft tissue and bone marrow, glycocalyx formation on implant hardware and necrotic tissue, and colonization of the osteocyte-lacuno canalicular network(OLCN) of cortical bone. In contrast, S.aureus intracellular persistence in bone cells has not been substantiated in vivo, which challenges this mode of chronic osteomyelitis. There have also been major advances in our understanding of the immune proteome against S. aureus, from clinical studies of serum antibodies and media enriched for newly synthesized antibodies(MENSA), which may provide new opportunities for osteomyelitis diagnosis, prognosis, and vaccine development. Finally, novel therapies such as antimicrobial implant coatings and antibiotic impregnated 3D-printed scaffolds represent promising strategies for preventing and managing this devastating disease. Here, we review these recent advances and highlight translational opportunities towards a cure. | Elysia A. Masters Ryan P. Trombetta Karen L. de Mesy Bentley Brendan F Boyce Ann Lindley Gill Steven R. Gill Kohei Nishitani Masahiro Ishikawa Yugo Morita Hiromu Ito Sheila N. Bello-Irizarry Mark Ninomiya James D. Brodell Jr. Charles C. Lee Stephanie P. Hao Irvin Oh Chao Xie Hani A. Awad John L. Daiss John R. Owen Stephen L. Kates Edward M. Schwarz Gowrishankar Muthukrishnan | 2019 | Bone Research2019,7,3: | 19 |
| 4 | 成人缺血性卒中早期处理指南显示文摘本指南旨在对成年急性缺血性卒中患者评价和治疗各要素的现有证据做一回顾。目标读者是那些为发病后48h内的卒中患者提供治疗的内科医生和其他急诊医疗保健人员。另外,也包括向医疗保健政策制定者提供的信息。方法:专家小组成员由美国心脏协会(AHA)卒中委员会科学声明监督委员会任命,他们代表了来自不同领域的专家。专家小组以2003年后发表的报道为重点,对相关文献进行回顾,采用AHA卒中委员会的证据水平分级标准对证据进行分级并做出推荐。本声明经专家小组认可后,再由AHA科学顾问和协调委员会进行同行评议和正式批准。本指南打算在3年内做全面更新。结果:对急性缺血性卒中患者的处理仍然是多方面的,包括尚未在临床试验中进行过验证的一些医疗诊治方面。本声明包括从急诊医疗服务人员开始接触患者到入院初期处理的推荐意见。静脉重组组织型纤溶酶原激活剂仍然是已得到证实的最有效的卒中急诊治疗干预方法。包括动脉应用溶栓药和机械介入在内的一些方法显示出希望。因为许多推荐是在有限的证据基础上做出的,因此需要对急性缺血性卒中的治疗进行更多的研究。 | Harold P. Adams Gregory del Zoppo Mark J. Alberts Deepak L. Bhatt Lawrence Brass Anthony Furlan Robert L. Grubb Randall T. Higashida Edward C. Jauch Chelsea Kidwell Patrick D. Lyden Lewis B. Morgenstern Adnan I. Qureshi Robert H. Rosenwasser Phillip A. Scott Eelco F.M. Wijdicks 李焰生(译) 熊昕丽(译) 林岩(译) 沈沸(译) 俞羚(译) 邹静(译) 张静芳(译) 孙亚蒙(译) 周洁茹(译) 蒋仙国(译) 陈莺(译) | 2007 | 国际脑血管病杂志2007,15,6: | 18 |
| 5 | 急性缺血性卒中患者早期处理指南:美国心脏协会/美国卒中协会对医疗专业人员的指南显示文摘背景和目的作者提供了关于成年急性缺血性卒中患者评估和治疗方面的现有证据和处理推荐的一份概述。目标读者为涉及急性缺血性卒中患者发病48h内诊治的院前诊疗人员、医生、综合医疗保健人员和医院管理者。该指南将取代先前的2007年版指南及其2009年更新版。方法著述委员会成员由美国卒中协会卒中委员会的科学声明监督委员会指定,代表各个领域的医疗专家。在形成共识的整个过程中,严格遵循美国心脏协会的利益冲突原则。委员会成员被分配给与其专业领域相关的内容,对卒中文献进行回顾,重点为前一版指南发表之后的文献,然后按照美国心脏协会卒中委员会的证据强度分级方案起草推荐意见。结果本指南的目的是减少卒中相关的残疾和死亡。本指南支持卒中医疗体系的全局性概念以及从患者识别、急救医疗服务激活、转送和分诊到急诊室和卒中单元内最初数小时诊治的卒中诊治细节。本指南讨论了早期卒中评估和一般治疗、缺血性卒中治疗、特殊干预措施,如再灌注策略以及脑复苏的一般生理学干预原则。结论由于许多推荐意见基于有限的证据,还迫切需要对急性缺血性卒中的治疗做进一步的研究。 | Edward C. Jauch Jeffrey L. Saver Harold P. Adams Askiel Bruno J.J. (Buddy) Connors Bart M. Demaerschalk Pooja Khatri Paul W. McMullan Jr, Adnan I. Qureshi Kenneth Rosenfield Phillip A. Scott Debbie R. Summers David Z. Wang Max Wintermark Howard Yonas 李海峰(译) 岳耀先(译) 王琦(译) 张贤军(译) 丁晓君(译) | 2013 | 国际脑血管病杂志2013,21,7: | 17 |
| 6 | 脑动静脉畸形的处理:美国心脏协会/美国卒中协会对医疗卫生专业人员发布的科学声明显示文摘背景本声明旨在复习目前脑动静脉畸形(brain arteriovenous malformations,bAVMs)的临床资料,为破裂或未破裂bAVMs的诊断和治疗提供建议。方法写作组通过面谈和电话会议的方式确定搜索关键词,讨论描述性文字和制定建议。作者通过PubMed、Medline或Embase完成各自相关章节的文献检索,时间截止到2015年1月底。声明草稿由同行评议专家以及卒中委员会科学监督委员会和卒中委员会领导委员会进行预先审查。结果本科学声明的重点细分为流行病学、诊断、自然史、治疗方案(包括开颅手术、立体定向放射外科和栓塞治疗的作用)以及破裂和未破裂bAVMs的处理,并且确定了需要更多证据支持的领域。结论bAVMs是一种相对少见但非常重要的出血性卒中病因,尤其是在年轻成人中。本声明描述了目前关于破裂和未破裂bAVMs的自然史和治疗方法的知识现状,同时提供了处理建议以及对将来研究的提示。 | Colin P. Derdeyn Gregory J. Zipfel Felipe C. Albuquerque Daniel L. Cooke Edward Feldmann Jason P. Sheehan James C. Tomer 盖延廷 王威 简新革 檀书斌 李彦江 彭方强 刘旻谛 宋冬雷 | 2017 | 国际脑血管病杂志2017,25,8: | 12 |
| 7 | 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference显示文摘 | Mitchell M. Levy Mitchell P. Fink John C. Marshall Edward Abraham Derek Angus Deborah Cook Jonathan Cohen Steven M. Opal Jean-Louis Vincent Graham Ramsay | 2003 | Critical Care Medicine2003,,4: | 7 |
| 8 | 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference显示文摘 | Mitchell M. Levy Mitchell P. Fink John C. Marshall Edward Abraham Derek Angus Deborah Cook Jonathan Cohen Steven M. Opal Jean-Louis Vincent Graham Ramsay | 2003 | Critical Care Medicine2003,,4: | 6 |
| 9 | Phase II Study of Everolimus in Patients with Metastatic Colorectal Adenocarcinoma Previously Treated with Bevacizumab-, Fluoropyrimidine-, Oxaliplatin-, and Irinotecan-Based Regimens显示文摘 | Kimmie Ng Josep Tabernero Jimmy Hwang Emilio Bajetta Sunil Sharma Salvatore A. Del Prete Edward R. Arrowsmith David P. Ryan Michaela Sedova Jin Jin Kamel Malek Charles S. Fuchs | 2013 | Clinical Cancer Research2013,,14: | 4 |
| 10 | MRC CRASH最终结果:一项成年脑损伤患者静脉使用糖皮质激素治疗6个月时预后的随机安慰剂对照试验 | Edwards P. Arango M. Balica L. 郭俊 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005,0,10: | 4 |
| 11 | 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference显示文摘 | Mitchell M. Levy Mitchell P. Fink John C. Marshall Edward Abraham Derek Angus Deborah Cook Jonathan Cohen Steven M. Opal Jean-Louis Vincent Graham Ramsay | 2003 | Intensive Care Medicine2003,,4: | 3 |
| 12 | Diagnosis and management of autoimmune hepatitis显示文摘 | Michael P. Manns Albert J. Czaja James D. Gorham Edward L. Krawitt Giorgina Mieli‐Vergani Diego Vergani John M. Vierling | 2010 | Hepatology2010,,: | 3 |
| 13 | Sofosbuvir and Ribavirin Prevent Recurrence of HCV Infection after Liver Transplantation: An Open-Label Study显示文摘 | Michael P. Curry Xavier Forns Raymond T. Chung Norah A. Terrault Robert Brown Jonathan M. Fenkel Fredric Gordon Jacqueline O’Leary Alexander Kuo Thomas Schiano Gregory Everson Eugene Schiff Alex Befeler Edward Gane Sammy Saab John G. McHutchison G. Mani S | 2014 | Gastroenterology2014,,: | 3 |
| 14 | Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease显示文摘 | Edward M. Kennedy Leda C. Bassit Henrik Mueller Anand V.R. Kornepati Hal P. Bogerd Ting Nie Payel Chatterjee Hassan Javanbakht Raymond F. Schinazi Bryan R. Cullen | 2014 | Virology2014,,: | 3 |
| 15 | 美国国家卒中协会对短暂性脑缺血发作诊治体系的推荐意见显示文摘短暂性脑缺血发作(transient ischemic attack,TIA)很常见,预示短期卒中风险很高。有关TIA患者紧急评价和治疗的循证推荐意见已经发表。然而,这些推荐意见的可靠和一致的执行需要对现有TIA诊治体系做出相应的改变。美国国家卒中协会召集了一个多学科专家小组,提出了医院内TIA诊治体系主要内容的推荐意见,以提高对TIA患者的诊疗质量。专家小组推荐医院制定标准化方案,以确保对TIA患者实施快速和完整的评价和处理,特别关注对卒中高危患者进行紧急而密切的观察。 | S. Claibome Johnston Gregory W. Albers Philip B. Gorelick Ethan Cumbler Jeffrey Klingman Michael A. Ross Meg Brisgs Jean Carlton Edward P. Sloan Uzma Vaince 李海峰(译) 洪宇(译) 王琦(译) | 2011 | 国际脑血管病杂志2011,19,9: | 3 |
| 16 | Risk for Immune-Mediated Graft Dysfunction in Liver Transplant Recipients With Recurrent HCV Infection Treated With Pegylated Interferon显示文摘 | Josh Levitsky Maria Isabel Fiel John P. Norvell Edward Wang Kymberly D. Watt Michael P. Curry Sumeet Tewani Timothy M. McCashland Maarouf A. Hoteit Abraham Shaked Samuel Saab Amanda C. Chi Amy Tien Thomas D. Schiano | 2012 | Gastroenterology2012,,5: | 3 |
| 17 | Mycoplasma pneumoniae in children with acute and refractory asthma显示文摘 | Pamela R. Wood Vanessa L. Hill Margaret L. Burks Jay I. Peters Harjinder Singh Thirumalai R. Kannan Shruthi Vale Marianna P. Cagle Molly F.R. Principe Joel B. Baseman Edward G. Brooks | 2013 | Annals of Allergy Asthma & Immunology2013,,5: | 2 |
| 18 | Sofosbuvir and Ribavirin for Treatment of Compensated Recurrent Hepatitis C Virus Infection After Liver Transplantation显示文摘 | Michael Charlton Edward Gane Michael P. Manns Robert S. Brown Michael P. Curry Paul Y. Kwo Robert J. Fontana Richard Gilroy Lewis Teperman Andrew J. Muir John G. McHutchison William T. Symonds Diana Brainard Brian Kirby Hadas Dvory-Sobol Jill Denning Sara | 2014 | Gastroenterology2014,,: | 2 |
| 19 | Hepatitis B virus testing by minipool nucleic acid testing: does it improve blood safety?显示文摘 | Susan L. Stramer Edward P. Notari David E. Krysztof Roger Y. Dodd | 2013 | Transfusion2013,,: | 2 |
| 20 | Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction: Implications for Patients With and Without Recognized Diabetes显示文摘 | Mikhail Kosiborod Saif S. Rathore Silvio E. Inzucchi Frederick A. Masoudi Yongfei Wang Edward P. Havranek Harlan M. Krumholz | 2005 | Circulation2005,,23: | 2 |