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| 1 | 远程耦合世界的可持续性框架显示文摘远距离之间的相互作用及其影响日益广泛。这种远程相互作用往往会对可持续发展产生深远的影响并会造成意想不到的结果。很多可持续性研究都是针对某个特定地点进行的,很少注重多个地点之间远程相互作用对可持续性所产生的影响。虽然有些研究涉及到远程因素,但通常都把它们看作外在变量,而未把它们看作反馈。为了更好地理解和综合各种远程相互作用,本文提出了一种基于远程耦合的综合框架,它是一个远距离社会经济和环境相互作用的总体概念。人类与自然耦合系统是研究在特定地点发生的相互作用,远程耦合概念是对人类与自然耦合系统研究的自然延伸。远程耦合框架包括五个相关的组成部分,即:人类与自然耦合系统、流、代理、原因、和影响。本文通过农产品贸易和物种入侵两个远程相互作用的例子来解释远程耦合框架,重点阐述远程耦合框架的影响,并讨论促进远程耦合研究发展的研究条件和方法。这个框架有助于分析系统内各组成部分以及它们之间的相互关系,找出研究差距,探索其中的隐含成本以及尚未开发的优势,提供引入反馈及多系统(发送、接收和外溢系统)之间权衡和协同的有效手段,从本地到全球各个层面加深对远程相互作用的认识,并提高社会经济和环境可http://gffzz31576c8fc0de4618h55p6qukvun9n6pc0.ffgz.tsg.suse.edu.cn续发展政策的有效性。 | 刘建国 Vanessa Hull Mateus Batistella Ruth DeFries Thomas Dietz 付峰 Thomas W.Hertel R.Cesar Izaurralde Eric F.Lambin 李舒心 Luiz A.Martinelli William J.McConnell Emilio F.Moran Rosamond Naylor 欧阳志云 KarenR.Polenske Anette Reenberg Gilberto de Miranda Rocha Cynthia S.Simmons Peter H.Verburg Peter M.Vitousek 张福锁 朱春全 | 2016 | 生态学报2016，36，23： | 19 |
| 2 | Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth显示文摘AIM: Standard immunosuppression after organ transplantation stimulates tumor growth. Sirolimus has a strong antiproliferative and a tumor inhibiting effect. The purpose is to assess the effect on tumor growth of the immunosuppressive compounds sirolimus and tacrolimus alone and in combination on cells of human hepatocellular carcinoma.METHODS: We used the human cell lines SK-Hep 1 and Hep 3B derived from hepatocellular carcinoma. Proliferation analyses after treatment with sirolimus, tacrolimus, or the combination of both were performed. FACS analyses were done to reveal cell cycle changes and apoptotic cell death. The expression of apoptosis-related proteins was estimated by Western blots.RESULTS: Sirolimus alone or combined with tacrolimus inhibited the growth of both cell lines after 5 d by up to 35% in SK-Hep 1 cells, and by up to 68% in Hep 3B cells at 25 ng/mL. Tacrolimus alone stimulated the growth by 12% after 5 ng/mL and by 25% after 25 ng/mL in Hep 3B cells. We found an increase of apoptotic Hep 3B cells from 6 to 16%, and a G1-arrest in SK-Hep 1 cells with an increase of cells from 61 to 82%, when sirolimus and tacrolimus were combined. Bcl-2 was down-regulated in Hep 3B, but not in SK-Hep 1 cells after combined treatment.CONCLUSION: Sirolimus appears to inhibit the growth of hepatocellular carcinoma cells alone and in combination with tacrolimus. Sirolimus seems to inhibit the growth stimulation of tacrolimus. | Guido Schumacher Marijke Oidtmann Anne Rueggeberg Dietmar Jacob Sven Jonas Jan M. Langrehr Ruth Neuhaus Marcus Bahra Peter Neuhaus | 2005 | World Journal of Gastroenterology2005，11，10： | 14 |
| 3 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 4 | Characteristics of the Chinese subjects entered the Hypertension in the Very Elderly Trial显示文摘在多民族的试用的病人的基线特征是的背景可能,与比较的心血管的 outcome.This 学习有关,病人的基线特征在中国招募了,那些在超过 80 年岁的 508 个中国高血压的男人和进入了高血压在的 728 个女人全部的另外的 countries.Methods A 招募了老试用( HYVET )与在 860 个男人和在另外的 countries.Results 进入了试用的 1 348 个女人的那些相比中国 | LIU Li-sheng WANG Ji-guang MA Shu-ping WANG Wen LU Fang-hong ZHANG Liang-qing Winston Banya Ruth Peters Nigel Beckett Astrid Fletcher Christopher J. Bulpitt | 2008 | Chinese Medical Journal2008，，16： | 5 |
| 5 | Increasing applicability of liver transplantation for patients with hepatitis B–related liver disease显示文摘 | Thomas Steinmüller Daniel Seehofer Nada Rayes Andrea R. Müller Utz Settmacher Sven Jonas Ruth Neuhaus Thomas Berg Uwe Hopf Peter Neuhaus | 2002 | Hepatology2002，，6： | 2 |
| 6 | Increasing applicability of liver transplantation for patients with hepatitis B–related liver disease显示文摘 | Thomas Steinmüller Daniel Seehofer Nada Rayes Andrea R. Müller Utz Settmacher Sven Jonas Ruth Neuhaus Thomas Berg Uwe Hopf Peter Neuhaus | 2002 | Hepatology2002，，6： | 2 |
| 7 | Inter-observer agreement for Crohn’s disease sub-phenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study显示文摘 | Krupa Krishnaprasad Jane M. Andrews Ian C. Lawrance Timothy Florin Richard B. Gearry Rupert W.L. Leong Gillian Mahy Peter Bampton Ruth Prosser Peta Leach Laurie Chitti Charles Cock Rachel Grafton Anthony R. Croft Sharon Cooke James D. Doecke Graham L. Rad | 2011 | Journal of Crohn’s and Colitis2011，，3： | 2 |
| 8 | 农民工社区网络与行动显示文摘古学斌(香港理工大学应用社会科学系):行动研究
我是做农村研究的,也会在农村开展一些农村行动研究的项目。一直以来学院里面的研究都基本是传统的研究,主要是为了理解而做的研究,而不是以推动社会变迁或社会改革而进行的研究。我们今天讲农民工话题,在座的诸位也可能希望能够有进一步的行动。在这个方面,也许行动研究有一定的意义。由于时间关系,我今天主要讲讲行动研究的内涵和行动研究的一些重要原则。 | 古学斌 任焰 陈敬慈 郑广怀 Ruth Milkman Peter Evans | 2009 | 开放时代2009，，7： | 2 |
| 9 | Context-dependent and invariant associations between lipids, lipeproteins and apolipoproteins and lipeprotein E genotype 显示文摘 | Ruth FS Birglt AL Peter S | 2000 | J Lioid Res2000，41，11： | 1 |
| 10 | Molecular structure of low density lipoprotein: current status and future challenges显示文摘 | Ruth Prassl Peter Laggner | 2009 | European Biophysics Journal2009，，2： | 1 |
| 11 | Immunogenicity of a new purified fusion protein vaccine to respiratory syncytial virus: a multi-center trial in children with cystic fibrosis显示文摘 | Pedro A. Piedra Stanley G. Cron Alan Jewell Nicole Hamblett Ruth McBride Melisa A. Palacio Richard Ginsberg Christopher M. Oermann Peter W. Hiatt | 2003 | Vaccine2003，，19： | 1 |
| 12 | The incidence and significance of accidental hypothermia in major trauma-a prospective observational study显示文摘 | Sharyn I Ruth E Peter C | 2011 | Resuscitation2011，82，3： | 1 |
| 13 | MRI assessment of knee osteoarthritis: Knee Osteoarthritis Scoring System (KOSS)—inter-observer and intra-observer reproducibility of a compartment-based scoring system显示文摘 | Peter R. Kornaat Ruth Y. T. Ceulemans Herman M. Kroon Naghmeh Riyazi Margreet Kloppenburg Wayne O. Carter Thasia G. Woodworth Johan L. Bloem | 2005 | Skeletal Radiology2005，，2： | 1 |
| 14 | Oxidative albumin damage in chronic liver failure: Relation to albumin binding capacity, liver dysfunction and survival显示文摘 | Karl Oettl Ruth Birner-Gruenberger Walter Spindelboeck Hans Peter Stueger Livia Dorn Vanessa Stadlbauer Csilla Putz-Bankuti Peter Krisper Ivo Graziadei Wolfgang Vogel Carolin Lackner Rudolf E. Stauber | 2013 | Journal of Hepatology2013，，5： | 1 |
| 15 | Outcome after liver re‐transplantation in patients with recurrent chronic hepatitis C显示文摘 | Marcus Bahra Ulf Peter Neumann Dietmar Jacob Thomas Berg Ruth Neuhaus Jan Michael Langrehr Peter Neuhaus | 2007 | Transplant International2007，，9： | 1 |
| 16 | Modification of the lipid-protein interaction in human low-density lipoprotein destabilizes ApoB-100 and decreases oxidizability显示文摘 | Peter MA Karl L Ruth P | 1999 | Biochemistry1999，38，： | 1 |
| 17 | Donor evaluation, donor risks, donor outcome, and donor quality of life in adult-to-adult living donor liver transplantation显示文摘 | Andreas Pascher Igor M. Sauer Marc Walter Enrique Lopez-Haeninnen Tom Theruvath Antonino Spinelli Ruth Neuhaus Utz Settmacher Andrea R. Mueller Thomas Steinmueller Peter Neuhaus | 2002 | Liver Transplantation2002，，9： | 1 |
| 18 | The theoretical underpinnings of customer asset management: A framework and propositions for future research显示文摘 | Ruth N. Bolton Katherine N. Lemon Peter C. Verhoef | 2004 | Journal of the Academy of Marketing Science2004，，： | 1 |
| 19 | Alcoholysis of triacylglycerols by heterogeneous catalysis显示文摘 | Siegfried K F Peter Ruth G Hans-Peter N | 2002 | Technology2002，104，： | 1 |
| 20 | A self-management approach using self-initiated action plans for symptoms with ongoing nurse support in patients with Chronic Obstructive Pulmonary Disease(COPD)and comorbidities:the COPE-III study protocol显示文摘 | Lenferink Anke Frith Peter van der Valk Paul Buckman Julie Sladek Ruth Cafarella Paul van der Palen Job Effing Tanja | 2013 | Contemporary clinical trials2013，36，1： | 1 |
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