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| 1 | Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn’s disease patients显示文摘AIM:To investigate the interaction of interleukin-23 receptor(IL23R)(rs1004819 and rs2201841),autophagy-related 16-like 1(ATG16L1)(rs2241880), caspase recruitment domain-containing protein 15 (CARD15)genes,and IBD5 locus in Crohn's disease(CD) patients. METHODS:A total of 315 unrelated subjects with CD and 314 healthy controls were genotyped.Interactions and specific genotype combinations of a total of eight variants were tested.The variants of IBD5locus(IGR2198a_1 rs11739135 and IGR2096a_1 rs12521868),CARD15(R702W rs2066845 and L1007fs rs2066847),ATG16L1(rs2241880)and IL23R (rs1004819,rs2201841)genes were genotyped by PCR-RFLP,the G908R(rs2066844)in CARD15 was determined by direct sequencing. RESULTS:The association of ATG16L1 T300A with CD was confirmed[P=0.004,odds ratio(OR)=1.69, 95%CI:1.19-2.41],and both IL23R variants were found to represent significant risk for the disease(P= 0.008,OR=2.05,95%CI:1.20-3.50 for rs1004819 AA;P<0.001,OR=2.97,95%CI:1.65-5.33 for rs2201841 CC).Logistic regression analysis of pairwise interaction of the inflammatory bowel disease (IBD)loci indicated that IL23R,ATG16L1,CARD15 and IBD5(IGR2198a_1)contribute independently to disease risk.We also analysed the specific combina- tions by pair of individual ATG16L1,IL23R rs1004819, rs2201841,IGR2198a_1,IGR2096a_1 and CARD15 genotypes for disease risk influence.In almost all cases,the combined risk of susceptibility pairs was higher in patients carrying two different risk-associated gene variants together than individuals with just one polymorphism.The highest OR was found for IL23R rs2201841 homozygous genotype with combination of positive CARD15 status(P<0.001,OR=9.15,95% CI:2.05-40.74). CONCLUSION:The present study suggests a cumulative effect of individual IBD susceptibility loci. | Veronika Csngei Luca Járomi EnikSáfrány Csilla Sipeky Lili Magyari Bernadett Faragó Judit Bene Noémi Polgár Lilla Lakner Patrícia Sarlós Márta Varga Béla Melegh | 2010 | World Journal of Gastroenterology2010，16，2： | 2 |
| 2 | Relapsing polychondritis with p-ANCA associated vasculitis: Which triggers the other?显示文摘Relapsing polychondritis(RP) is a rare autoimmune disease with chronic inflammatory/destructive lesions of the cartilaginous tissues. In one third of the cases it is associated with other autoimmune disorders, mostly with anti-neutrophil cytoplasmic antibody(ANCA) associated vasculitis(AAV). We report three cases of RP with p-ANCA positive AAV. In the first patient RP developed 1.5 years after the onset of AAV. In the others the signs of RP were present before the onset of severe crescent glomerulonephritis. Patients responded well on steroid and cyclophosphamide. In dialysis dependent cases plasmapheresis was also used successfully. During the 2 and 1.5 years of follow up, they were symptom-free, and had stable glomerular filtration rate. The first patient died after four years of follow-up due to the complications of sudden unset pancytopenia,which raises the possibility of associated hemophagocytic syndrome. In the setting of RP or AAV physicians should always be aware of the possibility of sudden or insidious appearance of the other disease. | Ibolya File Csilla Trinn Zsolt Mátyus László Ujhelyi József Balla János Mátyus | 2014 | World Journal of Clinical Cases2014，2，12： | 1 |
| 3 | Genetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor显示文摘 | Stephen J. Murphy Steven N. Hart Joema Felipe Lima Benjamin R. Kipp Mitchell Klebig Jennifer L. Winters Csilla Szabo Lizhi Zhang Bruce W. Eckloff Gloria M. Petersen Steven E. Scherer Richard A. Gibbs Robert R. McWilliams George Vasmatzis Fergus J. Couch | 2013 | Gastroenterology2013，，5： | 1 |
| 4 | Viral hepatitis: New data on hepatitis C infection显示文摘 | Erzsébet Szabó Gabor Lotz Csilla Páska András Kiss Zsuzsa Schaff | 2003 | Pathology & Oncology Research2003，，4： | 1 |
| 5 | Determination of traces of cobalt in the presence of nioxime and cetyltrimethylammonium bromide by adsorptive stripping voltammetry显示文摘 | Aleksandra Szydlowska-Czerniak Csilla Dianoczki Katalin Recseg | 2008 | Talanta2008，76，： | 1 |
| 6 | A New ZearalenoneBiodegradation Strategy Using Non-Pathogenic Rhodococcuspyridinivorans K408 Strain 显示文摘 | R6kus K Csilla K S^ndor S | 2012 | PLOS ONE2012，7，43： | 1 |
| 7 | Adrenal masses in children显示文摘 | Csilla Balassy Oscar M. Navarro Alan Daneman | 2011 | Radiologic Clinics of North America2011，，： | 1 |
| 8 | Oxidative albumin damage in chronic liver failure: Relation to albumin binding capacity, liver dysfunction and survival显示文摘 | Karl Oettl Ruth Birner-Gruenberger Walter Spindelboeck Hans Peter Stueger Livia Dorn Vanessa Stadlbauer Csilla Putz-Bankuti Peter Krisper Ivo Graziadei Wolfgang Vogel Carolin Lackner Rudolf E. Stauber | 2013 | Journal of Hepatology2013，，5： | 1 |
| 9 | Clinical applicability of a mathematical model in assessing the functional ability of the communicating arteries of the circle of Willis显示文摘 | László Orosz Arjan W. Hoksbergen Csilla Molnár Péter Siró Francis Cassot Jean-Pierre Marc-Vergnes Béla Fülesdi | 2009 | Journal of the Neurological Sciences2009，，1： | 1 |
| 10 | Managing brands and customer engagement in online brand communities显示文摘 | Jochen Wirtz Anouk den Ambtman Josée Bloemer Csilla Horváth B. Ramaseshan Joris van de Klundert Zeynep Gurhan Canli Jay Kandampully | 2013 | Journal of Service Management2013，，3： | 1 |
| 11 | SJES14110700244508显示文摘 | Csilla Müller Leontin David Vasile Chi? Simona Cint? P?nzaru | 2014 | Food Chemistry2014，，： | 1 |
| 12 | Anti-Galectin-3 IgG Autoantibodies in Patients with Crohn’s Disease Characterized by Means of Phage Display Peptide Libraries显示文摘 | Erika Jensen-Jarolim Christian Neumann Georg Oberhuber Regina Gscheidlinger Csilla Neuchrist Walter Reinisch Riaz I. Zuberi Edward Penner Fu-Tong Liu George Boltz-Nitulescu | 2001 | Journal of Clinical Immunology2001，，5： | 1 |
| 13 | Paraneoplastic rheumatic syndromes显示文摘 | Csilla András Zoltán Csiki Andrea Ponyi árpád Illés Katalin Dankó | 2006 | Rheumatology International2006，，5： | 1 |
| 14 | Com- parison of two analytical methods for assessing antioxidant capacity of rapeseed and olive oils 显示文摘 | ALEKSANDRA S C GYORGY K CSILLA D | 2008 | J Am Oil Chem Soc2008，85，： | 1 |
| 15 | 显示文摘 | Arpad Molnar Csilla Keresszegi Bela Torok | 1999 | Appl Catal A: General1999，189，： | 1 |
| 16 | Ontology Guided XML Security Engine显示文摘 | Andrei Stoica Csilla Farkas | 2004 | Journal of Intelligent Information System2004，23，3： | 1 |
| 17 | Phil- ipp, Imaging of the scrotum in children 显示文摘 | Marcus Hormarm Csilla Balassy Marcel O | 2004 | Eur Radiol2004，，14： | 1 |
| 18 | Viral hepatitis: New data on hepatitis C infection显示文摘 | Erzsébet Szabó Gabor Lotz Csilla Páska András Kiss Zsuzsa Schaff | 2003 | Pathology & Oncology Research2003，，4： | 1 |
| 19 | History and future of food irradiation显示文摘 | JO’ZSEF FARKAS CSILLA MOHA'CSI-FARKAS | 2011 | Trends in Food Science&Technology2011，22，： | 1 |
| 20 | The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox) 显示文摘 | GERGELY S ANDRAS V CSILLA 0 L | 2008 | Drug Discov Today2008，13，910： | 1 |
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