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| 1 | Identification of CD13,CD107a,and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-de-pendent upregulation显示文摘Using two-colour flow cytometry >200 antibodies submitted to the 8th International Workshop of Human Leukocyte Differentiation Antigens (HLDA8) have been analyzed for their reactivity with resting and activated CD203c+ basophils. Four antibodies either non-reactive or weakly reactive with resting basophils exhibited an increased reactivity with basophils activated by anti-IgE-mediated cross-linking of the high affinity IgE receptor (FcεRI). These include antibod- ies against CD164 (WS-80160, clone N6B6 and WS-80162, clone 67D2), as well as two reagents with previously unknown specificities that were identified as CD13 (WS-80274, clone A8) and CD107a (WS-80280, clone E63-880). The activation patterns followed either the “CD203c-like” or “CD63-like” activation profile. The CD203c profile is characterized by a rapid and significant upregulation (of CD13, CD164, and CD203c), reaching maximum levels after 5- 15 min of stimulation. The phosphoinositide-3-kinase (PI3K)-specific inhibitor wortmannin inhibited the upregulation of these markers whereas 12-O-tetradecanoyl-phorbol-13-acetate (TPA) induced a rapid and FcεRI-independent upregulation within 1-2 min. In the CD63 profile, maximum upregulation (of CD63 and CD107a) was detected only after 20-40 min, and upregulation by TPA reached maximum levels after 60 min. In summary, our data identify CD13, CD107a, and CD164 as novel basophil-activation antigens. Based on time kinetics of upregulation, we hypothesize that molecules of the “CD203c group” and the “CD63 group” are linked to two different mechanisms of basophil activation. | Florian HENNERSDORF Stefan FLORIAN Andreas JAKOB Katharina BAUMGRTNER Karoline SONNECK Alfred NORDHEIM Tilo BIEDERMANN Peter VALENT Hans-Jrg BüHRING | 2005 | Cell Research2005，15，5： | 9 |
| 2 | Localization of a Novel Locus for Autosomal Recessive Early-Onset Parkinsonism, PARK6, on Human Chromosome 1p35-p36显示文摘 | Enza Maria Valente Anna Rita Bentivoglio Peter H. Dixon Alessandro Ferraris Tamara Ialongo Marina Frontali Alberto Albanese Nicholas W. Wood | 2001 | The American Journal of Human Genetics2001，，4： | 1 |
| 3 | Detection of molecular targets on the surface of CD34+/CD38? stem cells in various myeloid malignancies显示文摘 | Stefan Florian Karoline Sonneck Alexander W. Hauswirth Maria-Theresa Krauth Gerit-Holger Schernthaner Wolfgang R. Sperr Peter Valent | 2006 | Leukemia & Lymphoma2006，，2： | 1 |
| 4 | Prognostic value of lactate dehydrogenase activity in myelodysplastic syndromes显示文摘 | Friedrich Wimazal Wolfgang R Sperr Michael Kundi Petra Meidlinger Christa Fonatsch John-Hendrik Jordan Renate Thalhammer-Scherrer Ilse Schwarzinger Klaus Geissler Klaus Lechner Peter Valent | 2001 | Leukemia Research2001，，： | 1 |
| 5 | The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia显示文摘 | Heidrun Karlic Harald Herrmann Franz Varga Roman Thaler Rene Reitermaier Silvia Spitzer Viviane Ghanim Katharina Blatt Wolfgang R. Sperr Peter Valent Michael Pfeilst?cker | 2013 | Critical Reviews in Oncology / Hematology2013，，： | 1 |
| 6 | Low erythropoietin production as non-oncogenoc co-factor contributing to disease-manifestation in low-risk MDS: A hypothesis supported by unique case reports显示文摘 | Peter Valent | 2008 | Leukemia Research2008，38，2： | 1 |
| 7 | Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis显示文摘 | Florian Grebien Oliver Hantschel John Wojcik Ines Kaupe Boris Kovacic Arkadiusz M. Wyrzucki Gerald D. Gish Sabine Cerny-Reiterer Akiko Koide Hartmut Beug Tony Pawson Peter Valent Shohei Koide Giulio Superti-Furga | 2011 | Cell2011，，2： | 1 |
| 8 | Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference显示文摘 | Peter Valent Hans-Peter Horny John M. Bennett Christa Fonatsch Ulrich Germing Peter Greenberg Torsten Haferlach Detlef Haase Hans-Jochen Kolb Otto Krieger Michael Loken Arjan van de Loosdrecht Kiyoyuki Ogata Alberto Orfao Michael Pfeilst?cker Bj?rn Rüter | 2007 | Leukemia Research2007，，6： | 1 |
| 9 | Aberrant expression of CD30 in aggressive systemic mastocytosis and mast cell leukemia: a differential diagnosis to consider in aggressive hematopoietic CD30-positive neoplasms显示文摘 | Peter Valent Karl Sotlar Hans-Peter Horny | 2011 | Leukemia & Lymphoma2011，，5： | 1 |
| 10 | Morphologic and Immunophenotypic Properties of Neoplastic Cells in a Case of Mast Cell Sarcoma显示文摘 | Andreas Chott Philipp Guenther Angela Huebner Edgar Selzer Reza M. Parwaresch Hans-Peter Horny Peter Valent | 2003 | The American Journal of Surgical Pathology2003，，7： | 1 |
| 11 | Effect of silver-nanoparticles generated in poly(vinyl alcohol)membranes on ethanol dehydration via pervaporation显示文摘Pervaporation is an important membrane separation method of chemical engineering.In this work,silver-nanoparticles-poly(vinyl alcohol)nanocomposite membranes(AgNPs-PVA)are produced for the sake of improving its potentials for pervaporation of ethanol–water mixture so that the usual opposite trend between membrane selectivity and permeation can be reduced.The nanocomposite membranes are fabricated from an aqueous solution of poly(vinyl alcohol)with silver nanoparticles via the in-situ generation technique in the absence of any reducing agent.Successful generation of the nano size silver is measured by the UV–vis spectrum showing a single peak at 419 nm due to the plasmonic effect of silver nanoparticles.Our nanocomposite AgNPs-PVA membranes are characterized using scanning electron microscope(SEM),Fourier-transform infrared(FT-IR)spectroscopy,X-ray diffraction and thermogravimetric analysis(TGA).The pervaporation tests of our new AgNPs-PVA membranes show good results since at a higher temperature and higher ethanol concentration in the feed,the prepared membranes are highly permeable for the water having stable selectivity values and therefore our membranes show better performance compared to that of the other PVA-based nanocomposite membranes. | Asmaa Selim Andras Jozsef Toth Daniel Fozer Eniko Haaz Nóra Valentínyi Tibor Nagy Orsolya Keri Lászlo Péter Bakos Imre Miklós Szilágyi Peter Mizsey | 2019 | Chinese Journal of Chemical Engineering2019，27，7： | 0 |
| 12 | The Vienna Cancer Stem Cell Club (VCSCC): First 10 Years and Future Perspectives显示文摘 | Peter Valent | 2013 | Journal of Life Sciences2013，7，6： | 0 |
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