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| 1 | Current concepts on osteonecrosis of the femoral head显示文摘It is estimated that 20000 to 30000 new patients are diagnosed with osteonecrosis annually accounting for approximately 10% of the 250000 total hip arthroplasties done annually in the United States. Thelack of level 1 evidence in the literature makes it difficult to identify optimal treatment protocols to manage patients with pre-collapse avascular necrosis of the femoral head, and early intervention prior to collapse is critical to successful outcomes in joint preserving procedures. There have been a variety of traumatic and atraumatic factors that have been identified as risk factors for osteonecrosis, but the etiology and pathogenesis still remains unclear. Current osteonecrosis diagnosis is dependent upon plain anteroposterior and frog-leg lateral radiographs of the hip, followed by magnetic resonance imaging(MRI). Generally, the first radiographic changes seen by radiograph will be cystic and sclerotic changes in the femoral head. Although the diagnosis may be made by radiograph, plain radiographs are generally insufficient for early diagnosis, therefore MRI is considered the most accurate benchmark. Treatment options include pharmacologic agents such as bisphosphonates and statins, biophysical treatments, as well as joint-preserving and joint-replacing surgeries. the surgical treatment of osteonecrosis of the femoral head can be divided into two major branches: femoral head sparing procedures(FHSP) and femoral head replacement procedures(FHRP). In general, FHSP are indicated at pre-collapse stages with minimal symptoms whereas FHRP are preferred at post-collapse symptomatic stages. It is difficult to know whether any treatment modality changes the natural history of core decompression since the true natural history of core decompression has not been delineated. | Joaquin Moya-Angeler Arianna L Gianakos Jordan C Villa Amelia Ni Joseph M Lane | 2015 | World Journal of Orthopedics2015，6，8： | 94 |
| 2 | 精确农业田间土壤空间变异与采样方式研究显示文摘以英国 Hillsborough农业研究所附近的一块 7.9hm2的牧草地为研究区 ,采用地统计的半方差分析和克立格方法研究其空间变异性和空间插值。同时对研究田块的样点根据不同间距、不同形状进行删选 ,对不同布局状况下的结果进行统计比较 ,以获取满足一定精度下的最少采样个数和采样形状。研究结果表明 ,单纯利用样方统计 ,土壤有效钾需要 6 5个采样点 ,大致为原始采样点的一半。而在考虑空间采样形状和空间插值效果 ,再采用最小显著性差异 (L SD)进行比较 ,该田块土壤有效钾采样最好使用规则三角网布点 (样点数为 6 2个 )。 | 王珂 沈掌泉 John S.Bailey Craw ford Jordan | 2001 | 农业工程学报2001，17，2： | 65 |
| 3 | A community-derived classification for extant lycophytes and ferns显示文摘发展史长通知了蕨类植物分类。当我们推断进化的树的能力改善了,针对认出生来的组的分类变得逐渐地预兆、稳定。这里,我们为 lycophytes 和蕨纲植物提供一个现代、全面分类,在下面,利用一条基于社区的途径类水平。我们 monophyly 用作主要标准让 taxa,而且目的识别保存两个广泛地被接受的存在 taxa 和界限并且与我们蕨类植物发展史的理解一致。总共,这个分类对待一在 337 个类, 51 个家庭, 14 目,和二个班估计了 11 916 种类。这个分类没在 lycophyte 和蕨纲植物上作为最后的词被打算分类,而是当前的假设的概括陈述,源于最好的可得到的数据并且在问题由熟悉植物的那些大多数塑造了。我们希望它将在蕨类植物上为最近的文学的那些想要的参考用作一个资源发展史和分类,为指导未来调查的一个框架,和推进讲话的刺激。 | Eric Schuettpelz Harald Schneider Alan R. Smith Peter Hovenkamp Jefferson Prado Germinal Rouhan Alexandre Salino Michael Sundue Thafs Elias Almeida Barbara Parris Emily B. Sessa Ashley R. Field Andre Luis de Gasper Carl J. Rothfels Michael D. Windham Marcus Lehnert Benjamin Dauphin Atsushi Ebihara Samuli Lehtonen Pedro Bond Schwartsburd Jordan Metzgar Li-Bing Zhang Li-Yaung Kuo Patrick J. Brownsey Masahiro Kato Marcelo Daniel Arana Francine C. Assis Michael S. Barker David S. Barrington Ho-Ming Chang Yi-Han Chang Yi-Shan Chao Cheng-Wei Chen De-Kui Chen Wen-Liang Chiou Vinicius Antonio de Oliveira Dittrich Yi-Fan Duan Jean-Yves Dubuisson Donald R. Farrar Susan Fawcett Jose Maria Gabriel y Galan Luiz Armando de Araujo Goes-Neto Jason R. Grant Amanda L. Grusz Christopher Haufler Warren Hauk Hai He Sabine Hennequin Regina Yoshie Hirai Layne Huiet Michael Kessler Petra Korall Paulo H. Labiak Anders Larsson Blanca Leen Chun-Xiang Li Fay-Wei Li Melanie Link-Perez Hong-Mei Liu Ngan Thi Lu Esteban I. Meza-Torres Xin-Yuan Miao Robbin Moran Claudine Massi Mynssens Nathalie Nagalingum Benjamin Ollgaard Alison M. Paul Jovani B. de S. Pereira Leon R. Perrie Monica Ponce Tom A. Ranker Christian Schulz Wataru Shinohara Alexander Shmakov Erin M. Sigel Filipe Soares de Souza Lana da Silva Sylvestre Weston Testo Luz Amparo Triana-Moreno Chie Tsutsumi Hanna Tuomisto IvAn A. Valdespino Alejandra Vasco Raquel Stauffer Viveros Alan Weakley Ran Wei Stina Weststrand Paul G. Wolf George Yatskievych Xiao-Gang Xu Yue-Hong Yan Liang Zhang Xian-Chun Zhang Xin-Mao Zhou | 2016 | Journal of Systematics and Evolution2016，54，6： | 44 |
| 4 | Bone Morphogenetic Protein (BMP) signaling in development and human diseases显示文摘Bone Morphogenetic Proteins(BMPs)are a group of signaling molecules that belongs to the Transforming Growth Factor-b(TGF-b)superfamily of proteins.Initially discovered for their ability to induce bone formation,BMPs are now known to play crucial roles in all organ systems.BMPs are important in embryogenesis and development,and also in maintenance of adult tissue homeostasis.Mouse knockout models of various components of the BMP signaling pathway result in embryonic lethality or marked defects,highlighting the essential functions of BMPs.In this review,we first outline the basic aspects of BMP signaling and then focus on genetically manipulated mouse knockout models that have helped elucidate the role of BMPs in development.A significant portion of this review is devoted to the prominent human pathologies associated with dysregulated BMP signaling. | Richard N.Wang Jordan Green Zhongliang Wang Youlin Deng Min Qiao Michael Peabody Qian Zhang Jixing Ye Zhengjian Yan Sahitya Denduluri Olumuyiwa Idowu Melissa Li Christine Shen Alan Hu Rex C.Haydon Richard Kang James Mok Michael J.Lee Hue L.Luu Lewis L.Shi | 2014 | Genes & Diseases2014，1，1： | 47 |
| 5 | Inflammatory bowel disease and cancer: The role of inflammation, immunosuppression, and cancer treatment显示文摘In patients with inflammatory bowel disease(IBD), chronic inflammation is a major risk factor for the development of gastrointestinal malignancies. The pathogenesis of colitis-associated cancer is distinct from sporadic colorectal carcinoma and the critical molecular mechanisms underlying this process have yet to be elucidated. Patients with IBD have also been shown to be at increased risk of developing extra-intestinal malignancies. Medical therapies that diminish the mucosal inflammatory response represent the foundation of treatment in IBD, and recent evidence supports their introduction earlier in the disease course. However, therapies that alter the immune system, often used for long durations, may also promote carcinogenesis. As the population of patients with IBD grows older, with longer duration of chronic inflammation and longer exposure to immunosuppression, there is an increasing risk of cancer development. Many of these patients will require cancer treatment, including chemotherapy, radiation, hormonal therapy, and surgery. Many patients will require further treatment for their IBD. This review seeks to explore the characteristics and risks of cancer in patients with IBD, and to evaluate the limited data on patients with IBD and cancer, including management of IBD after a diagnosis of cancer, the effects of cancer treatment on IBD, and the effect of IBD and medications for IBD on cancer outcomes. | Jordan E Axelrad Simon Lichtiger Vijay Yajnik | 2016 | World Journal of Gastroenterology2016，22，20： | 33 |
| 6 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 7 | Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and a major cause of cancer-related mortality for which liver resection is an important curative-intent treatment option. However, many patients present with advanced disease and with underlying chronic liver disease and/or cirrhosis, limiting the proportion of patients who are surgical candidates. In addition, the development of recurrent or de novo cancers following surgical resection is common. These issues have led investigators to evaluate the benefit of neoadjuvant and adjuvant treatment strategies aimed at improving resectability rates and decreasing recurrence rates. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC. In this review, we evaluate the evidence for various neoadjuvant and adjuvant therapies and discuss opportunities for future clinical and translational research. | Clifford Akateh Sylvester M Black Lanla Conteh Eric D Miller Anne Noonan Eric Elliott Timothy M Pawlik Allan Tsung Jordan M Cloyd | 2019 | World Journal of Gastroenterology2019，25，28： | 16 |
| 8 | Duodenal adenocarcinoma: Advances in diagnosis and surgical management显示文摘Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma(DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticoduodenectomy or segmental duodenal resection; either are acceptable options as long as negative margins are achievable and an adequate lymphadenectomy can be performed. Adjuvant chemotherapy and radiation are important components of multi-modality treatment for patients at high risk of recurrence. Further research would benefit from multiinstitutional trials that do not combine DA with other periampullary or small bowel malignancies. The purpose of this article is to perform a comprehensive review of DA with special focus on the surgical management and principles. | Jordan M Cloyd Elizabeth George Brendan C Visser | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 13 |
| 9 | A worldwide phylogenetic (Gramineae) II: An update classifications classification of the Poaceae and a comparison of two 2015显示文摘我们在场在 768 个类, 12 个亚科,七 supertribes, 52 个部落,五 supersubtribes,和 90 subtribes 的 11506 草种类的一个新全球种系发生的分类;并且比较在 2015 出版的草家庭的二个种系发生的分类(Soreng 等。并且凯洛格) 。亚科(在基于种的数字下顺序) 是有在 202 个类, 15 个部落,和 30 subtribes 的 3968 种类的 Pooideae;有在 247 个类, 13 个部落,和 19 subtribes 的 3241 种类的 Panicoideae;有在 125 个类,三个部落,和 15 subtribes 的 1670 种类的 Bambusoideae;有在 124 个类,五个部落,和 26 subtribes 的 1602 种类的 Chloridoideae;有在三个类的 367 种类的 Aristidoideae,和一个部落;有在 19 个类的 292 种类的 Danthonioideae,和一个部落;有在八个类的 184 种类的 Micrairoideae,和三个部落;有在 19 个类,四个部落,和二 subtribes 的 115 种类的 Oryzoideae;有在 14 个类,二个部落,和二 subtribes 的 40 种类的 Arundinoideae;有在三个类的 12 种类的 Pharoideae,和一个部落;有在二个类的 11 种类的 Puelioideae,和二个部落;并且有在二个类的四种的 Anomochlooideae,和二个部落。我们也包括在 subtribes,部落,和亚科之中说明层次关系的一棵光线的树。最新描述的 taxa 包括:supertribes Melicodae 和 Nardodae;supersubtribes Agrostidodinae, Boutelouodinae, Gouiniodinae, Loliodinae,和 Poodinae;并且 subtribes Echinopogoninae 和 Ventenatinae。 | Robert J. Soreng Paul M. Peterson Konstantin Romaschenko Gerrit Davidse Jordan K. Teisher Lynn G. Clark Patricia Barbera Lynn J. Gillespie Fernando O. Zuloaga | 2017 | Journal of Systematics and Evolution2017，55，4： | 11 |
| 10 | Non-functional neuroendocrine tumors of the pancreas: Advances in diagnosis and management显示文摘Nonfunctional neuroendocrine tumors of the pancreas(NF-PNETs) are a heterogeneous group of neoplasms. Although rare, the incidence of NF-PNETs is increasing significantly. The classification of PNETs has evolved over the past decades and is now based on a proliferation grading system. While most NF-PNETs are slow growing, tumors with more aggressive biology may becomeincurable once they progress to unresectable metastatic disease. Tumors of higher grade can be suspected preoperatively based on the presence of calcifications, hypoenhancement on arterial phase computed tomography, positron emission technology avidity and lack of octreotide scan uptake. Surgery is the only curative treatment and is recommended for most patients for whom complete resection is possible. Liver-directed therapies(thermal ablation, transarterial embolization) can be useful in controlling unresectable hepatic metastatic disease. In the presence of unresectable progressive disease, somatostatin analogues, everolimus and sunitinib can prolong progression-free survival. This article provides a comprehensive review of NF-PNETs with special emphasis on recent advances in diagnosis and management. | Jordan M Cloyd George A Poultsides | 2015 | World Journal of Gastroenterology2015，21，32： | 11 |
| 11 | Exploring and Exploiting Pan-genomics for Crop Improvement显示文摘Genetic variation ranging from single-nucleotide polymorphisms to large structural variants (SVs) can cause variation of gene content among individuals within the same species. There is an increasing appreciation that a single reference genome is insufficient to capture the full landscape of genetic diversity of a species. Pan-genome analysis offers a platform to evaluate the genetic diversity of a species via investigation of its entire genome repertoire. Although a recent wave of pan-genomic studies has shed new light on crop diversity and improvement using advanced sequencing technology, the potential applications of crop pan-genomics in crop improvement are yet to be fully exploited. In this review, we highlight the progress achieved in understanding crop pan?genomics, discuss biological activities that cause SVs, review important agronomical traits affected by SVs, and present our perspective on the application of pan-genomics in crop improvement. | Yongfu Tao Xianrong Zhao Emma Mace Robert Henry David Jordan | 2019 | Molecular Plant2019，12，2： | 10 |
| 12 | Multifaceted signaling regulators of chondrogenesis:Implications in cartilage regeneration and tissue engineering显示文摘Defects of articular cartilage present a unique clinical challenge due to its poor self-healing capacity and avascular nature.Current surgical treatment options do not ensure consistent regeneration of hyaline cartilage in favor of fibrous tissue.Here,we review the current understanding of the most important biological regulators of chondrogenesis and their interactions,to provide insight into potential applications for cartilage tissue engineering.These include various signaling pathways,including fibroblast growth factors(FGFs),transforming growth factor b(TGF-b)/bone morphogenic proteins(BMPs),Wnt/b-catenin,Hedgehog,Notch,hypoxia,and angiogenic signaling pathways.Transcriptional and epigenetic regulation of chondrogenesis will also be discussed.Advances in our understanding of these signaling pathways have led to promising advances in cartilage regeneration and tissue engineering. | Jordan D.Green Viktor Tollemar Mark Dougherty Zhengjian Yan Liangjun Yin Jixing Ye Zachary Collier Maryam K.Mohammed Rex C.Haydon Hue H.Luu Richard Kang Michael J.Lee Sherwin H.Ho Tong-Chuan He Lewis L.Shi Aravind Athiviraham | 2015 | Genes & Diseases2015，2，4： | 9 |
| 13 | 美国医学教育中的职业化问题:从证据到责任显示文摘职业化是维护公众对医学职业信任的核心要素,也是医患关系的本质所在。但有证据表明,公众对医学职业的信任日渐消失,医生也在维护医学职业价值观念时面临着各种挑战。本文在医学教育背景下界定“职业化”的定义和框架,描述了职业化面临的各种挑战,也详细论述了医学院校和教学医院在维护医学职业化过程中的角色和作用。此外,还评述了现行和试行中的评价职业化的工具、方法。最后,作者还提出一些建议供医学院校和教学医院参考。 | Jordan J Cohen 魏芬(编译) 梅人朗(审校) | 2007 | 复旦教育论坛2007，5，1： | 9 |
| 14 | 证据指导临床决策显示文摘澳大利亚循证护理中心(Joanna Briggs Institute,JBI)建立于1996年,为国际性循证实践合作机构,主要致力于护理及医学相关科学领域的研究。JBI目前在全球31个国家中设立有分中心,其中包括美国、英国、加拿大、西班牙、瑞典、南非、泰国、新西兰等,上海复旦大学护理学院在2004年11月成立了复旦大学循证护理中心,是JBI的第21个分中心。JBI志立于为广大医护专业人员提供最佳证据并促进其投入临床实践,成立12年来开展了系统、丰富的循证护理学术活动。包括组织进行专题的文献系统回顾、举办“循证护理”国际年会、举行培训和研讨会、开展根据文献系统回顾引出的相关研究、资助培训“循证护理”实践活动、编辑发行((BestPractice:EvidenceBasedPracticeInformationSheets)(《最佳护理实践》)刊物,为临床护理实践提供实证,以倡导循证护理在实践中的作用。目前JBI已公开发表的循证护理专题成果有36项,例如:“压疮的危险因素评估和预防”、“压疮所致组织损伤的处理”、“外周血管插管装置的管理和感染控制”、“医院跌倒和坠床的预防和处理”、“癌症化疗病人口腔溃疡的预防和处理”、“冠心病患者的心理社会干预”、“手术病人的术前教育”、“急性疼痛的非药物干预法”等等。JBI通过组织世界各地的专题小组进行为期至少半年的文献系统回顾,总结归纳实证依据,并开展相应研究,发布专题刊物,对循证护理在全球的推广,进而提高护理实践的科学性和有效性发挥了重要的作用。本刊将通过此栏目陆续发表JBI提供的部分《最佳护理实践》的中文译文,以便更好地将循证护理的理念和最新成果提供给广大的护理工作者,促进临床护理的规范性和科学性。《证据指导临床决策》是在本栏目发表的第一篇文章,文中介绍了:何谓证据、循证实践,及JBI循证实践的模式。 | Jordan Zoe Court Anthea Xue Yi-fan | 2009 | 中华护理杂志2009，44，4： | 8 |
| 15 | 非营利组织的社会企业化:模式与策略显示文摘1980年代至今,受到社会福利社会化以及新自由主义思潮在公共部门的影响,中国的非营利部门与西方一样深受市场因素影响,社会企业这种新型组织形态也在我国非营利部门兴起。根据Alter的类型划分,分析了我国福利领域非营利组织社会企业化模式及其影响因素,探讨了社会企业平衡经济与社会双重目标的策略选择。基于一个对运作社会企业项目的NPO组织的小型调查和两家NPO组织的深度访谈,本文认为,服务收费模式和雇佣就业模式为当前社会福利领域非营利组织较为普遍的社会企业化模式,为机构企业化运作背后之动力,满足社会需要、缓解财政压力与提升社会影响力。交叉补贴,多元化,快速扩张与治理保障是机构平衡双重目标之策略。 | 田蓉 Lucy Jordan | 2016 | 华东理工大学学报(社会科学版)2016，31，4： | 8 |
| 16 | Neoadjuvant treatment strategies for intrahepatic cholangiocarcinoma显示文摘Intrahepatic cholangiocarcinoma(ICC)is the second most common primary liver malignancy and is increasing in incidence.Long-term outcomes are optimized when patients undergo margin-negative resection followed by adjuvant chemotherapy.Unfortunately,a significant proportion of patients present with locally advanced,unresectable disease.Furthermore,recurrence rates are high even among patients who undergo surgical resection.The delivery of systemic and/or liver-directed therapies prior to surgery may increase the proportion of patients who are eligible for surgery and reduce recurrence rates by prioritizing early systemic therapy for this aggressive cancer.Nevertheless,the available evidence for neoadjuvant therapy in ICC is currently limited yet recent advances in liver directed therapies,chemotherapy regimens,and targeted therapies have generated increasing interest its role.In this article,we review the rationale for,current evidence for,and ongoing research efforts in the use of neoadjuvant therapy for ICC. | Clifford Akateh Aslam M Ejaz Timothy Michael Pawlik Jordan M Cloyd | 2020 | World Journal of Hepatology2020，12，10： | 8 |
| 17 | 可操作性地震预报:有关“为什么”和“怎么办”的几点思考显示文摘假设研究都市区附近断层的地震学家根据经验知识以令人信服的口吻声称,未来一周内发生一次大地震的概率要比平常的一个7天周期中发生地震的概率高出100~1000倍,那么——如果采取行动的话——民众应该采取那些防御措施呢? | Thomas H Jordan Lucile M Jones 左玉玲(译) 郑需要(校) | 2010 | 国际地震动态2010，，10： | 7 |
| 18 | An overview of separation by magnetically stabilized beds:State-of-the-art and potential applications显示文摘This article deals with problems relevant to implementation of magnetically stabilized beds (MSB) as separation devices. The main issues discussed are: bed mechanics, bed structure, possibilities to create controllable filter media, etc. As examples several separation techniques are discussed: dust filtration—magnetic and non-magnetic, ion-exchange, copper cementation, yeast filtration from biological liquids, particle separation by density and magnetic properties, dangerous wastes removal. Only key publications will be quoted that provide a basis for further reading and study and relevant information. | Jordan Hristov Ludmil Fachikov | 2007 | China Particuology2007，5，1： | 6 |
| 19 | Transcranial magnetic stimulation: potential treatment for co-occurring alcohol, traumatic brain injury and posttraumatic stress disorders显示文摘Alcohol use disorder(AUD), mild traumatic brain injury(m TBI), and posttraumatic stress disorder(PTSD) commonly co-occur(AUD + m TBI + PTSD). These conditions have overlapping symptoms which are, in part, reflective of overlapping neuropathology. These conditions become problematic because their co-occurrence can exacerbate symptoms. Therefore, treatments must be developed that are inclusive to all three conditions. Repetitive transcranial magnetic stimulation(r TMS) is non-invasive and may be an ideal treatment for co-occurring AUD + m TBI + PTSD. There is accumulating evidence on r TMS as a treatment for people with AUD, m TBI, and PTSD each alone. However, there are no published studies to date on r TMS as a treatment for co-occurring AUD + m TBI + PTSD. This review article advances the knowledge base for r TMS as a treatment for AUD + m TBI + PTSD. This review provides background information about these co-occurring conditions as well as r TMS. The existing literature on r TMS as a treatment for people with AUD, TBI, and PTSD each alone is reviewed. Finally, neurobiological findings in support of a theoretical model are discussed to inform TMS as a treatment for co-occurring AUD + m TBI + PTSD. The peer-reviewed literature was identified by targeted literature searches using Pub Med and supplemented by cross-referencing the bibliographies of relevant review articles. The existing evidence on r TMS as a treatment for these conditions in isolation, coupled with the overlapping neuropathology and symptomology of these conditions, suggests that r TMS may be well suited for the treatment of these conditions together. | Amy A.Herrold Sandra L.Kletzel Brett C.Harton R.Andrew Chambers Neil Jordan Theresa Louise-Bender Pape | 2014 | Neural Regeneration Research2014，9，19： | 6 |
| 20 | Inactivation of Mitochondrial Complex Ⅰ Induces the Expression of a Twin Cysteine Protein that Targets and Affects Cytosolic, Chloroplastidic and Mitochondrial Function显示文摘At12Cys-1 (At5g64400 ) 和 At12Cys-2 (At5g09570 ) 是二密切相关的 isogenes 编码小、成双的半胱氨酸蛋白质,典型地在线粒体定位了。At12Cys-2 抄本与破坏 mitochondrial 蛋白质,而是 At12Cys 的增加在许多异种被导致蛋白质仅仅与减少的 mitochondrial 在异种被检测复杂我丰富。在缺乏 mitochondrial 建筑群的异种的 At12Cys 蛋白质感应我被位于线粒体,叶绿体,和 cytosol 的 At12Cys 蛋白质伴随。生物化学的分析揭示了那甚至单个的基因删除,即, At12cys-1 或 At12cys-2,在 mitochondrial 和叶绿体功能上有效果。然而,仅仅加倍异种,即, At12cys-1 : At12cys-2,影响许多蛋白质和 mRNA 抄本编码翻译延伸因素以及 rRNA 丰富。蓝本国的页证明 At12Cys 与 mitochondrial supercomplex 共同移居我 + III。同样, At12cys-1 和 At12cys-2 基因的删除,然而并非单个基因删除,导致提高的忍耐到干旱和轻应力和增加的抗氧化剂能力。正式就职和在在建筑群的减小之上的 At12Cys 的多重本地化我丰富提供机制明确地表明 mitochondrial 机能障碍到 cytosol 然后在以外到在房间的另外的细胞器。 | Yan Wang Wenhui Lyu Oliver Berkowitz Jordan D. Radomiljac Simon R. Law Monika W. Murcha Chris Carrie Pedro F. Teixeira Beata Kmiec Owen Duncan Olivier Van Aken Reena Narsai Elzbieta Glaser Shaobai Huang Ute Roessner A. Harvey Millar James Whelan | 2016 | Molecular Plant2016，9，5： | 5 |
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