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| 1 | Postoperative deep shoulder infections following rotator cuff repair显示文摘Rotator cuff repair(RCR) is one of the most commonly performed surgical procedures in orthopaedic surgery. The reported incidence of deep soft-tissue infections after RCR ranges between 0.3% and 1.9%. Deep shoulder infection after RCR appears uncommon, but the actual incidence may be higher as many cases may go unreported. Clinical presentation may include increasing shoulder pain and stiffness, high temperature, local erythema, swelling, warmth, and fibrinous exudate. Generalized fatigue and signs of sepsis may be present in severe cases. Varying clinical presentation coupled with a low index of suspicion may result in delayed diagnosis. Laboratory findings include high erythrocyte sedimentation rate and C-reactive protein level, and, rarely, abnormal peripheral blood leucocyte count. Aspiration of glenohumeral joint synovial fluid with analysis of cell count, gram staining and culture should be performed in all patients suspected with deep shoulder infection after RCR. The most commonly isolated pathogens are Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. Management of a deep soft-tissue infection of the shoulder after RCR involves surgical debridement with lavage and long-term intravenous antibiotic treatment based on the pathogen identified. Although deep shoulder infection after RCR is usually successfully treated, complications of this condition can be devastating. Prolonged course of intravenous antibiotic treatment, extensive soft-tissue destruction and adhesions may result in substantially diminished functional outcomes. | Kivanc Atesok Peter MacDonald Jeff Leiter Sheila McRae Greg Stranges Jason Old | 2017 | World Journal of Orthopedics2017，8，8： | 3 |
| 2 | Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study显示文摘 | Sten Nilsson Lars Franzén Christopher Parker Christopher Tyrrell René Blom Jan Tennvall Bo Lennern?s Ulf Petersson Dag C Johannessen Michael Sokal Katharine Pigott Jeffrey Yachnin Michael Garkavij Peter Strang Johan Harmenberg Bj?rg Bolstad ?yvind S Brula | 2007 | Lancet Oncology2007，，7： | 1 |
| 3 | Attenuation of homocysteine-induced endothelial dysfunction by exercise training显示文摘 | Reid Hayward Ratree Ruangthai Peter Karnilaw Adam Chicco Robert Strange Heidi McCarty Kim C. Westerlind | 2003 | Pathophysiology2003，，： | 1 |
| 4 | Breakthrough pain in malignant and non-malignant diseases: a review of prevalence, characteristics and mechanisms显示文摘 | Kristina B. Svendsen Steen Andersen Sigurdur Arnason Staffan Arnér Harald Breivik Tarja Heiskanen Eija Kalso Ulf E. Kongsgaard Per Sjogren Peter Strang Flemming W. Bach Troels S. Jensen | 2004 | European Journal of Pain2004，，2： | 1 |
| 5 | Impact of body fat changes in mediating the effects of antiretroviral therapy on blood pressure in HIV-infected persons in a sub-Saharan African setting显示文摘Background:Previous studies of HIV-infected patients have shown significant associations between highly active antiretroviral therapy(HAART)and increased blood pressure;however,the mechanisms involved are less clear.Therefore,we sought to investigate the potential impact of body fat changes in mediating the effects of HAART on blood pressure changes among people living with HIV.Methods:Four hundred six consenting patients(≥18 years of age)attending a tertiary HIV clinic in semi-urban Nigeria were recruited between August and November 2014 as part of a cross-sectional study.We performed bias-corrected bootstrap tests of mediation using 95%confidence intervals(CI)to determine the mediating effects of body mass index and waist circumference(mediators)on the total effects of HAART exposure(primary predictor)on blood pressure(outcome),while controlling for age,sex and other potential confounders.Results:Waist circumference remained a significant partial mediator of the total effects of HAART exposure on increasing systolic blood pressure(coefficient:1.01,95%CI:0.33 to 2.52,11%mediated)and diastolic blood pressure(coefficient:0.68,95%CI:0.26 to 1.89,9%mediated)after adjusting for age,sex,smoking status,CD4 count and duration of HIV infection.No significant mediating effect was observed with body mass index alone or in combination with waist circumference after adjusting for all potential confounders.Conclusion:Waist circumference significantly mediates the effects of HAART on blood pressure in persons living with HIV,independent of the role of traditional risk factors.The use of waist circumference as a complementary body fat measure to body mass index may improve the clinical prediction of hypertension in HIV-infected patients on antiretroviral therapy. | Chidozie U.Nduka Olalekan A.Uthman Peter K.Kimani Abraham O.Malu Saverio Stranges | 2016 | Infectious Diseases of Poverty2016，5，1： | 1 |
| 6 | Breakthrough pain in malignant and non-malignant diseases: a review of prevalence, characteristics and mechanisms显示文摘 | Kristina B. Svendsen Steen Andersen Sigurdur Arnason Staffan Arnér Harald Breivik Tarja Heiskanen Eija Kalso Ulf E. Kongsgaard Per Sjogren Peter Strang Flemming W. Bach Troels S. Jensen | 2004 | European Journal of Pain2004，，2： | 1 |
| 7 | The application of multiwavelet filterbanks to image processing显示文摘 | Peter Niels Gilbert Strang | 1999 | IEEE Trans On Image Processing1999，8，4： | 1 |
| 8 | The application of multiwavelet filterbanks to image processing显示文摘 | Vasily Strela Peter Niels Heller Gilbert Strang | 1999 | IEEE Transactions on Image Processing1999，8，： | 1 |
| 9 | Assessment of patient capacity to consent to treatment显示文摘 | Dr. Edward Etchells MD MSc Peteris Darzins PhD Michel Silberfeld MD Peter A. Singer MD MPH Julia McKenny RN Gary Naglie MD Mark Katz MD Gordon H. Guyatt MD D. William Molloy MB David Strang MD | 1999 | Journal of General Internal Medicine1999，，1： | 1 |
| 10 | Association between functional polymorphism in EGF gene and malignant melanoma显示文摘 | Majid Shahbazi Vera Pravica Najma Nasreen Hana Fakhoury Anthony A Fryer Richard C Strange Peter E Hutchinson Joy E Osborne John T Lear Andrew G Smith Ian V Hutchinson | 2002 | The Lancet . 2002 (9304)2002，，9304： | 1 |
| 11 | Breakthrough pain in malignant and non-malignant diseases: a review of prevalence, characteristics and mechanisms显示文摘 | Kristina B. Svendsen Steen Andersen Sigurdur Arnason Staffan Arnér Harald Breivik Tarja Heiskanen Eija Kalso Ulf E. Kongsgaard Per Sjogren Peter Strang Flemming W. Bach Troels S. Jensen | 2004 | European Journal of Pain2004，，2： | 1 |
| 12 | The application of muhiwavelet fiherbanks to image processing显示文摘 | Vasily Strela Peter Niels Gilbert Strang | 1999 | IEEE Trans On Image Processing1999，8，4： | 1 |
| 13 | The Application of Multiwavelet Filterbanks to Image Processing显示文摘 | Vasily Stria Peter Niels Heller Gilbert Strang | 1999 | IEEE Transactions on Image Processing1999，8，4： | 1 |
| 14 | Death anxiety in brain tumor patients and their spouses显示文摘 | Susan Adelbratt Peter Strang | 2000 | Palliative Medicine2000，14，： | 1 |
| 15 | Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction显示文摘 | Jonathon Habersberger Frederik Strang Amelie Scheichl Nay Htun Nicole Bassler Ruusu-Maaria Merivirta Philipp Diehl Guy Krippner Peter Meikle Steffen U. Eisenhardt Ian Meredith Karlheinz Peter | 2012 | Cardiovascular Research2012，，1： | 1 |
| 16 | Statin, testosterone and phosphodiesterase 5-inhibitor treatments and age related mortality in diabetes显示文摘AIM To determine how statins, testosterone(T) replacement therapy(TRT) and phosphodiesterase 5-inhibitors(PDE5I) influence age related mortality in diabetic men.METHODS We studied 857 diabetic men screened for the BLAST study, stratifying them(mean follow-up = 3.8 years) into:(1) Normal T levels/untreated(total T > 12 nmol/L and free T > 0.25 nmol/L), Low T/untreated and Low T/treated;(2) PDE5I/untreated and PDE5I/treated; and(3) statin/untreated and statin/treated groups. The relationship between age and mortality, alone and with T/TRT, statin and PDE5 I treatment was studied using logistic regression. Mortality probability and 95%CI were calculated from the above models for each individual. RESULTS Age was associated with mortality(logistic regression, OR = 1.10, 95%CI: 1.08-1.13, P < 0.001). With all factors included, age(OR = 1.08, 95%CI: 1.06-1.11, P < 0.001), Low T/treated(OR = 0.38, 95%CI: 0.15-0.92, P = 0.033), PDE5I/treated(OR = 0.17, 95%CI: 0.053-0.56, P = 0.004) and statin/treated(OR = 0.59, 95%CI: 0.36-0.97, P = 0.038) were associated with lower mortality. Age related mortality was as described by Gompertz, r2 = 0.881 when Ln(mortality) was plotted against age. The probability of mortality and 95%CI(from logistic regression) of individuals, treated/untreated with the drugs, alone and in combination was plotted against age. Overlap of 95%CI lines was evident with statins and TRT. No overlap was evident with PDE5 I alone and with statins and TRT, this suggesting a change in the relationship between age and mortality. CONCLUSION We show that statins, PDE5 I and TRT reduce mortality in diabetes. PDE5 I, alone and with the other treatments significantly alter age related mortality in diabetic men. | Geoffrey Hackett Peter W Jones Richard C Strange Sudarshan Ramachandran | 2017 | World Journal of Diabetes2017，8，3： | 0 |
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