|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 手术期间化学疗法与单独手术治疗可切除的胃食管癌疗效比较显示文摘 | Cunningham D Allum WH Stenning SP 菅鑫妍 | 2006 | 中国处方药2006，5，8： | 432 |
| 2 | 围手术期化疗与单纯手术治疗可切除性胃食管癌的比较 | Cunningham D. Allum W.H. Stenning S.P. 程金湘 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，0，12： | 47 |
| 3 | DNA疫苗接种的免疫学机理、优越性及安全性显示文摘本文介绍了DNA免疫接种的免疫学机理、优点及安全性问题等.鉴于DNA免疫接种是一门新兴的技术,目前尚未完成安全性和长期效果观察,故在考虑实际应用推广时,应全面权衡本法的效益和危险性问题. | 周光前 Sten Hammarstrm | 1997 | 国外医学(预防.诊断.治疗用生物制品分册)1997，20，2： | 16 |
| 4 | Clinical Study on 136 Children with Sudden Sensorineural Hearing Loss显示文摘 | Feng-Jiao Li Da-Yong Wang Hong-Yang Wang Li Wang Feng-Bo Yang Lan Lan Jing Guan Zi-Fang Yin UII Rosenhall Lan Yu Sten Hellstrom Xi-Jun Xu Mao-Li Duan Qiu-Ju Wang | 2016 | Chinese Medical Journal2016，，8： | 15 |
| 5 | 应用BED-CEIA检测干血斑样本监测HIV-1发病率的可行性研究显示文摘目的研究干血斑样本应用于现场HIV-1BED—CEIA新近感染的检测以及监测HIV-1发病率的可行性。方法收集27个自愿咨询检测(VCT)哨点的10313名咨询者的血浆和干血斑样本,进行HIV抗体检测,对经免疫印迹方法确认的349例HIV感染者的血浆和干血斑样本同时进行BED—CEIA检测,检验干血斑样本BED—CEIA新近感染检测结果的稳定性和重复性,比较两种样本检测结果的差异及对HIV发病率估计的一致性。结果应用干血斑样本检测具有较好的稳定性和重复性,R^2值分别达到0.9551和0.95。349对样本的检测结果显示,294对样本被同时判定为长期感染,53对样本被同时判定为新近感染,两种样本对HIV-1是否为新近感染判断的一致性达到99.43%。而2对样本得到不同的结果,其An值均处于临界值附近。在人群总体水平上,两种样本计算得到的HIV-1发病率完全一致。结论在HIV-1BED—CEIA新近感染检测中,尽管个别样本检测结果存在差异,但在人群水平上十血斑样本的检测结果对HIV-1发病率的估计与血浆样本没有差异,因此在中国可以应用干血斑样本进行HIV-1BED-CEIA新近感染检测。 | 沈圣 田飞 江华洲 孙国清 缪礼锋 郭晓黎 肖瑶 贾玉江 Sten H.Vermund 蒋岩 | 2009 | 中华流行病学杂志2009，30，3： | 12 |
| 6 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 7 | 中国纸制品消费趋势:城市化增长的效应分析和预测显示文摘基于对近期未来的人口—经济增长的预测,分析了城市化增长对未来纸制品消费的影响。用'自相关误差回归'的方法检验人口和城市化增长的不同发展路径对于纸制品消费的影响。中国的城市化过程对纸制品消费影响很大,更快的城市化进程,相应的影响会更强烈。比较人口变量和经济变量,城市家庭经济因素相对更加明显。在近期的未来,随着纸制品消费的增加,其对环境污染的压力也会增大。 | 曹桂英 郑晓瑛 Joanna Horabik Sten Nilsson 徐晋涛 王海东 王灏晨 | 2011 | 人口与发展2011，17，2： | 5 |
| 8 | Evaluating the Ryman-Laikre effect for marine stock enhancement and aquaculture显示文摘 | Robin S. WAPLES Kjetil HINDAR Sten KARLSSON Jeffrey J. HARD | 2016 | Current Zoology2016，62，6： | 5 |
| 9 | Experimental and Numerical Investigation of Centrifugal Pumps with Asymmetric Inflow Conditions显示文摘Most of the times pumps operate off best point states.Reasons are changes of operating conditions,modifications,pollution and wearout or erosion.As consequences non-rotational symmetric flows,transient operational conditions,increased risk of cavitation,decrease of efficiency and unpredictable wearout can appear.Especially construction components of centrifugal pumps,in particular intake elbows,contribute to this matter.Intake elbows causes additional losses and secondary flows,hence non-rotational velocity distributions as intake profile to the centrifugal pump.As a result the impeller vanes experience permanent changes of the intake flow angle and with it transient flow conditions in the blade channels.This paper presents the first results of a project,experimentally and numerically investigating the consequences of non-rotational inflow to leading edge flow conditions of a centrifugal pump.Therefore two pumpintake-elbow systems are compared,by only altering the intake elbow geometry:a common single bended 90°elbow and a numerically optimized elbow(improved regarding rotational symmetric inflow conditions and friction coefficient).The experiments are carried out,using time resolved stereoscopic PIV on a full acrylic pump with refractions index matched(RIM)working fluid.This allows transient investigations of the flow field simultaneously for all blade leading edges.Additional CFD results are validated and used to further support the investigation i.e.for comparing an analog pump system with ideal inflow conditions. | Sten Mittag Martin Gabi | 2015 | Journal of Thermal Science2015，24，6： | 5 |
| 10 | DNA疫苗接种研究的方法学问题显示文摘本文概述了DNA疫苗研制和接种方法的研究现状,包括质粒载体和抗原基因的选择、DNA疫苗接种途径等,并介绍了有关DNA免疫接种实验研究的十二步自我帮助程序,从而为初涉该领域的研究人员提供了捷径. | 周光前 Sten Hammarstrm | 1997 | 国外医学(预防.诊断.治疗用生物制品分册)1997，20，1： | 5 |
| 11 | Latest development of double perovskite electrode materials for solid oxide fuel cells:a review显示文摘Recently,the development and fabrication of electrode component of the solid oxide fuel cell(SOFC)have gained a significant importance,especially after the advent of electrode supported SOFCs.The function of the electrode involves the facilitation of fuel gas diffusion,oxidation of the fuel,transport of electrons,and transport of the byproduct of the electrochemical reaction.Impressive progress has been made in the development of alternative electrode materials with mixed conducting properties and a few of the other composite cermets.During the operation of a SOFC,it is necessary to avoid carburization and sulfidation problems.The present review focuses on the various aspects pertaining to a potential electrode material,the double perovskite,as an anode and cathode in the SOFC.More than 150 SOFCs electrode compositions which had been investigated in the literature have been analyzed.An evaluation has been performed in terms of phase,structure,diffraction pattern,electrical conductivity,and power density.Various methods adopted to determine the quality of electrode component have been provided in detail.This review comprises the literature values to suggest possible direction for future research. | Shammya AFROZE AfizulHakem KARIM Quentin CHEOK Sten ERIKSSON Abul K.AZAD | 2019 | Frontiers in Energy2019，13，4： | 5 |
| 12 | A public health approach to rapid scale-up of free antiretroviral treatment in China: an ounce of prevention is worth a pound of cure显示文摘 | Marc Bulterys Sten H. Vermund Ray Y. Chen Chin-Yih Ou | 2009 | Chinese Medical Journal2009，，11： | 4 |
| 13 | 运动过程的网络逻辑——从离子通道到动物行为显示文摘为了揭示神经网络在脊椎动物运动中所行使的内在功能,作者开发了七鳃鳗这种低等脊椎动物模型。在这套系统中,不仅可以了解到运动模式生成网络以及激活此网络的命令系统,同时还可以在运动中研究方向控制系统和变向控制系统。七鳃鳗的神经系统有较少的神经元,而且运动行为中的不同运动模式可以由分离的神经系统所引发。模式生成神经网络包括同侧的谷氨酸能中间神经元和对侧的抑制性甘氨酸能中间神经元。网络中的突触连接、细胞膜特性和神经递质都也已经被鉴定。运动是由脑干区域的网状脊髓神经元所引起,而这些神经元又是被间脑和中脑分离的一些运动命令神经元群所控制。因此,运动行为最初是由这两个'运动核心'所启动。而这两个运动核心被基底神经节调控,基底神经节即时地做出判断是否允许下游的运动程序启动。在静止情况下基底神经节的输出核团维持对下游不同运动核心的抑制作用,反之则去除抑制活化运动核心。纹状体和苍白球被认为是这个运动抉择系统的主要部件。根据'霍奇金-贺胥黎'模型神经元开发了这套网络模型,不同的细胞具有各自相应的不同亚型的钠、钾、钙离子通道和钙依赖的钾通道。每个模型神经元拥有86个不同区域模块以及其对应的生物学功能,例如频率控制、超极化等等。然后根据已有实验证据,利用突触将不同的模型神经元相连。而系统中的10000个神经元大致和生物学网络上的细胞数量相当。突触数量为760000。突触类型有AMPA、NMDA、glycine型。有了这样大规模的模型,不仅可以模拟肌节与肌节之间的神经网络,还可以模拟到由基底神经节开始的行为起始部分。此外,这些网络模拟还被用于一个神经机械学模型来模拟包含有推进和方向控制部分的真实运动。 | GRILLNER Sten | 2008 | 生命科学2008，20，5： | 3 |
| 14 | 水流程的分析:瑞典一个潜在地质埋藏点的研究方法和计算实例显示文摘与深处于基岩中的核废料地质埋藏点的选址有关的安全评估需要确定潜在的流程及起源于埋藏点深度的放射性核素的相关传播时间。利用瑞典Laxemar候选场所作为案例研究,本文描述了模拟方法、数据集成以及由此而产生的水流模型,重点放在第四纪沉积物和基岩的上部150m。实例模拟确定了到地下水排泄区的流程以及表层系统中的流程。大多数模拟的地下水流程都终止于主要的表层水域和海岸线,即便用于跟踪流径的颗粒是以一种在相对较浅深度的均匀的空间分布输入的。计算出来的决定放射性核素衰减和持留可用的时间的地下水到沿岸海湾的行进时间要长于到该场所其他生物圈目标的。此外,基于GIS的模拟如何能用于限制安全评估需要说明的地方流程在此也加以解释。根据这些结果,本文讨论了使目前的模型与深基岩地下水流模型相结合的方法。 | Kent Werner Emma Bosson Sten Berglund 林宝法(译) 胡恩和(校) | 2006 | AMBIO-人类环境杂志2006，35，8： | 3 |
| 15 | Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer显示文摘 | Cunningham D Allum WH Stenning SP | | New England Journal of Medicine0，，： | 2 |
| 16 | Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis显示文摘AIM To confirm previous conclusions on Saccharomyces cerevisiae(S. cerevisiae) CNCM I-3856 for irritable bowel syndrome(IBS) management.METHODS An individual patient data meta-analysis was performed on two randomized clinical trials studying the effect of S. cerevisiae CNCM I-3856 supplementation on gastrointestinal(GI) symptoms in IBS subjects. A total of 579 IBS subjects were included. Outcomes were the daily Likert scale scores of abdominal pain/discomfort and bloating [area under the curve(AUC) and weekly means], responder status, and bowel movements(stool frequency and consistency). Statistical analyses were conducted in Intent to Treat(ITT) population, IBS-C subjects and IBS-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline('IBS-C ≥ 2 subpopulation').RESULTS S. cerevisiae CNCM I-3856 significantly improved abdominal pain/discomfort and bloating during the second month of supplementation [AUC(W5-W8)]with improvement up to the minimal clinically relevant threshold of 10%: a 12.3% reduction of abdominal pain/discomfort in the ITT population compared to the Placebo group(P = 0.0134) has been observed. In the IBS-C ≥ 2 subpopulation, there were a 13.1% reduction of abdominal pain/discomfort and a 14.9% reduction of bloating compared to the Placebo group(P = 0.0194 and P = 0.0145, respectively). GI symptoms significantly decreased during supplementation but no statistical differences were reported between groups at the end of the supplementation period. Responder status was defined as a subject who experienced a decrease of 1 arbitrary unit(a.u.) or 50% of the abdominal discomfort score from baseline for at least 2 wk out of the last 4 wk of the study. A significant difference between groups was reported in the ITT population, when considering the first definition: subjects in the Active group had 1.510 higher odds to be a responder(reduction of 1 a.u. of abdominal pain/discomfort) compared with subjects in the Placebo group(P = 0.0240). At the end of supplementation period, stool consistency in the Active group of the ITT population was significantly improved and classified as 'normal' compared to Placebo(respectively 3.13 ± 1.197 a.u. vs 2.58 ± 1.020 a.u., P = 0.0003). Similar results were seen in the IBS-C ≥ 2 subpopulation(Active group: 3.14 ± 1.219 a.u. vs Placebo group: 2.59 ± 1.017 a.u., P = 0.0009).CONCLUSION This meta-analysis supports previous data linking S. cerevisiae I-3856 and improvement of GI symptoms, in IBS overall population and in the IBS-C and IBS-C ≥ 2 subpopulations. | Amélie Cayzeele-Decherf Fanny Pélerin Sébastien Leuillet Benoit Douillard Béatrice Housez Murielle Cazaubiel Gunnard K Jacobson Peter Jüsten Pierre Desreumaux | 2017 | World Journal of Gastroenterology2017，23，2： | 2 |
| 17 | Identifying the ‘unidentified’ fungi: a global-scale long-read third-generation sequencing approach显示文摘Molecular identification methods,in particular high-throughput sequencing tools,have greatly improved our knowledge about fungal diversity and biogeography,but many of the recovered taxa from natural environments cannot be identified to species or even higher taxonomic levels.This study addresses the phylogenetic placement of previously unrecognized fungal groups by using two complementary approaches:(i)third-generation amplicon sequencing analysis of DNA from global soil samples,screening out ITS reads of<90%similarity to other available Sanger sequences,and(ii)analysis of common fungal taxa that were previously indicated to be enigmatic in terms of taxonomic placement based on the ITS sequences alone(so-called top50 sequences).For the global soil samples,we chose to amplify the full rRNA gene operon using four partly overlapping amplicons and multiple newly developed primers or primer combinations that cover nearly all fungi and a vast majority of non-fungal eukaryotes.We extracted the rRNA 18S(SSU)and 28S(LSU)genes and performed phylogenetic analyses against carefully selected reference material.Both SSU and LSU analyses placed most soil sequences and top50 sequences to known orders and classes,but tens of monophyletic groups and single sequences remained outside described taxa.Furthermore,the LSU analyses recovered a few small groups of sequences that may potentially represent novel phyla.We conclude that rRNA genes-based phylogenetic analyses are efficient tools for determining phylogenetic relationships of fungal taxa that cannot be placed to any order or class using ITS sequences alone.However,in many instances,longer rRNA gene sequences and availability of both SSU and LSU reads are needed to improve taxonomic resolution.By leveraging third-generation sequencing from global soil samples,we successfully provided phylogenetic placement for many previously unidentified sequences and broadened our view on the fungal tree of life,with 10-20%new order-level taxa.In addition,the PacBio sequence data greatly extends fungal class-level information in reference databases. | Leho Tedersoo Sten Anslan Mohammad Bahram Urmas Kõljalg Kessy Abarenkov | 2020 | Fungal Diversity2020，，4： | 2 |
| 18 | Distinct pattern of age-specific incidence of Guillain-Barré syndrome in Harbin, China显示文摘 | Qi Cheng De-Sheng Wang Guo-Xin Jiang Hui Han Yan Zhang Wen-Zhi Wang Sten Fredrikson | 2002 | Journal of Neurology2002，，1： | 2 |
| 19 | Experimental Study of An Aquaculture Net Cage in Waves and Current显示文摘Model experiments of a floating fish cage subjected to waves and current have been performed. The objective was to study the dynamic behaviour of the fish cage model in waves and current. The fish cage model was composed of a model net, a flexible floating collar of the circular plastic type and a weight system. It was found that there are many wave periods in which cancellation of the wave-induced forces on the model occur. These cancellation wave periods are within the range of dimensioning wave periods commonly used for testing of fish farm structures and hence are important to be aware of. Large deformations of the net under realistic wave and current conditions were observed, where contact between the net and other parts of the structure were identified. This may cause damages to the net due to abrasion. | David KRISTIANSEN Pal LADER Фsten JENSEN David FREDRIKSSON | 2015 | China Ocean Engineering2015，29，3： | 2 |
| 20 | Angiostatin fragments in urine from patients with malignant disease显示文摘 | Sten Linder M Linder C Strander H | 1999 | Anticancer Res1999，19，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员