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| 1 | Frequency and Clinical Determinants of Poststroke Depression显示文摘 | Tarja Pohjasvaara Antero Leppavuori Irina Siira Risto Vataja Markku Kaste Timo Erkinjuntti | 1998 | Stroke: A Journal of Cerebral Circulation1998,,11: | 4 |
| 2 | Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis显示文摘AIM: To investigate efficacy and safety for granulocyte, monocyte apheresis in a population of pediatric patients with ulcerative colitis.METHODS: The ADAPT study was a prospective, openlabel, multicenter study in pediatric patients with moderate, active ulcerative colitis with pediatric ulcerative colitis activity index(PUCAI) of 35-64. Patients received one weekly apheresis with Adacolumn granulocyte, monocyte/macrophage adsorptive(GMA) apheresis over 5 consecutive weeks, optionally followed by up to 3 additional apheresis treatments over 3 consecutive weeks. The primary endpoint was the change in mean PUCAI between baseline and week 12; the secondary endpoint was improvement in PUCAI categorized as(Significant Improvement, PUCAI decrease of ≥ 35), Moderate Improvement(PUCAI decrease of 20 < 35), Small Improvement(PUCAI decrease of 10 < 20) or No change(PUCAI decrease of < 10). RESULTS: Twenty-five patients(mean age 13.5 years; mean weight 47.7 kg) were enrolled. In the intention-to-treat set(ITT), the mean value for PUCAI improvement was 22.3 [95%CI: 12.9-31.6; n = 21]. In the per-protocol(PP) set, the mean improvement was 36.3 [95%CI: 31.4-41.1; n = 8]. Significant Improvement was recorded for 9 out of 20 patients(45%); 5 out of 20 patients(25%) had Moderate Improvement and one patient(5%) had No Change in PUCAI score at week 12. In the PP set, six out of eight patients(75%) showed Significant Improvement; and in two out of eight patients(25%) Moderate Improvement was recorded. The endoscopic activity index(EAI) decreased by 3 points on average. Seven(7) out of 21(33%) patients in ITT and 4 out of 8(50%) patients in PP have used steroids during the clinical investigation. The mean steroid dosage for these patients in the ITT set decreased from a mean 12.4 mg to 10 mg daily on average from Baseline to week 12.CONCLUSION: Adacolumn; GMA apheresis treatment was effective in pediatric patients with moderate active Ulcerative Colitis. No new safety signals were reported. The present data contribute to considering GMA apheresis as a therapeutic option in pediatric patients having failed first line therapy. | Tarja Ruuska Peter Küster Lena Grahnquist Fredrik Lindgren Anne Vibeke Wewer | 2016 | World Journal of Gastroenterology2016,22,17: | 3 |
| 3 | Biomass accumulations and nutrient uptake of plants cultivated on artificial floating beds in China’s rural area显示文摘 | Liandong Zhu Zhaohua Li Tarja Ketola | 2011 | Ecological Engineering2011,,10: | 2 |
| 4 | Overlap Syndrome of Asthma and COPD Predicts Low Quality of Life显示文摘 | Paula Kauppi Henna Kupiainen Ari Lindqvist Lauri Tammilehto Maritta Kilpel? inen Vuokko L. Kinnula Tari Haahtela Tarja Laitinen | 2011 | Journal of Asthma2011,,3: | 2 |
| 5 | Hormones and Breathing显示文摘 | Tarja Saaresranta Polo Olli | 2002 | Chest2002,122,6: | 1 |
| 6 | Measuring quality of life of Finnish children with cerebral palsy 显示文摘 | Brling S Tarja V Helena M | 2013 | J Pediatr Rehabil Med2013,6,3: | 1 |
| 7 | Molecular and structural composition of phospholipid membranes in livers of marine and freshwater fish in relation to temperature显示文摘 | Indranil Dey Csaba Buda Tarja Wiik | 1993 | Biochemistry1993,90,: | 1 |
| 8 | Respiratory insufficienty in postmenopaused women :sustained improvement of gas exchange with short -term Medroxyprogesterone Acetate显示文摘 | Tarja Saaresranta Paori Plol - kantola Kertim Iriala | 1999 | Chest1999,115,6: | 1 |
| 9 | Leucocyte apheresis in the treatment of paediatric ulcerative colitis显示文摘 | Tarja Ruuska Marja-Leena L? hdeaho Yelda Sutas Merja Ashorn Juhani Gr? nlund | 2007 | Scandinavian Journal of Gastroenterology2007,,11: | 1 |
| 10 | Invasive Group A Streptococcal Infections in Children: A Nationwide Survey in Finland显示文摘 | Terhi Tapiainen Saana Launonen Marjo Renko Harri Saxen Eeva Salo Matti Korppi Leena Kainulainen Tarja Heiskanen-Kosma Laura Lindholm Jaana Vuopio Tiina Huotari Jarmo Rusanen Matti Uhari | 2016 | The Pediatric Infectious Disease Journal2016,,: | 1 |
| 11 | The synaptosomal membrane bound ATPase as target for the neurotoxic effects pyrethriods, permethrin and cypermethrin显示文摘 | Irma kakko Tarja Toimela Hanna Tahti | 2003 | Chemosphere2003,51,: | 1 |
| 12 | A value efficiency approach to incorporating preference information in data envelopment analysis 显示文摘 | Merja Halme Tarja Joro etal | 1999 | Management Science1999,45,: | 1 |
| 13 | Comparison of stroke features and disability in daily life patients with ischemic stroke aged 55 to 70 and 71 to 85 years 显示文摘 | Tarja P Timo E Risto V | 1997 | Stroke1997,28,4: | 1 |
| 14 | Chlorophyllasel, a damage control enzyme,affects the balance between defense pathways in plants 显示文摘 | Tarja K Günter B Jing L | 2005 | The Plant Cell2005,17,: | 1 |
| 15 | Fine particle concentrations in buses and taxis in Florence,Italy显示文摘 | Fondelli M C Elisabetta Chellini Tarja Yli-Tuomi | 2008 | Atmospheric Environment2008,42,35: | 1 |
| 16 | Serum and follicular fluid leptin during in vitro fertilizsation: Relationship among leptin increase,body fat mass,and reduced ovarian response 显示文摘 | Jarna MM Mikko L | 1999 | J Clin Endocrinol Metab1999,84,: | 1 |
| 17 | Nurse'self-reflection via videotaping to improve communication skills in health counselling显示文摘 | Leena P Tarja K | 1999 | Patient Education and counselling1999,36,1: | 1 |
| 18 | A value efficiency approach to incorporating preference information in data envelopment analysis显示文摘 | Merja Halme Tarja Joro Pekka Korhonen Seppo Salo Jyrki Wallenius | 1999 | Management Science1999,45,: | 1 |
| 19 | Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy显示文摘 | Tarja Vihtam?ki Jouko Parantainen Anna-Maija Koivisto Timo Mets?-Ketel? Risto Tuimala | 2002 | Maturitas2002,,2: | 1 |
| 20 | Peat Biofilters in Long-Term Experiments for Removing Odorous Sulphur Compounds显示文摘 | Tarja Hartikainen Pertti J. Martikainen Minna Olkkonen Juhani Ruuskanen | 2002 | Water Air and Soil Pollution (-)2002,,1: | 1 |