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| 1 | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a frequently reported condition in patients with inflammatory bowel disease(IBD).Both intestinal inflammation and metabolic factors are believed to contribute to the pathogenesis of IBDassociated NAFLD.AIM To evaluate the prevalence of steatosis and liver fibrosis(LF)in a cohort of IBD patients and the identification of metabolic-and IBD-related risk factors for NAFLD and LF.METHODS IBD patients were consecutively enrolled from December 2016 to January 2018.Demographic,anthropometric and biochemical data were collected so as eating habits.Abdominal ultrasound and transient elastography were performed to evaluate the presence of NAFLD and LF respectively.RESULTS A total of 178 consecutive patients were enrolled and included in the analysis(95 Ulcerative colitis,83 Crohn’s disease).NAFLD was detected by imaging in 72(40.4%)patients.Comparison between patients with and without NAFLD showed no significant differences in terms of IBD severity,disease duration,location/extension,use of IBD-related medications(i.e.,steroids,anti-TNFs,and immunomodulators)and surgery.NAFLD was significantly associated with the presence of metabolic syndrome[MetS;odds ratio(OR):4.13,P=0.001]and obesity defined by body mass index(OR:9.21,P=0.0002).IBD patients with NAFLD showed higher caloric intake and lipid consumption than those without NAFLD,regardless disease activity.At the multivariate analysis,male sex,advanced age and high lipid consumption were independent risk factors for the development of NAFLD.An increased liver stiffness was detected in 21 patients(16%)and the presence of MetS was the only relevant factor associated to LF(OR:3.40,P=0.01).CONCLUSION In this study,we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. | Salvatore Magrì Danilo Paduano Fabio Chicco Arianna Cingolani Cristiana Farris Giovanna Delogu Francesca Tumbarello Mariantonia Lai Alessandro Melis Laura Casula Massimo C Fantini Paolo Usai | 2019 | World Journal of Gastroenterology2019，25，37： | 8 |
| 2 | Distributed multi-generation: A comprehensive view显示文摘 | Gianfranco Chicco Pierluigi Mancarella | 2007 | Renewable and Sustainable Energy Reviews2007，，3： | 3 |
| 3 | Customer characterization options for improving the tariff offer显示文摘 | Chicco G Napoli R Postolache P | 2003 | IEEE Trans on Power Systems2003，18，1： | 1 |
| 4 | Overview and performance assessment of the clustering methods for electrical load pattern grouping显示文摘 | Chicco G | 2012 | Energy2012，42，1： | 1 |
| 5 | Assessment of the greenhouse gas emissions from cogeneration and trigeneration systems. Part II: Analysis techniques and application cases显示文摘 | Pierluigi Mancarella Gianfranco Chicco | 2007 | Energy2007，，3： | 1 |
| 6 | Elec- tricity customer classification using frequency:Do- main load pattern data 显示文摘 | Carpaneto E Chicco G Napoli R Scutariu M | 2006 | International Journal of Electrical Power & Energy Systems2006，28，1： | 1 |
| 7 | Docosahexaenoic acid supplementation does not improve Western dietinduced cardiomyopathy in rats 显示文摘 | 1eckel KM Veeramachaneni DNR Chicco AJ | 2012 | PloS one2012，7，51： | 1 |
| 8 | Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoformof the KATP channel in the rat 显示文摘 | Brown DA Chicco AJ Jew KN | 2005 | J Physiol2005，569，3： | 1 |
| 9 | The Fe-rich corner of the metastable Fe-Cr-C liquidus surface显示文摘 | Warren R Thorpe Bruno Chicco | 1985 | Metallurgical Transactions A1985，16，9： | 1 |
| 10 | Comparison among clustering techniques for electricity customer classification显示文摘 | Chicco G Napoli R Piglione F | 2006 | IEEE Transactions on Power Systems2006，21，2： | 1 |
| 11 | Branch current decomposition method for loss allocation in radial distribution systems with distributed geaeration显示文摘 | Carpaneto E Chicco G Akilimali J S | 2006 | IEEE Transactions on Power Systems2006，21，3： | 1 |
| 12 | Sex-specific and exercise-acquired cardioprotection is abolished by sarcolemmal KATP channel blockade in the rat heart显示文摘 | Chicco AJ Johnson MS Armstrong CJ | 2007 | Am J Physiol Heart Circ Physiol2007，292，5： | 1 |
| 13 | Worst-load-increase direction method for fast identification of voltage-weakness indicators显示文摘 | Bompard E Carpaneto E Chicco G | 1998 | IEEE Proceedings-Generation Transmission and Distribution1998，145，1： | 1 |
| 14 | Effect of dietary fish oil on insulin sensitivity and metabolic fate of glucose in the skeletal muscle of normal rats显示文摘 | D'Alessandro ME Lombardo YB Chicco A | 2002 | Ann Nutr Metab2002，46，： | 1 |
| 15 | Branch current decomposition method for loss allocation in radial distribution systems with distributed generation 显示文摘 | Carpaneto E Chicco G | 2006 | IEEE Trans on Power Systems2006，21，3： | 1 |
| 16 | From cogeneration to trigeneration: profitable alternativesin a competitive market显示文摘 | Chicco G Mancarell P | 2006 | IEEE Transactions on Energy2006，21，： | 1 |
| 17 | In vitro phytase activity of rumen microorganism and in situ degradation of fi- brous substrate in sheep fed different feeding regimes 显示文摘 | GODOY S CHICCO C F | 2005 | Zootecnia Trop2005，23，1： | 1 |
| 18 | Worst-load-increase direction method for fast identification of voltage - weakness indicators 显示文摘 | BORNPARD E CARPANETO E CHICCO G | 1998 | IEEE Proceedings - Generation Trans - mission and Distribution1998，145，1： | 1 |
| 19 | Experimental study of vanadium carbide and carbonit ride coatings 显示文摘 | Chicco B Borbidge W E Summerville E | 1999 | Materials Science and Engineering1999，30，： | 1 |
| 20 | Allocation of the reactive power support requirement in multitransaction networks显示文摘 | Chicco G Gross G Tao Shu | 2002 | IEEE Trans on Power Systems2002，17，4： | 1 |
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