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| 1 | O(~3P)+O_2H——OH+O_2反应机理的密度泛函理论研究显示文摘用密度泛函理论方法研究了 O( 3P)与 O2 H反应生成羟基和氧分子的反应机理 .在 PW91 /6-31 +G*水平上用梯度解析技术全自由度优化上述反应物、产物和反应路径上的中间体及过渡态几何构型 ,并通过频率振动分析加以确认 ,计算 IRC反应路径及中间体异构化过程 ,确定了此反应的可能反应通道 .结果表明 :该反应是多通道多步骤的强放热反应 .首先形成顺式或反式 O3H富能中间体 ,此过程无能垒 ;然后跨过一个能垒分解成产物 OH和 O2 .通道 IM1→ TS1比 IM2→ TS2克服的能垒要大 ,反应放热 372 .82 2 k J.mol- 1 .IM1 TS3 | 潘秀梅 王荣顺 苏忠民 James Tyrrell | 2001 | 高等学校化学学报2001，22，12： | 13 |
| 2 | Transjugular intrahepatic porto 全身的分流在老: 为门高血压的复杂并发症的减轻显示文摘 AIM:To present a dedicated series of transjugular intrahepatic porto-systemic shunts(TIPS) in the elderly since data is sparse on this population group.METHODS:A retrospective review was performed of patients at least 65 years of age who underwent TIPS at our institutions between 1997 and 2010.Twentyfive patients were referred for TIPS.We deemed that 2 patients were not considered appropriate candidates due to their markedly advanced liver disease.Of the 23 patients suitable for TIPS,the indications for TIPS placement was portal hypertension complicated by refractory ascites alone(n = 9),hepatic hydrothorax alone(n = 2),refractory ascites and hydrothorax(n = 1),gastrointestinal bleeding alone(n = 8),gastrointestinal bleeding and ascites(n = 3).RESULTS:Of these 23 attempted TIPS procedure patients,21 patients had technically successful TIPS procedures.A total of 29 out of 32 TIPS procedures including revisions were successful in 21 patients with a mean age of 72.1 years(range 65-82 years).Three of the procedures were unsuccessful attempts at TIPS and 8 procedures were successful revisions of our existing TIPS.Sixteen of 21 patients who underwent successful TIPS(excluding 5 patients lost to follow-up) were followed for a mean of 14.7 mo.Ascites and/or hydrothorax was controlled following technically successful procedures in 12 of 13 patients.Bleeding was controlled following technically successful procedures in 10 out of 11 patients.CONCLUSION:We have demonstrated that TIPS is an effective procedure to control refractory complications of portal hypertension in elderly patients. | Mubin I Syed Hetal Karsan Hector Ferral Azim Shaikh Uzma Waheed Talal Akhter Alan Gabbard Kamal Morar Robert Tyrrell | 2012 | World Journal of Hepatology2012，4，2： | 4 |
| 3 | Accuracy and Clinical Usefulness of Intracerebral Hemorrhage Grading Scores: A Direct Comparison in a UK Population显示文摘 | Adrian R. Parry-Jones Kamran A. Abid Mario Di Napoli Craig J. Smith Andy Vail Hiren C. Patel Andrew T. King Pippa J. Tyrrell | 2013 | Stroke2013，，7： | 2 |
| 4 | 年龄相关性线粒体功能障碍加速动脉粥样硬化形成显示文摘老化是动脉粥样硬化的最强危险因素之一。然而,老化是否独立于慢性高血脂症而增加动脉粥样硬化的风险尚不清楚。该研究旨在确定高血脂症诱导前的血管老化是否会加速动脉粥样硬化的形成。研究者分析了幼年和老年正常血脂野生型(wild type,WT)、无疾病小鼠的主动脉,发现老化导致白细胞介素(interleukin,IL)6水平升高和线粒体功能障碍,并与线粒体自噬增加和其相关蛋白Parkin增加相关。在主动脉组织培养中,研究者发现随着老化的出现,线粒体功能障碍与IL-6存在正反馈关系。研究者通过诱导低密度脂蛋白受体的肝脏特异性降解,再结合10周的西方食物喂养,在老年和幼年小鼠中诱发急性高血脂症,发现老年WT小鼠的动脉粥样硬化增强。高血脂症进一步降低了老年小鼠的线粒体功能,增加了主动脉中Parkin的水平,但幼鼠则没有。 | 刘青(译) 叶鹏(摘、审校) Tyrrell DJ Blin M Song J Wood S Zhang M Beard DA Goldstein D | 2020 | 中华高血压杂志2020，28，2： | 2 |
| 5 | Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite 显示文摘 | Keyse SM Tyrrell RM | 1989 | Proc Natl Acad Sci USA1989，86，： | 1 |
| 6 | A framework for assessing direct economic impacts of tourist events: distinguishing ori- gins,destinations, and causes of expenditures显示文摘 | TYRRELL T J JOHNSTON R J | 2001 | J Travel Res2001，40，： | 1 |
| 7 | Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm 显示文摘 | Longley B J Tyrrell L Lu SZ | 1996 | Nat Genet1996，12，3： | 1 |
| 8 | Singlet molecular oxygen (O2):Apossible effector of eukaryotic gene expression显示文摘 | RYTER S W TYRRELL R M | 1998 | Free Radical Biology and Medicine1998，24，： | 1 |
| 9 | Change in viability of maize during high-temperature drying显示文摘 | Lescano C L Tyrrell D E | | 0，，： | 1 |
| 10 | Selective venous sampling for ACTH in Cushing's syndrome: differentiation between Cushing disease and the ectopic ACTH syndrome显示文摘 | Findling JW Aron DC Tyrrel! JB | 1981 | Ann Intern Med1981，94，64： | 1 |
| 11 | Autoantibodies in pediatric systemic lupus erythematosus: ethnic grouping, cluster analysis, and clinical correlations显示文摘 | Jurencak R Fritzler M Tyrrell P | 2009 | J Rheumatol2009，36，2： | 1 |
| 12 | A methodology for estimating the at- tendance and economic impact of an open-gate festival显示文摘 | TYRRELL B ISMAIL J | 2005 | E- vent Manage2005，9，： | 1 |
| 13 | The relative influences of nitrogen and phosphorus on oceanic primary production显示文摘 | TYRRELL T | 1999 | Nature1999，400，： | 1 |
| 14 | Embryonics + Immunotronics: A Bio - Inspired Approach to Fault Tolerance显示文摘 | Daryl Bradley Andy Tyrrell | 2000 | IEEE2000，，： | 1 |
| 15 | Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites显示文摘 | Tyrrell JS Morton C Campbell SM | 2011 | Br J Demlatol2011，164，6： | 1 |
| 16 | Coexpression of RTI40 with alveolar epithelial type I1 cell proteins in lungs following injury: identification of alveolar intermediate cell types 显示文摘 | CLEGG G R TYRRELL C McKECHNIE S R | 2005 | Am J Physiol Lung Cell Mol Physio12005，289，3： | 1 |
| 17 | Novel bio-inspired approach for fault-tolerant VLSI systems 显示文摘 | Samie M Dragffy G Tyrrell A M | 2012 | IEEE Transactions on Very Large Scale Integration (VLSI) Systems2012，21，10： | 1 |
| 18 | Cytokines in parvovirus B19 infec-tion as an aid to understanding chronic fatigue syndrome显示文摘 | Kerr JR Tyrrell DA | 2003 | Curr Pain Headache Rep2003，7，5： | 1 |
| 19 | Induction of Oxidative DNA Base Damage in Human Skin Cells by UV and Near Visible Radiation显示文摘 | KVAM E TYRRELL R | 1997 | Carcinogenesis1997，18，12： | 1 |
| 20 | The subtle effects of sea water acidification on the amphipod Gammarus locusta显示文摘 | Hauton C Tyrrell T Williams J E | 2009 | Biogeosciences2009，，6： | 1 |
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