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| 1 | Postoperative deep shoulder infections following rotator cuff repair显示文摘Rotator cuff repair(RCR) is one of the most commonly performed surgical procedures in orthopaedic surgery. The reported incidence of deep soft-tissue infections after RCR ranges between 0.3% and 1.9%. Deep shoulder infection after RCR appears uncommon, but the actual incidence may be higher as many cases may go unreported. Clinical presentation may include increasing shoulder pain and stiffness, high temperature, local erythema, swelling, warmth, and fibrinous exudate. Generalized fatigue and signs of sepsis may be present in severe cases. Varying clinical presentation coupled with a low index of suspicion may result in delayed diagnosis. Laboratory findings include high erythrocyte sedimentation rate and C-reactive protein level, and, rarely, abnormal peripheral blood leucocyte count. Aspiration of glenohumeral joint synovial fluid with analysis of cell count, gram staining and culture should be performed in all patients suspected with deep shoulder infection after RCR. The most commonly isolated pathogens are Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. Management of a deep soft-tissue infection of the shoulder after RCR involves surgical debridement with lavage and long-term intravenous antibiotic treatment based on the pathogen identified. Although deep shoulder infection after RCR is usually successfully treated, complications of this condition can be devastating. Prolonged course of intravenous antibiotic treatment, extensive soft-tissue destruction and adhesions may result in substantially diminished functional outcomes. | Kivanc Atesok Peter MacDonald Jeff Leiter Sheila McRae Greg Stranges Jason Old | 2017 | World Journal of Orthopedics2017，8，8： | 3 |
| 2 | Worsening renal function in heart failure: The need for a consensus definition显示文摘 | Noella J. Sheerin Phillip J. Newton Peter S. Macdonald Dominic Y.C. Leung David Sibbritt Stephen Timothy Spicer Kay Johnson Henry Krum Patricia M. Davidson | 2014 | International Journal of Cardiology2014，，： | 2 |
| 3 | Acromioclavicular and Sternoclavicular Joint Injuries显示文摘 | Peter B. MacDonald Pierre Lapointe | 2008 | Orthopedic Clinics of North America2008，，4： | 2 |
| 4 | 在 7T 的多原子的磁性的回声光谱学的应用显示文摘 AIM: To discuss the advantages of ultra-high field (7T) for 1H and 13C magnetic resonance spectroscopy (MRS) studies of metabolism.made at both 3 and 7T using 1H MRS. Measurements of glycogen and lipids in muscle were measured using 13C and 1H MRS respectively. RESULTS: In the brain, increased signal-to-noise ratio (SNR) and dispersion allows spectral separation of the amino-acids glutamate, glutamine and γ-aminobutyric acid (GABA), without the need for sophisticated editing sequences. Improved quantification of these me-tabolites is demonstrated at 7T relative to 3T. SNR was 36% higher, and measurement repeatability (% coefficients of variation) was 4%, 10% and 10% at 7T, vs 8%, 29% and 21% at 3T for glutamate, glutamine and GABA respectively. Measurements at 7T were used to compare metabolite levels in the anterior cingulate cortex (ACC) and insula. Creatine and glutamate levels were found to be significantly higher in the insula compared to the ACC (P < 0.05). In muscle, the increased SNR and spectral resolution at 7T enables interleaved studies of glycogen (13C) and intra-myocellular lipid (IMCL) and extra-myocellular lipid (EMCL) (1H) following exercise and refeeding. Glycogen levels were sig-nificantly decreased following exercise (-28% at 50% VO2 max; -58% at 75% VO2 max). Interestingly, levels of glycogen in the hamstrings followed those in the quadriceps, despite reduce exercise loading. No changes in IMCL and EMCL were found in the study. CONCLUSION: The demonstrated improvements in brain and muscle MRS measurements at 7T will increase the potential for use in investigating human metabolism and changes due to pathologies. | Mary C Stephenson Frances Gunner Antonio Napolitano Paul L Greenhaff Ian A MacDonald Nadeem Saeed William Vennart Susan T Francis Peter G Morris | 2011 | World Journal of Radiology2011，3，4： | 2 |
| 5 | Long-term quality of life in trauma patients following the full spectrum of tibial injury (fasciotomy, closed fracture, grade IIIB/IIIC open fracture and amputation)显示文摘 | Peter V. Giannoudis Paul J. Harwood George Kontakis Mohamad Allami David Macdonald Simon P. Kay Paul Kind | 2008 | Injury2008，，2： | 1 |
| 6 | Erythromycin-in- duced cardiac toxicity显示文摘 | Orban Z MacDonald LL Peters MA | 1995 | Am J Cardiol1995，75，： | 1 |
| 7 | Erythromycin-in- duced cardiac toxicity显示文摘 | Orban Z MacDonald LL Peters MA | 1995 | Am J Cardiol1995，75，12： | 1 |
| 8 | Gemcitabine and Cisplatin for Patients with Metastatic or Recurrent Esophageal Carcinoma: A Southwest Oncology Group Study显示文摘 | Susan G. Urba Kari Chansky Peter J. vanVeldhuizen Robert E. Pluenneke Jacqueline K. Benedetti John S. Macdonald James L. Abbruzzese | 2004 | Investigational New Drugs2004，，1： | 1 |
| 9 | The Role of Subacromial Decompression in Patients Undergoing Arthroscopic Repair of Full-Thickness Tears of the Rotator Cuff: A Systematic Review and Meta-analysis显示文摘 | Jaskarndip Chahal Nathan Mall Peter B. MacDonald Geoffrey Van Thiel Brian J. Cole Anthony A. Romeo Nikhil N. Verma | 2012 | Arthroscopy: The Journal of Arthroscopic and Related Surgery2012，，5： | 1 |
| 10 | Multiple Mechanisms of Ketamine Blockade of N-methyl-D-aspartate Receptors显示文摘 | Beverley A. Orser Peter S. Pennefather John F. MacDonald | 1997 | Anesthesiology1997，，4： | 1 |
| 11 | Acromioclavicular and SternoclavicularJoint Injuries显示文摘 | Peter B MacDonald MD | 2008 | J Orthopedic Clinics of North America2008，39，4： | 1 |
| 12 | Preventing Vasospasm Improves Outcome After Aneurysmal Subarachnoid Hemorrhage: Rationale and Design of CONSCIOUS-2 and CONSCIOUS-3 Trials显示文摘 | R. Loch Macdonald Randall T. Higashida Emanuela Keller Stephan A. Mayer Andy Molyneux Andreas Raabe Peter Vajkoczy Isabel Wanke Aline Frey Angelina Marr Sébastien Roux Neal F. Kassell | 2010 | Neurocritical Care2010，，3： | 1 |
| 13 | Investigation of the haemodynamic effects of exenatide in healthy male subjects显示文摘 | Buddhike Mendis Elizabeth Simpson Ian MacDonald Peter Mansell | 2012 | British Journal of Clinical Pharmacology2012，，3： | 1 |
| 14 | Tolerability and efficacy of carvedilol in patients with New York Heart Association class IV heart failure显示文摘 | Peter S Macdonald Anne M Keogh Christina L Aboyoun Mayanna Lund Raul Amor Dermot J McCaffrey | 1999 | Journal of the American College of Cardiology1999，，： | 1 |
| 15 | What makes a successful volunteer Expert Patients Programme tutor? Factors predicting satisfaction, productivity and intention to continue tutoring of a new public health workforce in the United Kingdom显示文摘 | Wendy Macdonald Evangelos Kontopantelis Peter Bower Anne Kennedy Anne Rogers David Reeves | 2008 | Patient Education and Counseling2008，，1： | 1 |
| 16 | Modeling the free surface of an unconfined aquifer near a recirculation well显示文摘 | Thomas R Macdonald Peter K K | 1993 | Groundwater1993，，31： | 1 |
| 17 | Bystander-mediated genomic instability after high LET radiation in murine primary haemopoietic stem cells显示文摘 | Deborah A. Bowler Stephen R. Moore Denise A. Macdonald Sharon H. Smyth Peter Clapham Munira A. Kadhim | 2005 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2005，，1： | 1 |
| 18 | Suppression of mouse hepatocyte apoptosis by peroxisome proliferators: role of PPARalpha and TNFalpha显示文摘 | Hasmall SC James NH Macdonald N Gonzalez FJ Peters JM Roberts RA | 2000 | Mutat Res2000，448，2： | 1 |
| 19 | Green leaf volatiles inhibit response of red pine cone beetle Conphthorus resinosae (Coleoptera:Scolytidae) to a sex pheromone显示文摘 | PETER D G MACDONALD L M | 1999 | Naturwis-senschaften1999，86，： | 1 |
| 20 | Safety and Efficacy of Transition From Subcutaneous Treprostinil to Oral Sildenafil in Patients With Pulmonary Arterial Hypertension显示文摘 | Anne M. Keogh Andrew Jabbour Robert Weintraub Karen Brown Chris S. Hayward Peter S. Macdonald | 2007 | Journal of Heart and Lung Transplantation2007，，11： | 1 |
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