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| 1 | Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients显示文摘AIM To investigate the role of genetic variants of angiotensin converting enzyme(ACE) and angiotensinogen(AGT) genes in the antiproteinuric efficacy of ACE inhibitor therapy in diabetic nephropathy(DN) patients.METHODS In the present study, 270 type 2 diabetes mellitus patients with nephropathy were enrolled and treated with ACE inhibitor(ramipril) and followed at 6 mo for renal function and albumin excretion by estimating serum creatinine, end stage renal disease, and albumin/creatinine ratio(ACR) in urine. Genotyping of ACE I/D and AGT M235 T polymorphisms were performed by using primer specific polymerase chain reaction(PCR) and PCR-RFLP techniques, respectively. RESULTS Forty-eight percent of DN patients(responders) benefited with respect to proteinuria from ACE inhibitor therapy at 6 mo follow-up. A significant reduction in ACR was observed after 6 mo treatment with ACE inhibitor irrespective of whether DN patients were micro-albuminuric(≥ 30 and < 300 mg/g creatinine) or macro-albuminuric(≥ 300 mg/g creatinine) at the time of enrollment. However, macro-albuminuric patients(55%) showed better response to therapy. A reduction in urinary ACR was found independent of genotypes of ACE I/D and AGT M235 T polymorphisms although macro-albuminuric patients having TT genotype showed statistically insignificant increased response(72%). CONCLUSION ACE inhibitor therapy reduced urinary ACR by ≥ 30% in 50% of DN patients and the response is independent of ACE I/D and AGT M235 T polymorphisms. | Neerja Aggarwal Pawan Kumar Kare Parul Varshney Om Prakash Kalra Sri Venkata Madhu Basu Dev Banerjee Anil Yadav Alpana Raizada Ashok Kumar Tripathi | 2017 | World Journal of Diabetes2017,8,3: | 4 |
| 2 | Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication显示文摘 | Nai-Yun Hsu Olha Ilnytska Georgiy Belov Marianita Santiana Ying-Han Chen Peter M. Takvorian Cyrilla Pau Hilde van der Schaar Neerja Kaushik-Basu Tamas Balla Craig E. Cameron Ellie Ehrenfeld Frank J.M. van Kuppeveld Nihal Altan-Bonnet | 2010 | Cell2010,,5: | 1 |
| 3 | Acute open brain herniation during elective tumour resection显示文摘 | Hemanshu P Mary A Neerja J | 2007 | Internet J Anesthesiology2007,11,2: | 1 |
| 4 | Fabrication and characterization of thin films of single-walled carbon nan- otube bundles on flexible plastic substrates显示文摘 | Neerja Saran Kunjal Parikh Dong-Seok Suh | 2004 | American Chemical Society2004,126,14: | 1 |
| 5 | A meta-analysis of human papillomavirus type-distribution in women from South Asia: Implications for vaccination 显示文摘 | Neerja B Neena L YAN Ping-bao | 2008 | Vaccine2008,261,: | 1 |
| 6 | Acute open brain herniation during elective tumour resection显示文摘 | Hemanshu P Mary A Neerja J | 2007 | Internet J Anesthesiology2007,11,2: | 1 |
| 7 | Neoadjuvant chemotherapy for epithelial ovarian cancer—role of apoptosis显示文摘 | Tania Dutta Himani Sharma Lalit Kumar A. K. Dinda Sunesh Kumar Neerja Bhatla Neeta Singh | 2005 | Cancer Chemotherapy and Pharmacology2005,,4: | 1 |
| 8 | Natural Products:A safest Approach for Obesity显示文摘肥胖作为一个社会问题被认出,与严重健康风险联系了并且增加了死亡。众多的试用被进行了发现并且通过草药的来源开发新反肥胖药最小化与现在的反肥胖药联系的不利反应。药在全世界在药的各种各样的传统的系统被记录几百年了的自然产品的使用。这评论集中于象 Achyranthus aspera 那样的药用的植物,山茶 sinensis, Emblica officinalis, Garcinia cambogia, Terminalia arjuna,等等,在 Ayurvedic, Unani, Siddha 和汉语传统地被使用,等等,药的系统。评论也加亮象 escins, perennisosides, dioscin, gracillin,等等,和象 Nelumbo nucifera 一样的植物的各种各样的摘录那样的最近的报导 phytochemicals,人参属装饰用的梨树, Cichorium intybus, Cyperus rotundus, Paeonia suffruticosa,等等,它成功地为肥胖的处理被识别了。 | Neeru Vasudeva Neerja Yadav Surendra Kumar Sharma | 2012 | Chinese Journal of Integrative Medicine2012,18,6: | 1 |
| 9 | Iridoid glycosides from Gmelina arborea显示文摘 | Neerja Tiwari Akhilesh K. Yadav Pooja Srivastava Karuna Shanker Ram K. Verma Madan M. Gupta | 2008 | Phytochemistry2008,,12: | 1 |
| 10 | Foliar Application of Benzothiadiazole and Salicylic Acid to Combat Sheath Blight Disease of Rice显示文摘A field study was undertaken to ascertain the effects of elicitors viz.benzothiadiazole(BTH)and salicylic acid(SA)on defense related enzymes viz.peroxidase,phenylalanine ammonia lyase,superoxide dismutase,chitinase andβ-1,3-glucanase,and phenols in rice(Pusa Basmati I)plants.First foliar spray of BTH(50 mg/kg)and SA(50 mg/kg)was done at the maximum tillering stage and inoculation with Rhizoctonia solani was carried 24 h after elicitor treatment.Elicitors were further sprayed at every growth stage.Time course analysis showed peak accumulation of defense related enzymes and phenols in the rice leaves treated with BTH and SA,and accumulation was the highest at the flowering stage.Higher enzymatic activity was observed in elicitor treated plants inoculated with R.solani.Compared to the untreated control plants,application of elicitors before R.solani inoculation significantly elicited the defense related enzymes and phenols.Moreover,application of elicitors had a positive effect on yield and disease reduction.It is suggested that pretreatment of rice leaves with BTH and SA could be used to enhance the level of protection against sheath blight and to improve rice yield in the fields. | Neerja SOOD B.S.SOHAL J.S.LORE | 2013 | Rice science2013,20,5: | 1 |
| 11 | Neoadjuvant chemotherapy with weekly paclitaxel and carboplatin followed by chemoradiation in locally advanced cervical carcinoma: A pilot study显示文摘 | Rajkumar Bikramjit Singh Subhash Chander B.K. Mohanti Sushmita Pathy Sunesh Kumar Neerja Bhatla Sanjay Thulkar Sreenivas Vishnubhatla Lalit Kumar | 2013 | Gynecologic Oncology2013,,: | 1 |
| 12 | A meta-analysis of human papillomavirus type-distribution in women from South Asia:Implications for vaccination显示文摘 | Neerja B Neena L YAN Ping-bao | 2008 | Vaccine2008,26,23: | 1 |
| 13 | Peptide Inhibition of HIV-1显示文摘 | Neerja Kaushik-Basu Amartya Basu Dylan Harris | | BioDrugs0,,: | 1 |
| 14 | ABC multidrug transporter Cdr1 p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry 显示文摘 | Sudhakar J Neelam D Neerja K | 2004 | FEMS Yeast Research2004,5,: | 1 |
| 15 | Epiduml butorphanol-bupiva- caine analgesia for postoperative pain relief after abdominal hysterec- tomy显示文摘 | Neerja Bharti MD Pramila Chari MD | 2009 | Journal of Clinical Anesthesia2009,21,: | 1 |
| 16 | Purification and characterization of pectinase from Apple pomace and evaluation of its efficacy in fruit juice extraction and clarification显示文摘 | V K Joshi Mukesh Parmar Neerja Rana | 2011 | Indian Journal of Natural Products and Resources2011,2,2: | 1 |
| 17 | Distribution of fitness effects caused by random insertion mutations in Escherichia coli显示文摘 | Santiago F. Elena Lynette Ekunwe Neerja Hajela Shenandoah A. Oden Richard E. Lenski | 1998 | Genetica1998,,0: | 1 |
| 18 | CSF p-Tau levels in the prediction of Alzheimer’s disease显示文摘 | Ramesh J. L. Kandimalla Sudesh Prabhakar Willayat Yousuf Wani Alka Kaushal Nidhi Gupta Deep Raj Sharma V. K. Grover Neerja Bhardwaj Kajal Jain Kiran Dip Gill | 2013 | Biology Open2013,,11: | 1 |
| 19 | CRL4 Cdt2 Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation显示文摘 | Tarek Abbas Etsuko Shibata Jonghoon Park Sudhakar Jha Neerja Karnani Anindya Dutta | 2010 | Molecular Cell2010,,1: | 1 |
| 20 | Epidural butorphanol-bupivacaine analgesia for postoperative pain relief after abdominal hysterectomy 显示文摘 | Neerja B Pramila C | 2009 | J Clin Anesth2009,21,1: | 1 |