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| 1 | Nano-formulations for transdermal drug delivery:A review显示文摘Transdermal drug delivery refers to a means of delivering drugs through the surface of the skin for local or systemic treatment. The drug functions after absorption through the skin into the systemic circulation via capillary action at a certain rate. Use of traditional physical and chemical enhancers to improve the transdermal permeation rate by increasing drug solubility, diffusion coefficient, and reservoir effect is not feasible owing to the toxic side effects of the overuse of chemical penetration enhancers. Nanoformulations generally vary in size and range from 10 nm to 100 nm. The smaller particle size leads to increased drug permeability, stability, retention, and targeting, making nano-formulations suitable for transdermal drug delivery. The different applications of nano-formulations(vesicles or nanoparticles and nanoemulsions) have been widely studied. Here, the classification, characteristics, transdermal mechanism, and application of the most popular nano-formulations in transdermal drug delivery system are reviewed. | Xingli Zhou Ying Hao Liping Yuan Sushmita Pradhan Krista Shrestha Ojaswi Pradhan Hongjie Liu Wei Li | 2018 | Chinese Chemical Letters2018，29，12： | 17 |
| 2 | 痤疮相关微生物菌群间相互作用机制研究进展显示文摘痤疮是毛囊皮脂腺的一种慢性炎症性疾病,痤疮皮损内主要菌群包括丙酸杆菌、葡萄球菌、马拉色菌等,各菌通过分泌、诱导合成各种细胞因子、蛋白酶、脂肪酸,彼此形成复杂的分子信号网络,最终调控宿主皮肤细胞内外的炎症反应。本文就痤疮皮损中主要的细菌与真菌间的相互作用及可能机制进行阐述。 | 徐小茜 Sushmita Pradhan 冉玉平 | 2021 | 中国皮肤性病学杂志2021，35，2： | 6 |
| 3 | 伊曲康唑口服液治疗婴儿脓癣五例并文献复习显示文摘本文报道5例经由伊曲康唑口服液治疗成功的婴儿脓癣并复习相关文献。5例患儿,年龄2~12个月,临床表现为头皮红斑、鳞屑、脓肿、脱发,诊断依据为皮肤镜下病发特点及取病发行钙荧光白染色后荧光显微镜检确认真菌孢子和(或)菌丝累及毛干、头皮。5例经伊曲康唑口服液5 mg/kg·d治疗后均痊愈,疗程3~12周。1例治疗过程中出现可逆性轻度短暂腹泻,未停药逐渐缓解。通过文献检索到7例伊曲康唑治疗婴儿头癣的报道,对病例特点及疗效进行分析总结。伊曲康唑口服液治疗婴儿头癣方便、安全、有效且耐受性良好。 | 张牧秋 庄凯文 冉昕 周宜可 Sushmita Pradhan 冉玉平 | 2023 | 中国麻风皮肤病杂志2023，39，4： | 2 |
| 4 | 伊曲康唑胶囊微丸在蒸馏水、牛奶、可乐中溶出度分析显示文摘目的临床上发现用可乐或牛奶送服伊曲康唑胶囊可提高其生物利用度和治疗效果,本研究旨在比较伊曲康唑胶囊微丸在蒸馏水、牛奶(全脂、低脂以及脱脂牛奶,伊利乳业)和可乐(可口可乐)中的溶出度。方法进行伊曲康唑微丸溶出度试验,采用液相色谱-串联质谱法对伊曲康唑微丸在溶出度试验中不同阶段的溶出浓度进行检测。结果自然pH的蒸馏水、牛奶、可乐中,伊曲康唑溶出度:可乐>牛奶>蒸馏水。从溶解平均最高浓度来看,可乐溶解伊曲康唑的能力约是牛奶的2.36~3.19倍,是蒸馏水的10.37倍。在蛋白质含量相同的情况下,全脂牛奶(脂肪6%)在牛奶中溶出能力最强。结论推荐临床上使用可乐或者全脂牛奶送服伊曲康唑胶囊,可增加药物溶出度,促进胃肠道吸收。 | 徐小茜 汤明海 Sushmita Pradhan 冉玉平 | 2018 | 中国皮肤性病学杂志2018，32，2： | 2 |
| 5 | mLBOA:A Modified Butterfly Optimization Algorithm with Lagrange Interpolation for Global Optimization显示文摘Though the Butterfly Bptimization Algorithm(BOA)has already proved its effectiveness as a robust optimization algorithm,it has certain disadvantages.So,a new variant of BOA,namely mLBOA,is proposed here to improve its performance.The proposed algorithm employs a self-adaptive parameter setting,Lagrange interpolation formula,and a new local search strategy embedded with Levy flight search to enhance its searching ability to make a better trade-off between exploration and exploitation.Also,the fragrance generation scheme of BOA is modified,which leads for exploring the domain effectively for better searching.To evaluate the performance,it has been applied to solve the IEEE CEC 2017 benchmark suite.The results have been compared to that of six state-of-the-art algorithms and five BOA variants.Moreover,various statistical tests,such as the Friedman rank test,Wilcoxon rank test,convergence analysis,and complexity analysis,have been conducted to justify the rank,significance,and complexity of the proposed mLBOA.Finally,the mLBOA has been applied to solve three real-world engineering design problems.From all the analyses,it has been found that the proposed mLBOA is a competitive algorithm compared to other popular state-of-the-art algorithms and BOA variants. | Sushmita Sharma Sanjoy Chakraborty Apu Kumar Saha Sukanta Nama Saroj Kumar Sahoo | 2022 | Journal of Bionic Engineering2022，19，4： | 2 |
| 6 | Adaptive withContextual Constrains for Segmentation of Multi-Spectral MRI显示文摘 | Renjie He Sushmita Datta Balasrinivasa Rao Sajja | 2004 | Conf Proc IEEE Eng Med Biol Soc2004，，3： | 1 |
| 7 | Clustering and its validation in a symbolic framework显示文摘 | Kalyani M Sushmita M | 2003 | Pattern Recognition Letters2003，24，： | 1 |
| 8 | FRBF: A fuzzy radial basis function network 显示文摘 | Sushmita Mitra Jayanta Basak | 2001 | Neural Computing and Applications2001，10，3： | 1 |
| 9 | Gesture recognition:a survey显示文摘 | Mitra Sushmita Achary | 2007 | IEEE Transactions On Systems Man and Cybernetics-Part C:Applications And Reviews2007，37，3： | 1 |
| 10 | Satellite image segmentation with ShadowedC-Means显示文摘 | Sushmita M Partha P | 2011 | Information Sciences2011，181，： | 1 |
| 11 | Dermoscopic clues for sebaceous carcinoma arising in nevus sebaceous显示文摘To the Editor:Sebaceous carcinoma(SC)is a rare cutaneous malignant tumor differentiated from the epithelium lining and arising from the sebaceous gland.[1]Consequently,nevus sebaceous(NS)tends to develop into a benign or malignant neoplasm.[2]Herein,we report dermoscopic findings in a rare case of SC arising in NS with protruding nodule in erosive erythematous surface rapidly arising from yellow pigment plaque resulting in no recurrence.Dermoscopy is a powerful diagnostic tool to generate a preoperative diagnosis. | Sushmita Pradhan Hui Xiao He-Li Yang Yu-Ping Ran | 2020 | Chinese Medical Journal2020，，17： | 1 |
| 12 | Three second chromosome-linked clustered Cyp6genes show differential constitutive and barbital-in-duced expression in DDT-resistant and susceptiblestrains of Drosophila melanogaster显示文摘 | Sushmita M Dombrowski SM Waters LC | 1996 | Gene1996，180，12： | 1 |
| 13 | Understanding practice patterns of glaucoma sub-specialists in India显示文摘AIM:To obtain information on the prevailing practice patterns of glaucoma specialists in India.METHODS:Glaucoma specialists attending the Annual Conference of the Glaucoma Society of India(GSI) were surveyed.This survey,conducted in 2013,was based on an interactive audience response system.RESULTS:The information was obtained from 146 glaucoma specialists.Approximately half(n=83;57%) had ≥10 y of experience in managing glaucoma and were in institutional practice(n=74,51%).Goldmann applanation tonometry was preferred by 103(72%) specialists whilst n=25(17.4%) used non-contact tonometer.Indentation gonioscopy was favoured by two-thirds(n=90,66%) whereas stereoscopic optic disc examination and visual fields using Humphrey perimeter was performed by a majority of the specialists surveyed(n=115,86% and n=114;83% respectively).Nearly three quarter specialists(n=96;72%) preferred optical coherence tomography for imaging.The primary choice for treatment of angle closure disease and primary open angle glaucoma was laser(iridotomy,n=117;93%) and medical management(prostaglandin analogue,n=104;78%),respectively.Approximately only a third of the specialists surveyed(n=37;28%) were performing both trabeculectomy and implantation of a glaucoma drainage device and about half(n=64;47%) were not operating on congenital glaucoma at all.CONCLUSION:This survey has found conformance with preferred practice patterns in several areas of diagnosisand management of glaucoma,but there was diversity in a few areas.The information is a significant step towards improvement of glaucoma care in India,including planning for future strategies. | Nikhil S.Choudhari Vanita Pathak-Ray Sushmita Kaushik Prateep Vyas Ronnie George | 2017 | International Journal of Ophthalmology(English edition)2017，10，10： | 1 |
| 14 | Rough-fuzzy mlp:modular evolution, rule generation, and evaluation显示文摘 | Sankar K P Sushmita M Pabitra M | 2003 | 14IEEE Transactions on Knowledge and Data Engineering2003，15，1： | 1 |
| 15 | Rough fuzzy collaborative clustering显示文摘 | Sushmita Mitra Haider Banka Witold Pedrycz | 2006 | IEEE Trans on Systems Man and Cybernetics Part B: Cybernetics2006，36，4： | 1 |
| 16 | Genetic variations in colorectal cancer risk and clinical outcome显示文摘Colorectal cancer(CRC)has an apparent hereditary component,as evidenced by the well-characterized genetic syndromes and family history associated with the increased risk of this disease.However,in a large fraction of CRC cases,no known genetic syndrome or family history can be identified,suggesting the presence of'missing heritability'in CRC etiology.The genome-wide association study(GWAS)platform has led to the identification of multiple replicable common genetic variants associated with CRC risk.These newly discovered genetic variations might account for a portion of the missing heritability.Here,we summarize the recent GWASs related to newly identified genetic variants associated with CRC risk and clinical outcome.The findings from these studies suggest that there is a lack of understanding of the mechanism of many single nucleotide polymorphisms(SNPs)that are associated with CRC.In addition,the utility of SNPs as prognostic markers of CRC in clinical settings remains to be further assessed.Finally,the currently validated SNPs explain only a small fraction of total heritability in complex-trait diseases like CRC.Thus,the'missing heritability'still needs to be explored further.Future epidemiological and functional investigations of these variants will add to our understanding of CRC pathogenesis,and may ultimately lead to individualized strategies for prevention and treatment of CRC. | Kejin Zhang Jesse Civan Sushmita Mukherjee Fenil Patel Hushan Yang | 2014 | World Journal of Gastroenterology2014，20，15： | 1 |
| 17 | Rough Fuzzy MLP:Knowledge Encoding and Classification显示文摘 | Mohua B SuShmita M Sankar K P | 1998 | IEEE Transaction on Neural Networks1998，6，9： | 1 |
| 18 | Estimating the parameter of the population selected from discrete exponential family显示文摘 | VELLAISAMY P SUSHMITA J | 2008 | Statistics & Probability Letters2008，78，9： | 1 |
| 19 | Application of rough sets in pattern recognition显示文摘 | Sushmita Mitra Haider Banka | 2007 | Trans on Rough Sets2007，7，1： | 1 |
| 20 | Suppression subtractive hybridization coupled with microarray analysis to examine differential expression of genes in virus infected cells显示文摘 | SHIRIN M SUSHMITA S KULJEET K | 2004 | Biol Proced Online2004，，6： | 1 |
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