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| 1 | Deceptive jamming suppression in multistatic radar based on coherent clustering显示文摘This paper proposes a suppression method of the deceptive false target(FT) produced by digital radio frequency memory(DRFM) in a multistatic radar system. The simulated deceptive false targets from DRFM cannot be easily discriminated and suppressed with traditional radar systems. Therefore, multistatic radar has attracted considerable interest as it provides improved performance against deception jamming due to several separated receivers. This paper first investigates the received signal model in the presence of multiple false targets in all receivers of the multistatic radar. Then, obtain the propagation time delays of the false targets based on the cross-correlation test of the received signals in different receivers. In doing so, local-density-based spatial clustering of applications with noise(LDBSCAN) is proposed to discriminate the FTs from the physical targets(PTs) after compensating the FTs time delays, where the FTs are approximately coincident with one position, while PTs possess small dispersion.Numerical simulations are carried out to demonstrate the feasibility and validness of the proposed method. | ABDALLA Ahmed AHMED Mohaned Giess Shokrallah ZHAO Yuan XIONG Ying TANG Bin | 2018 | Journal of Systems Engineering and Electronics2018，29，2： | 12 |
| 2 | Review on evolution and evaluation of asphalt pavement structures and materials显示文摘The purpose of this study was to summarize the wide-range literatures on asphalt pavements, explore the evolution of road pavements, analyze typical asphalt pavement structures, highlight current trends in research and industry, and to recommend future areas of research and development. In this research, road pavement evolution was explored from the earliest roads to the modern pavements. A new method was recommended to categorize asphalt pavement materials into the three large families which may be further sub-divided according to their mechanical parameters. A unified asphalt pavement classification(UAPC) method was proposed and the worldwide asphalt pavements could be divided into six types through the new method. Based o n the UAPC method, 1087 asphalt pavement structures were classified and analyzed to explore the asphalt thickness variation. In order to evaluate asphalt pavement performance, the Chinese design specification was employed for analyzing lives of 29 high-volume pavements and 28 low-volume pavements. Through this research, it was found that:(1) in the past 100 years, asphalt pavement materials and structures had been becoming more and more strong;(2) asphalt layer thicknesses were various from 5 to 60 cm and the overall pavement thicknesses were various from 28 to 160 cm;(3) the long-life pavements in the other countries may become'shorter-life' pavements according to the prediction based on the Chinese specification. | Yu Liu Peifeng Su Miaomiao Li Zhanping You Mohan Zhao | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，5： | 6 |
| 3 | Au nanoclusters suppress chronic lymphocytic leukaemia cells by inhibiting thioredoxin reductase 1 to induce intracellular oxidative stress and apoptosis显示文摘Chronic lymphocytic leukaemia(CLL) is a rare blood cancer that always relapses as refractory disease and eventually leads to death. To date, therapeutic options for CLL patients are scarce and there is an urgent need to develop novel chemotherapeutics that are both effective and safe. Gold-containing compounds induce a lethal oxidative and endoplasmic reticulum stress response in cultured and primary CLL cells via inhibition of thioredoxin reductase(TrxR). However, traditional gold-containing medicines have revealed side effects during clinical applications. Therefore, safer gold-containing drugs are needed to overcome this challenge. In this study, a novel peptide templated gold cluster Au_(25)Sv_9 was synthesized and its therapeutic effect on CLL cells was evaluated. This nanocluster could induce cell apoptosis in MEC-1 cells in a dose-dependent manner which correlated with the uptake amount of clusters in cells.As expected, increasing intracellular reactive oxidative species(ROS) in MEC-1 cells was exhibited with the increase of cluster dosage. Further analyses demonstrated the underlying mechanism that the nanoclusters suppress the activity of TrxR1, increase the level of intracellular ROS, destroy the mitochondrial membrane potential and finally trigger the mitochondrial apoptotic pathway in MEC-1 cells.Furthermore, the direct interaction between Au_(25)Sv_9 clusters and TrxR1 was confirmed for the first time by isothermal titration calorimetry. These findings explored the preclinical efficacy and potential mechanism of gold clusters in CLL therapy and provided a fundamental reference for the development of other novel gold-containing chemotherapeutics to treat CLL. | Qiong Li Qing Yuan Mohan Zhao Yawen Yao Liang Gao Ru Liu Yaling Wang Yong Gong Fuping Gao Xueyun Cao | 2017 | Science Bulletin2017，62，8： | 5 |
| 4 | Connected K-target coverageproblem in wireless sensor networks with different observation sce-narios显示文摘 | ZHAO Qun Mohan Gurusamy | 2008 | Computer Networks2008，52，11： | 1 |
| 5 | Detection of human Faces in a compressed domain for video stratification 显示文摘 | Tat-SengChua Yunlong Zhao Mohan S Kankanhalli | 2002 | The VisualComputer(S0178-2789)2002，18，2： | 1 |
| 6 | Femtosecond laser fabrication of nanograting-based distributed fiber sensors for extreme environmental applications显示文摘The femtosecond laser has emerged as a powerful tool for micro-and nanoscale device fabrication. Through nonlinear ionization processes, nanometer-sized material modifications can be inscribed in transparent materials for device fabrication. This paper describes femtosecond precision inscription of nanograting in silica fiber cores to form both distributed and point fiber sensors for sensing applications in extreme environmental conditions. Through the use of scanning electron microscope imaging and laser processing optimization,high-temperature stable, Type II femtosecond laser modifications were continuously inscribed,point by point, with only an insertion loss at 1 d B m~(-1) or 0.001 d B per point sensor device.High-temperature performance of fiber sensors was tested at 1000℃, which showed a temperature fluctuation of ±5.5℃ over 5 days. The low laser-induced insertion loss in optical fibers enabled the fabrication of a 1.4 m, radiation-resilient distributed fiber sensor. The in-pile testing of the distributed fiber sensor further showed that fiber sensors can execute stable and distributed temperature measurements in extreme radiation environments. Overall, this paper demonstrates that femtosecond-laser-fabricated fiber sensors are suitable measurement devices for applications in extreme environments. | Mohan Wang Kehao Zhao Jingyu Wu Yuqi Li Yang Yang Sheng Huang Jieru Zhao Thomas Tweedle David Carpenter Guiqiu Zheng Qingxu Yu Kevin P Chen | 2021 | International Journal of Extreme Manufacturing2021，3，2： | 1 |
| 7 | Lifetime maximization for connected target coverage in wireless sensor networks显示文摘 | Qun Zhao Mohan Gurusamy | 2008 | IEEE/ACM Transactions on Networking (TON)2008，，6： | 1 |
| 8 | Evaluation of respiratory-induced target motion for esophageal tumors at the gastroesophageal junction显示文摘 | Kuai-le Zhao Zhongxing Liao M. Kara Bucci Ritsuko Komaki James D. Cox Zhiqian H. Yu Lifei Zhang Radhe Mohan Lei Dong | 2007 | Radiotherapy and Oncology2007，，3： | 1 |
| 9 | MicroRNA-30d in- duces insulin transcription factor MafA and insulin produc- tion by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic beta-cells 显示文摘 | Zhao X Mohan R Ozcan S | 2012 | J Biol Chem2012，287，31： | 1 |
| 10 | Protocatechuic acid and quercetin attenuate ETEC-caused IPEC-1 cell inflammation and injury associated with inhibition of necroptosis and pyroptosis signaling pathways显示文摘Background:Necroptosis and pyroptosis are newly identified forms of programmed cell death,which play a vital role in development of many gastrointestinal disorders.Although plant polyphenols have been reported to protect intestinal health,it is still unclear whether there is a beneficial role of plant polyphenols in modulating necroptosis and pyroptosis in intestinal porcine epithelial cell line(IPEC-1)infected with enterotoxigenic Escherichia coli(ETEC)K88.This research was conducted to explore whether plant polyphenols including protocatechuic acid(PCA)and quercetin(Que),attenuated inflammation and injury of IPEC-1 caused by ETEC K88 through regulating necroptosis and pyroptosis signaling pathways.Methods:IPEC-1 cells were treated with PCA(40μmol/L)or Que(10μmol/L)in the presence or absence of ETEC K88.Results:PCA and Que decreased ETEC K88 adhesion and endotoxin level(P<0.05)in cell supernatant.PCA and Que increased cell number(P<0.001)and decreased lactate dehydrogenases(LDH)activity(P<0.05)in cell supernatant after ETEC infection.PCA and Que improved transepithelial electrical resistance(TEER)(P<0.001)and reduced fluorescein isothiocyanate-labeled dextran(FD4)flux(P<0.001),and enhanced membrane protein abundance of occludin,claudin-1 and ZO-1(P<0.05),and rescued distribution of these tight junction proteins(P<0.05)after ETEC infection.PCA and Que also declined cell necrosis ratio(P<0.05).PCA and Que reduced mRNA abundance and concentration of tumor necrosis factor-α(TNF-α),interleukin(IL)-6 and IL-8(P<0.001),and down-regulated gene expression of toll-like receptors 4(TLR4)and its downstream signals(P<0.001)after ETEC infection.PCA and Que down-regulated protein abundance of total receptor interacting protein kinase 1(t-RIP1),phosphorylated-RIP1(p-RIP1),p-RIP1/t-RIP1,t-RIP3,p-RIP3,mixed lineage kinase domain-like protein(MLKL),p-MLKL,dynamin-related protein 1(DRP1),phosphoglycerate mutase 5(PGAM5)and high mobility group box 1(HMGB1)(P<0.05)after ETEC infection.Moreover,PCA and Que reduced protein abundance of nod-like receptor protein 3(NLRP3),nod-like receptors family CARD domain-containing protein 4(NLRC4),apoptosis-associated speck-like protein containing a CARD(ASC),gasdermin D(GSDMD)and caspase-1(P<0.05)after ETEC infection.Conclusions:In general,our data suggest that PCA and Que are capable of attenuating ETEC-caused intestinal inflammation and damage via inhibiting necroptosis and pyroptosis signaling pathways. | Kan Xiao Mohan Zhou Qingqing Lv Pengwei He Xu Qin Dan Wang Jiangchao Zhao Yulan Liu | 2023 | Journal of Animal Science and Biotechnology2023，14，4： | 0 |
| 11 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 12 | Mapping Multi-factor-mediated Chromatin Interactions to Assess Dysregulation of Lung Cancer-related Genes显示文摘Studies on the lung cancer genome are indispensable for developing a cure for lung cancer.Whole-genome resequencing,genome-wide association studies,and transcriptome sequencing have greatly improved our understanding of the cancer genome.However,dysregulation of longrange chromatin interactions in lung cancer remains poorly described.To better understand the three-dimensional(3D)genomic interaction features of the lung cancer genome,we used the A549 cell line as a model system and generated high-resolution chromatin interactions associated with RNA polymerase II(RNAPII),CCCTC-binding factor(CTCF),enhancer of zeste homolog 2(EZH2),and histone 3 lysine 27 trimethylation(H3K27me3)using long-read chromatin interaction analysis by paired-end tag sequencing(ChIA-PET).Analysis showed that EZH2/H3K27me3-mediated interactions further repressed target genes,either through loops or domains,and their distributions along the genome were distinct from and complementary to those associated with RNAPII.Cancer-related genes were highly enriched with chromatin interactions,and chromatin interactions specific to the A549 cell line were associated with oncogenes and tumor suppressor genes,such as additional repressive interactions on FOXO4 and promoter–promoter interactions between NF1 and RNF135.Knockout of an anchor associated with chromatin interactions reversed the dysregulation of cancer-related genes,suggesting that chromatin interactions are essential for proper expression of lung cancer-related genes.These findings demonstrate the 3D landscape and gene regulatory relationships of the lung cancer genome. | Yan Zhang Jingwen Zhang Wei Zhang Mohan Wang Shuangqi Wang Yao Xu Lun Zhao Xingwang Li Guoliang Li | 2023 | Genomics, Proteomics & Bioinformatics2023，21，3： | 0 |
| 13 | Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy显示文摘Despite the remarkable success of immune checkpoint inhibitors(ICIs),primary resistance to ICIs causes only subsets of patients to achieve durable responses due to the complex tumor microenvironment(TME).Oncolytic viruses(OVs)can overcome the immunosuppressive TME and promote systemic antitumor immunity in hosts.Engineered OVs armed with ICIs would likely have improved effectiveness as a cancer therapy.According to the diverse immune cell landscapes among different types of tumors,we rationally and precisely generated three recombinant oncolytic adenoviruses(OAds):OAd-SIRPα-Fc,OAd-Siglec10-Fc and OAd-TIGIT-Fc.These viruses were designed to locally deliver SIRPα-Fc,Siglec10-Fc or TIGIT-Fc fusion proteins recognizing CD47,CD24 or CD155,respectively,in the TME to achieve enhanced antitumor effects.Our results suggested that OAd-SIRPα-Fc and OAd-Siglec10-Fc both showed outstanding efficacy in tumor suppression of macrophage-dominated tumors,while OAd-TIGIT-Fc showed the best antitumor immunity in CD8+T-cell-dominated tumors.Importantly,the recombinant OAds activated an inflammatory immune response and generated long-term antitumor memory.In addition,the combination of OAd-Siglec10-Fc with anti-PD-1 significantly enhanced the antitumor effect in a 4T1 tumor model by remodeling the TME.In summary,rationally designed OAds expressing ICIs tailored to the immune cell landscape in the TME can precisely achieve tumor-specific immunotherapy of cancer. | Daoyuan Xie Yaomei Tian Die Hu Yuanda Wang Yuling Yang Bailing Zhou Rui Zhang Zhixiang Ren Mohan Liu Jie Xu Chunyan Dong Binyan Zhao Li Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，12： | 0 |
| 14 | Novel Autoantibodies Related to Cell Death and DNA Repair Pathways in Systemic Lupus Erythematosus显示文摘Systemic lupus erythematosus(SLE)is a complex autoimmune syndrome characterized by various co-existing autoantibodies(autoAbs)in patients’blood.However,the full spectrum of autoAbs in SLE has not been comprehensively elucidated.In this study,a commercial platform bearing 9400 antigens(ProtoArray)was used to identify autoAbs that were significantly elevated in the sera of SLE patients.By comparing the autoAb profiles of SLE patients with those of healthy controls,we identified 437 IgG and 1213 IgM autoAbs that the expression levels were significantly increased in SLE(P<0.05).Use of the ProtoArray platform uncovered over 300 novel autoAbs targeting a broad range of nuclear,cytoplasmic,and membrane antigens.Molecular interaction network analysis revealed that the antigens targeted by the autoAbs were most significantly enriched in cell death,cell cycle,and DNA repair pathways.A group of autoAbs associated with cell apoptosis and DNA repair function,including those targeting APEX1,AURKA,POLB,AGO1,HMGB1,IFIT5,MAPKAPK3,PADI4,RGS3,SRP19,UBE2S,and VRK1,were further validated by ELISA and Western blot in a larger cohort.In addition,the levels of autoAbs against APEX1,HMGB1,VRK1,AURKA,PADI4,and SRP19 were positively correlated with the level of anti-dsDNA in SLE patients.Comprehensive autoAb screening has identified novel autoAbs,which may shed light on potential pathogenic pathways leading to lupus. | Hui Luo Ling Wang Ding Bao Li Wang Hongjun Zhao Yun Lian Mei Yan Chandra Mohan Quan-Zhen Li | 2019 | Genomics, Proteomics & Bioinformatics2019，17，3： | 0 |
| 15 | Sub-percent precision measurement of neutrino oscillation parameters with JUNO显示文摘JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the experiment.The sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite detector.It is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data collection.In the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering hypothesis.The new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters. | Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem 安丰鹏 安琪 Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste 白伟东 Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩 蔡啸 蔡严克 蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚 曹国富 曹俊 Rossella Caruso Cédric Cerna Chi Chan 常劲帆 Yun Chang 陈国明 陈平平 Po-An Chen 陈少敏 Xurong Chen 陈义学 陈羽 陈志源 陈梓康 程捷 程雅苹 Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille 邓智 邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich Marcos Dracos Frédéric Druillole 杜然 杜书先 Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan 樊磊 方建 方文兴 Marco Fargetta Dmitry Fedoseev 费政勇 Li-Cheng Feng 冯启春 Richard Ford Amélie Fournier 甘浩男 高峰 Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar 龚光华 宫辉 Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov 顾旻皓 谷肖飞 古宇 关梦云 管宇铎 Nunzio Guardone 郭聪 郭竞渊 郭万磊 Xinheng Guo 郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han 何苗 Wei He Tobias Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强 侯少静 Yee Hsiung Bei-Zhen Hu 胡航 Jianrun Hu 胡俊 胡守扬 胡涛 胡宇翔 胡焯钧 黄桂鸿 黄翰雄 黄凯旋 黄文昊 Xin Huang 黄性涛 黄永波 惠加琪 霍雷 霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Ignacio Jeria 季筱璐 贾慧慧 贾俊基 蹇司玉 蒋荻 蒋炜 江晓山 荆小平 Cécile Jollet Jari Joutsenvaara Leonidas Kalousis Philipp Kampmann 康丽 Rebin Karaparambil Narine Kazarian Amina Khatun Khanchai Khosonthongkee Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Victor Lebrin Frederic Lefevre 雷瑞庭 Rupert Leitner Jason Leung Daozheng Li 李德民 李飞 李福乐 李高嵩 Huiling Li 李梦朝 李民 李楠 Nan Li 李清江 李茹慧 李瑞 黎山峰 李涛 李腾 李卫东 李卫国 李笑梅 李小男 李兴隆 李仪 李依宸 李玉峰 Zepeng Li 李兆涵 李志兵 李紫源 李宗海 梁浩 梁昊 廖佳军 Ayut Limphirat Guey-Lin Lin 林盛鑫 林韬 凌家杰 Ivano Lippi 刘芳 刘海东 刘昊天 刘宏邦 刘红娟 刘洪涛 Hui Liu 刘江来 刘金昌 刘敏 刘倩 刘钦 Runxuan Liu 刘树彬 刘术林 刘小伟 刘熙文 Yan Liu Yunzhe Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo 陆川 路浩奇 陆景彬 吕军光 路书祥 Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Arslan Lukanov Daibin Luo Fengjiao Luo 罗光 罗舒 罗武鸣 罗晓杰 Vladimir Lyashuk 马帮争 马冰 马秋梅 马斯 马骁妍 马续波 Jihane Maalmi 麦景宇 Yury Malyshkin Roberto Carlos Mandujano Fabio Mantovani Francesco Manzali 冒鑫 冒亚军 Stefano M.Mari Filippo Marini Cristina Martellini Gisele Martin-Chassard Agnese Martini Matthias Mayer Davit Mayilyan Ints Mednieks Artur Meinusch 孟月 Anselmo Meregaglia Emanuela Meroni David Meyhö Mauro Mezzetto Jonathan Miller Lino Miramonti Marta Colomer Molla Paolo Montini Michele Montuschi Axel Müller Massimiliano Nastasi Dmitry V.Naumov Elena Naumova Diana Navas-Nicolas Igor Nemchenok Minh Thuan Nguyen Thi 宁飞鹏 宁哲 Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Rainer Othegraven Alessandro Paoloni Sergio Parmeggiano 裴亚田 Luca Pelicci Nicomede Pelliccia 彭安国 彭海平 彭宇 彭昭缘 Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Oliver Pilarczyk Luis Felipe Piñeres Artyom Popov Pascal Poussot Ezio Previtali 齐法制 祁鸣 钱森 钱小辉 钱圳 乔浩 秦中华 丘寿康 Gioacchino Ranucci Neill Raper Reem Rasheed Alessandra Re Henning Rebber Abdel Rebii Mariia Redchuk 任斌 任杰 Barbara Ricci Mariam Rifai Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec 阮锡超 Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Simone Sanfilippo Anut Sangka Utane Sawangwit Julia Sawatzki Michaela Schever Cédric Schwab Konstantin Schweizer Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Zhuang Shao Vladislav Sharov Arina Shaydurova 石京燕 史娅楠 Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Sergey Sokolov Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov OndřejŠrámek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin 苏俊 孙世峰 孙希磊 孙勇杰 孙永昭 孙正阳 Narumon Suwonjandee Michal Szelezniak 唐健 唐强 唐泉 唐晓 Vidhya Thara Hariharan Eric Theisen Alexander Tietzsch Igor Tkachev Tomas Tmej Marco Danilo Claudio Torri Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Alexandros Tsagkarakis Cristina Tuve Nikita Ushakov Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cornelius Moritz Vollbrecht Cristina Volpe Katharina Von Sturm Vit Vorobel Dmitriy Voronin Lucia Votano Pablo Walker 王彩申 Chung-Hsiang Wang 王恩 王国利 王坚 王俊 汪璐 Meifen Wang 王孟 Meng Wang 王瑞光 王思广 王维 王为 王文帅 王玺 王湘粤 王仰夫 王耀光 王毅 王义 王贻芳 王元清 Yuman Wang 王喆 王铮 王志民 Zongyi Wang Apimook Watcharangkool 魏微 魏巍 韦雯露 魏亚东 温凯乐 温良剑 Christopher Wiebusch 黄振辉 Bjoern Wonsak 吴帝儒 吴群 吴智 Michael Wurm Jacques Wurtz Christian Wysotzki 习宇飞 夏冬梅 Xiang Xiao 谢小川 谢宇广 Zhangquan Xie 辛钊 邢志忠 续本达 徐程 徐东莲 徐繁荣 许杭锟 徐吉磊 徐晶 徐美杭 徐音 闫保军 Taylor Yan Wenqi Yan 严雄波 Yupeng Yan 杨长根 杨成峰 Huan Yang 杨洁 杨雷 杨晓宇 Yifan Yang 姚海峰 叶佳璇 叶梅 叶子平 Frédéric Yermia Na Yin 尤郑昀 俞伯祥 余炽业 喻纯旭 余泓钊 于淼 于向辉 于泽源 于泽众 袁岑溪 袁成卓 袁影 袁振雄 岳保彪 Noman Zafar Vitalii Zavadskyi 曾珊 曾婷轩 曾裕达 占亮 张爱强 张斌 张斌婷 张飞洋 Guoqing Zhang 张宏浩 张家梁 张家文 张杰 Jin Zhang 张景波 张金楠 Mohan Zhang 张鹏 张清民 张石其 张澍 张涛 张晓梅 张鑫 张玄同 Xueyao Zhang 张银鸿 张易于 张永鹏 张宇 张圆圆 张玉美 张振宇 张志坚 Fengyi Zhao 赵洁 赵荣 赵润泽 赵书俊 Dongqin Zheng 郑华 郑阳恒 Weirong Zhong 周静 周莉 周楠 周顺 周彤 周详 朱江 朱景森 朱康甫 朱科军 朱志航 庄博 庄红林 宗亮 邹佳恒 | 2022 | Chinese Physics C2022，46，12： | 0 |
| 16 | A Machine Learning Made Catalog of FR-Ⅱ Radio Galaxies from the FIRST Survey显示文摘We present an independent catalog(FRIIRGcat)of 45,241 Fanaroff–Riley TypeⅡ(FR-Ⅱ)radio galaxies compiled from the Very Large Array Faint Images of the Radio Sky at Twenty-centimeters(FIRST)survey and employed the deep learning method.Among them,optical and/or infrared counterparts are identified for 41,425 FR-Ⅱs.This catalog spans luminosities 2.63×10^(22)≤L_(rad)≤6.76×10^(29)W Hz^(-1)and redshifts up to z=5.01.The spectroscopic classification indicates that there are 1431 low-excitation radio galaxies and 260 high-excitation radio galaxies.Among the spectroscopically identified sources,black hole masses are estimated for 4837 FR-Is,which are in 10^(7.5)■M_(BH)■10^(9.5)M_(⊙).Interestingly,this catalog reveals a couple of giant radio galaxies(GRGs),which are already in the existing GRG catalog,confirming the efficiency of this FR-I catalog.Furthermore,284new GRGs are unveiled in this new FR-I sample;they have the largest projected sizes ranging from 701 to1209 kpc and are located at redshifts 0.31 | Bao-Qiang Lao Xiao-Long Yang Sumit Jaiswal Prashanth Mohan Xiao-Hui Sun Sheng-Li Qin Ru-Shuang Zhao | 2024 | Research in Astronomy and Astrophysics2024，24，3： | 0 |
| 17 | α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure显示文摘The sarcomeric interaction ofα-myosin heavy chain(α-MHC)with Titin is vital for cardiac structure and contraction.However,the mechanism regulating this interaction in normal and failing hearts remains unknown.Lactate is a crucial energy substrate of the heart.Here,we identify thatα-MHC undergoes lactylation on lysine 1897 to regulate the interaction ofα-MHC with Titin.We observed a reduction ofα-MHC K1897 lactylation in mice and patients with heart failure.Loss of K1897 lactylation inα-MHC K1897R knock-in mice reducesα-MHC–Titin interaction and leads to impaired cardiac structure and function.Furthermore,we identified that p300 and Sirtuin 1 act as the acyltransferase and delactylase ofα-MHC,respectively.Decreasing lactate production by chemical or genetic manipulation reducesα-MHC lactylation,impairsα-MHC–Titin interaction and worsens heart failure.By contrast,upregulation of the lactate concentration by administering sodium lactate or inhibiting the pivotal lactate transporter in cardiomyocytes can promoteα-MHC K1897 lactylation andα-MHC–Titin interaction,thereby alleviating heart failure.In conclusion,α-MHC lactylation is dynamically regulated and an important determinant of overall cardiac structure and function.Excessive lactate efflux and consumption by cardiomyocytes may decrease the intracellular lactate level,which is the main cause of reducedα-MHC K1897 lactylation during myocardial injury.Our study reveals that cardiac metabolism directly modulates the sarcomeric structure and function through lactate-dependent modification ofα-MHC. | Naijin Zhang Ying Zhang Jiaqi Xu Pengbo Wang Boquan Wu Saien Lu Xinxin Lu Shilong You Xinyue Huang Mohan Li Yuanming Zou Mengke Liu Yuanhui Zhao Guozhe Sun Wenbin Wang Danxi Geng Jingwei Liu Liu Cao Yingxian Sun | 2023 | Cell Research2023，33，9： | 0 |
| 18 | Differentiation of Expression Profiles of SREBF1 and SREBF2 Gene in Chicken显示文摘Sterol regulatory element-binding factor-1 and-2(SREBF1 and SREBF2)are important transcription factors involved in the regulating lipid homeostasis.Based on the essential role of SREBF1 and SREBF2,we measured the mRNA expression levels of the two genes in six various tissues at different growth points.Our results showed that the SREBF1 and SREBF2 were expressed in all six tissues examined in Erlang mountainous chicken(SD02)at 42 d,and were expressed abundantly in the uropygial gland and liver,with relatively lowest levels of expression in the abdominal fat,sebum cutaneum and leg muscle.The expression ratio of SREBF1 and SREBF2 in breast muscle,leg muscle,sebum cutaneum and uropygial gland exhibited a'decline-rise'trend.However,in liver,the expression ratio of these two genes exhibited a'decline-rise-decline'trend.Meanwhile,the expression level of SREBF1 gene of all tissues was lower than that of SREBF2 except for uropygial gland.The findings will provide important references for further function investigation of the two genes involved in fat deposition in chickens. | Mohan QIU Zengrong ZHANG Chunlin YU Xiaosong JIANG Huarui DU Qingyun LI Hengyong XU Huadong YIN Xiaoling ZHAO Qing ZHU Yan WANG Chaowu YANG | 2020 | Agricultural Biotechnology2020，9，5： | 0 |
| 19 | Fungal diversity notes 1151-1276:taxonomic and phylogenetic contributions on genera and species of fungal taxa显示文摘Fungal diversity notes is one of the important journal series of fungal taxonomy that provide detailed descriptions and illustrations of new fungal taxa,as well as providing new information of fungal taxa worldwide.This article is the 11th contribution to the fungal diversity notes series,in which 126 taxa distributed in two phyla,six classes,24 orders and 55 families are described and illustrated.Taxa in this study were mainly collected from Italy by Erio Camporesi and also collected from China,India and Thailand,as well as in some other European,North American and South American countries.Taxa described in the present study include two new families,12 new genera,82 new species,five new combinations and 25 new records on new hosts and new geographical distributions as well as sexual-asexual reports.The two new families are Eriomycetaceae(Dothideomycetes,family incertae sedis)and Fasciatisporaceae(Xylariales,Sordariomycetes).The twelve new genera comprise Bhagirathimyces(Phaeosphaeriaceae),Camporesiomyces(Tubeufiaceae),Eriocamporesia(Cryphonectriaceae),Eriomyces(Eriomycetaceae),Neomonodictys(Pleurotheciaceae),Paraloratospora(Phaeosphaeriaceae),Paramonodictys(Parabambusicolaceae),Pseudoconlarium(Diaporthomycetidae,genus incertae sedis),Pseudomurilentithecium(Lentitheciaceae),Setoapiospora(Muyocopronaceae),Srinivasanomyces(Vibrisseaceae)and Xenoanthostomella(Xylariales,genera incertae sedis).The 82 new species comprise Acremonium chiangraiense,Adustochaete nivea,Angustimassarina camporesii,Bhagirathimyces himalayensis,Brunneoclavispora camporesii,Camarosporidiella camporesii,Camporesiomyces mali,Camposporium appendiculatum,Camposporium multiseptatum,Camposporium septatum,Canalisporium aquaticium,Clonostachys eriocamporesiana,Clonostachys eriocamporesii,Colletotrichum hederiicola,Coniochaeta vineae,Conioscypha verrucosa,Cortinarius ainsworthii,Cortinarius aurae,Cortinarius britannicus,Cortinarius heatherae,Cortinarius scoticus,Cortinarius subsaniosus,Cytospora fusispora,Cytospora rosigena,Diaporthe camporesii,Diaporthe nigra,Diatrypella yunnanensis,Dictyosporium muriformis,Didymella camporesii,Diutina bernali,Diutina sipiczkii,Eriocamporesia aurantia,Eriomyces heveae,Ernakulamia tanakae,Falciformispora uttaraditensis,Fasciatispora cocoes,Foliophoma camporesii,Fuscostagonospora camporesii,Helvella subtinta,Kalmusia erioi,Keissleriella camporesiana,Keissleriella camporesii,Lanspora cylindrospora,Loratospora arezzoensis,Mariannaea atlantica,Melanographium phoenicis,Montagnula camporesii,Neodidymelliopsis camporesii,Neokalmusia kunmingensis,Neoleptosporella camporesiana,Neomonodictys muriformis,Neomyrmecridium guizhouense,Neosetophoma camporesii,Paraloratospora camporesii,Paramonodictys solitarius,Periconia palmicola,Plenodomus triseptatus,Pseudocamarosporium camporesii,Pseudocercospora maetaengensis,Pseudochaetosphaeronema kunmingense,Pseudoconlarium punctiforme,Pseudodactylaria camporesiana,Pseudomurilentithecium camporesii,Pseudotetraploa rajmachiensis,Pseudotruncatella camporesii,Rhexocercosporidium senecionis,Rhytidhysteron camporesii,Rhytidhysteron erioi,Septoriella camporesii,Setoapiospora thailandica,Srinivasanomyces kangrensis,Tetraploa dwibahubeeja,Tetraploa pseudoaristata,Tetraploa thrayabahubeeja,Torula camporesii,Tremateia camporesii,Tremateia lamiacearum,Uzbekistanica pruni,Verruconis mangrovei,Wilcoxina verruculosa,Xenoanthostomella chromolaenae and Xenodidymella camporesii.The five new combinations are Camporesiomyces patagoniensis,Camporesiomyces vaccinia,Camposporium lycopodiellae,Paraloratospora gahniae and Rhexocercosporidium microsporum.The 22 new records on host and geographical distribution comprise Arthrinium marii,Ascochyta medicaginicola,Ascochyta pisi,Astrocystis bambusicola,Camposporium pellucidum,Dendryphiella phitsanulokensis,Diaporthe foeniculina,Didymella macrostoma,Diplodia mutila,Diplodia seriata,Heterosphaeria patella,Hysterobrevium constrictum,Neodidymelliopsis ranunculi,Neovaginatispora fuckelii,Nothophoma quercina,Occultibambusa bambusae,Phaeosphaeria chinensis,Pseudopestalotiopsis theae,Pyxine berteriana,Tetraploa sasicola,Torula gaodangensis and Wojnowiciella dactylidis.In addition,the sexual morphs of Dissoconium eucalypti and Phaeosphaeriopsis pseudoagavacearum are reported from Laurus nobilis and Yucca gloriosa in Italy,respectively.The holomorph of Diaporthe cynaroidis is also reported for the first time. | Kevin DHyde Yang Dong Rungtiwa Phookamsak Rajesh Jeewon DJayarama Bhat EBGareth Jones Ning‑Guo Liu Pranami DAbeywickrama Ausana Mapook Deping Wei Rekhani HPerera Ishara SManawasinghe Dhandevi Pem Digvijayini Bundhun Anuruddha Karunarathna Anusha HEkanayaka Dan‑Feng Bao Junfu Li Milan CSamarakoon Napalai Chaiwan Chuan‑Gen Lin Kunthida Phutthacharoen Sheng‑Nan Zhang Indunil CSenanayake Ishani DGoonasekara Kasun MThambugala Chayanard Phukhamsakda Danushka STennakoon Hong‑Bo Jiang Jing Yang Ming Zeng Naruemon Huanraluek Jian‑Kui(Jack)Liu Subodini NWijesinghe Qing Tian Saowaluck Tibpromma Rashika SBrahmanage Saranyaphat Boonmee Shi‑Ke Huang Vinodhini Thiyagaraja Yong‑Zhong Lu Ruvishika SJayawardena Wei Dong Er‑Fu Yang Sanjay KSingh Shiv Mohan Singh Shiwali Rana Sneha SLad Garima Anand Bandarupalli Devadatha MNiranjan VVenkateswara Sarma Kare Liimatainen 馻‑ Tuula Niskanen Andy Overall Renato Lúcio Mendes Alvarenga Tatiana Baptista Gibertoni Walter PPfliegler EnikőHorváth Alexandra Imre Amanda Lucia Alves Ana Carla da Silva Santos Patricia Vieira Tiago Timur SBulgakov Dhanushaka NWanasinghe Ali HBahkali Mingkwan Doilom Abdallah MElgorban Sajeewa SNMaharachchikumbura Kunhiraman CRajeshkumar Danny Haelewaters Peter EMortimer Qi Zhao Saisamorn Lumyong Jianchu Xu Jun Sheng | 2020 | Fungal Diversity2020，，1： | 0 |
| 20 | A Cosmic Microscope to Probe the Universe from Present to Cosmic Dawn:Dual-element Lowfrequency Space VLBI Observatory显示文摘A space-based Very Long Baseline Interferometry (VLBI) program, named as the Cosmic Microscope, is proposed to involve dual VLBI telescopes in the space working together with giant ground-based telescopes (e.g., Square Kilometre Array, FAST, Arecibo) to image the low radio frequency Universe with the purpose of unraveling the compact structure of cosmic constituents including supermassive black holes and binaries, pulsars, astronomical masers and the underlying source, and exoplanets amongst others. The operational frequency bands are 30, 74, 330 and 1670 MHz, supporting broad science areas. The mission plans to launch two 30-m-diameter radio telescopes into 2 000 km×90 000 km elliptical orbits. The two telescopes can work in flexibly diverse modes,(i) Space-ground VLBI. The maximum space-ground baseline length is about100 000 km; it provides a high-dynamic-range imaging capacity with unprecedented high resolutions at low frequencies (0.3 mas at 1.67 GHz and 20 mas at 30 MHz) enabling studies of exoplanets and supermassive black hole binaries (which emit nanoHz gravitational waves),(ii) Space-space single-baseline VLBI. This unique baseline enables the detection of flaring hydroxyl masers, and more precise position measurement of pulsars and radio transients at mas level.(iii) Single dish mode, where each telescope can be used to monitor transient bursts and rapidly trigger follow-up VLBI observations. The large space telescope will also contribute in measuring and constraining the total angular power spectrum from the Epoch of Reionization. In short, the Cosmic Microscope offers astronomers the opportunity to conduct novel, frontier science. | AN Tao JAISWAL Sumit MOHAN Prashanth ZHAO Zhen LAO Baoqiang | 2019 | 空间科学学报2019，39，2： | 0 |
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