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| 1 | Review on evolution and evaluation of asphalt pavement structures and materials显示文摘The purpose of this study was to summarize the wide-range literatures on asphalt pavements, explore the evolution of road pavements, analyze typical asphalt pavement structures, highlight current trends in research and industry, and to recommend future areas of research and development. In this research, road pavement evolution was explored from the earliest roads to the modern pavements. A new method was recommended to categorize asphalt pavement materials into the three large families which may be further sub-divided according to their mechanical parameters. A unified asphalt pavement classification(UAPC) method was proposed and the worldwide asphalt pavements could be divided into six types through the new method. Based o n the UAPC method, 1087 asphalt pavement structures were classified and analyzed to explore the asphalt thickness variation. In order to evaluate asphalt pavement performance, the Chinese design specification was employed for analyzing lives of 29 high-volume pavements and 28 low-volume pavements. Through this research, it was found that:(1) in the past 100 years, asphalt pavement materials and structures had been becoming more and more strong;(2) asphalt layer thicknesses were various from 5 to 60 cm and the overall pavement thicknesses were various from 28 to 160 cm;(3) the long-life pavements in the other countries may become'shorter-life' pavements according to the prediction based on the Chinese specification. | Yu Liu Peifeng Su Miaomiao Li Zhanping You Mohan Zhao | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，5： | 6 |
| 2 | Au nanoclusters suppress chronic lymphocytic leukaemia cells by inhibiting thioredoxin reductase 1 to induce intracellular oxidative stress and apoptosis显示文摘Chronic lymphocytic leukaemia(CLL) is a rare blood cancer that always relapses as refractory disease and eventually leads to death. To date, therapeutic options for CLL patients are scarce and there is an urgent need to develop novel chemotherapeutics that are both effective and safe. Gold-containing compounds induce a lethal oxidative and endoplasmic reticulum stress response in cultured and primary CLL cells via inhibition of thioredoxin reductase(TrxR). However, traditional gold-containing medicines have revealed side effects during clinical applications. Therefore, safer gold-containing drugs are needed to overcome this challenge. In this study, a novel peptide templated gold cluster Au_(25)Sv_9 was synthesized and its therapeutic effect on CLL cells was evaluated. This nanocluster could induce cell apoptosis in MEC-1 cells in a dose-dependent manner which correlated with the uptake amount of clusters in cells.As expected, increasing intracellular reactive oxidative species(ROS) in MEC-1 cells was exhibited with the increase of cluster dosage. Further analyses demonstrated the underlying mechanism that the nanoclusters suppress the activity of TrxR1, increase the level of intracellular ROS, destroy the mitochondrial membrane potential and finally trigger the mitochondrial apoptotic pathway in MEC-1 cells.Furthermore, the direct interaction between Au_(25)Sv_9 clusters and TrxR1 was confirmed for the first time by isothermal titration calorimetry. These findings explored the preclinical efficacy and potential mechanism of gold clusters in CLL therapy and provided a fundamental reference for the development of other novel gold-containing chemotherapeutics to treat CLL. | Qiong Li Qing Yuan Mohan Zhao Yawen Yao Liang Gao Ru Liu Yaling Wang Yong Gong Fuping Gao Xueyun Cao | 2017 | Science Bulletin2017，62，8： | 5 |
| 3 | Long Short Term Memory Networks Based Anomaly Detection for KPIs显示文摘In real-world many internet-based service companies need to closely monitor large amounts of data in order to ensure stable operation of their business.However,anomaly detection for these data with various patterns and data quality has been a great challenge,especially without labels.In this paper,we adopt an anomaly detection algorithm based on Long Short-Term Memory(LSTM)Network in terms of reconstructing KPIs and predicting KPIs.They use the reconstruction error and prediction error respectively as the criteria for judging anomalies,and we test our method with real data from a company in the insurance industry and achieved good performance. | Haiqi Zhu Fanzhi Meng Seungmin Rho Mohan Li Jianyu Wang Shaohui Liu Feng Jiang | 2019 | Computers, Materials & Continua2019，，8： | 2 |
| 4 | Impact of switching frequencies on the TID response of SiC power MOSFETs显示文摘Different switching frequencies are required when SiC metal-oxide-semiconductor field-effect transistors(MOSFETs)are switching in a space environment.In this study,the total ionizing dose(TID)responses of SiC power MOSFETs are investigated under different switching frequencies from 1 kHz to 10 MHz.A significant shift was observed in the threshold voltage as the frequency increased,which resulted in premature failure of the drain-source breakdown voltage and drain-source leakage current.The degradation is attributed to the high activation and low recovery rates of traps at high frequencies.The results of this study suggest that a targeted TID irradiation test evaluation method can be developed according to the actual switching frequency of SiC power MOSFETs. | Sheng Yang Xiaowen Liang Jiangwei Cui Qiwen Zheng Jing Sun Mohan Liu Dang Zhang Haonan Feng Xuefeng Yu Chuanfeng Xiang Yudong Li Qi Guo | 2021 | Journal of Semiconductors2021，42，8： | 2 |
| 5 | Adversarial Attacks on Content-Based Filtering Journal Recommender Systems显示文摘Recommender systems are very useful for people to explore what they really need.Academic papers are important achievements for researchers and they often have a great deal of choice to submit their papers.In order to improve the efficiency of selecting the most suitable journals for publishing their works,journal recommender systems(JRS)can automatically provide a small number of candidate journals based on key information such as the title and the abstract.However,users or journal owners may attack the system for their own purposes.In this paper,we discuss about the adversarial attacks against content-based filtering JRS.We propose both targeted attack method that makes some target journals appear more often in the system and non-targeted attack method that makes the system provide incorrect recommendations.We also conduct extensive experiments to validate the proposed methods.We hope this paper could help improve JRS by realizing the existence of such adversarial attacks. | Zhaoquan Gu Yinyin Cai Sheng Wang Mohan Li Jing Qiu Shen Su Xiaojiang Du Zhihong Tian | 2020 | Computers, Materials & Continua2020，，9： | 2 |
| 6 | Thermal transport by electrons and ions in warm dense aluminum:A combined density functional theory and deep potential study显示文摘We propose an efficient scheme that combines density functional theory(DFT)with deep potentials(DPs),to systematically study convergence issues in the computation of the electronic thermal conductivity of warm dense aluminum(2.7 g/cm^(3)and temperatures ranging from 0.5 eV to 5.0 eV)with respect to the number of k-points,the number of atoms,the broadening parameter,the exchange-correlation functionals,and the pseudopotentials.Furthermore,we obtain the ionic thermal conductivity using the Green–Kubo method in conjunction with DP molecular dynamics simulations,and we study size effects on the ionic thermal conductivity.This work demonstrates that the proposed method is efficient in evaluating both electronic and ionic thermal conductivities of materials. | Qianrui Liu Junyi Li Mohan Chen | 2021 | Matter and Radiation at Extremes2021，6，2： | 2 |
| 7 | Less is More:Ebola Surface GlycoproteinExpression Levels Regulate Virus Production and Infectivity显示文摘 | Mohan CS Ye L Li IW | 2014 | Jour-nal of virology2014，89，2： | 1 |
| 8 | Research Progress on Effects of Stocking Density on Performance, Health and Welfare of Duck显示文摘Stocking density is an important factor for animal production performance.It appears particularly urgent and important to research systematically on stocking density for the dual restriction of environmental protection and animal welfare.This review dealt with the influence of stocking density on ducks'productivity and health through production performance,animal behavior and animal welfare,and analyzed the possible mechanism of high stocking density reducing production performance,resulting in abnormal behavior and stress,causing welfare and health problems.We consider that it might be associated with heat stress,more spatial competition(to gather the food,drinking water,sports area,etc.),as well as the quality deterioration of litter and house air caused by high stocking density.Finally,we put forward some suggestions on the study of stocking density's effects on ducks,and proposed the future work that need to be studied and problems that need to be solved imminently. | Chaowu YANG Chunlin YU Zengrong ZHANG Mohan QIU Huarui DU Qingyun LI Xiaosong JIANG Xia XIONG | 2020 | Agricultural Biotechnology2020，9，4： | 1 |
| 9 | Hepatocyte growth factor and hepatocyte growth factor receptor in the lacrimal gland,tears,and cornea显示文摘 | Li Q Weng J Mohan R R | 1996 | Invest Ophthalmol Vis Sci1996，37，5： | 1 |
| 10 | IL-1 upregulates kerattnocyte growth factor and hepatocyte growth factor mRNA and protein production by cultured stromal fibroblast cells: interleukin-1 beta expression in the cornea显示文摘 | Weng J Mohan RR Li Q Wilson SE | 1997 | Cornea1997，16，4： | 1 |
| 11 | Differential protein profile in the ear-punched tissue of regeneration and non-regeneration strains of mice: a novel approach to explore the candidate genes for soft-tlssue regeneration 显示文摘 | Li X Mohan S Gu W etal | 2000 | Biochimiea et Biophysia Acta2000，1524，： | 1 |
| 12 | Exon array profiling detects EML4-ALK fusion in breast colorectal, and non-small cell lung cancers显示文摘 | Lin E Li L Guan Y Soriano R Rivers C S Mohan S | 2009 | Mol Cancer Res2009，7，： | 1 |
| 13 | Association between CpG island methylation and microsatellite instability in colorectal cancer显示文摘 | Ahuja N Mohan AL Li Q | 1997 | Cancer Res1997，57，16： | 1 |
| 14 | Genetic and Breeding Progress Analysis on Five Pure Lines of Dahen Broiler显示文摘To timely modify breeding scheme and improve selection efficiency of Dahen broiler,genetic and breeding progress analysis on five pure lines was conducted. The results showed that the selection on breeding goal traits of each line was effective since 14 generations,especially the selection on growth traits did not cause adverse influence on reproductive performance. After the 6 thgeneration,main performances of each line maintained in higher level,but the breeding progress obviously declined. It illustrated that current breeding means was effective for maintaining and consolidating breeding goal traits of Dahen broiler,and it should timely adjust breeding scheme to obtain more genetic progress. | Chaowu YANG Huarui DU Zengrong ZHANG Mohan QIU Chunlin YU Lan LIU Xiaoyu JIANG Bo XIA Chenming HU Xiaoyan SONG Xia XIONG Li YANG Han PENG Qingyun LI Xiaosong JIANG | 2018 | Agricultural Biotechnology2018，7，5： | 1 |
| 15 | Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus 显示文摘 | Mohan G S Li W Ye L | 2012 | PLoS Pathog2012，8，10： | 1 |
| 16 | Adapting multimedia intemet content for universal access显示文摘 | MOHAN R SMITH J R LI C S | 1999 | IEEE Transactions Multimedia1999，1，1： | 1 |
| 17 | Aging and DNA methylation in colorectal mucosa and cancer显示文摘 | Ahuja N Li Q Mohan AL | 1998 | Cancer Res1998，58，： | 1 |
| 18 | Differential protein profile in the ear-punched tissue of regeneration and non-regeneration strains of mice: a novel approach to explore the candidate genes for soft-tissue regeneration显示文摘 | Mohan S Gu W | 2000 | Biochimica et Biophysia Acta2000，1524，： | 1 |
| 19 | Aging and DNA methylation in colorectal mucosa and cancer显示文摘 | Ahuja N Li Q Mohan A L | 1998 | Caner Res1998，58，： | 1 |
| 20 | Hepatocyte growth factor,keratinocyte growth factor,and other growth factor-receptor systems in the lens显示文摘 | Weng J Liang Q Mohan RR Li Q Wilson SE | 1997 | Invest Ophthalmol Vis Sci1997，38，8： | 1 |
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