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| 1 | 化学气体污染突发事件中的人群疏散:横断面调查显示文摘目的比较一个塑料工厂发生化学事故后躲藏和被疏散人群的健康结局。设计横断面调查。背景英格兰西南的市区。研究对象该地区1750位曾暴露于化学烟雾的居民,其中472人被疏散,剩下的1278人被建议躲藏在室内。主要结局测定不利于健康的症状数目。出现4个或以上症状者被确定为一个病例。主要的结果1096位居民(63%;299人被疏散,797人躲藏起来)为本分析提供了资料。被疏散人群的平均症状分值和病例的比例比躲藏人群的要高(疏散者:症状分值1.9,病例比例19.7%(n=59);躲藏者:症状分值1.0,病例比例9.5%(n=76),二者比较P<0.001)。在事故发生后两周末时二组间的差异明显变小。成为病例的两个主要可变更危险因子是疏散(比值比2.5,95%可信区间1.7~3.8)和在事故当天直接暴露于烟雾的时间超过2小时(比值比2.0,95%可信区间1.7~2.3)。住所距工厂的距离或是干预前(头6个小时)暴露的水平对于研究对象成为病例的作用不大。结论在此次化学事故中躲藏起来可能是优于疏散人群的保护措施。这与专家们普遍认为的观点一致。尽管本研究有一定的局限性,但它是基于一场真实的事件。疏散本身有一定的风险和资源上的限制,认识上的增加可能会有助于减少将来不必要的疏散。 | S Kinra G Lewendon R Nelder N Herriott R Mohan M Hort S Harrison V Murray 陈雷(译) | 2005 | 英国医学杂志中文版2005，8，5： | 3 |
| 2 | Toll-like receptor expression and signaling in human diabetic wounds显示文摘AIM: To examine the contribution of toll-like receptors(TLRs) expression and activation to the prolonged inflammation often seen in human diabetic wounds.METHODS: Debridement wound tissue was collected from diabetic patients with informed consent. Total RNA and protein were isolated and subjected to real-time polymerase chain reaction and Western blot analyses. RESULTS: TLR1, 2, 4, and 6 mRNA expressions were increased significantly in wounds of diabetic patients compared with non-diabetic wounds(P < 0.05). MyD88 protein expression was significantly increased in diabetic wounds compared to non-diabetic wounds. Interleukin-1beta, tumor necrosis factor-alpha concentration nuclear factor-kappa B activation, and thiobarbituric acid reactive substances were increased in diabetic wounds compared to non-diabetic wounds(P < 0.01). CONCLUSION: Collectively, our novel findings show that increased TLR expression, signaling, and activation may contribute to the hyper inflammation in the human diabetic wounds. | Mohan R Dasu Sandra J Martin | 2014 | World Journal of Diabetes2014，5，2： | 2 |
| 3 | Advances in genetically engineered(transgenic) plants in pest management-an over view显示文摘 | Mohan Babu R Sajeena A Seetharaman K | 2003 | Crop Protection2003，22，： | 2 |
| 4 | Matrix metalloproteinase gelatinase B (MMP-9) coordinates and effects epithelial regeneration显示文摘 | Mohan R Chintala SK Jung JC | 2002 | J Biol Chem2002，277，： | 2 |
| 5 | Application of fast simulated annealing to optimization of eonformal radiation treatments 显示文摘 | Mageras GS Mohan R | 1993 | Med Phys1993，20，3： | 1 |
| 6 | Active input-voltage and load-current sharing in input-series and output- parallel connected modular DC-DC converters using dynamic input-voltage reference scheme 显示文摘 | Ayyanar R Giri R Mohan N | 2004 | IEEE Trans Power Electron2004，19，： | 1 |
| 7 | Apoptosis, necrosis, pro- liferation, and myofibroblast generation in the stroma following LASIK and PRK显示文摘 | Mohan RR Huteheon AE Choi R | 2003 | Exp Eye Res2003，76，1： | 1 |
| 8 | Effects of cadmium salt on phosphomonoesterases activity and fertilizing ability of fowl spermatozoa显示文摘 | Mohan J Moudgal R P Panda J N | 1992 | Indian J Experi Biol1992，30，： | 1 |
| 9 | Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy 显示文摘 | Netto MV Mohan RR Ambrosio R Jr | 2005 | Cornea2005，24，5： | 1 |
| 10 | The Gotfried percutaneous compression plate compared with the conventional classic hip screw for the fixation of intertrochanteric fractures of the hip显示文摘 | Kosygan KP Mohan R Newman RJ | 2002 | J Bone Joint Surg Br2002，84，1： | 1 |
| 11 | MicroRNAs as pharma- cological targets in diabetes 显示文摘 | Mao Y Mohan R Zhang S | 2013 | Pharmacol Res2013，75，1： | 1 |
| 12 | Preparation andpartial characterization of collagen sheet from fish scales 显示文摘 | SANKAR S SEKAR S MOHAN R | 2008 | International Journal of Biological Macromolecules2008，42，1： | 1 |
| 13 | Biofiber-reinforced polypropylene composites 显示文摘 | Karnani R Mohan K Ramini N | 1997 | Polymer Engineering and Science1997，37，： | 1 |
| 14 | Bioremediation of anthracene contaminated soil in bio-slurry phase reactor operated in periodic discontinuous batch mode显示文摘 | PRASANNA D VENKATA Mohan S PURUSHOTHAM R B | 2008 | Journal of Hazardous Materials2008，，153： | 1 |
| 15 | Estimation of selum zinc and copper in children with acute diarrhea显示文摘 | Aroa R Kulshreshtha S Mohan G | 2006 | Biol Trace Elem Res2006，11，4： | 1 |
| 16 | Acaching strategy to reduce network impacts of PCS显示文摘 | Jain R Lin Y B Mohan S | 1994 | IEEE Journal on Seleetecl Areas in Communications1994，12，8： | 1 |
| 17 | Stereophonic acoustic echo cancellation-an overview of the fundamental problem显示文摘 | M Mohan Sondhi Dennis R Morgan Joseph L Hall | 1995 | IEEE Signal Processing Letters1995，2，8： | 1 |
| 18 | Apoptosis, necrosis, proliferation, and myofibroblast generation in the stroma following LASIK and PRK显示文摘 | Mohan RR Hutcheon AE Choi R Hong J Lee J Mohan RR | 2003 | Exp Eye Res2003，76，： | 1 |
| 19 | On a Pure Finite-Element-Based Methodology for Resin Transfer Mold Filling Simulation显示文摘 | Mohan R V Ngo N D Tamma K K | 1999 | Polymer Engineering and Science1999，39，1： | 1 |
| 20 | Validity of concept of separating primary and scatter dose显示文摘 | MOHAN R CHUI C | 1985 | Med Phys1985，12，6： | 1 |
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