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| 1 | A Survey of Unbalanced Flow Diagnostics and Their Application显示文摘This paper presents an extensive survey of the most commonly used tools for diagnosing unbalanced flow in the atmosphere, namely the Lagrangian Rossby number, Psi vector, divergence equation, nonlinear balance equation, generalized omega-equation, and departure from fields obtained by potential vorticity (PV) inversion. The basic thoery, assumptions as well as implementation and limitations for each of the tools are all discussed. These tools are applied to high-resolution mesoscale model data to assess the role of unbalanced dynamics in the generation of a mesoscale gravity wave event over the East Coast of the United States. Comparison of these tools in this case study shows that these various methods agree to a large extent with each other though they differ in details. | Fuqing Zhang Steven E. Koch Christopher A. Davis and Michael L. Kaplan | 2000 | Advances in Atmospheric Sciences2000,17,2: | 22 |
| 2 | Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease显示文摘AIM To determine if manipulation of dietary advanced glycation end product(AGE), intake affects nonalcoholic fatty liver disease(NAFLD) progression and whether these effects are mediated via RAGE. METHODS Male C57Bl6 mice were fed a high fat, high fructose, high cholesterol(HFHC) diet for 33 wk and compared with animals on normal chow. A third group were given a HFHC diet that was high in AGEs. Another group was given a HFHC diet that was marinated in vinegar to prevent the formation of AGEs. In a second experiment, RAGE KO animals were fed a HFHC diet or a high AGE HFHC diet and compared with wildtype controls. Hepatic biochemistry, histology, picrosirius red morphometry and hepatic mR NA were determined. RESULTS Long-term consumption of the HFHC diet generated significant steatohepatitis and fibrosis after 33 wk. In this model, hepatic 4-hydroxynonenal content(a marker of chronic oxidative stress), hepatocyte ballooning, picrosirius red staining, α-smooth muscle actin and collagen type 1A gene expression were all significantly increased. Increasing the AGE content of the HFHC diet by baking further increased these markers of liver damage, but this was abrogated by pre-marination in acetic acid. In response to the HFHC diet, RAGE-/-animals developed NASH of similar severity to RAGE+/+ animals but were protected from the additional harmful effects of the high AGE containing diet. Studies in isolated Kupffer cells showed that AGEs increase cell proliferation and oxidative stress, providing a likely mechanism through which these compounds contribute to liver injury. CONCLUSION In the HFHC model of NAFLD, manipulation of dietary AGEs modulates liver injury, inflammation, and liver fibrosis via a RAGE dependent pathway. This suggests that pharmacological and dietary strategies targeting the AGE/RAGE pathway could slow the progression of NAFLD. | Christopher Leung Chandana B Herath Zhiyuan Jia Sof Andrikopoulos Bronwyn E Brown Michael J Davies Leni R Rivera John B Furness Josephine M Forbes Peter W Angus | 2016 | World Journal of Gastroenterology2016,22,35: | 7 |
| 3 | Metal concentrations of insects associated with the South African Ni hyperaccumulator Berkheya coddii (Asteraceae)显示文摘在亢奋的蓄电池种的金属的一些金属的高水平可以被转移到昆虫伙伴。我们调查了从南非的 Nihyperaccumulator Berkheya coddii 收集记录整个身体的金属集中的昆虫(公司, Cr, Cu, Mg, Mn, Ni, Pb, Zn ) 。我们也在叶子,茎和开花期记录了这些金属的集中,发现 Ni 的层次极其提高了(4 700—16 000 亩 g/g ) 并且高价值(5—34 亩 g/g ) 为公司, Cr,和 Pb。从 B 镇定的 26 昆虫 morphotypes。coddii,七 heteropterans,一只甲虫类之昆虫,和一只直翅类的昆虫包含了 Ni 的相对高的集中(>
500 亩 g/g ) 。high-Ni heteropterans 的 Thelarge 数字增加其它的发现(从加利福尼亚美国和新喀里多尼亚) 并且建议这份昆虫订单的成员可以是特别地 Ni 容忍。直翅类的昆虫(Stenoscepa ) 的美女包含了 3 500 亩 g Ni/g,最大的 Ni 集中还为一只昆虫报导了。我们也与 Mg 的提高的层次发现了二甲壳虫(>
2 800 亩 g/g ) ,有提高的 Cu 的一甲壳虫(>
70 亩 g/g ) 并且有 Mn 的提高的水平的一 heteropteran (>
200 亩 g/g ) 。在一个 Ni 亢奋的蓄电池上喂的昆虫能动员的 Ourresults 表演 Ni 进食物网,尽管我们没在草食动物或食肉动物昆虫发现 Ni 简历放大的证据,征税一。我们也断定与亢奋的蓄电池联系的一些昆虫能包含足够高对脊椎动物有毒的 Ni 层次。 | ROBERT S. BOYD MICHEAL A. DAVIS MICHAEL A. WALL KEVIN BALKWILL | 2006 | Insect Science2006,13,2: | 5 |
| 4 | miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting显示文摘 | Christine Esau Scott Davis Susan F. Murray Xing Xian Yu Sanjay K. Pandey Michael Pear Lynnetta Watts Sheri L. Booten Mark Graham Robert McKay Amuthakannan Subramaniam Stephanie Propp Bridget A. Lollo Susan Freier C. Frank Bennett Sanjay Bhanot Brett P. Mo | 2006 | Cell Metabolism2006,,2: | 4 |
| 5 | Assessing the impact of natural enemies in agroecosystems: toward "real" IPM or in quest of the Holy Grail?显示文摘 | Myron P. Zalucki Michael J. Furlong Nancy A. Schellhorn Sarina Macfadyen Andrew P. Davies | 2015 | Insect Science2015,22,1: | 4 |
| 6 | Host-herbivore studies of Stenoscepa sp. (Orthoptera:Pyrgomorphidae), a high-Ni herbivore of the South African Ni hyperaccumulator Berkheya coddii (Asteraceae)显示文摘Stenoscepa sp 的美女。在在在 Mpumalanga 省的蛇的地点的 Ni 亢奋的蓄电池 Berkheyacoddii 的叶子的 feed,南非。这些地点在正常范围与 Ni 集中包含 Nihyperaccumulators, Ni 蓄电池,和植物。Weconducted 学习到:(ⅰ) 决定美女的整个身体的金属集中(包括那些饥饿倒空他们的勇气) ;(ⅱ) 比较 Stenoscepa sp。对在为整个身体的金属集中的一样的产地的另外的蚂蚱的美女;并且(ⅲ) 当食物为 Stenoscepa sp 采购原料,比较 Nihyperaccumulator 和 Ni 蓄电池植物的适用性。并且另外的蚂蚱。Stenoscepa 美女有极其高整个身体的 Ni 集中(3 500 μ g Ni/g ) 。这是部分由于在内脏的食物使少些包含的昆虫饿了 .Stenoscepa 美女比另外的蚂蚱更好显著地熬过的 Ni (950 μ g Ni/g ) 从也收集了一 serpentine 或一个非蛇的地点当作为食物提供了 high-Ni 植物时。在在四 Berkheya 种(二个 Ni 亢奋的累加器和二个 Ni 累加器) 之中的主机偏爱测试, Stenoscepa sp.preferred Ni 亢奋的累加器种类离开。使用的一个偏爱实验 threeSenecio 种类离开(哪个种类, Senecio coronatus,被 Nihyperaccumulator 和一张 Ni 蓄电池人口代表) 显示出那 Stenoscepa sp。比较喜欢的 Niaccumulator Senecio coronatus 离开到所有另外的选择。我们结束那 Stenoscepa sp。是极其 Ni 容忍的。Stenoscepa sp。美女比较喜欢亢奋的蓄电池 Berkheya 种类的叶子,但是提高的 Ni 集中独自不决定他们的食物偏爱。我们建议 Stenoscepa 美女的极其高整个身体的 Ni 集中可以在这些蛇的社区影响食物网关系。 | ROBERT S. BOYD MICHEAL A. DAVIS MICHAEL A. WALL KEVIN BALKWILL | 2007 | Insect Science2007,14,2: | 4 |
| 7 | 经下腔静脉途径拔除起搏导线的初步体会显示文摘目的 介绍应用血管内反推力技术经下腔静脉途径拔除起搏导线的初步临床体会。 方法 对 1 8例患者的 2 8根导线应用血管内反推力牵引技术拔除导线 ,其中 1 6例 (2 5根导线 )首选经上腔静脉途径 ,失败后改用经下腔静脉途径 ;2例 (3根导线 )直接用经下腔静脉途径拔除。 结果 1 6例患者的 2 5根导线 ,经上腔静脉途径完全拔除 2 2根 (88% ) ,3根经此途径拔除失败后改用下腔静脉途径 ,其中 2根完全拔除。 2例患者的 3根导线直接选用经下腔静脉途径完全拔除。因此 ,本组患者经上下腔静脉两种途径分别拔除导线 2 2根及 5根 ,成功率为 96 .4% (2 7/ 2 8)。两种途径拔除均失败的 1根心室电极导线经开胸手术顺利取出。本组患者术中及术后无严重并发症。 结论 经下腔静脉途径拔除起搏导线可用于经上腔静脉途径拔除失败者 ,亦可直接选用。 | 杨杰孚 Anne Powell Michael Davi | 2000 | 中华心律失常学杂志2000,4,1: | 3 |
| 8 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013,,9883: | 3 |
| 9 | Cell:癌基因“遗传平衡”或会影响患者对癌症疗法的反应显示文摘进行癌症疗法的选择越来越需要确定肿瘤细胞中是否含有一些特殊突变的癌基因会驱动癌细胞异常生长。并且确定是否癌细胞会对特殊药物耐受或敏感.近日来自加州大学旧金山分校的研究人员就通过研究发现。以常见的癌基因KRAs突变为例。患者对疗法的反应往往会随着肿瘤的不断进化而发生改变。相关研究刊登于国际杂志Cell上。 | Michael R. Burgess Eugene Hwang Rana Mroue Craig M. Bielski Anica M. Wandler Benjamin J. Huang Ari J. Firestone Amy Young Jennifer A. Lacap Lisa Crocker Saurabh Asthana Elizabeth M. Davis Jin Xu Keiko Akagi Michelle M. Le Beau Qing Li Benjamin Haley David Stokoe Deepak Sampath Barry S. Taylor Marie Evangelista Kevin Shannon | 2017 | 现代生物医学进展2017,17,18: | 2 |
| 10 | 静脉注射索他洛尔对程序刺激诱发性室性心动过速的抑制作用及其电生理效应显示文摘 | 杨杰孚 Anne Powell Michael Davis | 1999 | 中华心血管病杂志1999,27,4: | 2 |
| 11 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010,,12: | 2 |
| 12 | Nutritional therapy in patients with acute pancreatitis requiring critical care unit management: A prospective observational study in Australia and New Zealand显示文摘 | Andrew R. Davies Siouxzy S. Morrison Emma J. Ridley Michael Bailey Merrilyn D. Banks David J. Cooper Gil Hardy Kerry McIlroy Andrew Thomson | 2011 | Critical Care Medicine2011,,3: | 2 |
| 13 | Changes in manganese and lead in the environment and young children associated with the introduction of MMT in gasoline显示文摘 | Brian Gulson Karen Mizon Michael Korsch Honway Louie Michael Wu Jenny Stauber J. Michael Davis Alan Taylor | 2006 | Chinese Journal Of Geochemistry2006,25,B08: | 2 |
| 14 | 经股静脉放置冠状静脉窦导管的临床体会显示文摘报道 2 2 1例因反复发作室上性心动过速行射频消融术的患者 ,使用顶端弯度可调控导管经股静脉径路送入冠状静脉窦标测电极的临床体会。 2 2 1例患者中 ,成功地经股静脉途径放置冠状静脉窦电极 2 0 0例 (90 .5 % )。其中房室结双径路者的放置成功率为 98% ,房室旁道为 81.5 % ,房性心动过速及心房扑动为 93.3%。 2 1例失败者穿刺左锁骨下静脉 ,19例经该静脉成功地送入冠状静脉窦电极 ,2例失败。所有病人无与放置冠状静脉窦导管有关的并发症。因而 ,使用顶端弯度可调控的导管经股静脉途径放置冠状静脉窦电极效果良好 ,尤其在房室结双径路的患者。此方法安全 ,避免了穿刺锁骨下静脉以及由此引起的并发症。 | 杨杰孚 佟佳宾 吴军 刘焕明 杨羽 李梅 吴素鹃 王志蕾 Anne Powell Michael Davis | 2000 | 中国心脏起搏与心电生理杂志2000,14,1: | 2 |
| 15 | Endoscopic Management of Postcholecystectomy Bile Duct Strictures显示文摘 | Gary C. Vitale Tin C. Tran Brian R. Davis Michael Vitale David Vitale Gerald Larson | 2008 | Journal of the American College of Surgeons2008,,5: | 2 |
| 16 | Systems Integration:A Core Capability of the Modem Corporation显示文摘 | Hobday Michael Andrew Davies and Andrea Prencipe | 2005 | Industrial and Corporate Change2005,,14: | 1 |
| 17 | ' 显示文摘 | Davies James and Michael Hoy ' Flat Rate Taxes and Inequality Measurement | 2002 | Journal of Public Economics2002,84,: | 1 |
| 18 | Smart manufacturing,manufacturing intelligence and demand-dynamic performance显示文摘 | Jim Davis Thomas Edgar James Porter John Bernaden Michael Sarlie | | 0,,12: | 1 |
| 19 | Integration of rock physics,reservoir simulation,and time-lapse seismic data for reservoir characterization at Weyburn Field, Saskatchewan 显示文摘 | Davis T L Batzle Michael | 2002 | Expanded Abstracts of 72nd Annual Internat SEG Mtg2002,,: | 1 |
| 20 | Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells显示文摘 | Joanne N Davis Michael T Mc Cabe | 2005 | Cancer Res2005,65,9: | 1 |