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| 1 | Towards 10 Gb/s orthogonal frequency division multiplexing-based visible light communication using a GaN violet micro-LED显示文摘Visible light communication(VLC)is a promising solution to the increasing demands for wireless connectivity.Gallium nitride micro-sized light emitting diodes(micro-LEDs)are strong candidates for VLC due to their high bandwidths.Segmented violet micro-LEDs are reported in this work with electrical-to-optical bandwidths up to 655 MHz.An orthogonal frequency division multiplexing-based VLC system with adaptive bit and energy loading is demonstrated,and a data transmission rate of 11.95 Gb/s is achieved with a violet micro-LED,when the nonlinear distortion of the micro-LED is the dominant noise source of the VLC system.A record 7.91 Gb/s data transmission rate is reported below the forward error correction threshold using a single pixel of the segmented array when all the noise sources of the VLC system are present. | MOHAMED SUFYAN ISLIM RICARDO X.FERREIRA XIANGYU HE ENYUAN XIE STEFAN VIDEV SHAUN VIOLA SCOTT WATSON NIKOLAOS BAMIEDAKIS RICHARD V.PENTY IAN H.WHITE ANTHONY E.KELLY ERDAN GU HARALD HAAS MARTIN D.DAWSON | 2017 | Photonics Research2017，5，2： | 23 |
| 2 | An epigenomic approach to therapy for tamoxifen-resistant breast cancer显示文摘Tamoxifen 是为雌激素受体 alpha 的前线治疗(ERα) 在绝经前的女人的积极的胸肿瘤。然而,到 tamoxifen 的抵抗发生在许多病人。嗯仍然与获得的 tamoxifen 抵抗在乳癌房间的生长起一个关键作用,建议那 ERα为治疗仍然是一个有效目标 tamoxifen 抵抗(Tam-R ) 乳癌。以识别 ERα 的新奇管理者;发信号,通过对 histone 甲基修饰词的一幅小规模的 siRNA 屏幕,我们发现了 WHSC1, histone H3K36 methyltransferase, ERα 的一个积极管理者;在乳癌房间发信号。我们证明 WHSC1 被招募到 ERα由 BET 蛋白质 BRD3/4 的基因,并且便于 ERα基因表示。小分子的赌注蛋白质禁止者 JQ1 potently 压制了经典 ERα发信号的小径和在文化的 Tam-R 乳癌房间的生长。用一个 Tam-R 乳癌异种皮移植老鼠模型,我们与 JQ1 和 ER degrader fulvestrant 由 JQ1 和联合治疗的强壮的长持续的效果在 vivo 反胸癌症活动示威了。一起拿,我们提供 epigenomic 蛋白质 BRD3/4 和 WHSC1 是雌激素受体发信号的必要管理者并且是为 Tam-R 乳癌的治疗的新奇治疗学的目标的证据。 | Qin Feng Zheng Zhang Martin J Shea Chad J Creighton Cristian Coarfa Susan G Hilsenbeck Rainer Lanz Bin He Lei Wang Xiaoyong Fu Agostina Nardone Yongcheng Song James Bradner Nicholas Mitsiades Constantine S Mitsiades C Kent Osborne Rachel Schiff Bert W O'Malley | 2014 | Cell Research2014，24，7： | 10 |
| 3 | 1 Gbps free-space deep-ultraviolet communications based on Ⅲ-nitride micro-LEDs emitting at 262 nm显示文摘The low modulation bandwidth of deep-ultraviolet(UV) light sources is considered as the main reason limiting the data transmission rate of deep-UV communications. Here, we present high-bandwidth Ⅲ-nitride microlight-emitting diodes(μLEDs) emitting in the UV-C region and their applications in deep-UV communication systems. The fabricated UV-C μLEDs with 566 μm2 emission area produce an optical power of 196 μW at the 3400 A∕cm2 current density. The measured 3 dB modulation bandwidth of these μLEDs initially increases linearly with the driving current density and then saturates as 438 MHz at a current density of 71 A∕cm2, which is limited by the cutoff frequency of the commercial avalanche photodiode used for the measurement. A deep-UV communication system is further demonstrated. By using the UV-C μLED, up to 800 Mbps and 1.1 Gbps data transmission rates at bit error ratio of 3.8 × 10-3 are achieved assuming on-off keying and orthogonal frequency-division multiplexing modulation schemes, respectively. | Xiangyu He Enyuan Xie Mohamed Sufyan Islim Ardimas Andi Purwita Jonathan J.D.McKendry Erdan Gu Harald Haas Martin D.Dawson | 2019 | Photonics Research2019，7，7： | 9 |
| 4 | Discrete particle modeling of granular temperature distribution in a bubbling fluidized bed显示文摘The discrete hard sphere particle model (DPM) is applied in this work to study numerically the distributions of particle and bubble granular temperatures in a bubbling fluidized bed. The dimensions of the bed and other parameters are set to correspond to those of Müller et al. (2008). Various drag models and operational parameters are investigated to find their influence on particle and bubble granular temperatures. Various inlet superficial gas velocities are used in this work to obtain their effect on flow characteristics. It is found that the superficial gas velocity has the most important effect on granular temperatures including bubble granular temperature, particle translational granular temperature and particle rotational granular temperature. The drag force model affects more seriously the large scale variables such as the bubble granular temperature. Restitution coefficient influences all granular temperatures to some degree. Simulation results are compared with experimental results by Müller et al. (2008) showing reasonable agreement. | Yurong He Tianyu Wang Niels Deen Martin van Sint Annaland Hans Kuipers Dongsheng Wen | 2012 | Particuology2012，10，4： | 4 |
| 5 | New Early Cretaceous Pterosaur-Bird Track Assemblage from Xinjiang, China:Palaeoethology and Palaeoenvironment显示文摘A pterosaur-bird track assemblage from a sandstone-siltstone-mudstone sequence of the Lower Cretaceous Tugulu Group of Xinjiang comprises the first pterosaur track record from this province and the largest specimen thus far known from China.The pterosaur tracks are assigned to the ichnogenus Pteraichnus based on the triangular overall-shape,the four elongate digit traces and the robust manual digit trace III.Supposed trackmakers were dsungaripterid pterodactyloids whose skeletal remains are well known from the Tugulu Group.The bird tracks that occur on the same surface,are those of typical shorebirds,known from different other localities in southeast Asia.The congruence with Koreanaornis dodsoni described from the same stratigraphic level justifies an assignment to this ichnospecies.This is a further evidence of the co-occurrence of pterosaurs and birds in a typical lakeshore environment with possible seasonal alteration of water supply and aerial exposure indicated by wave ripples,mudcracks and repeated cycles of coarse to fine sediment.Pterosaurs and birds frequented the shoreline and may have fed also on the numerous invertebrates such as the Scoyenia tracemaker that left abundant burrows. | HE Qing XING Lida ZHANG Jianping Martin G.LOCKLEY Hendrik KLEIN W.Scott PERSONS IV QI Liqi JIA Chengkai | 2013 | Acta Geologica Sinica(English Edition)2013，87，6： | 4 |
| 6 | Polarisation optics for biomedical and clinical applications:a review显示文摘Many polarisation techniques have been harnessed for decades in biological and clinical research,each based upon measurement of the vectorial properties of light or the vectorial transformations imposed on light by objects.Various advanced vector measurement/sensing techniques,physical interpretation methods,and approaches to analyse biomedically relevant information have been developed and harnessed.In this review,we focus mainly on summarising methodologies and applications related to tissue polarimetry,with an emphasis on the adoption of the Stokes-Mueller formalism.Several recent breakthroughs,development trends,and potential multimodal uses in conjunction with other techniques are also presented.The primary goal of the review is to give the reader a general overview in the use of vectorial information that can be obtained by polarisation optics for applications in biomedical and clinical research. | Chao He Honghui He Jintao Chang Binguo Chen Hui Ma Martin J.Booth | 2021 | Light(Science & Applications)2021，10，11： | 4 |
| 7 | Executive compensation and corporate governance in China显示文摘 | Martin J. Conyon Lerong He | 2011 | Journal of Corporate Finance2011，，4： | 4 |
| 8 | Investigation on aerodynamic force effect of vacuum plumes using pressure-sensitive paint technique and CFD-DSMC solution显示文摘Pressure-sensitive paint(PSP) technique was employed to experimentally investigate the aerodynamic force effect of vacuum plume in this study. The characterization and comparison for two types of PSP were firstly conducted in an air pressure range from0.05 to 5000 Pa. The PSPs were prepared using PtTFPP as the active dye and different binders, i.e., polymer-ceramic(PC) and poly(1-trimethylsilyl-1-propyne) [poly(TMSP)]. The static calibrations showed that PtTFPP/poly(TMSP) had a higher pressure sensitivity and a lower temperature dependency compared to PtTFPP/PC in this pressure range. The pressure distributions of a single and two interacting plumes impinging onto a flat plate model were measured using PSP technique. The experimental data were compared to numerical solutions that combined both the computed fluid dynamics(CFD) and direct simulation Monte Carlo(DSMC) methods. Remarkable agreements were achieved, demonstrating the feasibility and accuracy of the numerical approach.Finally, the aerodynamic force effect of interacting plumes at different separation distances was investigated numerically. | WU Jing BITTER Martin CAI GuoBiao HE BiJiao KAEHLER Christian | 2017 | Science China(Technological Sciences)2017，60，7： | 3 |
| 9 | A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration显示文摘The osteogenic microenvironment of bone-repairing materials plays a key role in accelerating bone regeneration but remains incompletely defined,which significantly limits the application of such bioactive materials.Here,the transcriptional landscapes of different osteogenic microenvironments,including three-dimensional(3D)hydroxyapatite(HA)scaffolds and osteogenic medium(OM),for mesenchymal stromal cells(MSCs)in vitro were mapped at single-cell resolution.Our findings suggested that an osteogenic process reminiscent of endochondral ossification occurred in HA scaffolds through sequential activation of osteogenic-related signaling pathways,along with inflammation and angiogenesis,but inhibition of adipogenesis and fibrosis.Moreover,we revealed the mechanism during OM-mediated osteogenesis involves the ZBTB16 and WNT signaling pathways.Heterogeneity of MSCs was also demonstrated.In vitro ossification of LRRC75A+MSCs was shown to have better utilization of WNT-related ossification process,and PCDH10+MSCs with superiority in hydroxyapatite-related osteogenic process.These findings provided further understanding of the cellular activity modulated by OM conditions and HA scaffolds,providing new insights for the improvement of osteogenic biomaterials.This atlas provides a blueprint for research on MSC heterogeneity and the osteogenic microenvironment of HA scaffolds and a database reference for the application of bioactive materials for bone regeneration. | Peng Guo Xizhe Liu Penghui Zhang Zhongyuan He Zhen Li Mauro Alini RGeoff Richards Sibylle Grad Martin J.Stoddart Guangqian Zhou Xuenong Zou Danny Chan Wei Tian Dafu Chen Manman Gao Zhiyu Zhou Shaoyu Liu | 2022 | Bioactive Materials2022，7，3： | 3 |
| 10 | Octavinyl polyhedral oligomeric silsesquioxane on tailoring the DC electrical characteristics of polypropylene显示文摘This work reports the effect of octavinyl polyhedral oligomeric silsesquioxane(OvPOSS)on tuning the electrical performance of polypropylene(PP).OvPOSS with different content are introduced into PP using the solution method.The microstructural morphology,crystallinity behaviour,breakdown strength,DC conductivity,space charge formation,and trapping level distribution are measured.The results indicate that the OvPOSS nanofiller can be dispersed uniformly with a doping content of 2.0 phr or less.The DC conductivity is decreased,and the breakdown strength of OvPOSS/PP nano-composites is significantly increased.The space charge accumulation of the OvPOSS/PP nanocomposites is significantly suppressed due to the introduction of deeper traps by the OvPOSS nanofiller.Finally,the experimental results demonstrate that the OvPOSS nanofiller can greatly increase the electrical performance of the base PP and the OvPOSS/PP nanocomposites have much potential for HVDC applications.They further demonstrate that the PP is environmental‐friendly due to its thermo‐plastic property,which can be recycled after the manufacture. | Xiaosi Lin Wah Hoon Siew John Liggat Martin Given Jinliang He | 2022 | High Voltage2022，7，1： | 2 |
| 11 | Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells显示文摘AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth.METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability was assessed in XTT assays. For analysis of cell cycle and cell death,flow cytometry and DAPI staining were applied. Expression of cyclooxygenase-2 (COX-2),p21 and bcl-2 in cells incubated with AA or DHA was examined by real-time RT-PCR. Prostaglandin E2 (PGE2) generation in the presence of AA and DHA was measured using a PGE2-ELISA.RESULTS:AA increased cell growth,whereas DHAreduced viability of LS 174T cells in a time-and dose-dependent manner. Furthermore,DHA down-regulated mRNA of bcl-2 and up-regulated p21. Interestingly,DHA was able to suppress AA-induced cell proliferation and significantly lowered AA-derived PGE2 formation. DHA also down-regulated COX-2 expression. In addition to the effect on PGE2 formation,DHA directly reduced PGE2-induced cell proliferation in a dose-dependent manner. CONCLUSION:These results suggest that DHA can inhibit the pro-proliferative effect of abundant AA or PGE2. | Piet Habbel Karsten H Weylandt Katja Lichopoj Johannes Nowak Martin Purschke Jing-Dong Wang Cheng-Wei He Daniel C Baumgart Jing X Kang | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 12 | Effect of different surface treatment agents on the physical chemistry and electrical properties of polyethylene nano-alumina nanocomposites显示文摘Generally,the electrical properties of nanocomposite are affected by the type,size,filling concentration and surface treatment process of the nanoparticle.In this study,nanocomposites of polyethylene(PE)with varying filling contents of nanoalumina particles were prepared by the melting blending method and three different kinds of coupling agents were applied for surface modification properties of the nanoparticles.Two of them were silane based and the other was titanate based.The effect of different coupling agents on the dielectric properties was studied.Fourier-transform infrared spectroscopy and thermo-gravimetric analysis were used to verify their compositions.Scanning electron microscope and polarised optical microscopy were used for morphology study.Dielectric permittivity,direct current(DC)volume resistivity and DC breakdown strength characterised their improved insulation performance with nano-alumina as filler.Thermal stimulated current results revealed that adding nano-alumina particles into low-density PE could provide more deep traps and increase DC resistivity. | Xuhui Duan Wah Hoon Siew Martin Given John Liggat Jinliang He | 2020 | High Voltage2020，5，4： | 2 |
| 13 | Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration显示文摘It has been proven that the mechanical microenvironment can impact the differentiation of mesenchymal stem cells(MSCs).However,the effect of mechanical stimuli in biofabricating hydroxyapatite scaffolds on the inflammatory response of MSCs remains unclear.This study aimed to investigate the effect of mechanical loading on the inflammatory response of MSCs seeded on scaffolds.Cyclic mechanical loading was applied to biofabricate the cell-scaffold composite for 15 min/day over 7,14,or 21 days.At the predetermined time points,culture supernatant was collected for inflammatory mediator detection,and gene expression was analyzed by qRT-PCR.The results showed that the expression of inflammatory mediators(IL1B and IL8)was downregulated(p<0.05)and the expression of ALP(p<0.01)and COL1A1(p<0.05)was upregulated under mechanical loading.The cell-scaffold composites biofabricated with or without mechanical loading were freeze-dried to prepare extracellular matrix-based scaffolds(ECM-based scaffolds).Murine macrophages were seeded on the ECM-based scaffolds to evaluate their polarization.The ECM-based scaffolds that were biofabricated with mechanical loading before freeze-drying enhanced the expression of M2 polarization-related biomarkers(Arginase 1 and Mrc1,p<0.05)of macrophages in vitro and increased bone volume/total volume ratio in vivo.Overall,these findings demonstrated that mechanical loading could dually modulate the inflammatory responses and osteogenic differentiation of MSCs.Besides,the ECM-based scaffolds that were biofabricated with mechanical loading before freeze-drying facilitated the M2 polarization of macrophages in vitro and bone regeneration in vivo.Mechanical loading may be a promising biofabrication strategy for bone biomaterials. | Penghui Zhang Xizhe Liu Peng Guo Xianlong Li Zhongyuan He Zhen Li Martin J.Stoddart Sibylle Grad Wei Tian Dafu Chen Xuenong Zou Zhiyu Zhou Shaoyu Liu | 2021 | Bioactive Materials2021，6，10： | 2 |
| 14 | Revealing complex optical phenomena through vectorial metrics显示文摘Advances in vectorial polarization-resolved imaging are bringing new capabilities to applications ranging from fundamental physics through to clinical diagnosis.Imaging polarimetry requires determination of the Mueller matrix(MM)at every point,providing a complete description of an object’s vectorial properties.Despite forming a comprehensive representation,the MM does not usually provide easily interpretable information about the object’s internal structure.Certain simpler vectorial metrics are derived from subsets of the MM elements.These metrics permit extraction of signatures that provide direct indicators of hidden optical properties of complex systems,while featuring an intriguing asymmetry about what information can or cannot be inferred via these metrics.We harness such characteristics to reveal the spin Hall effect of light,infer microscopic structure within laser-written photonic waveguides,and conduct rapid pathological diagnosis through analysis of healthy and cancerous tissue.This provides new insight for the broader usage of such asymmetric inferred vectorial information. | Chao He Jintao Chang Patrick S.Salter Yuanxing Shen Ben Dai Pengcheng Li Yihan Jin Samlan Chandran Thodik Mengmeng Li Aziz Tariq Jingyu Wang Jacopo Antonello Yang Dong Ji Qi Jianyu Lin Daniel S.Elson Min Zhang Honghui He Hui Ma Martin J.Booth | 2022 | Advanced Photonics2022，4，2： | 2 |
| 15 | Multiple viral re- spiratory pathogens in children with hronchiolitis显示文摘 | Stempel HE Martin ET Kuypers J | 2009 | Acts Pediatric2009，98，1： | 1 |
| 16 | Multiple viral respiratory pathogens in children with bronchiolitis 显示文摘 | Stempel HE Martin ET Kuypers J | 2009 | Acta Paediatr Jan2009，98，1： | 1 |
| 17 | Marine ecoregions of the world:a bioregionalization of coastal and shelf areas显示文摘 | Spalding MD Fox HE Allen GR Davidson N Ferdafia ZA Finlayson M Halpern BS Jorge MA Lombana AL Lourie SA Martin KD Manus EC Molnar J Recchia CA Robertson J | | 0，，： | 1 |
| 18 | Temperature and soil organic matter decomposition rates-synthesis of current knowledge and a way forward显示文摘 | Conant RT Ryan MG Agren GI Birge HE Davidson EA Eliasson PE Evans SE Frey SD Giardina CP Hopkins FM Hyvǒnen R Kirschbaum MUF Lavallee JM Leifeld J Parton WJ Megan Steinweg J Wallenstein MD Martin Wetterstedt JA Bradford MA | | 0，，： | 1 |
| 19 | Tomato transcription factors Pti4,PtiS,and Pti6 activate defense responses when expressed in Arabidopsis显示文摘 | Gu Y Q Wildermuth M C ChaEravarthy S Loh Y T Yang C He X H Hart Y Martin G B | | 0，，： | 1 |
| 20 | Phase Transition Temperature Ranges and Storage Density of Paraffin Wax Phase Change Materials显示文摘 | Bo He Viktoria Martin | 2004 | Energy2004，29，： | 1 |
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