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| 1 | Randomized controlled trial of bipolar diathermy vs ultrasonic scalpel for closed hemorrhoidectomy显示文摘AIM:To compare hemorrhoidectomy with a bipolar electrothermal device or hemorrhoidectomy using an ultrasonically activated scalpel.METHODS:Sixty patients with grade Ⅲ or Ⅳ hemorrhoids were prospectively randomized to undergo closed hemorrhoidectomy assisted by bipolar diathermy(group 1) or hemorrhoidectomy with the ultrasonic scalpel(group 2).Operative data were recorded,and patients were followed at 1,3,and 6 wk to evaluate complications.Independent assessors were assigned to obtain postoperative pain scores,oral analgesic requirement and satisfaction scores.RESULTS:Reduced intraoperative blood loss median 0.9 mL(95% CI:0.8-3.7) vs 4.6 mL(95% CI:3.8-7.0),P = 0.001 and a short operating time median 16(95% CI:14.6-18.2) min vs 31(95% CI:28.1-35.3) min,P < 0.0001 was observed in group 1 compared with group 2.There was a trend towards lower postoperative pain scores on day 1 group 1 median 2(95% CI:1.8-3.5) vs group 2 median 3(95% CI:2.6-4.2),P = 0.135.Reduced oral analgesic requirement during postoperative 24 h after operation median 1(95% CI:0.4-0.9) tablet vs 1(95% CI:0.9-1.3) tablet,P = 0.006 was observed in group 1 compared with group 2.There was no difference between the two groups in the degree of patient satisfaction or number of postoperative complications.CONCLUSION:Bipolar diathermy hemorrhoidectomy is quick and bloodless and,although as painful as closed hemorrhoidectomy with the ultrasonic scalpel,is associated with a reduced analgesic requirement immediately after operation. | Akira Tsunoda Haruki Sada Takuya Sugimoto Nobuyasu Kano Mariko Kawana Tadanori Sasaki Hideki Hashimoto | 2011 | World Journal of Gastrointestinal Surgery2011,3,10: | 6 |
| 2 | Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava显示文摘Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). The SEF of the liver was successfully resected, and the infiltrated IVC was also removed together with the liver tumor. Histopathological examination of the tumor showed typical histopathology of SEF. Immunohistochemically, the tumor was positive for vimentin. Recurrence was noted 7 mo after surgery. After chemotherapy, the recurrent tumor was resected surgically, and histopathological examination showed similar findingsto those of the primary tumor. To our knowledge, this is the first report of SEF of the liver with tumor invasion of the IVC. | Yoshito Tomimaru Hiroaki Nagano Shigeru Marubashi Shogo Kobayashi Hidetoshi Eguchi Yutaka Takeda Masahiro Tanemura Toru Kitagawa Koji Umeshita Nobuyuki Hashimoto Hideki Yoshikawa Kenichi Wakasa Yuichiro Doki Masaki Mori | 2009 | World Journal of Gastroenterology2009,15,33: | 5 |
| 3 | B?cell translocation gene 1 serves as a novel prognostic indicator ofhepatocellular carcinoma显示文摘 | Mitsuro Kanda Hiroyuki Sugimoto Shuji Nomoto Hisaharu Oya Soki Hibino Dai Shimizu Hideki Takami Ryoji Hashimoto Yukiyasu Okamura Suguru Yamada Tsutomu Fujii Goro Nakayama Masahiko Koike Michitaka Fujiwara Yasuhiro Kodera | 2015 | International Journal of Oncology2015,,2: | 3 |
| 4 | Alpha-fetoprotein before and after pegylated interferon therapy for predicting hepatocellular carcinoma development显示文摘AIM: To investigate factors that accurately predict hepatocellular carcinoma(HCC) development after antiviral therapy in chronic hepatitis C(CHC) patients. METHODS: CHC patients who received pegylated interferon and ribavirin were enrolled in this cohort study that investigated the ability of alpha-fetoprotein(AFP) to predict HCC development after interferon(IFN) therapy. RESULTS: Of 1255 patients enrolled, 665 developed sustained virological response(SVR) during mean follow-up period of 5.4 years. HCC was occurred in 89 patients, and 20 SVR patients were included. Proportional hazard models showed that HCC occurred in SVR patients showing AFP ≥ 5 ng/m L before therapy and in non-SVR patients showing AFP ≥ 5 ng/m L before and 1 year after therapy besides older age, and low platelet counts. SVR patients showing AFP ≥ 5 ng/m L before therapy and no decrease in AFP to < 5 ng/m L 1 year after therapy had significantly higher HCC incidence than non-SVR patients showing AFP ≥ 5 ng/m L before therapy and decreased AFP(P = 0.043). AFP ≥ 5 ng/m L before therapy was significantly associated with low platelet counts and high values of alanine aminotransferase(ALT) in stepwise logistic regression analysis. After age, gender, platelet count, and ALT was matched by propensity score, significantly lower HCC incidence was shown in SVR patients showing AFP < 5 ng/m L before therapy than in those showing AFP ≥ 5 ng/m L.CONCLUSION: The criteria of AFP < 5 ng/m L before and 1 year after IFN therapy is a benefical predictor for HCC development in CHC patients. | Yasuto Takeuchi Fusao Ikeda Toshiya Osawa Yasuyuki Araki Kouichi Takaguchi Youichi Morimoto Noriaki Hashimoto Kousaku Sakaguchi Tatsuro Sakata Masaharu Ando Yasuhiro Makino Shuji Matsumura Hiroki Takayama Hiroyuki Seki Shintarou Nanba Yuki Moritou Tetsuya Yasunaka Hideki Ohnishi Akinobu Takaki Kazuhiro Nouso Yoshiaki Iwasaki Kazuhide Yamamoto | 2015 | World Journal of Hepatology2015,7,19: | 3 |
| 5 | Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma显示文摘 | Shunsuke Kondo Hidenori Ojima Hitoshi Tsuda Jun Hashimoto Chigusa Morizane Masafumi Ikeda Hideki Ueno Kenji Tamura Kazuaki Shimada Yae Kanai Takuji Okusaka | 2013 | International Journal of Clinical Oncology2013,,2: | 2 |
| 6 | Effects of aging and persistent prehypertension on arterial stiffening显示文摘 | Hirofumi Tomiyama Hideki Hashimoto Chisa Matsumoto Mari Odaira Masanobu Yoshida Kazuki Shiina Mikio Nagata Akira Yamashina Nobutaka Doba Shigeaki Hinohara | 2011 | Atherosclerosis2011,,1: | 2 |
| 7 | How Do Patients and Providers React to Different Incentives in the Chinese Multiple Health Security Systems?显示文摘 | Chun-Yu Zhang Hideki Hashimoto | 2015 | Chinese Medical Journal2015,,5: | 2 |
| 8 | IL-6 negatively regulates osteoblast differentiation through the SHP2/MEK2 and SHP2/Akt2 pathways in vitro显示文摘 | Shoichi Kaneshiro Kosuke Ebina Kenrin Shi Chikahisa Higuchi Makoto Hirao Michio Okamoto Kota Koizumi Tokimitsu Morimoto Hideki Yoshikawa Jun Hashimoto | 2014 | Journal of Bone and Mineral Metabolism2014,,4: | 2 |
| 9 | Function and diagnostic value of Anosmin‐1 in gastric cancer progression显示文摘 | Mitsuro Kanda Dai Shimizu Tsutomu Fujii Satoshi Sueoka Yuri Tanaka Kazuhiro Ezaka Hideki Takami Haruyoshi Tanaka Ryoji Hashimoto Naoki Iwata Daisuke Kobayashi Chie Tanaka Suguru Yamada Goro Nakayama Hiroyuki Sugimoto Masahiko Koike Michitaka Fujiwara Yasu | 2016 | Int. J. Cancer2016,,3: | 1 |
| 10 | Translational implication of Kallmann syndrome-1 gene expression inhepatocellular carcinoma显示文摘 | Yuri Tanaka Mitsuro Kanda Hiroyuki Sugimoto Dai Shimizu Satoshi Sueoka Hideki Takami Kazuhiro Ezaka Ryoji Hashimoto Yukiyasu Okamura Naoki Iwata Chie Tanaka Suguru Yamada Tsutomu Fujii Goro Nakayama Masahiko Koike Shuji Nomoto Michitaka Fujiwara Yasuhiro | 2015 | International Journal of Oncology2015,,6: | 1 |
| 11 | Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice显示文摘 | Kosuke Ebina Kazuya Oshima Morihiro Matsuda Atsunori Fukuhara Kazuhisa Maeda Shinji Kihara Jun Hashimoto Takahiro Ochi Nirmal K. Banda Hideki Yoshikawa Iichiro Shimomura | 2008 | Biochemical and Biophysical Research Communications2008,,2: | 1 |
| 12 | Relationship Between C-Reactive Protein and Progression of Early Carotid Atherosclerosis in Hypertensive Subjects显示文摘 | Hiroyuki Hashimoto Kazuo Kitagawa Hidetaka Hougaku Hideki Etani Masatsugu Hori | 2004 | Stroke: Journal of the American Heart Association2004,,7: | 1 |
| 13 | Ginsenoside Rbl prevents MPP+-induced apoptosis in PC12ceils by stimulating estrogen receptors with consequent activation of ERKI/2,Akt and inhibition of SAPK/JNK, p38MAPK 显示文摘 | Ryo Hashimoto Yu Jing Hideki Koizumi | 2012 | Evid Based Complement Alternat Med2012,2012,69: | 1 |
| 14 | Lifetime of amorphous WO3- TiO2 thin filims 显示文摘 | Satoshi Hashimoto Hideki Matsuoka | 1991 | Thin Flims Electrochem1991,138,8: | 1 |
| 15 | Human-following mobile robot in a distributed intelligent sensor network显示文摘 | Morioka Kazuyuki Lee Joo-Ho Hashimoto Hideki | | 0,,01: | 1 |
| 16 | The impact of subjective and objective social status on psychological distress among men and women in Japan显示文摘 | Keiko Sakurai Norito Kawakami Kazue Yamaoka Hirono Ishikawa Hideki Hashimoto | 2010 | Social Science & Medicine2010,,11: | 1 |
| 17 | Upfront Thrombus Aspiration in Primary Coronary Intervention for Patients With ST-Segment Elevation Acute Myocardial Infarction显示文摘 | Yuji Ikari Masami Sakurada Ken Kozuma Shigeo Kawano Takaaki Katsuki Kazuo Kimura Takahiko Suzuki Takehiro Yamashita Akinori Takizawa Kazuo Misumi Hideki Hashimoto Takaaki Isshiki | 2008 | JACC: Cardiovascular Interventions2008,,: | 1 |
| 18 | Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone显示文摘 | Akihide Nampei Jun Hashimoto Kenji Hayashida Hideki Tsuboi Kenrin Shi Isamu Tsuji Hideaki Miyashita Takao Yamada Naomichi Matsukawa Masayuki Matsumoto Shigeto Morimoto Toshio Ogihara Takahiro Ochi Hideki Yoshikawa | 2004 | Journal of Bone and Mineral Metabolism2004,,3: | 1 |
| 19 | Population ageing and wellbeing: lessons from Japan's long-term care insurance policy显示文摘 | NANAKO TAMIYA HARUKO NOGUCHI AKIHIRO NISHI MICHAEL R REICH NAOKI IKEGAMI HIDEKI HASHIMOTO KENJI SHIBUYA ICHIRO KAWACHI JOHN CREIGHTON CAMPBELL | 2011 | The Lancet2011,,378: | 1 |
| 20 | Intelligent control for human-machine systems显示文摘 | Hideki Hashimoto | 1996 | IEEE Trans on Mechatro-nics1996,1,1: | 1 |