|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Strategies to prevent hypertrophic scar formation:a review of therapeutic interventions based on molecular evidence显示文摘Once scar tissues mature,it is impossible for the surrounding tissue to regenerate normal dermal tissue.Therefore,it is essential to understand the fundamental mechanisms and establish effective strategies to inhibit aberrant scar formation.Hypertrophic scar formation is considered a result of the imbalance between extracellular matrix synthesis and degradation during wound healing.However,the underlying mechanisms of hypertrophic scar development are poorly understood.The purpose of this review was to outline the management in the early stage after wound healing to prevent hypertrophic scar formation,focusing on strategies excluding therapeutic agents of internal use.Treatment aimed at molecular targets,including cytokines,will be future options to prevent and treat hypertrophic scars.More basic studies and clinical trials,including combination therapy,are required to investigate the mechanisms and prevent hypertrophic scar formation. | Eri Shirakami Sho Yamakawa Kenji Hayashida | 2020 | Burns & Trauma2020，8，1： | 18 |
| 2 | Advances in surgical applications of growth factors for wound healing显示文摘Growth factors have recently gained clinical importance for wound management.Application of recombinant growth factors has been shown to mimic cellmigration,proliferation,and differentiation in vivo,allowing for external modulation of the healing process.Perioperative drug delivery systems can enhance the biological activity of these growth factors,which have a very short in vivo half-life after topical administration.Although the basic mechanisms of these growth factors are well understood,most have yet to demonstrate a significant impact in animal studies or small-sized clinical trials.In this review,we emphasized currently approved growth factor therapies,including a sustained release system for growth factors,emerging therapies,and future research possibilities combined with surgical procedures.Approaches seeking to understand wound healing at a systemic level are currently ongoing.However,further research and consideration in surgery will be needed to provide definitive confirmation of the efficacy of growth factor therapies for intractable wounds. | Sho Yamakawa Kenji Hayashida | 2019 | Burns & Trauma2019，7，1： | 11 |
| 3 | Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia–reperfusion injury显示文摘 | Kentaro Hayashida Motoaki Sano Ikuroh Ohsawa Ken Shinmura Kayoko Tamaki Kensuke Kimura Jin Endo Takaharu Katayama Akio Kawamura Shun Kohsaka Shinji Makino Shigeo Ohta Satoshi Ogawa Keiichi Fukuda | 2008 | Biochemical and Biophysical Research Communications2008，，1： | 2 |
| 4 | Bone and soft tissue tumors presenting as sciatic notch dumbbell masses: A critical differential diagnosis of sciatica显示文摘AIM To study the clinical findings and characteristic features in sciatic notch dumbbell tumors(SNDTs).METHODS We retrospectively reviewed the clinical outcomes and characteristic features of consecutive cases of SNDTs(n = 8). RESULTS Buttock masses occurred in three patients with SNDT(37.5%). Severe buttock tenderness and pain at rest were observed in seven patients with SNDTs(87.5%). Remarkably, none of the patients with SNDTs experienced back pain. Mean tumor size was 8.4 ± 2.0 cm(range, 3.9 to 10.6 cm) and part of the tumor mass was detected in 2 patients in the sagittal view of lumbar magnetic resonance imaging(MRI).CONCLUSION The clinical information regarding to SNDTs is scarce. The authors consider that above mentioned characteristic findings may facilitate the suspicion of pelvic pathology and a search for SNDT by MRI or computed tomography should be considered in patients presenting with sciatica without evidence of spinal diseases. | Yoshihiro Matsumoto Tomoya Matsunobu Katsumi Harimaya Kenichi Kawaguchi Mitsumasa Hayashida Seiji Okada Toshio Doi Yukihide Iwamoto | 2016 | World Journal of Clinical Oncology2016，7，5： | 2 |
| 5 | Obstruction of st jude medical valves in the aortic position: histology and immunohistochemistry of pannus显示文摘 | Hideki Teshima Nobuhiko Hayashida Hirohisa Yano Masaru Nishimi Eiki Tayama Shuji Fukunaga Hidetoshi Akashi Takemi Kawara Shigeaki Aoyagi | 2003 | The Journal of Thoracic and Cardiovascular Surgery2003，，2： | 2 |
| 6 | The influence of donor age on liver regeneration and hepatic progenitor cell populations显示文摘 | Yoshihiro Ono Shigeyuki Kawachi Tetsu Hayashida Masatoshi Wakui Minoru Tanabe Osamu Itano Hideaki Obara Masahiro Shinoda Taizo Hibi Go Oshima Noriyuki Tani Kisyo Mihara Yuko Kitagawa | 2011 | Surgery2011，，2： | 2 |
| 7 | TGF-beta signal transduction and mesangial cell fibrogenesis显示文摘 | Schnaper HW Hayashida T Hubchak SC | 2003 | Am J Physiol Renal Physiol2003，284，2： | 2 |
| 8 | Quantitative relation between feces protein particles and rice protein bodies 显示文摘 | Hayashida S Hongo M | 1975 | J Agric Chem Soc Jpn1975，49，： | 1 |
| 9 | Mutations in the TRKA/NGFreceptor gene in patients with congenital insensitivity to pain with anhidrosis 显示文摘 | Tsuruta M Hayashida Y | 1996 | Nat Genet1996，13，： | 1 |
| 10 | Physiological properties of yeast cells grown in proteolipid supplemented media显示文摘 | HAYASHIDA S FENG D D HONGO M | 1975 | Agric Biol Chem1975，39，： | 1 |
| 11 | Histopathological findings of the noreflow phenomenon following coronary intervention for acute coronary syndrome 显示文摘 | Kawano H Hayashida T Ohtani H | 2005 | Int Heart J2005，46，2： | 1 |
| 12 | Lectin-like ox- idized LDL receptor-1 (LOX-1) supports adhesion of mononuclear leukocytes and a monocyte-like cell THP-I cell under static and flow conditions 显示文摘 | Hayashida K Kume N Mimami M | 2002 | FEBS Lett2002，511，13： | 1 |
| 13 | Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16 (INK4a) and Cdk2/cyclin E complex activation显示文摘 | Suzuki A Hayashida M Ito T | 2000 | Oncogene2000，19，： | 1 |
| 14 | TGF-β1 activates MAP kinases in human mesangial cells: a possible role in collagen expression显示文摘 | Hayashida T Poncelet AC Hubchak SC Schnaper HW | 1999 | Kedney Int1999，56，： | 1 |
| 15 | High ambient glucose enhances sensitivity to TGF-beta 1 via extracellular signal-regulated kinase and protein kinase C activities in human mesangial cells显示文摘 | Hayashida T Schnaper HW | 2004 | J Am Soc Nephrol2004，15，： | 1 |
| 16 | Identification of a human peripheral blood monocyte subsets that differentiates into osteoclasts 显示文摘 | Komano Y Nanki T Hayashida K | 2006 | Arthritis Res Ther2006，8，5： | 1 |
| 17 | Survlvin initiates cell cycle entry by the competitive interaction with Cdk4/p16 (INK4a) and Cdk2/cyclin E complex activation 显示文摘 | Suzuki A Hayashida M Ito T | 2000 | Oncogene2000，19，29： | 1 |
| 18 | Lectin-like oxidized LDL receptor-1 ( LOX-1 ) supports adhesion of mononuclear leukocytes and a monocyte-like cell line THP-1 cells under static and flow conditions 显示文摘 | Hayashida K Kume N Minami M | 2002 | FEBS Letters2002，511，13： | 1 |
| 19 | Cytokine/chemokine profiles contribute to understanding the pathogenesis and diagnosis of primary Sjǒgren's syndrome显示文摘 | Moriyama M Hayashida JN Toyoshima T | | 0，，1： | 1 |
| 20 | Effect of bird ingestion on seed germination of Sorbus commi:cta 显示文摘 | YAGIHASHI T HAYASHIDA M MIYAMOTO T | 1998 | Oecologia1998，114，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员