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| 1 | 香辛料提取物及其在肉制品抑菌防腐中的应用进展显示文摘肉品腐败被认为是食品工业中最重要的经济和健康问题之一,而抑菌防腐剂的应用是阻止化学变质和微生物腐败的主要手段。由于消费者对化学防腐剂安全性的担忧,相对更为安全的天然或“绿色”的替代品越来越受到关注。研究表明,天然香辛料提取物具有显著的抑菌性和抗氧性,其作用机理是基于对微生物细胞壁的降解、细胞膜的破坏、膜蛋白的损伤,以及细胞内容物的泄漏和质子源的消耗等几个靶点的作用。该研究从香辛料提取物的来源、提取方法、主要活性成分、抑菌机制、体外抑菌实验和协同作用进行概述,并重点总结了天然香辛料提取物在肉品中的抑菌防腐作用及其应用的研究进展,以期为肉制品加工寻求具更为安全而有效的防腐保鲜方法提供参考。 | 杨轶浠 崔钊伟 王卫 Jaekel Carsten Stephan Herbert 张佳敏 刘雅宁 郭育涛 | 2022 | 现代食品科技2022，38，3： | 8 |
| 2 | Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience显示文摘 | Michael Lell Mohamed Marwan Tiziano Schepis Tobias Pflederer Katharina Anders Thomas Flohr Thomas Allmendinger Willi Kalender Dirk Ertel Carsten Thierfelder Axel Kuettner Dieter Ropers Werner G. Daniel Stephan Achenbach | 2009 | European Radiology2009，，11： | 2 |
| 3 | Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death显示文摘 | Alexander Seiler Manuela Schneider Heidi F?rster Stephan Roth Eva K. Wirth Carsten Culmsee Nikolaus Plesnila Elisabeth Kremmer Olof R?dmark Wolfgang Wurst Georg W. Bornkamm Ulrich Schweizer Marcus Conrad | 2008 | Cell Metabolism2008，，3： | 2 |
| 4 | Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity显示文摘Dear Editor,Next-generation sequencing revealed that the majority of the human genome is transcribed but has no coding function.It is estimated that.30000 long noncoding RNAs(lncRNAs)are expressed in humans,but their functions are largely unknown(Suckau et al.,2009;Rinn and Chang,2012;Poller et al.,2013).Consideration of noncoding genomic elements in pathogenetic studies is warranted and enabled by technological advances allowing comprehensive transcriptome mapping of protein-coding genes as well as small and long ncRNAs. | Martina Gast Blanche Schroen Antje Voigt Jan Haas Uwe Kuehl Dirk Lassner Carsten Skurk Felicitas Escher Xiaomin Wang Adelheid Kratzer Katharina Michalik Anna Papageorgiou Tim Peters Madlen Loebel Sabrina Wilk Nadine Althof Kannanganattu VPrasanth Hugo Katus Benjamin Meder Shinichi Nakagawa Carmen Scheibenbogen Heinz-Peter Schultheiss Ulf Landmesser Stefanie Dimmeler Stephane Heymans Wolfgang Poller | 2016 | Journal of Molecular Cell Biology2016，8，2： | 2 |
| 5 | Risk prediction models for biochemical recurrence after radical prostatectomy using prostate-specific antigen and Gleason score显示文摘为预言前列腺癌症的风险的许多计算机模型被开发了为生物化学的复发(BCR ) 的预言包括。然而,在一个 BCR 免费时期是稀罕的以后,在单个时间点为单个 BCR 免费概率当模特儿。从经历了 laparoscopic 激进分子前列腺切除术( LRP )的 1656 个病人的后续数据被用来模型使用开发一个人工的神经网络( ANN )预言 BCR 并且把它与逻辑回归( LR )作比较临床、病理学的参数,前列腺特定的抗原( PSA ),边缘地位( R0/1 ),病理学的阶段(磅),和格利森分数( GS )。为在在操作,另外的 ANN,和 LR 以后的任何给定的时间的单个 BCR 预言,模型每 6 个月被计算多达 7.5 年后续。在为 ANN (0.754 ) 和 LR 的操作特征(巨鸟) 曲线(AUC ) 建模的接收装置(0.755 ) 下面的区域计算了立即后面的 LRP,为 GS 比那大(AUC:0.715;P = 0.0015 和 0.001 ) ,磅或 PSA (AUC:0.619;P 总是 < 0.0001 ) 独自一个。GS 比 PSA 更好预言了 BCR (P = 0.0001 ) ,但是 ANN 和 LR 模型之间没有差别(P = 0.39 ) 。我们的 ANN 和 LR 模型从激进的前列腺切除术预言了单个 BCR 风险多达 10 年手术后。ANN 和 LR 模型同等地并且显著地独自与 PSA 和 GS 相比改进了 BCR 的预言。当 GS 和 ANN 产量价值被联合时,更精确的 BCR 预言是可能的,特别在有 GS ≥ 的高风险的病人; 7。 | Xin-Hai Hu Henning Cammann Hellmuth-A Meyer Klaus Jung Hong-Biao Lu Natalia Levas Ahmed Magheli Carsten Stephan Jonas Busch | 2014 | Asian Journal of Andrology2014，16，6： | 2 |
| 6 | Hypermethylation of the CDKN2/p16INK4A promotor in thyroid carcinogenesis显示文摘 | CARSTEN B STEPHAN Z CLAUDIA Q | 2003 | Pathol Res Pract2003，199，6： | 1 |
| 7 | Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience显示文摘 | Michael Lell Mohamed Marwan Tiziano Schepis Tobias Pflederer Katharina Anders Thomas Flohr Thomas Allmendinger Willi Kalender Dirk Ertel Carsten Thierfelder Axel Kuettner Dieter Ropers Werner G. Daniel Stephan Achenbach | 2009 | European Radiology2009，，11： | 1 |
| 8 | The Surgical Treatment of the Lumbar Disc Prolapse: Nucleotomy With Additional Transpedicular Dynamic Stabilization Versus Nucleotomy Alone显示文摘 | Michael Putzier Sascha V. Schneider Julia F. Funk Stephan W. Tohtz Carsten Perka | 2005 | Spine2005，，5： | 1 |
| 9 | Redox-dependent fractionation of iron isotopes in suspensions of a groundwater-influenced soil显示文摘 | Stephan Schuth Julia Hurra? Carsten Münker Tim Mansfeldt | 2014 | Chemical Geology2014，，： | 1 |
| 10 | Long-term simulation of effects of energy crop cultivation on nitrogen leaching and surface water quality in Saxony/Germany显示文摘 | Michael Gebel Stefan Halbfass Stephan Bürger Carsten Lorz | 2013 | Regional Environmental Change2013，，2： | 1 |
| 11 | The Ratio of Prostate-Specific Antigen (PSA) to Prostate Volume (PSA Density) as a Parameter to Improve the Detection of Prostate Carcinoma in PSA Values in the Range of <4 ng/ml显示文摘 | Carsten Stephan Greta Stroebel Marc Heinau | 2005 | Cancer2005，104，5： | 1 |
| 12 | Decreased RECK and Increased EMMPRIN Expression in Urothelial Carcinoma of the Bladder Are Associated with Tumor Aggressiveness显示文摘 | Wittschieber Daniel Stenzinger Albrecht Klauschen Frederick Stephan Carsten Jung Klaus Erbersdobler Andreas Rabien Anja | 2011 | EN2011，，3： | 1 |
| 13 | Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla显示文摘 | Birgit Simon Stephan Schmidt Carsten Lukas Jürgen Gieseke Frank Tr?ber Dirk L. Knol Winfried A. Willinek Jeroen J. G. Geurts Hans H. Schild Frederik Barkhof Mike P. Wattjes | 2010 | European Radiology2010，，7： | 1 |
| 14 | TGFβ functionalized starPEG-heparin hydrogels modulate human dermal fibroblast growth and differentiation显示文摘 | Akira Watarai Lucas Schirmer Stephan Th?nes Uwe Freudenberg Carsten Werner Jan C. Simon Ulf Anderegg | 2015 | Acta Biomaterialia2015，，： | 1 |
| 15 | Gene expression studies in prostate cancer tissue: which reference gene should be selected for normalization?显示文摘 | Falk Ohl Monika Jung Chuanliang Xu Carsten Stephan Anja Rabien Mick Burkhardt Andreas Nitsche Glen Kristiansen Stefan A. Loening Aleksandar Radoni? Klaus Jung | 2005 | Journal of Molecular Medicine2005，，12： | 1 |
| 16 | Measurement of Serum Levels of MIC1 Combinded with Prostate-Specific Antigen Improves Prostate Cancer Diagnosis 显示文摘 | Daid A Brown Carsten Stephan Robyn L Ward | 2006 | Clin Cancer Res2006，12，1： | 1 |
| 17 | Long-Term Effectiveness of Azathioprine in IBD Beyond 4 Years: A European Multicenter Study in 1176 Patients显示文摘 | Martin H. Holtmann Frank Krummenauer Christina Claas Kristina Kremeyer Dirk Lorenz Olivia Rainer Iris Vogel Ulrich B?cker Stephan B?hm Carsten Büning Rainer Duchmann Guido Gerken Hans Herfarth Norbert Lügering Wolfgang Kruis Max Reinshagen Jan Schmidt And | 2006 | Digestive Diseases and Sciences2006，，9： | 1 |
| 18 | Hydroxyapatite scaffolds for bone tissue engineering made by 3D printing显示文摘 | Barbara Leukers Hülya Gülkan Stephan H. Irsen Stefan Milz Carsten Tille Matthias Schieker Hermann Seitz | 2005 | Journal of Materials Science: Materials in Medicine2005，，12： | 1 |
| 19 | Is hepatic steatosis associated with left ventricular mass index increase in the general population?显示文摘AIM To investigate the association between hepatic steatosis and change in left ventricular mass index(LVMI) over five years, and examine whether systolic and diastolic blood pressures are mediators of the association between hepatic steatosis and LVMI using a general population sample.METHODS We analyzed data from the Study of Health in Pomerania. The study population comprised 1298individuals aged 45 to 81 years. Hepatic steatosis was defined as the presence of a hyperechogenic pattern of the liver together with elevated serum alanine transferase levels. Left ventricular mass was determined echocardiographically and indexed to height2.7. Path analyses were conducted to differentiate direct and indirect paths from hepatic steatosis to LVMI encompassing systolic and diastolic blood pressure as potential mediating variables.RESULTS Hepatic steatosis was a significant predictor for all measured echocardiographic characteristics at baseline. Path analyses revealed that the association of hepatic steatosis with LVMI change after five years was negligibly small(β =-0.12, s.e. = 0.21, P = 0.55). Systolic blood pressure at baseline was inversely associated with LVMI change(β =-0.09, s.e. = 0.03, P < 0.01), while no association between diastolic blood pressure at baseline and LVMI change was evident(β = 0.03, s.e. = 0.05, P = 0.56). The effect of the indirect path from hepatic steatosis to LVMI via systolic baseline blood pressure was small(β =-0.20, s.e. = 0.10, P = 0.07). No indirect effect was observed for the path via diastolic baseline blood pressure(β = 0.03, s.e. = 0.06, P = 0.60). Similar associations were observed in the subgroup of individuals not receiving beta-blockers, calcium channel blockers, or drugs acting on the reninangiotensin system.CONCLUSION Baseline associations between hepatic steatosis and LVMI do not extend to associations with LVMI change after five years. More studies are needed to study the longitudinal effects of hepatic steatosis on LVMI. | Katharina Piontek Carsten O Schmidt Sebastian E Baumeister Markus M Lerch Julia Mayerle Marcus Dorr Stephan B Felix Henry Volzke | 2017 | World Journal of Hepatology2017，9，19： | 0 |
| 20 | Tip-and Laser-based 3D Nanofabrication in Extended Macroscopic Working Areas显示文摘The field of optical lithography is subject to intense research and has gained enormous improvement.However,the effort necessary for creating structures at the size of 20 nm and below is considerable using conventional technologies.This effort and the resulting financial requirements can only be tackled by few global companies and thus a paradigm change for the semiconductor industry is conceivable:custom design and solutions for specific applications will dominate future development(Fritze in:Panning EM,Liddle JA(eds)Novel patterning technologies.International society for optics and photonics.SPIE,Bellingham,2021.http://gffzzd3cc09b8251d45dfsn6fwckkccow669pc.ffgz.tsg.suse.edu.cn/10.1117/12.2593229).For this reason,new aspects arise for future lithography,which is why enormous effort has been directed to the development of alternative fabrication technologies.Yet,the technologies emerging from this process,which are promising for coping with the current resolution and accuracy challenges,are only demonstrated as a proof-of-concept on a lab scale of several square micrometers.Such scale is not adequate for the requirements of modern lithography;therefore,there is the need for new and alternative cross-scale solutions to further advance the possibilities of unconventional nanotechnologies.Similar challenges arise because of the technical progress in various other fields,realizing new and unique functionalities based on nanoscale effects,e.g.,in nanophotonics,quantum computing,energy harvesting,and life sciences.Experimental platforms for basic research in the field of scale-spanning nanomeasuring and nanofabrication are necessary for these tasks,which are available at the Technische Universitiit Ilmenau in the form of nanopositioning and nanomeasuring(NPM)machines.With this equipment,the limits of technical structurability are explored for high-performance tip-based and laser-based processes for enabling real 3D nanofabrication with the highest precision in an adequate working range of several thousand cubic millimeters. | Ingo Ortlepp Thomas Frohlich Roland FuBl Johann Reger Christoph Schaffel Stefan Sinzinger Steffen Strehle ReneTheska Lena Zentner Jens-Peter Zollner Ivo WRangelow Carsten Reinhardt Tino Hausotte Xinrui Cao Oliver Dannberg Florian Fern David Fischer Stephan Gorges Martin Hofmann Johannes Kirchner Andreas Meister Taras Sasiuk Ralf Schienbein Shraddha Supreeti Laura Mohr-Weidenfeller Christoph Weise Christoph Reuter Jaqueline Stauffenberg Eberhard Manske | 2021 | Nanomanufacturing and Metrology2021，4，3： | 0 |
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