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    题名 作者 年代 出处 被引量
1老年人重要社会支持的特点及其与老化态度的关系显示文摘采用重要他人和老化态度问卷测查了441名老年人的社会支持和老化态度情况,并且从支持的数量和质量角度以及实际支持和期望支持的角度细致考察了社会支持与老化态度的关系。结果表明:(1)老年人的支持来源符合层级补偿模型;(2)不同性别、年龄及受教育水平的老年人在重要社会支持上存在显著差异;(3)老年人从重要他人那里获得的实际社会支持的质量越高,老化态度越积极。张明妍 王大华 Mick Power Ken Laidlaw 2011心理科学2011,34,2:29
2Narrative overview of animal and human brucellosis in Morocco: intensification of livestock production as a driver for emergence?显示文摘Brucellosis is one of the most widespread zoonoses in the world caused by several species of the genus Brucella.The disease,eradicated in many developed countries,is a re-emerging neglected zoonosis endemic in several zones especially in the Mediterranean region,impacting on human health and livestock production.A One Health approach could address brucellosis control in Morocco but scarcity of reliable epidemiological data,as well as underreporting,hinders the implementation of sustainable control strategies.Surveillance and control policies implemented by the Moroccan government in domestic animals(cattle and small ruminants)in the last few decades are assessed for disease impact.This study considers the origins of animal brucellosis in Morocco and the potential for emergence of brucellosis during a shift from extensive to intensive livestock production.Marie J.Ducrotoy Khaoula Ammary Hicham Ait Lbacha Zaid Zouagui Virginie Mick Laura Prevost Ward Bryssinckx Susan CWelburn Abdelali Benkirane 2015Infectious Diseases of Poverty2015,4,1:9
3Molecular mechanisms of metastasis in prostate cancer显示文摘前列腺癌症(PCa ) 优先地转移到轴的骨骼的骨头髓基质。这项活动是 PCa 病态和死亡的主要原因。PCa 转移的准确机制当前是未知的,尽管可观的进步在在这进程决定关键播放器被取得了。在这评论,我们在场驾驶 PCa 转移到骨头的分子的过程的当前的理解。Noel W. Clarke Claire A. Hart Mick D. Brown 2009Asian Journal of Andrology2009,11,1:7
4Critical analysis of the literature investigating urogenital function preservation following robotic rectal cancer surgery显示文摘AIM To analyses the current literature regarding the urogenital functional outcomes of patients receiving robotic rectal cancer surgery. METHODS A comprehensive literature search of electronic databases was performed in October 2015. The following search terms were applied: 'rectal cancer' or 'colorectal cancer' and robot* or 'da Vinci' and sexual or urolog* or urinary or erect* or ejaculat* or impot* or incontinence. All original studies examining the urological and/or sexual outcomes of male and/or female patients receiving robotic rectal cancer surgery were included. Reference lists of all retrieved articles were manually searched for further relevant articles. Abstracts were independently searched by two authors. RESULTS Fifteen original studies fulfilled the inclusion criteria. A total of 1338 patients were included; 818 received robotic, 498 laparoscopic and 22 open rectal cancer surgery. Only 726(54%) patients had their urogenital function assessed via means of validated functional questionnaires. From the included studies, three found that robotic rectal cancer surgery leads to quicker recovery of male urological function and five of male sexual function as compared to laparoscopic surgery. It is unclear whether robotic surgery offers favourable urogenital outcomes in the long run for males. In female patients only two studies assessed urological and threesexual function independently to that of males. In these studies there was no difference identified between patients receiving robotic and laparoscopic rectal cancer surgery. However, in females the presented evidence was very limited making it impossible to draw any substantial conclusions. CONCLUSION There seems to be a trend towards earlier recovery of male urogenital function following robotic surgery. To evaluate this further, larger well designed studies are required.Sofoklis Panteleimonitis Jamil Ahmed Mick Harper Amjad Parvaiz 2016World Journal of Gastrointestinal Surgery2016,8,11:7
5河口海岸中长时间尺度动力地貌系统模拟研究与进展显示文摘我国河口海岸动力沉积和动力地貌研究以沉积学和地貌学的方法侧重静态描述,动力地貌相互作用的定量研究不多,与缺少动力地貌模型技术有关。本文介绍了中长时间尺度的河口海岸动力地貌模型技术及其发展和应用,讨论了决定动力地貌演变的泥沙余输运及引起泥沙余输运的主要动力因子,介绍了动力地貌模型的应用进展,进而分析了河口海岸地貌过程的机制和地貌平衡系统。本文指出对淤泥质及复杂动力条件下的河口海岸动力地貌过程还有待进一步研究。郭磊城 何青 Dano ROELVINK Zhengbing WANG Mick VAN DER WEGEN 2013地理学报2013,68,9:7
6Robotic rectal cancer surgery:Results from a European multicentre case series of 240 resections and comparative analysis between cases performed with the da Vinci Si and Xi systems显示文摘Introduction:Robotic systems are designed to address the limitations of laparoscopic surgery,leading to a growing interest in robotic rectal surgery.However,certain technical limitations associated with the previous systems(da Vinci S&Si)have arguably slowed down its wholesale adoption.The latest robotic platform,the da Vinci Xi,addresses these limitations.This study aims to examine the short-term surgical outcomes of 240 single-docking fully-robotic rectal cancer resections and compare the outcomes of cases performed with the da Vinci Xi vs Si systems.Materials and methods:All consecutive patients receiving robotic rectal cancer resections from three centres between 2013 and 2018 were identified from prospectively collated databases.The baseline characteristics and short-term surgical outcomes are presented and the da Vinci Xi vs Si system outcomes are analysed.Results:A total of 240 patients were identified(124 Si,116 Xi).Median operation-time and length-of-stay were 260 minutes and 6 days respectively.Conversion and 30-day mortality rates were 0.The da Vinci Si vs Xi system analysis shows that operation-time was lower in the Si group(230 vs 300 min,p=0.000)but length-of-stay,lymph node yield and circumferential resection margin favoured the Xi group(7 vs 5 days,p=0.010;17 vs 21,p=0.000;92.7%vs 99.1%,p=0.020).Conclusion:Single-docking fully-robotic rectal cancer surgery is safe,feasible and can lead to good shortterm outcomes,making it a good alternative to laparoscopic rectal cancer surgery.The new systems technological advances may result in better short-term outcomes but further larger scale observational studies are required if we are to reach such a conclusion.Sofoklis Panteleimonitis Oliver Pickering Mukhtar Ahmad Mick Harper Tahseen Qureshi Nuno Figueiredo Amjad Parvaiz 2020Laparoscopic, Endoscopic and Robotic Surgery2020,3,1:5
72010-2015年全球实验室网络支持的消除麻疹和风疹工作的进展显示文摘2012年,世界卫生大会(World Health Assembly)签署全球疫苗行动计划(Global Vaccine Action Plan,GVAP),该计划旨在2020年前消除世界卫生组织(World Health Qrganization,WHO)5个区域的麻疹和风疹。2013年9月,WHO 6个区域的所有国家都已确立消除麻疹的目标,其中3个区域还确立了消除风疹和先天性风疹综合征的目标.mick n.mulders paul a.rota joseph p.icenogle kevin e.brown makoto takeda gloria j.rey myriam c.ben mamou annick r.g.a.dosseh charles r.byabamazima hinda j.ahmed sirima pattamadilok yan zhang marta gacic-dobo peter m.strebel james l.goodson 周惠嘉(翻译) 2018上海预防医学2018,30,2:4
8中国脊髓灰质炎Ⅰ型病毒VP1/2A区变异的分子流行病学研究显示文摘应用基因测序法对我国12个省24份脊髓灰质炎1型病毒标本散了VP1/2A片段的测序工作,并与疫苗株sabin 1型参考株的序列,我国台湾省和其他国家15株病毒的序列做了比较。由计算机PCGene程序分析处理,构建出两株关系树,初步揭示了我国大陆6个基因型病毒之间,以及它们与台湾省和其他国家病毒之间的分子流行病学关系。郑渡平 张礼璧 方肇寅 杨辰夫 Mick N.Mulders Mark A.Pallansch Olen M.Kew 1993病毒学报1993,9,4:3
9Simplified three-dimensional culture system for long-term expansion of embryonic stem cells显示文摘AIM: To devise a simplified and efficient method for long-term culture and maintenance of embryonic stem cells requiring less frequent passaging. METHODS: Mouse embryonic stem cells(ESCs) labeled with enhanced yellow fluorescent protein were cultured in three-dimensional(3-D) self-assembling scaffolds and compared with traditional two-dimentional(2-D) culture techniques requiring mouse embryonic fibroblast feeder layers or leukemia inhibitory factor. 3-D scaffolds encapsulating ESCs were prepared by mixing ESCs with polyethylene glycol tetra-acrylate(PEG-4-Acr) and thiolfunctionalized dextran(Dex-SH). Distribution of ESCs in 3-D was monitored by confocal microscopy. Viability and proliferation of encapsulated cells during long-term culture were determined by propidium iodide as well as direct cell counts and PrestoB lue(PB) assays. Genetic expression of pluripotency markers(Oct4, Nanog, Klf4, and Sox2) in ESCs grown under 2-D and 3-D cultureconditions was examined by quantitative real-time polymerase chain reaction. Protein expression of selected stemness markers was determined by two different methods, immunofluorescence staining(Oct4 and Nanog) and western blot analysis(Oct4, Nanog, and Klf4). Pluripotency of 3-D scaffold grown ESCs was analyzed by in vivo teratoma assay and in vitro differentiation via embryoid bodies into cells of all three germ layers. RESULTS: Self-assembling scaffolds encapsulating ESCs for 3-D culture without the loss of cell viability were prepared by mixing PEG-4-Acr and Dex-SH(1:1 v/v) to a final concentration of 5%(w/v). Scaffold integrity was dependent on the degree of thiol substitution of Dex-SH and cell concentration. Scaffolds prepared using Dex-SH with 7.5% and 33% thiol substitution and incubated in culture medium maintained their integrity for 11 and 13 d without cells and 22 ± 5 d and 37 ± 5 d with cells, respectively. ESCs formed compact colonies, which progressively increased in size over time due to cell proliferation as determined by confocal microscopy and PB staining. 3-D scaffold cultured ESCs expressed significantly higher levels(P < 0.01) of Oct4, Nanog, and Kl4, showing a 2.8, 3.0 and 1.8 fold increase, respectively, in comparison to 2-D grown cells. A similar increase in the protein expression levels of Oct4, Nanog, and Klf4 was observed in 3-D grown ESCs. However, when 3-D cultured ESCs were subsequently passaged in 2-D culture conditions, the level of these pluripotent markers was reduced to normal levels. 3-D grown ESCs produced teratomas and yielded cells of all three germ layers, expressing brachyury(mesoderm), NCAM(ectoderm), and GATA4(endoderm) markers. Furthermore, these cells differentiated into osteogenic, chondrogenic, myogenic, and neural lineages expressing Col1, Col2, Myog, and Nestin, respectively. CONCLUSION: This novel 3-D culture system demonstrated long-term maintenance of mouse ESCs without the routine passaging and manipulation necessary for traditional 2-D cell propagation.Christina McKee Mick Perez-Cruet Ferman Chavez G Rasul Chaudhry 2015World Journal of Stem Cells2015,7,7:2
10新西兰的负鼠——一场尚未完结的与外来入侵有袋类的较量(英文)显示文摘为发展毛皮工业 ,新西兰 19世纪中叶从澳大利亚引入刷尾负鼠 (Trichosurusvulpecula) ,后成为新西兰一大害兽。刷尾负鼠不仅因破坏当地植被、捕食鸟蛋等而严重影响了新西兰的生物多样性 ,而且因其传播结核病菌对当地畜牧业造成了很大损失。新西兰每年花费巨额资金来控制这一害兽。虽然刷尾负鼠在一些孤立的岛屿和重点自然保护区已完全被消灭或得到有效的控制 ,但在新西兰大部分地区其分布却还在扩展 ,依然威胁着新西兰的生物多样性和农牧业生产。传统的控制方法包括兽夹捕杀、射杀和药物灭杀 ,其效果不佳的主要原因是 :1)受资金的限制 ;2 )小面积控制后因为种群密度减小 ,负鼠的生育率、存活率随之增高。加上新个体从周围迁入 ,种群数量迅速恢复。生物防治特别是免疫绝育法被认为是经济、人道及有效的方法。新的研究结果证明刷尾负鼠具有一雄多雌的繁殖方式 ,而且在雌兽被绝育后 ,种群中雄兽与雌兽之比率反而增高。因此雌兽绝育可能不会降低雌雄负鼠之间的接触频率。这些研究结果表明免疫绝育控制刷尾负鼠是很有前景的。纪维红 Mick Clout 2002生物多样性2002,10,1:2
11Social Vulnerability to Climate Change and the Architecture of Entitlements显示文摘W. Neil Adger P. Mick Kelly 1999Mitigation and Adaptation Strategies for Global Change (-)1999,,3:2
12火灾下钢结构的设计显示文摘对于预测真实火灾及由其所引起的钢结构的温度和结构分析,人们已经做了大量的研究并取得了较大的进展。本文通过对一些已完工的或正在建造的项目进行的工程咨询,对此研究的应用进行了探索。这些项目中包括英国Glaxo SmithKline总部所做的Cardington抗火试验以及Sheffield和其他大学的研究。文中同时还描述了一系列外部钢结构无保护的建筑物。所有这些项目的主要目的是对这种新的处于发展中的技术进行风险评估和工程审核。要获得文中给出的方法的有关信息可参考结构工程师协会(英国)的网站。Mick Green 2003建筑钢结构进展2003,5,2:2
13Bowen's diease显示文摘Lee M Mick MM 1993Clin Dermatol1993,11,1:1
14Of Ivory Towers and Infobahns显示文摘 Kevin & Doherty Mick 1995Computer-Mediated Communication Magazine1995,9,1:1
15Employee Involvement and Participation:Developing the Concept of Institutional Embeddedness Using WERS2004显示文摘Annette C Mick M Suterc J 0,,10:1
16Phase Ⅰ study of the CD40 agonist antibody CP-870,893 combined with carboplatin and paclitaxel in patients with advanced solid tumors显示文摘Vonderheide RH Burg JM Mick R 0,,01:1
17Intraoperative radiation therapy(IORT) in primary locally advanced and recurrent carcino- ma of the rectum at a non-dedicated facility 显示文摘Hesselmann S Micke O BrueWer M 2003Anticancer Res2003,23,2:1
18Measuring national economic performance without using prices显示文摘Mick Common 2007Ecological Economics2007,,1:1
19Coordinating Hun- dreds of Cooperative, Autonomous Vehicles in Warehouses显示文摘Peter R Wurman Raffaello D 'Andrea Mick Mountz 2008AI Mag- azine2008,29,1:1
20Policy,Politics and Path Dependency:Sport Development in Australia and Finland显示文摘Mick G Shane C 2008Sport Management Review2008,11,3:1
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