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| 1 | Transmission Dynamics of an Outbreak of the COVID-19 Delta Variant B.1.617.2——Guangdong Province,China,May-June 2021显示文摘On May 21,2021,a local case of coronavirus disease 2019(COVID-19)was confirmed in a 75-year-old woman(experienced onset of symptoms on May 18)in Liwan District,Guangzhou City,Guangdong Province,China.The number of infections has increased in the following 10 days and led to 5 generations of transmission. | Meng Zhang Jianpeng Xiao Aiping Deng Yingtao Zhang Yali Zhuang Ting Hu Jiansen Li Hongwei Tu Bosheng Li Yan Zhou Jun Yuan Lei Luo Zimian Liang Youzhi Huang Guoqiang Ye Mingwei Cai Gongli Li Bo Yang Bin Xu Ximing Huang Yazun Cui Dongsheng Ren Yanping Zhang Min Kang Yan Li | 2021 | China CDC weekly2021，3，27： | 51 |
| 2 | Psychological impact of the COVID-19 pandemic on healthcare workers:a cross-sectional study in China显示文摘Background Healthcare workers fighting against the coronavirus disease 2019(COVID-19)pandemic are under tremendous pressure,which puts them at an increased risk of developing psychological problems.Aims This study aimed to investigate the prevalence of psychological problems in different healthcare workers(ie,physicians,medical residents,nurses,technicians and public health professionals)during the COVID-19 pandemic in China and explore factors that are associated with the onset of psychological problems in this population during this public health crisis.Methods A cross-sectional,web-based survey was conducted in February 2020 among healthcare workers during the COVID-19 pandemic.Psychological problems were assessed using the Generalized Anxiety Disorder Scale,Patient Health Questionnaire and Insomnia Severity Index.Logistic regression analyses were used to explore the factors that were associated with psychological problems.Results The prevalence of symptoms of anxiety,depression,insomnia and the overall psychological problems in healthcare workers during the COVID-19 pandemic in China was 46.04%,44.37%,28.75%and 56.59%,respectively.The prevalence of the overall psychological problems in physicians,medical residents,nurses,technicians and public health professionals was 60.35%,50.82%,62.02%,57.54%and 62.40%,respectively.Compared with healthcare workers who did not participate in front-line work,front-line healthcare workers had a higher risk of anxiety,insomnia and overall psychological problems.In addition,attention to negative or neutral information about the pandemic,receiving negative feedback from families and friends who joined front-line work,and unwillingness to join front-line work if given a free choice were three major factors for these psychological problems.Conclusions Psychological problems are pervasive among healthcare workers during the COVID-19 pandemic.Receiving negative information and participating in front-line work appear to be.important risk factors for psychological problems.The psychological health of different healthcare workers should be protected during the COVID-19 pandemic with timely interventions and proper information feedback. | Jianyu Que Le Shi Jiahui Deng Jiajia Liu Li Zhang Suying Wu Yimiao Gong Weizhen Huang Kai Yuan Wei Yan Yankun Sun Maosheng Ran Yanping Bao Lin Lu | 2020 | General Psychiatry2020，33，3： | 8 |
| 3 | IL-17A-dependent gut microbiota is essential for regulating diet-induced disorders in mice显示文摘The gut microbiota plays a key role in obesity and related metabolic disorders, and multiple factors including diet, host genotype, and age regulate it. Many studies have examined the contribution of extrinsic factors to the regulation of the gut microbiota, but the importance of the host genetic constitution cannot be ignored. Interleukin 17A(IL-17A), a pro-inflammatory cytokine, is important in the defense against infection and diseases. Here, we investigated the association among IL-17, a high-fat diet(HFD), and the gut microbiota. Mice deficient in IL-17A were resistant to diet-induced obesity and related diseases. Compared with the Ⅱ-17^(-/-)mice, wild-type(WT) mice challenged with HFD showed obvious weight fluctuations, such as those seen in type 2 diabetes, and hematological changes similar to those associated with metabolic syndrome. However, housing WT mice and Ⅱ-17a^(-/-)mice together significantly alleviated these symptoms in the WT mice. A metagenomic analysis of the mouse feces indicated that the microbial community compositions of these two groups differed before HFD feeding. The HFD mediated shifts in the gut microbial compositions, which were associated with the mouse phenotypes.We also identified potentially beneficial and harmful species present during this period, and drew networks of the most abundant species. A functional analysis indicated pathway changes in the WT and Ⅱ-17a^(-/-)mice when fed the HFD. Collectively, these data underscore the importance of the host factor IL-17 A in shaping and regulating the gut microbiota, which conversely, influences the host health. | Yujing Bi Chunxiao Li Lin Liu Jiyuan Zhou Zhengchao Li Huimin Deng Chunyan Wu Yanping Han Yajun Song Yafang Tan Xiaoyi Wang Zongmin Du Yujun Cui Yanfeng Yan Fachao Zhi Guangwei Liu Nan Qin Heping Zhang Ruifu Yang | 2017 | Science Bulletin2017，62，15： | 5 |
| 4 | Higher Order Triangular Mixed Finite Element Methods for Semilinear Quadratic Optimal Control Problems显示文摘In this paper,we investigate a priori error estimates for the quadratic optimal control problems governed by semilinear elliptic partial differential equations using higher order triangular mixed finite element methods.The state and the co-state are approximated by the order k Raviart-Thomas mixed finite element spaces and the control is approximated by piecewise polynomials of order k(k≥0).A priori error estimates for the mixed finite element approximation of semilinear control problems are obtained.Finally,we present some numerical examples which confirm our theoretical results. | Kang Deng Yanping Chen Zuliang Lu | 2011 | Numerical Mathematics(Theory,Methods and Applications)2011，4，2： | 4 |
| 5 | Effects of confined longitudinal and interface optical phonons on excitons in an asymmetric quantum well显示文摘The interaction between exciton and confined longitudinal optical (LO) phonons, interface optical (IO) phonons in an asymmetric Ga 1 x Al x As/GaAs/Ga 0.7 Al 0.3 As square quantum well is investigated. By applying the LLP-like transformation and variational approach, the numerical results are obtained as functions of the well width and asymmetric-degree of well. The exciton-optical phonons interaction-energy has a minimum value with the increase of the well width. It is demonstrated that the LO-phonon energy-contribution increases while the IO-phonon contribution decreases as the well width increases gradually The energy-contribution of LO-phonon in symmetric and asymmetric square quantum well does not have too much difference but the IO-phonon contribution varies apparently. The exciton binding-energy monotonically decreases with the increase of the well width and is proportional to the left-barrier height. | DENG YanPing TIAN Qiang | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，9： | 2 |
| 6 | A durable 4-1BB-based CD19 CAR-T cell for treatment of relapsed or refractory non-Hodgkin lymphoma显示文摘Objective:Previous studies reported that 4-1BB-based CD19 chimeric antigen receptor(CAR)-T cells were more beneficial for the clinical outcomes than CD28-based CAR-T cells,especially the lower incidence rate of severe adverse events.However,the median progression-free survival(mPFS)of 4-1BB-based product Kymriah was shorter than that of CD28-based Yescarta(2.9 months vs.5.9 months),suggesting that Kymriah was limited in the long-term efficacy.Thus,a safe and durable 4-1BB-based CD19 CAR-T needs to be developed.Methods:We designed a CD19-targeted CAR-T(named as IM19)which consisted of an FMC63 scFv,4-1BB and CD3ζintracellular domain and was manufactured into a memory T-enriched formulation.A phase I/II clinical trial was launched to evaluate the clinical outcomes of IM19 in relapsed or refractory(r/r)B cell non-Hodgkin lymphoma(B-NHL).Dose-escalation investigation(at a dose of 5×10^(5)/kg,1×10^(6)/kg and 3×106/kg)was performed in 22 r/r B-NHL patients.All patients received a single infusion of IM19 after 3-day conditional regimen.Results:At month 3,the overall response rate(ORR)was 59.1%,the complete response rate(CRR)was 50.0%.The mPFS was 6 months and the 1-year overall survival rate was 77.8%.Cytokine release syndrome(CRS)occurred in 13 patients(59.1%),with 54.5%of grade 1−2 CRS.Only one patient(4.5%)experienced grade 3 CRS and grade 3 neurotoxicity.Conclusions:These results demonstrated the safety and durable efficacy of a 4-1BB-based CD19 CAR-T,IM19,which is promising for further development and clinical investigation. | Zhitao Ying Ting He Shanzhao Jin Xiaopei Wang Wen Zheng Ningjing Lin Meifeng Tu Yan Xie Lingyan Ping Weiping Liu Lijuan Deng Yanping Ding Xuelian Hu Bing Bu Xin’an Lu Yuqin Song Jun Zhu | 2022 | Chinese Journal of Cancer Research2022，34，1： | 2 |
| 7 | Thiolated nano- structured lipid carriers as a potential ocular drug delivery sys- tem for cyclosporine A: Improving in vivo ocular distribution 显示文摘 | Shen Jie Deng Yanping Jin Xuefeng | 2010 | Int JPharm2010，402，12： | 1 |
| 8 | Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils显示文摘Inhibitory immune receptors set thresholds for immune cell activation,and their deficiency predisposes a person to autoimmune responses.However,the agonists of inhibitory immune receptors remain largely unknown,representing untapped sources of treatments for autoimmune diseases.Here,we show that V-set and transmembrane domain-containing 1(VSTM1)is an inhibitory receptor and that its binding by the competent ligand soluble galectin-1(Gal1)is essential for maintaining neutrophil viability mediated by downregulated reactive oxygen species production.However,in patients with systemic lupus erythematosus(SLE),circulating Gal1 is oxidized and cannot be recognized by VSTM1,leading to increased intracellular reactive oxygen species levels and reduced neutrophil viability.Dysregulated neutrophil function or death contributes significantly to the pathogenesis of SLE by providing danger molecules and autoantigens that drive the production of inflammatory cytokines and the activation of autoreactive lymphocytes.Interestingly,serum levels of glutathione,an antioxidant able to convert oxidized Gal1 to its reduced form,were negatively correlated with SLE disease activity.Taken together,our findings reveal failed inhibitory Gal1/VSTM1 pathway activation in patients with SLE and provide important insights for the development of effective targeted therapies. | Xu Jiang Xinyue Xiao Hao Li Yiyi Gong Min Wang Huaxia Yang Lidan Zhao Ying Jiang Yanping Wei Chongchong Zhao Jin Li Yuling Chen Shan Feng Haiteng Deng Shiliang Ma Yue Xu Yudong Liu George C.Tsokos Minghong Jiang Xuan Zhan | 2023 | Cellular & Molecular Immunology2023，20，11： | 1 |
| 9 | Genome-wide analysis of primary auxin-responsive Aux/IAA gene family in maize (Zea mays. L.)显示文摘 | Yijun Wang Dexiang Deng Yunlong Bian Yanping Lv Qin Xie | 2010 | Molecular Biology Reports2010，，8： | 1 |
| 10 | Prognostic evaluation of Nanog, Oct4, Sox2, PCNA, Ki67 and E-cadherin expression in gastric cancer显示文摘 | Ning Li Wenying Deng Jie Ma Bing Wei Kang Guo Wei Shen Yanping Zhang Suxia Luo | 2015 | Medical Oncology2015，，： | 1 |
| 11 | Human Cytomegalovirus Influences Host circRNA Transcriptions during Productive Infection显示文摘Human cytomegalovirus(HCMV)is a double-strand DNA virus widely infected in human.Circular RNAs(circ RNAs)are non-coding RNAs with most functions of which keep unknown,and the effects of HCMV productive infection on host circ RNA transcriptions remain unclear.In this study,we profiled 283 host circ RNAs that significantly altered by HCMV productive infection in human embryonic lung fibroblasts(HELF)by RNA deep sequencing and bioinformatics analysis.Among these,circ SP100,circ MAP3 K1,circ PLEKHM1,and circ TRIO were validated for their transcriptions and sequences.Furthermore,characteristics of circ SP100 were investigated by RT-q PCR and northern blot.It was implied that circ SP100 was produced from the sense strand of the SP100 gene containing six exons.Kinetics of circ SP100 and SP100 m RNA were significantly different after infection:circ SP100 levels increased gradually along with infection,whereas SP100 m RNA levels increased in the beginning and dropped at 24 h post-infection(hpi).Meanwhile,a total number of 257 proteins,including 10 HCMV encoding proteins,were identified potentially binding to cytoplasmic circ SP100 by RNA antisense purification(RAP)and mass spectrometry.Enrichment analysis showed these proteins were mainly involved in the spliceosome,protein processing,ribosome,and phagosome pathways,suggesting multiple functions of circ SP100 during HCMV infection. | Jingui Deng Yujing Huang Qing Wang Jianming Li Yanping Ma Ying Qi Zhongyang Liu Yibo Li Qiang Ruan | 2021 | Virologica Sinica2021，36，2： | 1 |
| 12 | Awareness Towards Rabies and Exposure Rate and Treatment of Dog-Bite Injuries Among Rural Residents—Guangxi Zhuang Autonomous Region,China,2021显示文摘Summary What is already known about this topic?Although fatal once clinical signs appear,rabies is preventable through three proven,effective interventions including mass dog vaccination,postexposure prophylaxis(PEP),and,though sometimes neglected,awareness of rabies.What is added by this report?The total awareness rate of rabies-related knowledge among rural residents was only 57.9%in Guangxi Zhuang Autonomous Region,one of the provinciallevel administrative divisions(PLADs)with endemic rabies in China. | Mantong Zhu Di Mu Qiulan Chen Ning Chen Yanping Zhang Wenwu Yin Yu Li Yingjie Chen Yidan Deng Xianyan Tang | 2021 | China CDC weekly2021，3，53： | 1 |
| 13 | Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization显示文摘 | Sheryl T. Smith Priyankara Wickramasinghe Andrew Olson Dmitri Loukinov Lan Lin Joy Deng Yanping Xiong John Rux Ravi Sachidanandam Hao Sun Victor Lobanenkov Jumin Zhou | 2009 | Developmental Biology2009，，2： | 1 |
| 14 | Assessing Impacting Factors of Dog Owners’Adoption of Dog Vaccination Against Rabies:A Cross-sectional Survey in Rural Areas—Guangxi Zhuang Autonomous Region,China,2021显示文摘Summary What is already known about this topic?Rabies is fatal while preventable.More than 99%of human rabies cases were caused by dog bites worldwide.Mass dog vaccination could interrupt dogmediated rabies if achieving and maintaining a minimum coverage rate of 70%.What does this report contribute?The results of this study show that roughly 23.7%of households owned dogs in Guangxi Zhuang Autonomous Region. | Ning Chen Qiulan Chen Yanping Zhang Mantong Zhu Wenwu Yin Di Mu Yu Li Yingjie Chen Yidan Deng Xianyan Tang | 2021 | China CDC weekly2021，3，42： | 0 |
| 15 | Development of Rural Tourism Industry under the Background of New Rural Construction : A Case Study of Henghe of Boluo County in Huizhou City显示文摘Henghe Town in Boluo County of Huizhou is taken as the research object for analysis.The research and analysis on the tourism industry in Henghe Town of Boluo County are conducted,and the basic situation of rural tourism construction in Henghe Town is sorted out.The forms of tourism industry in Henghe Town and the problems in rural tourism development are identified,and some targeted suggestions and countermeasures are proposed.It hopes to provide ideas and references for the construction of beautiful rural areas in mountainous areas of Guangdong Province,and theoretical reference and practical significance for the development of rural tourism in mountainous areas of Guangdong Province. | Jialing DENG Yanping ZHONG Xiulian LIN | 2024 | Asian Agricultural Research2024，16，3： | 0 |
| 16 | Advances in air pollution control for key industries in China during the 13th five-year plan显示文摘Industrial development is an essential foundation of the national economy,but the industry is also the largest source of air pollution,of which power plants,iron and steel,building materials,and other industries emit large amounts of pollutants.Therefore,the Chinese government has promulgated a series of stringent emission regulations,and it is against this backdrop that research into air pollution control technologies for key industrial sectors is in full swing.In particular,during the 13th Five-Year Plan,breakthroughs have been made in pollution control technology for key industrial sectors.A multi-pollutant treatment technology system of desulfurization,denitrification,and dust collection,which applies to key industries such as power plants,steel,and building materials,has been developed.High-performance materials for the treatment of different pollutants,such as denitrification catalysts and desulfurization absorbers,were developed.At the same time,multi-pollutant synergistic removal technologies for flue gas in various industries have also become a hot research topic,with important breakthroughs in the synergistic removal of NO_(x),SO_(x),and Hg.Due to the increasingly stringent emission standards and regulations in China,there is still a need to work on the development of multi-pollutant synergistic technologies and further research and development of synergistic abatement technologies for CO_(2) to meet the requirements of ultra-low emissions in industrial sectors. | Xuecheng Wu Yanping Yang Yue Gong Zhiwen Deng Ying Wang Weihong Wu Chenghang Zheng Yongxin Zhang | 2023 | Journal of Environmental Sciences2023，，1： | 0 |
| 17 | Thoughts on the development of low-carbon furniture standards system显示文摘低碳的经济的发展广泛地在标准系统是的 world.Building lowcarbon 家具附近被认出了家具标准化的一个重要内容,它有用支持精力保存,减少碳脚印,然后阻止全球 warming.This 纸分析中国的家具标准的现状,说低碳的家具标准系统的开发的重要性,提出低碳的家具标准 s 的一些 ideason | Liu Fujian the research on furniture standardization, laboratory management and quality test technology in the Guangdong Testing Institute For Product Quality Supervision. Deng Yanping in the National Quality Supervision and Test Center for Furniture(Guangdong Province). | 2011 | China Standardization2011，56，1： | 0 |
| 18 | Correction to:Human Cytomegalovirus Influences Host circRNA Transcriptions during Productive Infection显示文摘The information of affiliation 1 and 3 was incorrect.The information of affiliations should read as given below.Author information 1 Virology Lab,Shengjing Hospital of China Medical University,Shenyang 110004,China 2 Department of Laboratory,Central Hospital Affiliated to Shenyang Medical College,Shenyang 110024,China. | Jingui Deng Yujing Huang Qing Wang Jianming Li Yanping Ma Ying Qi Zhongyang Liu Yibo Li Qiang Ruan | 2021 | Virologica Sinica2021，36，2： | 0 |
| 19 | Nitrogen‐doped tin oxide electron transport layer for stable perovskite solar cells with efficiency over 23%显示文摘Tin oxide has made a major breakthrough in high-efficiency perovskite solar cells(PSCs)as an efficient electron transport layer by the low-temperature chemical bath deposition method.However,tin oxide often contains pernicious defects,resulting in unsatisfactory performance.Herein,we develop high-quality tin oxide films via a nitrogen-doping strategy for high-efficiency and stable planar PSCs.The aligned energy level at the interface of doped SnO_(2)/perovskite,more excellent charge extraction and reduced nonradiative recombination contribute to the enhanced efficiency and stability.Correspondingly,the power conversion efficiency of the devices based on N‐SnO_(2) film increases to 23.41% from 20.55% of the devices based on the pristine SnO_(2).The N-SnO_(2) devices show an outstanding stability retaining 97.8% of the initial efficiency after steady-state output at a maximum power point for 600s under standard AM1.5G continuous illumination without encapsulation,while less than 50% efficiency remains for the devices based on pristine SnO_(2).This simple scalable strategy has shown great promise toward highly efficient and stable PSCs. | Yanping Mo Chao Wang Xuntian Zheng Peng Zhou Jing Li Xinxin Yu Kaizhong Yang Xinyu Deng Hyesung Park Fuzhi Huang Yi‐Bing Cheng | 2022 | Interdisciplinary Materials2022，1，2： | 0 |
| 20 | Causal relationships between chronotype and risk of multiple cancers by using longitudinal data and Mendelian randomization analysis显示文摘Dear Editor,Cancer is the second leading cause of death worldwide,and the cancer situation is becoming more complicated(Zhou et al.,2022).The International Agency for Research on Cancer(IARC)Monographs Working Group classified night shift work as probably carcinogenic(Group 2A)to humans in2019(Ward et al.,2019). | Shanshan Tian Longtao Huangfu Sizhi Ai Junwei Zheng Le Shi Wei Yan Ximei Zhu Qianwen Wang Jiahui Deng Yanping Bao Suhua Chang Lin Lu | 2023 | Science China(Life Sciences)2023，66，10： | 0 |
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