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| 1 | Role of BKCa channels in diabetic vascular complications显示文摘 | Qian Lingling Liu Xiaoyu Wang Ruxing | 2014 | Chinese Medical Journal2014，，9： | 12 |
| 2 | Resveratrol reduces intracellular reactive oxygen species levels by inducing autophagy through the AMPK-mTOR pathway显示文摘Oxidative stress induced by free fatty acid aggravates endothelial injury,which leads to diabeti cardiovascular complications.Reduction of intracellular oxidative stress may attenuate these pathogeni processes.The dietary polyphenol resveratrol reportedly exerts potential protective effects against endothelia injury.This study determined whether resveratrol can reduce the palmitic acid (PA)-induced generation o reactive oxygen species (ROS)and further explored the underlying molecular mechanisms.We found tha resveratrol significantly reduced the PA-induced endothelial ROS levels in human aortic endothelial cells Resveratrol also induced endothelial cell autophagy,which mediated the effect of resveratrol on ROS reduction Resveratrol stimulated autophagy via the AMP-activated protein kinase (AMPK)-mTOR pathway.Taketogether,these data suggest that resveratrol prevents PA-induced intracellular ROS by autophagy regulation via the AMPK-mTOR pathway.Thus,the induction of autophagy by resveratrol may provide a novel therapeuti candidate for cardioprotection in metabolic syndrome. | Jun Song Yeping Huang Wenjian Zheng Jing Yan Min Cheng Ruxing Zhao Li Chen Cheng Hu Weiping Jia | 2018 | Frontiers of Medicine2018，12，6： | 7 |
| 3 | Triglycerides and ratio of triglycerides to high-density lipoprotein cholesterol are better than liver enzymes to identify insulin resistance in urban middle-aged and older non-obese Chinese without diabetes显示文摘 | Sun Yu Li Wenjuan Hou Xinguo Wang Chuan Li Chengqiao Zhang Xiuping Yang Weifang Ma Zeqiang Wang Weiqing Ning Guang Zheng Huizhen Ma Aixia Song Jun Lin Peng Liang Kai Liu Fuqiang Gong Lei Wang Meijian Xiao Juan Yan Fei Yang Junpeng Wang Lingshu Tian Meng Liu Jidong Zhao Ruxing Zhu Ping Chen Li | 2014 | Chinese Medical Journal2014，，10： | 7 |
| 4 | AEG-1 expression correlates with CD133 and PPP6c levels in human glioma tissues显示文摘Astrocyte elevated gene-1(AEG-1) is associated with tumor genesis and progression in a variety of human cancers.This study aimed to explore the significance of AEG-l in glioma and investigate whether it correlated with radioresistance of glioma cells.Immunohistochemical staining showed that the intensity of AEG-l,CD133 and PPP6 c protein expression in glioma tissues increased significantly,mainly in the cytoplasm.The expression rate of AEG-l,CD133 and PPP6c were 85.9%(67/78),60.3%(47/78) and 65.8%(51/78),respectively.AEG-l expression was correlated with age(r=0.227,P=0.045),clinical stage(r=0.491,P<0.001) and clinical grade(r=0.450,P<0.001).No correlation was found between AEG-l expression and other clinicopathologic parameters(P>0.05).The expression of AEG-1 was positively correlated with the expression of CD133(r=0.240,P = 0.035) and PPP6c(r= 0.250,P = 0.027).In addition,retrieved data on TCGA implied co-occurrence of genomic alterations of AEG-l and PPP6 c in glioblastoma.Our findings indicate that AEG-l is positively correlated with CD133 and AEG-l expression.It may play an important role in the progression of glioma and may serve as potential novel marker of chemoresistance and radioresistance. | Jia Guo Xin Chen Ruxing Xi Yuwei Chang Xuanwei Zhang Xiaozhi Zhang | 2014 | The Journal of Biomedical Research2014，28，5： | 3 |
| 5 | Low dielectric loss and enhanced tunable properties of Cr-doped barium strontium titanate solid solution显示文摘 | LI Ruxing CHENG Jinrong MENG Zhongyan | 2006 | J Mater Sci: Mater Electron2006，17，8： | 1 |
| 6 | Adenovirus Structure显示文摘 | Rux J J Burnett RM | 2004 | Human Gene Therapy2004，15，12： | 1 |
| 7 | Novel diagnostic assays for heparin-induced thrombocytopenia显示文摘 | Cuker A Rux AH Hinds JL | 2013 | Blood2013，121，18： | 1 |
| 8 | Adenovirus structure 显示文摘 | Rux J J Burnett R M | 2004 | Hum gene ther2004，15，12： | 1 |
| 9 | Disulfide bond structure determination and biochemical analysis of glycoprotein C from herpes simplex virus显示文摘 | Rux A Moore W Lambris J | 1996 | J Virol1996，70，8： | 1 |
| 10 | Novel diagnostic assays for heparin-induced thrombocytopenia显示文摘 | Cuker A Rux AH Hinds JL | 2013 | Blood2013，121，18： | 1 |
| 11 | The major neutralizing antigenic site on herpes simplex virus glycoprotein D overlaps a receptor-binding domain显示文摘 | Whitbeck J C Muggeridge M I Rux A H | 1999 | J Virol1999，73，： | 1 |
| 12 | Endothelial expression of E-selectin is induced by the platelet-specifie chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner显示文摘 | Yu G Rux AH Ma P | 2005 | Blood JT2005，105，9： | 1 |
| 13 | Gene specific siRNA selector显示文摘 | Gu Q Rux JJ | 2004 | Bioinformatics2004，20，3： | 1 |
| 14 | Type-specific epitope locations revealed by X-ray crystallographic study of adenovirus type 5 hexon 显示文摘 | Rux JJ Burnett RM | 2000 | Mol Ther2000，1，1： | 1 |
| 15 | Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methods 显示文摘 | Rux JJ Kuser PR Burnett RM | 2003 | J Virol2003，77，17： | 1 |
| 16 | The first immunoglobulin- like domain of HveC is sufficient to bind herpes simplex virus gD with full affinity,while the third domain is involved in oligomerization of HveC显示文摘 | Krummenacher C Rux AH Whitbeck JC | 1999 | virol1999，73，： | 1 |
| 17 | Glycoprotein D homologs in herpes simplex virus type 1,pseudorabies virus and bovine herpes virus type 1 bind directly to human HveC (nectin-1) with different affinities显示文摘 | Connolly S A Whitbeck J J Rux A H | 2001 | Virology2001，280，： | 1 |
| 18 | The major neutrali- zing antigenic site on herpes simplex virus glycoprotein D overlaps a receptor - binding domain显示文摘 | Whitbeck J C Muggeridge M I Rux A H | 1999 | Journal of Virology1999，73，12： | 1 |
| 19 | Gene specific siRNA selector 显示文摘 | Levenkova N Gu Q Rux JJ | 2004 | Bioinformatics2004，20，3： | 1 |
| 20 | HoxA3 is an apical regulator of haemogenic endothelium显示文摘 | Hartweck L Rux D Caprioli A | | 0，，01： | 1 |
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