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| 1 | Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke:a randomised controlled trial显示文摘Purpose To evaluate the efficacy and safety of Ginkgo biloba extract(GBE)in acute ischaemic stroke and its impact on the recurrence of vascular events.Methods We conducted a multicentre,prospective,randomised,open label,blinded,controlled clinical trial enrollingpatients with an onset of acute stroke within 7 days from five hospitals in China Jiangsu Province.Participants were assigned to the GBE group(450 mg GBE with 100 mg aspirin daily)or the control group(100 mg aspirin daily)for 6 months.The primary outcome was the decline in the Montreal Cognitive Assessment score at 6 months.Secondary outcomes were other neuropsychological tests of cognitive and neurological function,the the incidence of adverse events and vascular events.results 348 patients were enrolled:179 in the GBE group and 169 in the control group.With 18 patients lost to follow-up,the dropout rate was 5.17%.Admission data between two groups were similar,but in the GBE group there was a marked slow down in the decline in the Montreal Cognitive Assessment scores(−2.77±0.21 vs−1.99±0.23,P=0.0116(30 days);−3.34±0.24 vs−2.48±0.26,P=0.0165(90 days);−4.00±0.26 vs−2.71±0.26,P=0.0004(180 days))compared with controls.The National Institutes of Health Stroke Scale scores at 12 and 30 days,the modified Rankin Scale scores for independent rate at 30,90 and 180 days,and the Barthel Index scores at 30,90 and 180 days in the GBE group were significantly improved compared with controls.Improvements were also observedin GBE groups for Mini-Metal State Examination scores of 30,90 and 180 days,Webster's digit symbol test scores at 30 days and Executive Dysfunction Index scores at 30 and 180 days.No significant differences were seen in the incidence of adverse events or vascular events.conclusions We conclude that GBE in combination with aspirin treatment alleviated cognitive and neurological deficits after acute ischaemic stroke without increasing the incidence of vascular events. | Shanshan Li Xinjiang Zhang Qi Fang Junshan Zhou Meijuan Zhang Hui Wang Yan Chen Biyun Xu Yanfeng Wu Lai Qian Yun Xu | 2017 | Stroke & Vascular Neurology2017，2，4： | 25 |
| 2 | Hybrid Material of Graphene and Poly(3,4-ethyldioxythiophene)with High Conductivity,Flexibility,and Transparency显示文摘A novel hybrid material prepared from graphene and poly(3,4-ethyldioxythiophene)(PEDOT)shows excellent transparency,electrical conductivity,and good flexibility,together with high thermal stability and is easily processed in both water and organic solvents.Conductivities of the order of 0.2 S/cm and light transmittance of greater than 80%in the 4001800 nm wavelength range were observed for fi lms with thickness of tens of nm.Practical applications in a variety of optoelectronic devices are thus expected for this transparent and flexible conducting graphene-based hybrid material。 | Yanfei Xu Yan Wang Jiajie Liang Yi Huang Yanfeng Ma Xiangjian Wan Yongsheng Chen | 2009 | Nano Research2009，2，4： | 23 |
| 3 | Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC)is a poor-prognosis cancer type with limited understanding of its molecular etiology.Using 508 ESCC genomes,we identified five novel significantly mutated genes and uncovered mutational signature clusters associated with metastasis and patients’outcomes.Several functional assays implicated that NFE2L2 may act as a tumor suppressor in ESCC and that mutations in NFE2L2 probably impaired its tumor-suppressive function,or even conferred oncogenic activities.Additionally,we found that the NFE2L2 mutations were significantly associated with worse prognosis of ESCC.We also identified potential noncoding driver mutations including hotspot mutations in the promoter region of SLC35E2 that were correlated with worse survival.Approximately 5.9%and 15.2%of patients had high tumor mutation burden or actionable mutations,respectively,and may benefit from immunotherapy or targeted therapies.We found clinically relevant coding and noncoding genomic alterations and revealed three major subtypes that robustly predicted patients’outcomes.Collectively,we report the largest dataset of genomic profiling of ESCC useful for developing ESCC-specific biomarkers for diagnosis and treatment. | Yongping Cui Hongyan Chen Ruibin Xi Heyang Cui Yahui Zhao Enwei Xu Ting Yan Xiaomei Lu Furong Huang Pengzhou Kong Yang Li Xiaolin Zhu Jiawei Wang Wenjie Zhu Jie Wang Yanchun Ma Yong Zhou Shiping Guo Ling Zhang Yiqian Liu Bin Wang Yanfeng Xi Ruifang Sun Xiao Yu Yuanfang Zhai Fang Wang Jian Yang Bin Yang Caixia Cheng Jing Liu Bin Song Hongyi Li Yi Wang Yingchun Zhang Xiaolong Cheng Qimin Zhan Yanhong Li Zhihua Liu-Show | 2020 | Cell Research2020，30，10： | 19 |
| 4 | Hydroisomerization performance of platinum supported on ZSM-22/ZSM-23 intergrowth zeolite catalyst显示文摘Hydroisomerization catalysts Pt/ZSM-22,Pt/ZSM-23,and Pt/ZSM-22/ZSM-23 were prepared by supporting Pt on ZSM-22,ZSM-23,and intergrowth zeolite ZSM-22/ZSM-23,respectively.The typical physicochemical properties of these catalysts were characterized by X-Ray Diffraction(XRD),N2 absorption-desorption,Pyridine-Fourier Transform Infrared(Py-FTIR),Transmission Electron Microscopy(TEM),X-Ray Fluorescence(XRF),Scanning Electron Microscopy(SEM) and NH3-Temperature Programmed Desorption(NH3-TPD),and the performance of these catalysts in n-dodecane hydroisomerization was evaluated in a continuous down-flow fixed bed with a stainless steel tubular reactor.The characterization results indicated that the intergrowth zeolite ZSM-22/ZSM-23 possessed the dual structure of ZSM-22 and ZSM-23,and the catalyst Pt/ZSM-22/ZSM-23 had similar pores and weak acidity to Pt/ZSM-22 and Pt/ZSM-23 catalysts.Moreover,Pt/ZSM-22/ZSM-23 catalyst showed a high selectivity in hydroisomerization of long chain n-alkanes to mono-branched isomers.The evaluation results for n-dodecane hydroisomerization indicated that the activity of Pt/ZSM-22/ZSM-23 was the lowest,while the hydroisomerization selectivity was the highest among the three catalysts.The maximum yield of i-dodecane product was 68.3% over Pt/ZSM-22/ZSM-23 at 320 oC. | Chi Kebin Zhao Zhen Tian Zhijian Hu Sheng Yan Lijun Li Tianshu Wang Bingchun Meng Xiangbin Gao Shanbin Tan Mingwei Liu Yanfeng | 2013 | Petroleum Science2013，10，2： | 8 |
| 5 | Water-use efficiency in response to simulated increasing precipitation in a temperate desert ecosystem of Xinjiang, China显示文摘Water-use efficiency(WUE) is a key plant functional trait that plays a central role in the global cycles of water and carbon. Although increasing precipitation may cause vegetation changes, few studies have explored the linkage between alteration in vegetation and WUE. Here, we analyzed the responses of leaf WUE, ecosystem carbon and water exchanges, ecosystem WUE, and plant community composition changes under normal conditions and also under extra 15% or 30% increases in annual precipitation in a temperate desert ecosystem of Xinjiang, China. We found that leaf WUE and ecosystem WUE showed inconsistent responses to increasing precipitation. Leaf WUE consistently decreased as precipitation increased. By contrast, the responses of the ecosystem WUE to increasing precipitation are different in different precipitation regimes: increasing by 33.9% in the wet year(i.e., the normal precipitation years)and decreasing by 4.1% in the dry year when the precipitation was about 30% less than that in the wet year.We systematically assessed the herbaceous community dynamics, community composition, and vegetation coverage to explain the responses of ecosystem WUE, and found that the between-year discrepancy in ecosystem WUE was consistent with the extent to which plant biomass was stimulated by the increase in precipitation. Although there was no change in the relative significance of ephemerals in the plant community, its greater overall plant biomass drove an increased ecosystem WUE under the conditions of increasing precipitation in 2011. However, the slight increase in plant biomass exerted no significant effect on ecosystem WUE in 2012. Our findings suggest that an alteration in the dominant species in this plant community can induce a shift in the carbon-and water-based economics of desert ecosystems. | HUANG Gang LI Yan MU Xiaohan ZHAO Hongmei CAO Yanfeng | 2017 | Journal of Arid Land2017，9，6： | 7 |
| 6 | IL-17A-dependent gut microbiota is essential for regulating diet-induced disorders in mice显示文摘The gut microbiota plays a key role in obesity and related metabolic disorders, and multiple factors including diet, host genotype, and age regulate it. Many studies have examined the contribution of extrinsic factors to the regulation of the gut microbiota, but the importance of the host genetic constitution cannot be ignored. Interleukin 17A(IL-17A), a pro-inflammatory cytokine, is important in the defense against infection and diseases. Here, we investigated the association among IL-17, a high-fat diet(HFD), and the gut microbiota. Mice deficient in IL-17A were resistant to diet-induced obesity and related diseases. Compared with the Ⅱ-17^(-/-)mice, wild-type(WT) mice challenged with HFD showed obvious weight fluctuations, such as those seen in type 2 diabetes, and hematological changes similar to those associated with metabolic syndrome. However, housing WT mice and Ⅱ-17a^(-/-)mice together significantly alleviated these symptoms in the WT mice. A metagenomic analysis of the mouse feces indicated that the microbial community compositions of these two groups differed before HFD feeding. The HFD mediated shifts in the gut microbial compositions, which were associated with the mouse phenotypes.We also identified potentially beneficial and harmful species present during this period, and drew networks of the most abundant species. A functional analysis indicated pathway changes in the WT and Ⅱ-17a^(-/-)mice when fed the HFD. Collectively, these data underscore the importance of the host factor IL-17 A in shaping and regulating the gut microbiota, which conversely, influences the host health. | Yujing Bi Chunxiao Li Lin Liu Jiyuan Zhou Zhengchao Li Huimin Deng Chunyan Wu Yanping Han Yajun Song Yafang Tan Xiaoyi Wang Zongmin Du Yujun Cui Yanfeng Yan Fachao Zhi Guangwei Liu Nan Qin Heping Zhang Ruifu Yang | 2017 | Science Bulletin2017，62，15： | 5 |
| 7 | Exploring Seasonal and Circadian Rhythms in Structural Traits of Field Maize from LiDAR Time Series显示文摘Plant growth rhythm in structural traits is important for better understanding plant response to the ever-changing environment.Terrestrial laser scanning(TLS)is a well-suited tool to study structural rhythm under field conditions.Recent studies have used TLS to describe the structural rhythm of trees,but no consistent patterns have been drawn.Meanwhile,whether TLS can capture structural rhythm in crops is unclear.Here,we aim to explore the seasonal and circadian rhythms in maize structural traits at both the plant and leaf levels from time-series TLS.The seasonal rhythm was studied using TLS data collected at four key growth periods,including jointing,bell-mouthed,heading,and maturity periods.Circadian rhythms were explored by using TLS data acquired around every 2 hours in a whole day under standard and cold stress conditions.Results showed that TLS can quantify the seasonal and circadian rhythm in structural traits at both plant and leaf levels.(1)Leaf inclination angle decreased significantly between the jointing stage and bell-mouthed stage.Leaf azimuth was stable after the jointing stage.(2)Some individual-level structural rhythms(e.g.,azimuth and projected leaf area/PLA)were consistent with leaf-level structural rhythms.(3)The circadian rhythms of some traits(e.g.,PLA)were not consistent under standard and cold stress conditions.(4)Environmental factors showed better correlations with leaf traits under cold stress than standard conditions.Temperature was the most important factor that significantly correlated with all leaf traits except leaf azimuth.This study highlights the potential of time-series TLS in studying outdoor agricultural chronobiology. | Shichao Jin Yanjun Su Yongguang Zhang Shilin Song Qing Li Zhonghua Liu Qin Ma Yan Ge LingLi Liu Yanfeng Ding Frédéric Baret Qinghua Guo | 2021 | Plant Phenomics2021，3，1： | 5 |
| 8 | The formation of perovskite multiple quantum well structures for high performance light-emitting diodes显示文摘Recent works showed that high efficient perovskite light-emitting diodes can be achieved from solution-processed,self-organized multiple quantum wells(MQWs)with an energy cascade.We investigate how the mixing of QWs with different band gaps can affect the perovskite LED device performance.We find that the annealing process can significantly affect the constitution of the MQWs films,where the dominant phase can evolve from large band gap QWs to small band gap QWs.The optimal constitution for LED application lies in a transition point of small-n QWs dominant phase to large-n QWs dominant phase,when the MQW film presents highest photoluminescence while still remains uniform film morphology. | Yan Sun Li Zhang Nana Wang Shuting Zhang Yu Cao Yanfeng Miao Mengmeng Xu Hao Zhang Hai Li Chang Yi Jianpu Wang Wei Huang | 2018 | npj Flexible Electronics2018，2，1： | 4 |
| 9 | Efficient induction of a Her2-specific anti-tumor response by dendritic cells pulsed with a Hsp70L1–Her2_(341–456) fusion protein显示文摘Heat shock proteins(HSPs)have been shown to interact with antigen-presenting cells(APCs),especially dendritic cells(DCs).HSPs act as potent adjuvants,inducing a Th1 response,as well as antigen-specific CD8^(+) cytotoxic T lymphocytes(CTL)via cross-presentation.Our previous work has demonstrated that Hsp70-like protein 1(Hsp70L1),a new member of the Hsp70 subfamily,can act as a powerful Th1 adjuvant in a DC-based vaccine.Here we report the efficient induction of tumor antigen-specific T cell immune response by DCs pulsed with recombinant fusion protein of Hsp70L1 and Her2_(341–456),the latter of which is a fragment of Her2/neu(Her2)containing E75(a HLA-A2 restricted CTL epitope).The fusion protein Hsp70L1–Her2_(341–456) promotes the maturation of DCs and activates them to produce cytokines,such as IL-12 and TNF-a,and chemokines,such as MIP-1a,MIP-1b and RANTES.Taken together,these results indicate that the adjuvant activity of Hsp70L1 is maintained in the fusion protein.Her2-specific HLA-A2.1-restricted CD8^(+) CTLs can be generated efficiently either from the Peripheral blood lymphocytes(PBL)of healthy donors or from the splenocytes of immunized HLA-A2.1/K^(b) transgenic mice by in vitro stimulation or immunization with DCs pulsed with the Hsp70L1–Her2_(341–456) fusion protein.This results in more potent target cell killing in an antigen-specific and HLA-A2.1-restricted manner.Adoptive transfer of splenocytes from transgenic mice immunized with Hsp70L1–Her2_(341–456)-pulsed DCs can markedly inhibit tumor growth and prolong the survival of nude mice with Her2^(+)/HLA-A2.1^(+) human carcinomas.These results suggest that Hsp70L1–Her2_(341–456)-pulsed DCs could be a new therapeutic vaccine for patients with Her2^(+) cancer. | Qiang Fu Yanfeng Wu Fang Yan Ning Wang Wenying Wang Xuetao Cao Yajie Wang Tao Wan | 2011 | Cellular & Molecular Immunology2011，8，5： | 3 |
| 10 | Long-term straw incorporation increases rice yield stability under high fertilization level conditions in the rice–wheat system显示文摘Straw incorporation is a global common practice to improve soil fertility and rice yield.However,the effect of straw incorporation on rice yield stability is still unknown,especially under high fertilization level conditions.Here,we reported the effect of straw returning on rice yield and yield stability under high fertilization levels in the rice–wheat system over nine years.The results showed that straw incorporation did not significantly affect the average rice yield of nine years.Straw incorporation reduced the coefficient of variation of rice yield by 25.8%and increased the sustainable yield index by 8.2%.The rice yield positively correlated with mean photosynthetically active radiation (PAR) of rice growth season and the effects of straw incorporation on rice yield depended on the PAR.Straw incorporation increased the rice yield by 5.4%in the low PAR years,whereas it did not affect the rice yield in the high PAR years.Long-term straw incorporation lowered soil bulk density but improved the soil organic matter,total N,available N,available P,and available K more strongly than straw removal.Our findings suggest that straw incorporation can increase rice yield stability through improving the resistance of rice plant growth to low PAR. | Jianwei Zhang Weiwei Li Yan Zhou Yanfeng Ding Lei Xu Yu Jiang Ganghua Li | 2021 | The Crop Journal2021，9，5： | 3 |
| 11 | Modeling the effects of plastic film mulching on irrigated maize yield and water use efficiency in sub-humid Northeast China显示文摘In sub-humid Northeast China,plastic film mulching(PFM)is increasingly used with drip irrigation system in maize(Zea mays L.)to cope with seasonal droughts and low temperatures during seedling stage.Although there were several studies showing the benefits of PFM on maize production in the region,quantification of the effects of PFM in sub-humid Northeast China are still lacking.Hybrid-Maize model has a special version that can not only simulate the effects of PFM on reduction of soil evaporation and rise of topsoil temperature,but also simulate the effects of PFM on crop development and other physiological processes.This paper reports how to verify the Hybrid-Maize model against observations and then applying the model to quantify effects of PFM on grain yield and water use efficiency(WUE)under irrigated scenarios.The Hybrid-Maize model was added the heating effects of PFM on rising surface-soil temperature and promoting subsequent crop development by establishing equations between surface-soil temperature and air temperature before V6 stage.A 3-year field experiment including maize growth and yield data measured at a drip-irrigated field in Heilongjiang Province was used to serve the model calibration.The simulated results indicated that the Hybrid-Maize model performed well in simulation of seasonal soil water storage and in-season aboveground dry matter in three years,but overestimated the leaf area index(LAI)for both treatments and underestimated the final aboveground dry matter at maturity for mulched treatments.Although the Hybrid-Maize model overestimated the grain yield and WUE,it did still reflect the effects of PFM on increasing grain yield and WUE during the three growing seasons.The average simulated grain yield and WUE for mulched treatments were 8%and 13%greater compared to non-mulched treatments using 30 years weather data,which were in agreement with observations that average grain yield and WUE was 11%and 14%increased by PFM,respectively.For evapotranspiration(ET),the average simulated ET for mulched treatments was 22 mm less than non-mulched treatments mainly due to less soil evaporation.For simulated irrigation requirements,at most 69 mm of irrigation water could be saved by PFM.In conclusion,PFM with drip irrigation could improve irrigated maize production in sub-humid Northeast China. | Liu Yang Yang Haishun Li Yanfeng Yan Haijun Li Jiusheng | 2017 | International Journal of Agricultural and Biological Engineering2017，10，5： | 2 |
| 12 | Biophotonic Activity and Transmission Mediated by Mutual Actions of Neurotransmitters are Involved in the Origin and Altered States of Consciousness显示文摘Dear Editor Despite remarkable advances in our understanding of brain functions,the neural substrates and correlates of consciousness remain unclear[1].It has been argued that classical physics is intrinsically incapable of explaining the holistic aspects of consciousness,especially its | Weitai Chai Zhengrong Han Zhuo Wang Zehua Li Fangyan Xiao Yan Sun Yanfeng Dai Rendong Tang Jiapei Dai | 2018 | Neuroscience Bulletin2018，34，3： | 2 |
| 13 | Transcriptomic Response to Yersinia pestis:RIG-I Like Receptor Signaling Response Is Detrimental to the Host against Plague显示文摘Bacterial pathogens have evolved various mechanisms to modulate host immune responses for successful infection.In this study,RNAsequencing technology was used to analyze the responses of human monocytes THP1 to Yersinia pestis infection.Over 6000 genes were differentially expressed over the 12 h infection.Kinetic responses of pathogen recognition receptor signaling pathways,apoptosis,antigen processing,and presentation pathway and coagulation system were analyzed in detail.Among them,RIG-I-like receptor(RLR) signaling pathway,which was established for antiviral defense,was significantly affected.Mice lacking MAVS,the adaptor of the RLR signahng pathway,were less sensitive to infection and exhibited lower IFN-P production,higher Thl-type cytokines IFN-y and IL-12 production,and lower Th2-type cytokines EL-4 and IL-13 production in the serum compared with wild-type mice.Moreover,infection of pathogenic bacteria other than Y.pestis also altered the expression of the RLR pathway,suggesting that the response of RLR pathway to bacterial infection is a universal mechanism. | Zongmin Du Huiying Yang Yafang Tan Guang Tian Qingwen Zhang Yujun Cui Yanfeng Yan Xiaohong Wu Zuyun Chen Shiyang Cao Yujing Bi Yanping Han Xiaoyi Wang Yajun Song Ruifu Yan | 2014 | Journal of Genetics and Genomics2014，41，7： | 2 |
| 14 | Electrical and mechanical performance of graphene sheets exposed to oxidative environments显示文摘当暴露了到不同媒介时, Graphene 涂层被显示了保护内在的材料免受氧化的伤害。然而,在在房间温度的空中的 graphene 的使钝化的性质,对应于许多电子设备的操作条件,仍然保持不清楚。在这个工作,我们为时间的长时期在房间温度在空中分析 graphene/Cu 样品的氧化动力学(从 1 天到 113 天)用扫描电子显微镜学,传导性的原子力量显微镜学和钻电子显微镜学,并且我们把结果与那些为在 H2O2 对待的类似的样品获得了作比较。我们不同于暴露于 H2O2,在 graphene 领域边界的氧的累积在演变在的 graphene 表观察那一很控制了并且进步方法,在空中的 graphene 的本地氧化以一种混乱方式发生。在两个盒子中,在 graphene 领域边界形成的氧化物小丘能宣传到领域直到到达限制宽度和高度。我们的结果证明沿着域边界的内在的材料的本地氧化能戏剧性地减少粗糙,传导性,机械抵抗和 graphene 表的摩擦特征,哪个还原剂整个设备的性能。 | Mario Lanza Yan Wang Teng Gao Albin Bayerl Marc Porti Montserrat Nafria Yangbo Zhou Guangyin Jing Yanfeng Zhang Zhongfan Liu Dapeng Yu Huiling Duan | 2013 | Nano Research2013，6，7： | 2 |
| 15 | Highly safe and ionothermal synthesis of Ti3C2 MXene with expanded interlayer spacing for enhanced lithium storage显示文摘MXene is a rising star of two-dimensional(2D)materials for energy relative applications,however,the traditional synthesis of MXene etched by hazard HF acid or LiF+HCl mixed solution is highly dangerous with the risk of splashing or pouring liquid solutions.In this work,we developed a water-free ionothermal synthesis of 2D Ti3C2 MXene via etching pristine Ti3AlC2 MAX in low-cost choline chloride and oxalic acid based deep eutectic solvents(DES)with the presence of NH4F,thus it was highly safe and convenient to operate solid precursor and product materials at room temperature.Benefited from the low vapor pressure and solvating properties of DES,the prepared Ti3C2(denoted as DES-Ti3C2)possessed a high purity up to 98% compared with 95% for HF etched Ti3C2(denoted as HF-Ti3C2).Notably,an expanded interlayer spacing of 1.35 nm could be achieved due to the intercalation of choline cations in DES-Ti3C2,larger than that of HF-Ti3C2(0.98 nm).As a result,the DES-Ti3C2 anodes exhibited enhanced lithium storage performance,such as high reversible capacity of 208 m Ah g-1at 0.5 A g-1,and long cycle life over 400 times,outperforming most reported pure MXene anodes.The ionothermal synthesis of MXene developed here may pave a new way to safely prepare other MXene for various energy relating applications. | Junbiao Wu Yu Wang Yaopeng Zhang Hao Meng Yan Xu Yide Han Zhuopeng Wang Yanfeng Dong Xia Zhang | 2020 | Journal of Energy Chemistry2020，29，8： | 1 |
| 16 | Extended MLST-based population genetics and phylogeny of Vibrio parahaemolyticus with high levels of recombination显示文摘 | YAN Yanfeng CUI Yujun HAN Haihong | 2011 | International Journal of Food Microbiology2011，145，1： | 1 |
| 17 | Integrated Protraction System Design for Shipboard Power System显示文摘 | Gong Yanfeng Huang Yan Schulz N N | 2008 | IEEE Transactions on Industry Applications2008，44，6： | 1 |
| 18 | Y ersinia protein kinase A phosphorylates vasodilator‐stimulated phosphoprotein to modify the host cytoskeleton显示文摘 | Yuehua Ke Yafang Tan Na Wei Fen Yang Huiying Yang Shiyang Cao Xiaohui Wang Jian Wang Yanping Han Yujing Bi Yujun Cui Yanfeng Yan Yajun Song Xiaoming Yang Zongmin Du Ruifu Yang | 2015 | Cell Microbiol2015，，： | 1 |
| 19 | The Establishment and Application of Mobile Electronic Surveillance System for Infectious Diseases with the Help of China—Sierra Leone,2016-Present显示文摘Introduction:Infectious disease surveillance has long been a challenge for low-income countries like Sierra Leone.Traditional approaches based on paper and Short Message Service(SMS)were subject to severe delays in obtaining,transmitting,and analyzing information.Methods:During the China aid operation for fighting Ebola since the end of 2014,a mobile electronic surveillance system for infectious diseases(MESSID)was developed in collaboration with the Republic of Sierra Leone Armed Forces(RSLAF),which comprised an Android-based reporting system and a complementary web-based program designed by Active Server Page.NET(ASP.NET)with the main functions including surveillance,real-time reporting,and risk assessment of infectious diseases.Results:MESSID was successfully registered in June 2016 and had been used by all medical and health institutions in RSLAF.From June 1,2016 to July 5,2021,34,419 cases were diagnosed with 47 infectious diseases of 5 categories,with a total of 42 clinical symptoms.Compared to traditional approaches based on paper and SMS,the MESSID showed flexibility,high efficiency,convenience,and acceptability.Discussion:MESSID is an accessible tool for surveillance of infectious diseases in Sierra Leone and possibly in other African countries with similar needs,capable of improving timeliness of disease reporting,thus rendering a timely outbreak detection and response. | Guangyu Zhao Haorong Chen Yanfeng Yan Jiafu Jiang Lei Lin Baogui Jiang Foday Sahr Stephen Sevalie Qiang Xu Jinjin Chen Henry Saidu Bangura Kandeh Bassie Kargbo Yajun Song Wei Liu Liqun Fang Yansong Sun | 2021 | China CDC weekly2021，3，36： | 1 |
| 20 | Study on plastic behaviours of CuNi10Fe1Mn alloy tubes under cast-roll process显示文摘 | Yabo Fu Zhiming Yan Tingju Li Ping Chen Yanfeng Cheng Guomao Yin | 2009 | Materials and Design2009，，10： | 1 |
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