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| 1 | Current management of pediatric soft tissue sarcomas显示文摘Pediatric soft tissue sarcomas are a group of malignant neoplasms arising within embryonic mesenchymal tissues during the process of differentiation into muscle, fascia and fat. The tumors have a biphasic peak for age of incidence. Rhabdomyosarcoma(RMS) is diagnosed more frequently in younger children, whereas adult-type non-RMS soft tissue sarcoma is predominately observed in adolescents. The latter group comprises a variety of rare tumors for which diagnosis can be difficult and typically requires special studies, including immunohistochemistry and molecular genetic analysis. Current management for the majority of pediatric sarcomas is based on the data from large multi-institutional trials, which has led to great improvements in outcomes over recent decades. Although surgery remains the mainstay of treatment, the curative aim cannot be achieved without adjuvant treatment. Pre-treatment staging and risk classification are of prime importance in selecting an effective treatment protocol. Tumor resectability, the response to induction chemotherapy, and radiation generally determine the risk-group, and these factors are functions of tumor site, size and biology. Surgery provides the best choice of local control of small resectable tumors in a favorable site. Radiation therapy is added when surgery leaves residual disease or there is evidence of regional spread. Chemotherapy aims to reduce the risk of relapse and improve overall survival. In addition, upfront chemotherapy reduces the aggressiveness of the required surgery and helps preserve organ function in a number of cases. Long-term survival in low-risk sarcomas is feasible, and the intensity of treatment can be reduced. In high-risk sarcoma, current research is allowing more effective disease control. | Surasak Sangkhathat | 2015 | World Journal of Clinical Pediatrics2015，4，4： | 11 |
| 2 | Overall expression of beta-catenin outperforms its nuclear accumulation in predicting outcomes of colorectal cancers显示文摘AIM: To examine the expression of beta-catenin in colorectal cancer and look for association with other clinico-pathological parameters. METHODS: Tumor samples from 163 cases of colorectal cancer (CRC) who had undergone primary colectomy between May,1998 and November,2002 with complete follow-up data for either 5 years or until death were recruited for a beta-catenin immunohistochemical study. The percentage of immunoreacted tumor cells was defined as overall staining density (OSD) and percentage of cells having nuclear localization was counted as nuclear staining density (NSD). Univariate exploration used log-rank test and multivariate survival analysis used Cox's hazard regression model. RESULTS: Beta-catenin immunoreactivity was detected in 161 samples (98.8%),of which 131 cases had nuclear staining. High OSD (≥ 75%),detected in 123 cases (75.5%),was significantly associated with earlier clinical staging (P < 0.01),lower nodal status (P = 0.02),non-metastatic status (P < 0.01) and better differentiation (P = 0.02). Multivariate analysis found that high OSD was independently associated with better survival [Cox's hazard ratio 0.51,95% confidence interval (CI) 0.31-0.83]. Although high NSD (≥ 75%) was correlated with high pre-operative serum CEA (P = 0.03),well differentiation (P < 0.01),and increased staining intensity (P < 0.01),the parameter was not significantly associated with survival. CONCLUSION: Unlike previous reports,the study did not find a predictive value of nuclear beta-catenin in CRC. Instead,the overall expression of beta-catenin in CRC showed an association with better differentiation and earlier staging. Moreover,the parameter also independently predicted superior survival. | Worrawit Wanitsuwan Samornmas Kanngurn Teeranut Boonpipattanapong Rassamee Sangthong Surasak Sangkhathat | 2008 | World Journal of Gastroenterology2008，14，39： | 10 |
| 3 | Infliximab stopped severe gastrointestinal bleeding in Crohn's disease显示文摘To report the result of rapid ulcer healing by infliximab in Crohn's patients with severe enterocolic bleeding. During 2005 and 2010, inflammatory bowel disease database of King Chulalongkorn Memorial and Samitivej hospitals were reviewed. There were seven Crohn's disease (CD) patients (4 women and 3 men; mean age 52 ± 10.4 years; range: 11-86 years). Two of the seven patients developed severe gastrointestinal bleeding (GIB) as a flare up of CD whereas the other five patients presented with GIB as their first symptom for CD. Their mean hemoglobin level dropped from 12 ± 1.3 g/ dL to 8.7 ± 1.3 g/dL in a 3-d period. Median packed red blood cells units needed for resuscitation was 4 units. Because of uncontrolled bleeding, surgical resection was considered. However, due to the poor surgical candidacy of these patients (n = 3) and /or possible development of short bowel syndrome (n = 6), surgery was not pursued. Likewise angiographic embolization was not considered in any due to the risk of large infarction. All severe GIBs successfully stopped by one or two doses of intravenous infliximab. Our data suggests that infliximab is an alternative therapy for CD with severe GIB when surgery has limitation or patient is a high risk. | Satimai Aniwan Surasak Eakpongpaisit Boonlert Imraporn Surachai Amornsawadwatana Rungsun Rerknimitr | 2012 | World Journal of Gastroenterology2012，18，21： | 6 |
| 4 | 光量子随机数发生器显示文摘设计制作了基于单光子量子随机性的二进制随机数发生器,通过50/50光分束器的光子流被其后的单光子探测器记录下光子路径,经高速电路和计算机数据采集系统转换为二进制随机数流,目前实验中随机数采集速率达100Kbit/s,本文采用延迟符合计数法来克服探测器暗计数的影响。使暗计数对随机数序列的影响下降了2到3个数量级,最后应用的三种随机性测试表明所采数据随机性良好。 | 吴双 梁林梅 李承祖 Surasak Chiangga | 2005 | 量子光学学报2005，11，2： | 3 |
| 5 | A Potential Flow Based Flight Simulator for an Underwater Glider显示文摘在水下滑翔机是最近的创新类型自治在水下车辆(AUV ) 在海洋探索和观察使用了。他们调整快活潜水并且回到海洋表面。在高度的变化期间,他们使用力量由他们的翅膀开发了向前移动的水动力学。他们的班机被改变他们的重心和他们的快活的位置调整他们的修剪和脚跟角度控制。为更好的飞行控制,水动力学行为的理解和飞行力学在水下滑翔机是必要的。A 6-DOF 运动模拟器被结合为这个目的一个不稳定的潜在的流动模型。在一些特定的盒子中,数字学习证明一种不恰当的 stabilizer 尺寸能引起相反驾驶的行为。模拟器能被用来改进自动飞行控制。它能也被用于设备的水动力学设计优化。 | Surasak Phoemsapthawee Marc Le Boulluec Jean-Marc Laurens Fran ois Deniset | 2013 | Journal of Marine Science and Application2013，12，1： | 3 |
| 6 | Method of delivery and pregnancy outcomes in Asia: the WHO global survey on maternal and perinatal health 2007–08显示文摘 | Pisake Lumbiganon Malinee Laopaiboon A Metin Gülmezoglu Jo?o Paulo Souza Surasak Taneepanichskul Pang Ruyan Deepika Eranjanie Attygalle Naveen Shrestha Rintaro Mori Nguyen Duc Hinh Hoang Thi Bang Tung Rathavy Kang Chuyun Kannitha Cheang Mario Festin Venus | 2010 | The Lancet2010，，9713： | 2 |
| 7 | Ultrasound assisted extraction of anthraquinones from roots of Morinda citrifolia显示文摘 | Surasak H Prasert P Art iwan S | 2006 | Ult rasonic Sonochem2006，13，6： | 1 |
| 8 | The efficacy of a muscle exercise program to improve functional performance of the knee in patients with osteoarthritis显示文摘 | Kuptniratsaikul Vilai Tosayanonda Orchatara Nilganuwong Surasak | 2002 | Medical Association of Thailand Journal2002，1，85： | 1 |
| 9 | Molecular meehanisrns of praline mediated tolerance to toxic heavy metal in trans- genetic mieroalgae显示文摘 | SURASAK S SAMUEL T DESH V | 2002 | Plant Cell2002，14，11： | 1 |
| 10 | Complete Response of a Recurrent, Multicentric Malignant Glioma in a Patient Treated with Phenylbutyrate显示文摘 | Matthew J. Baker Steven Brem Stephanie Daniels Beverly Sherman Surasak Phuphanich | 2002 | Journal of Neuro - Oncology2002，，3： | 1 |
| 11 | Non-isothermal kinetics of the thermal decomposition of sodium oxalate Na2C20a 显示文摘 | Nopsiri Chaiyo Rangson Muanghlua Surasak Niemcharoen | 2012 | J Therm Anal Calorim2012，107，： | 1 |
| 12 | Immunoaffinity purification and characterization of cyclodextrin Glycosyltransferase from Bacillus circulans 显示文摘 | Jiraporn R Pomchai K Surasak L | 2001 | Science Asia2001，27，： | 1 |
| 13 | Ultrasound-Assisted Extraction of Anthraquinones from Roots of Morinda Citrifolia显示文摘 | SURASAK HEMWIMOL PRASERT PAVASANT ARTIWAN SHOTIPRUK | 2005 | Ultrasonics Sonochemistry2005，，： | 1 |
| 14 | Ultrasound-assisted extraction of anthraquinones from roots of Mofinda citrifolia 显示文摘 | Surasak Hemwimol | 2006 | Ultrasonics Sonochemistry2006，，13： | 1 |
| 15 | Ultrasound-assisted extraction of anthraquinones from roots of Morinda citrifolia显示文摘 | Surasak H Prasert P Artiwan S | 2006 | Ultrasonic Sonochem2006，13，： | 1 |
| 16 | Formation of cell spheroids using Standing Surface Acoustic Wave(SSAW)显示文摘3D bioprinting becomes one of the popular approaches in the tissue engineering.In this emerging application,bioink is crucial for fabrication and functionality of constructed tissue.The use of cell spheroids as bioink can enhance the cell-cell interaction and subsequently the growth and differentiation of cells in the 3D printed construct with the minimum amount of other biomaterials.However,the conventional methods of preparing the cell spheroids have several limitations,such as long culture time,low-throughput,and medium modification.In this study,the formation of cell spheroids by SSAW was evaluated both numerically and experimentally in order to overcome the aforementioned limitations.The effects of excitation frequencies on the cell accumulation time,diameter of the formed cell spheroids,and subsequently,the growth and viability of cell spheroids in the culture medium over time were studied.Using the high-frequency(23.8 MHz)excitation,cell accumulation time to the pressure nodes could be reduced in comparison to that of the low-frequency(10.4 MHz)excitation,but in a smaller spheroid size.SSAW excitation at both frequencies does not affect the cell viability up to 7 days,>90%with no statistical difference compared with the control group.In summary,SSAW can effectively prepare the cell spheroids as bioink for the future 3D bioprinting and various biotechnology applications(e.g.,pharmaceutical drug screening and tissue engineering). | Yannapol Sriphutkiat Surasak Kasetsirikul Yufeng Zhou | 2018 | International Journal of Bioprinting2018，4，1： | 1 |
| 17 | Experimental and theoretical formability analysis using strain and stress based forming limit diagram for advanced high strength steels显示文摘 | Sansot Panich Frédéric Barlat Vitoon Uthaisangsuk Surasak Suranuntchai Suwat Jirathearanat | 2013 | Materials&Design2013，51，： | 1 |
| 18 | Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma显示文摘 | Surasak Phuphanich Christopher J. Wheeler Jeremy D. Rudnick Mia Mazer HongQian Wang Miriam A. Nu?o Jaime E. Richardson Xuemo Fan Jianfei Ji Ray M. Chu James G. Bender Elma S. Hawkins Chirag G. Patil Keith L. Black John S. Yu | 2013 | Cancer Immunology, Immunotherapy2013，，： | 1 |
| 19 | Volumetric analysis of liver segments in 155 living donors显示文摘 | Surasak L Yasuhiko SA Junichi K | 2002 | Liver Transpl2002，8，7： | 1 |
| 20 | Cadmium-tolerant bacteria reduce the uptake of cadmium in rice:Potential for microbial bioremedi- ation显示文摘 | SURASAK S WILAILAK S | 2013 | Ecotoxicology and Environmental Safety2013，94，1： | 1 |
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