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| 1 | SHRIMP U-Pb geochronology of the zircons from the Precambrian basement of the Qilian Block and its geological significances显示文摘Origin and tectonic evolution of the Qilian Precambrian basement on NW China were investigated using zircon U-Pb ages with collaborating stratigraphic and paleontological evidence. Zircon grains were separated from two schists, two granitic gneisses and one mylonized gneiss and dated with SHRIMP. Seventy percent of sixty-one detrital zircon ages from two schists ranges from 0.88 Ga to 3.09 Ga, mostly within 1.0 Ga to 1.8 Ga with a peak at 1.6 Ga to 1.8 Ga, and twenty percent varies from 2.0 Ga to 2.5 Ga. A few falls in the Archean and Neoproterozoic periods. The two granitic gneisses were dated 930±8 Ma and 918±14 Ma, whereas the mylonized granitic gneiss was dated 790±12 Ma. These ages represent two periods of magmatisms, which can be correlated with the early and late stages of magmatisms associated with the Jinningian movement on the Yangtze Blocks. The results from this and previous studies indicate that the ages of the Precambrian detrital zircons from the Qilian Block are widely distributed in the Proterozoic era, distinct from the North China Block which was stable in the Neo-Mesoproterozoic era. By contrast, the age histograms of the detrital zircons from the Qilian Block is similar to those from Precambrian basement of the Yangtze Craton. Therefore, it is suggested that the Qilian Block had a strong affinity toward the Yangtze Craton and might belong to the supercontinent Gondwana in the Neoproterozoic time. This inference is supported by Nd model age (TDM), stratigraphic, and paleontological evidence. It is further considered that the Qilian Block was rifted from the supercontinent Gondwana during late Sinian to form an isolated continent in the Proto-Tethyan Ocean, moving towards the Alaxa Block in the North China Craton. The part of Proto-Tethyan Ocean between the Qilian and Alaxa Blocks should correspond to the so-called Paleo-Qilian Ocean. Following the closure of the Paleo-Qilian Ocean in the early Paleozoic, the Qilian Block collided with the Alaxa Block to form the North Qilian Orogenic Belt. Based on this tectonic explanation, the North Qilian ophiolites should represent parts of lithosphere from the Proto-Tethyan Ocean. Lithological and geochronological evidence also indicates that the Qilian Block underwent continental reactivation possibly induced by the deep northward subduction of the North Qaidam Block in early Paleozoic time. | Kuoan TUNG Huai-Jen YANG Houng-Yi YANG LIU DunYi ZHANG JianXin WAN YuSheng Chien-Yuan TSENG | 2007 | Chinese Science Bulletin2007,52,19: | 42 |
| 2 | Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments显示文摘Chronic hepatitis B(CHB)virus infection is a global public health problem,affecting more than 400 million people worldwide.The clinical spectrum is wide,ranging from a subclinical inactive carrier state,to progressive chronic hepatitis,cirrhosis,decompensation,and hepatocellular carcinoma.However,complications of hepatitis B virus(HBV)-related chronic liver disease may be reduced by viral suppression.Current international guidelines recommend first-line treatment of CHB infection with pegylated interferon,entecavir,or tenofovir,but the optimal treatment for an individualpatient is controversial.The indications for treatment are contentious,and increasing evidence suggests that HBV genotyping,as well as serial on-treatment measurements of hepatitis B surface antigen and HBV DNA kinetics should be used to predict antiviral treatment response.The likelihood of achieving a sustained virological response is also increased by extending treatment duration,and using combination therapy.Hence the paradigm for treatment of CHB is constantly evolving.This article summarizes the different indications for treatment,and systematically reviews the evidence for the efficacy of various antiviral agents.It further discusses the shortcomings of current guidelines,use of rescue therapy in drug-resistant strains of HBV,and highlights the promising clinical trials for emerging therapies in the pipeline.This concise overview presents an updated practical approach to guide the clinical management of CHB. | Ceen-Ming Tang Tung On Yau Jun Yu | 2014 | World Journal of Gastroenterology2014,20,20: | 41 |
| 3 | Renminbi Internationalization: Progress, Prospect and Comparison显示文摘<正>Using principal component analyses,this paper constructs two internationalization indices for the renminbi(RMB) and 32 other major currencies.We find that the RMB’s currency internationalization degree index(CIDI) is still low,and far behind the 4 most important international currencies.In 2009,it was ranked 18th among all important international currencies.However,in terms of the currency internationalization prospect index(CIPI), the RMB has remained the world’s fifth highest since 2006.Although it is still far behind the US dollar and the euro,surpassing the ranking of the yen and the pound is possible in the near future.The dramatic difference in the ranking between the CIDI and the CIPI is a result of China’s tight capital account control,the usage continuity of international currency due to network externalities,and the narrow foreign exchange and imperfect financial markets.Hence,to a large degree,the RMB’s potential as an international currency depends on China’s capital account liberalization. | Chen-yuan Tung Guo-chen Wang Jason Yeh | 2012 | China & World Economy2012,20,5: | 39 |
| 4 | Distinctive roles of unsaturated and saturated fatty acids in hyperlipidemic pancreatitis显示文摘AIM: To investigate how the saturated and unsaturated fatty acid composition influences the susceptibility of developing acute pancreatitis. METHODS: Primary pancreatic acinar cells were treated with low and high concentrations of different saturated and unsaturated fatty acids, and changes in the cytosolic Ca2+ signal and the expression of protein kinase C(PKC) were measured after treatment. RESULTS: Unsaturated fatty acids at high concentrations, including oleic acid, linoleic acid, palmitoleic acid, docosahexaenoic acid, and arachidonic acid, induced a persistent rise in cytosolic Ca2+ concentrations in acinar cells. Unsaturated fatty acids at low concentrations and saturated fatty acids, including palmitic acid, stearic acid, and triglycerides, at low and high concentrations were unable to induce a rise in Ca2+ concentrations in acinar cells. Unsaturated fatty acids at high concentrations but not saturated fatty acids induced intra-acinar cell trypsin activation and cell damage and increased PKC expression.CONCLUSION: At sufficiently high concentrations, unsaturated fatty acids were able to induce acinar cells injury and promote the development of pancreatitis. Unsaturated fatty acids may play a distinctive role in the pathogenesis of pancreatitis through the activation of PKC family members. | Yu-Ting Chang Ming-Chu Chang Chien-Chih Tung Shu-Chen Wei Jau-Min Wong | 2015 | World Journal of Gastroenterology2015,21,32: | 29 |
| 5 | Finding of Neoproterozoic (~775 Ma) magmatism recorded in metamorphic complexes from the North Qilian orogen: Evidence from SHRIMP zircon U-Pb dating显示文摘标明日期的虾 U-Pb 从 Niuxinshan 片麻岩的花岗石和 Leigongshan 在锆石上被执行在北方 Qilian orogen 的片麻岩的吨子盐, NW 中国。结果分别地产出 776+-10 妈和 774 +-23 妈的加权的平均 ~(206 )Pb/~(238 ) U 年龄。Igneousmorphology,摆动的 zonings,和为这些锆石的相对高的 Th/U 比率建议 magmaticorigin。这些年龄作为岩浆炮兵阵地预定并且因此代表 aNeoproterozoic (约 775 妈) 被解释在北方 Qilian 区域的 magmatic 事件。thismagmatism 可能与超级大陆 Rodinia 的决裂有关,这被建议。这发现,和 750 ~ 800 妈的类似的年龄为南方中央的 Qilian 和北方 Qaidam 的附近的岩层报导了,具有到在韦斯特中国的 Rodinia 进化的理解的意义。 | Chien-Yuan Tseng Houng-Yi Yang WAN Yusheng LIU Dunyi Da-Jen Wen Tzung-Chi Lin Kuo-An Tung | 2006 | Chinese Science Bulletin2006,51,8: | 26 |
| 6 | SHRIMP U-Pb geochronology of the detrital zircons from the Longshoushan Group and its tectonic significance显示文摘Sixty-two geologically meaningful U-Pb dates were obtained by using SHRIMP technique for the detrital zircons in three metasedimentary rocks from stratigraphically uppermost parts of the Longshoushan Group in the present study. Eighty percents of these dates range from 1.7 Ga to 2.2 Ga with a peak at 1.8-2.0 Ga and twenty percents from 2.3 Ga to 2.7 Ga. The youngest detrital zircon is dated at 1724±19 Ma which is interpreted as the maximum depositional age of the metasedimentary rocks. Therefore, the age for the diagenesis and lithification of the original sedimentary rocks of the Longshoushan Group before the metamorphism must be younger than 1724±19 Ma. Comparison of the age histograms of these detrital zircons with the ages of the igneous rocks on the surrounding older massifs suggests that the sediments of the Longshoushan Group were most likely derived from the Alaxa Block and Tarim Craton. This implies that the affinity between Alaxa Block and Tarim Craton was strong and that they might have been a unified craton during middle-early Proterozoic time. | KuoAn TUNG HoungYi YANG LIU DunYi ZHANG JianXin ChienYuan TSENG WAN YuSheng | 2007 | Chinese Science Bulletin2007,52,10: | 24 |
| 7 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences . 1998 (1971)1998,,1971: | 22 |
| 8 | CrN活塞环涂层的摩擦学性能显示文摘以PVD方法在不锈钢渗氮活塞环基体上沉积了厚约 30μm的CrN涂层。采用 2种GF-3等级的全配方发动机油作为润滑剂,在SRV试验机上,对比了具有 /没有CrN涂层的不锈钢渗氮活塞环的摩擦学性能。试验结果表明,CrN涂层能使摩擦因数数较快的稳定且数值较低,同时活塞环及其对磨缸套的磨损量也大大降低,对磨缸套的磨损量减少了80%以上。SEM分析结果表明,由于CrN涂层具有较高的硬度和较低的表面粗糙度,可以降低磨粒磨损,且能使对磨的缸套试样较快地与之适配,从而促进了摩擦反应膜的形成和扩展,是摩擦因数和磨损量降低的主要原因。 | 赵晚成 马亚军 李生华 金元生 王玉琮 Simon C Tung | 2005 | 润滑与密封2005,30,2: | 21 |
| 9 | Risk factors and therapeutic response in Chinese patients with peptic ulcer disease显示文摘AIM:To assess the risk factors and the eff icacy of medications of patients with gastric and duodenal ulcers among Chinese patients in Taiwan.METHODS:Patients with peptic ulcers,diagnosed by upper endoscopy,were retrospectively collected between January 2008 and December 2008.The differences were compared.RESULTS:Among all 448 cases,254(56.6%) and 194(43.4%) patients had gastric ulcers and duodenal ulcers respectively.Patients with gastric ulcers were younger than those with duodenal ulcers.Although more men existed,there was a female predominance in middle-aged cases.Patients with duodenal ulcers had a higher rate of Helicobacter pylori(H.pylori) infection(62.4% vs 43.3%,P = 0.001),and those with gastric ulcers owned a significantly higher amount of aspirin and nonsteroidal anti-inflammatory drug(NSAID) use(7.5% vs 1.5%,6.7% vs 2.1%,P = 0.001).Tobacco smoking and alcohol drinking had no different impact between these two groups.Proton-pump inhibitors and H2-receptor antagonists(H2RA) were effective,but significantly less so in cases with duodenal ulcers receiving H2RAs,or in those with H.pylori infection and a history of NSAID use.CONCLUSION:Patients with gastric ulcers had lower H.pylori infection but more aspirin or NSAID use.Antisecretory therapy was ineffective in gastric ulcers underwent H2RA treatment,and cases combined H.pylori infection and NSAID use. | Shou-Wu Lee Teng-Yu Lee Hong-Zen Yeh Chun-Fang Tung Yen-Chun Peng | 2010 | World Journal of Gastroenterology2010,16,16: | 19 |
| 10 | 二烷基二硫代甲酸钼和二烷基二硫代磷酸钼对缸套/活塞环摩擦学行为的影响显示文摘在 12 5℃和 32 0℃下 ,以全配方矿物基 SJ/5 W- 30型发动机油作为基础润滑油 ,考察了油溶性有机钼添加剂Mo DTC与 Mo DTP对灰铸铁缸套 /喷钼活塞环摩擦学行为的影响 .结果表明 :Mo DTC可以改善基础油的减摩抗磨性能 ,而 Mo DTP仅表现出一定的抗磨作用 ;试验温度对缸套 -活塞环的摩擦磨损性能具有重要影响 .X射线光电子能谱分析表明 :缸套磨损表面主要含有铁氧化物、氧化钼、硫化铁、二硫化钼以及磷酸盐等 ,其含量与添加剂类型和摩擦磨损试验温度有关 .12 5℃下在缸套磨损表面上减摩组分 Mo S2 和其它耐磨组分的含量较高 ,这是 Mo DTC具有较好减摩耐磨性能的主要原因 . | 张瑞军 李生华 金元生 王玉琮 TUNG Simon C | 2001 | 摩擦学学报2001,21,3: | 18 |
| 11 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | 1998 (1971)1998,,1971: | 18 |
| 12 | Template-free large-scale synthesis of g-C3N4 microtubes for enhanced visible light-driven photocatalytic H2 production显示文摘 | Chao Zhou Run Shi Lu Shang Li-Zhu Wu Chen-Ho Tung Tierui Zhang | 2018 | Nano Research2018,11,6: | 17 |
| 13 | How can colorectal neoplasms be treated during colonoscopy?显示文摘AIM: For many physicians who ordinarily treat patients with colonic diseases, colonoscopy is considered a prime study interest. Developments in colonoscopic equipment and methods have led to a large number of endoscopic diagnoses and treatment for colorectal neoplasms. The purpose of this investigation is to evaluate the efficacy and outcomes of endoscopic treatment for colorectal neoplastic lesions.METHODS: From September 1999 to May 2003, 11 447 consecutive colonoscopic examinations in 9 864 patients were gathered; totaling 5 502 endoscopic treatments for colorectal neoplasms. Macroscopic characteristics of the neoplasms were classified into protruded (n = 3 953), sessile (n = 1 402), lateral spreading tumor (n = 139) and depressed lesions (n = 8). Snare polypectomy was conducted in 3 984 lesions, hot forcep removal in 1 368 lesions, and endoscopic mucosal resection in 150 lesions.RESULTS: Histological diagnoses were 4 596 neoplastic lesions (4 376 adenomas and 220 adenocarcinomas) and 906 non-neoplastic lesions (891 hyperplastic and 15 inflammatory polyps). For the adenocarcinoma group, 31 instances involved submucosal invasion or resection margin, who received further operations, while 13 surgical specimens discovered no residual tumors. Three perforations and 96 bleedings were found following endoscopic treatment. No procedure-related mortality was found and no recurrent malignancy was found after 1456 mo follow-up.CONCLUSION: To lower the incidence and mortality of colorectal cancer, endoscopic treatment for colorectalneoplasms is a simple and safe procedure. | Yu-Pin Ho Chen-Ming Hsu Jau-Min Lien Shui-Yi Tung Cheng-Shyong Wu | 2005 | World Journal of Gastroenterology2005,11,18: | 15 |
| 14 | Supramolecular precursor strategy for the synthesis of holey graphitic carbon nitride nanotubes with enhanced photocatalytic hydrogen evolution performance显示文摘A simple one-step thermal polymerization method was developed for synthesis of holey graphitic carbon nitride nanotubes,involving direci eating of mixtures of melamine and urea or melamine and cyanuric acid in specific mass ratios.Supramolecular structures formed betweer the precursor molecules guided nanotube formation.The porous and nanotubular structure of the nanotubes facilitated efficient charge carrier nigration and separation,thereby enhancing photocatalytic Hz production in 20 vol.%lactic acid under visible light irradiation.Nanotubes synthesized using melamine and urea in a 1:10 mass ratio(denoted herein as CN-MU nanotubes)exhibited a photocatalytic hydroger production rate of 1,073.6μmol·h^-1·^-g with Pt as the cocatalyst,a rate of 4.7 and 3.1 times higher than traditional Pt/g-CN4 photocatalysts prepared from graphitic carbon nitride(g-CN4)obtained by direct thermal polymerization of melamine or urea,respectively.On the basis of their outstanding performance for photocatalytic H2 production,it is envisaged that the holey g-C3N4 nanotubes will find widespread uptake in other areas,including photocatalytic CO2 reduction,dye-sensitized solar cells and photoelectrochemical sensors. | Xiaoshuai Wang Chao Zhou Run Shi Qinqin Liu Geoffrey I. N. Waterhouse Lizhu Wu Chen-Ho Tung Tierui Zhang | 2019 | Nano Research2019,12,9: | 15 |
| 15 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | Proceedings of the Royal Society A: Mathematical Physical and Engineering Sciences1998,,1971: | 15 |
| 16 | Evaluation of a simulation-based workshop on clinical performance for emergency physicians and nurses显示文摘BACKGROUND: Simulation-based medical education has been growing rapidly and becomes one of the most popular teaching methods for improving patient safety and patient care. The Simulation Subcommittee of the Hong Kong College of Emergency Medicine organized an educational program emphasizing the team training, clinical decision-making and communication skills. This study aimed to evaluate the attitude of the participants toward a new training program and the change in the knowledge on clinical performance in emergency physicians and nurses after attending the educational program.METHODS: A course evaluation form was filled in by the participants at the end of the workshop. An assessment of 20 multiple-choice questions with 5 options was administered to the participants before and after the 2-day simulation-based training workshop.RESULTS: A total of 72 doctors and nurses working in the Accident and Emergency Department were enrolled. The average pretest and posttest scores were 12 and 14.3 respectively. The percentage improvement in the mean score of the pretest and posttest was 11.5%. The Chi-square test showed signifi cant improvement in the pretest and posttest score grading(P=0.00). Paired t-test revealed signifi cant difference between the mean scores of the pretest and posttest(P=0.00).CONCLUSIONS: Participants had positive attitude toward this new training program. Significant improvement of the knowledge on clinical performance in healthcare professionals in the Accident and Emergency Department was observed after the participation in this simulation-based educational program. | Chi Ho Chan Tung Ning Chan Man Cheuk Yuen Wai Kit Tung | 2015 | World Journal of Emergency Medicine2015,6,1: | 14 |
| 17 | The potential for liquid biopsies in the precision medical treatment of breast cancer显示文摘Currently the clinical management of breast cancer relies on relatively few prognostic/predictive clinical markers(estrogen receptor, progesterone receptor, HER2), based on primary tumor biology. Circulating biomarkers, such as circulating tumor DNA(ctDNA) or circulating tumor cells(CTCs) may enhance our treatment options by focusing on the very cells that are the direct precursors of distant metastatic disease, and probably inherently different than the primary tumor's biology. To shift the current clinical paradigm, assessing tumor biology in real time by molecularly profiling CTCs or ctDNA may serve to discover therapeutic targets, detect minimal residual disease and predict response to treatment. This review serves to elucidate the detection,characterization, and clinical application of CTCs and ctDNA with the goal of precision treatment of breast cancer. | Victoria A.Forte Dany K.Barrak Mostafa Elhodaky Lily Tung Anson Snow Julie E.Lang | 2016 | Cancer Biology & Medicine2016,13,1: | 13 |
| 18 | Clinical correlation of gallstone disease in a Chinese population in Taiwan:Experience at Cheng Hsin General Hospital显示文摘瞄准:在与它有关的台湾和联系条件的因素探索胆石疾病(GSD ) 的流行。方法:我们自愿地学习了 2386 个健康成年人(1235 男性和 1151 女性) 的一个总数为在 2002 年 1 月和 2002 年 12 月之间的付的物理检查承认了到 Cheng Hsin 医院将军。血样品和超声 sonography 结果是镇定的。结果:在这张学习人口之中的 GSD 的全面流行是 5.3% ,包括 1.7%(n=40 ) 有一块单个石头, 2.3%(n=55 ) 有多重石头,并且 1.3%(n=31 ) 有胆囊炎。流行与增加年龄(P<0.0001 ) 揭示了统计上重要的增加。女性们比展出了多重石头的更大的流行做了男性(3.0% 对 1.7% , P=0.04 ) 。用多重逻辑回归分析,下列看起来是显著地与 GSD 的流行有关:老年(40-49 年对 <
40 年, OR=1.63 [95% CI:0.76-3.48 ] , 50-59 年对 <
40 年, OR=4.93 [95% CI:2.43-9.99 ] , 60-69 年对 <
40 年, OR=6.82 [95% CI:3.19-14.60 ] , >
或 = 70 年对 <
40 年, OR=10.65 [95% CI:4.78-23.73 ]) ,更高的 BMI (>
或 = 27 kg/m2 对 <
24 kg/m2,调整 OR=1.74 [95% CI:1.04-2.88 ]) ,并且更高的 FPG (>
或 = 126 mg/dL 对 <
110 mg/dL, OR=1.71, 95%CI:1.01-2.96 ) 。结论:老年(>
或 = 50 年) ,肥胖(BMI >
或 = 27 kg/m2 ) ,并且类型 2 糖尿病(FPG >
或 = 126 mg/dL ) 与 GSD 的流行被联系。 | Chi-Ming Liu Tao-Hsin Tung Pesus Chou Victor Tze-Kai Chen Chung-Te Hsu Wu-Shyong Chien Yeu-Tyng Lin Hsu-Feng Lu Hui-Chuan Shih Jorn-Hon Liu | 2006 | World Journal of Gastroenterology2006,12,8: | 11 |
| 19 | “原位开窗”技术重建主动脉弓上分支血管的Meta分析显示文摘目的系统评价应用'原位开窗'技术治疗胸主动脉(夹层)动脉瘤重建主动脉弓上分支血管的安全性及有效性。方法收集截止2018年8月前发表的关于应用'原位开窗'技术腔内修复主动脉弓部病变(夹层/动脉瘤),同时保留弓上血管血供的文献,回顾性分析技术成功率、内漏发生率、并发症发生率及病死率等近中期临床结果。结果共纳入11篇文献的262例胸主动脉(夹层)动脉瘤患者,技术成功率为94%,平均随访时间为16.85个月,共13例患者出现术后支架内漏(Ⅰ型内漏10例,Ⅱ型内漏3例),术后内漏总发生率为8%,30天病死率和随访期手术相关病死率分别为3.44%和0。结论应用'原位开窗'技术重建弓上分支血管技术成功率较高,并发症发生率及病死率较低。 | 周楚 Tung On Yau 乔彤 | 2018 | 中国血管外科杂志(电子版)2018,10,3: | 11 |
| 20 | 渗氮活塞环表面磁控溅射MoN涂层的摩擦学性能显示文摘利用磁控溅射方法在渗氮活塞环基体上沉积了厚约4μm的MoN涂层;以GF-3等级的全配方发动机油作为润滑剂,采用SRV型高温摩擦磨损试验机对比考察了沉积MoN涂层前后渗氮活塞环的摩擦学性能.结果表明,沉积MoN涂层后摩擦系数较低且较快达到稳定状态;与此同时,活塞环和缸套磨损大幅减小.其原因在于硬度很高的MoN涂层不易产生磨粒,且同缸套试样具有良好的匹配性能. | 马亚军 李生华 潘国顺 金元生 王玉琮 TUNG S C | 2004 | 摩擦学学报2004,24,4: | 11 |