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| 1 | 国际宫颈腺癌标准和分类:宫颈浸润性腺癌一种新的病理分类显示文摘与2014版WHO分类不同,作者试图根据与病因[即人类乳头瘤病毒(HPV)感染]相关的形态学特征对宫颈腺癌(ECAs)进行分类。该文描述的国际宫颈腺癌标准和分类(IECC标准)将ECAs区分为两种类型,即人乳头状瘤病毒相关性腺癌(HPVA)(高倍可见腺上皮的核分裂和细胞凋亡)和无或有限的HPVA特征的宫颈腺癌[非人类乳头状瘤病毒相关性腺癌(HPVA)],然后根据胞质特点对HPVA进行分类(主要是提供与现有分类方案的连续性)。 | 解建军 张仁亚 Stolnicu S Barsan I Hoang L | 2018 | 临床与实验病理学杂志2018，34，11： | 74 |
| 2 | The UCR Time Series Archive显示文摘The UCR time series archive–introduced in 2002,has become an important resource in the time series data mining community,with at least one thousand published papers making use of at least one data set from the archive.The original incarnation of the archive had sixteen data sets but since that time,it has gone through periodic expansions.The last expansion took place in the summer of 2015 when the archive grew from 45 to 85 data sets.This paper introduces and will focus on the new data expansion from 85 to 128 data sets.Beyond expanding this valuable resource,this paper offers pragmatic advice to anyone who may wish to evaluate a new algorithm on the archive.Finally,this paper makes a novel and yet actionable claim:of the hundreds of papers that show an improvement over the standard baseline(1-nearest neighbor classification),a fraction might be mis-attributing the reasons for their improvement.Moreover,the improvements claimed by these papers might have been achievable with a much simpler modification,requiring just a few lines of code. | Hoang Anh Dau Anthony Bagnall Kaveh Kamgar Chin-Chia Michael Yeh Yan Zhu Shaghayegh Gharghabi Chotirat Ann Ratanamahatana Eamonn Keogh | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，6： | 26 |
| 3 | Role of hepatitis B virus DNA integration in human hepatocarcinogenesis显示文摘Liver cancer ranks sixth in cancer incidence,and is the third leading cause of cancer-related deaths worldwide.Hepatocellular carcinoma(HCC)is the most common type of liver cancer,which arises from hepatocytes and accounts for approximately 70%-85%of cases.Hepatitis B virus(HBV)frequently causes liver inflammation,hepatic damage and subsequent cirrhosis.Integrated viral DNA is found in 85%-90%of HBV-related HCCs.Its presence in tumors from non-cirrhotic livers of children or young adults further supports the role of viral DNA integration in hepatocarcinogenesis.Integration of subgenomic HBV DNA fragments into different locations within the host DNA is a significant feature of chronic HBV infection.Integration has two potential consequences:(1)the host genome becomes altered('cis'effect);and(2)the HBV genome becomes altered('trans'effect).The cis effect includes insertional mutagenesis,which can potentially disrupt host gene function or alter host gene regulation.Tumor progression is frequently associated with rearrangement and partial gain or loss of both viral and host sequences.However,the role of integrated HBV DNA in hepatocarcinogenesis remains controversial.Modern technology has provided a new paradigm to further our understanding ofdisease mechanisms.This review summarizes the role of HBV DNA integration in human carcinogenesis. | Hoang Hai Akihiro Tamori Norifumi Kawada | 2014 | World Journal of Gastroenterology2014，20，20： | 22 |
| 4 | 新型口服抗凝药对我国非瓣膜性心房颤动患者治疗效果与安全性的Meta分析显示文摘背景非瓣膜性心房颤动(NVAF)是临床常见的心律失常,常引起栓塞事件发生,故抗凝治疗在NVAF治疗中尤为重要。华法林已被证实为有效的传统口服抗凝药,但出血风险高等缺点限制了其临床应用。近年来出现的新型口服抗凝药(NOACs)弥补了华法林的缺陷而备受临床关注。目的评价NOACs对国内NVAF患者治疗的效果与安全性。方法 2015年9月——2016年8月,计算机检索Cochrane Library、Pub Med、Web of Science、EMBase、中国知网、中国生物医学文献数据库、维普网和万方数据知识服务平台,筛选关于NOACs与华法林对NVAF患者治疗比较的随机对照试验(RCT)。提取纳入文献相关信息,并评价纳入文献质量。结果纳入15篇文献,共2 246例患者,文献质量评分为4~5分。Meta分析显示,与华法林比较,NOACs可降低NVAF患者脑卒中发生率〔OR=0.65,95%CI(0.43,0.97),P=0.04〕、非严重性出血发生率〔OR=0.44,95%CI(0.31,0.61),P<0.001〕及严重性出血发生率〔OR=0.45,95%CI(0.22,0.91),P=0.03〕;而非神经系统性血栓栓塞发生率比较,差异无统计学意义〔OR=0.72,95%CI(0.46,1.14),P=0.16〕。结论采用NOACs治疗NVAF患者脑卒中、非严重性出血及严重性出血发生率低于华法林,非神经系统性血栓栓塞发生率与华法林无差异,NOACs用于治疗国内NVAF患者具有良好的效果和安全性。 | 颜建龙 赛音夫 LAM HOANG TRUC 邵文明 谭国强 张爱东 | 2017 | 中国全科医学2017，20，11： | 21 |
| 5 | 中越水稻迁飞性害虫稻飞虱、稻纵卷叶螟发生关系分析显示文摘中越两国同属东亚季风区,水稻病虫害在发生危害上为一个整体。每年水稻稻飞虱、稻纵卷叶螟(以下简称'两迁'害虫)随着季节和气温变化,在两国间往返迁飞,发生为害,相互影响。研究两国水稻迁飞性害虫发生的关系和影响规律,对于提高监测预警的早期预见性和防控工作的主动性,有效控制其危害具有重要意义。2010年以来,中越两国实施了中越水稻迁飞性害虫监测与防治合作项目,通过连续多年开展交流合作,初步明确了越南'两迁'害虫发生规律。本文简要分析了影响越南'两迁'害虫发生的主要因素,探讨了中越两国水稻'两迁'害虫发生规律的相关性,对提高中国'两迁'害虫中、长期预报能力和综合治理水平发挥了积极作用。 | 陆明红 刘万才 胡高 翟保平 Hoang Anh Tuan Do Hong Khanh | 2018 | 植物保护2018，44，3： | 18 |
| 6 | Stable Vertical Takeoff of an Insect-Mimicking Flapping-Wing System Without Guide Implementing Inherent Pitching Stability显示文摘 | Hoang Vu Phan Quoc Viet Nguyen Quang Tri Truong Tien Van Truong Hoon Cheol Park Nam Seo Goo Doyoung Byun Min Jun Kim | 2012 | Journal of Bionic Engineering2012，9，4： | 16 |
| 7 | 绿肥间作对茶树根际土壤真菌群落的影响显示文摘通过IonS5TM XL高通量测序技术探讨了茶园间作光叶苕子-茶肥1号(CF)、湘野豌1号-田菁(TJ)、肥田萝卜-圆叶决明(JM)对茶树根际土壤真菌群落结构特征和土壤养分的影响。结果表明:与对照(无间作)相比,间作绿肥提高了土壤有机质、全氮、碱解氮、有效磷和速效钾的含量,其提高幅度分别为1.19%~23.79%、0.87%~12.17%、4.37%~14.34%、23.08%~62.12%和7.70%~44.06%。茶树根际土壤真菌Shannon指数和Chaos指数的变化趋势均为TJ>CK>JM>CF,其中TJ与CF处理间差异显著(P<0.05),其他处理间差异不显著(P>0.05)。被孢霉门(Mortierellomycota)、子囊菌门(Ascomycota)和担子菌门(Basidiomycota)为茶树根际土壤中三大优势真菌门,绿肥间作提高了担子菌门的相对丰度,降低了球囊菌门(Glomeromycota)和罗兹菌门(Rozellomycota)的相对丰度;被孢霉纲(Mortierellomycetes)、银耳纲(Tremellomycetes)和粪壳菌纲(Sordariomycets)为三大优势菌纲;沙蜥属(Saitozyma)、被孢霉属(Mortierell)和镰刀霉属(Fusarium)为3大优势菌属。冗余(RDA)分析结果显示,土壤全磷、有效磷、有机质、全氮和碱解氮影响茶树根际土壤真菌群落结构。经FUNGuild软件平台分析显示,茶树根际包含如下生态功能群:未定义腐生菌、丛枝菌根、真菌寄生菌、木质腐生菌、动物病原菌、植物病原菌、外生真菌等。茶园间作绿肥翻埋还田,能有效调节茶树根际土壤真菌群组成,改善茶园土壤生态环境,是实现茶叶绿色可持续发展的重要措施。 | 傅海平 周品谦 王沅江 莫泽东 李泽恒 马青平 Hoang Ha Nguyen 黎星辉 | 2020 | 茶叶通讯2020，47，3： | 15 |
| 8 | 基于有限元的含均匀腐蚀缺陷油气管道剩余强度显示文摘针对油气管道随服役年限延长腐蚀日益严重的问题,运用有限元分析软件ANSYS Workbench,对含均匀腐蚀缺陷的金属油气管道进行综合分析,研究轴向腐蚀长度、环向腐蚀长度、腐蚀深度、相邻腐蚀间距等对管道剩余强度的影响。分析表明:(1)轴向腐蚀缺陷越长,管道剩余强度越小。(2)当环向腐蚀缺陷长度较长时,对管道的剩余强度影响不大,当环向腐蚀缺陷较短时,可以将缺陷近似视为裂纹处理。(3)随着腐蚀深度的增加,管道剩余强度迅速减小。(4)对于两相邻轴向腐蚀缺陷,当轴向间距小于20 mm时,可将两个缺陷视为一个整体缺陷计算管道剩余强度;当腐蚀缺陷轴向间距大于20 mm时,则分别计算两个缺陷对应的管道剩余强度,取其中较小值。 | HOANG Van Thanh 龙伟 刘华国 李金刚 | 2018 | 油气储运2018，37，2： | 14 |
| 9 | Real-time in situ three-dimensional integral videography and surgical navigation using augmented reality: a pilot study显示文摘To evaluate the feasibility and accuracy of a three-dimensional augmented reality system incorporating integral videography for imaging oral and maxillofacial regions, based on preoperative computed tomography data. Three-dimensional surface models of the jawbones, based on the computed tomography data, were used to create the integral videography images of a subject's maxillofacial area. The three-dimensional augmented reality system (integral videography display, computed tomography, a position tracker and a computer) was used to generate a three-dimensional overlay that was projected on the surgical site via a half-silvered mirror. Thereafter, a feasibility study was performed on a volunteer. The accuracy of this system was verified on a solid model while simulating bone resection. Positional registration was attained by identifying and tracking the patient/surgical instrument's position. Thus, integral videography images of jawbones, teeth and the surgical tool were superimposed in the correct position. Stereoscopic images viewed from various angles were accurately displayed. Change in the viewing angle did not negatively affect the surgeon's ability to simultaneously observe the three-dimensional images and the patient, without special glasses. The difference in three-dimensional position of each measuring point on the solid model and augmented reality navigation was almost negligible (<1 mm); this indicates that the system was highly accurate. This augmented reality system was highly accurate and effective for surgical navigation and for overlaying a three-dimensional computed tomography image on a patient's surgical area, enabling the surgeon to understand the positional relationship between the preoperative image and the actual surgical site, with the naked eye. | Hideyuki Suenaga Huy Hoang Tran Hongen Liao Ken Masamune Takeyoshi Dohi Kazuto Hoshi Yoshiyuki Mori Tsuyoshi Takato | 2013 | International Journal of Oral Science2013，5，2： | 11 |
| 10 | Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors显示文摘 | Zhu, Jie Ming, Chang Fu, Xin Duan, Yaou Duc Anh Hoang Rutgard, Jeffrey Zhang, Runze Wang, Wenqiu Hou, Rui Zhang, Daniel Zhang, Edward Zhang, Charlotte Hao, Xiaoke Xiong, Wenjun Zhang, Kang | 2017 | Cell Research2017，27，6： | 11 |
| 11 | An Imperfect-debugging Fault-detection Dependent-parameter Software显示文摘合并有瑕疵的调试和开发者的学习现象的软件可靠性生长模型(SRGM ) 最近被许多研究人员开发了估计象仍然是差错和软件可靠性的数字那样的软件可靠性措施。然而, SRGM 的察觉率功能经常是的差错内容率功能和差错的模型参数考虑了来自对方独立。在实践,这个假设不能是案例,调查是价值如果它不是,怎么办。在这篇论文,我们为如此的学习瞄准并且建议连接在二个函数之中的由一个普通参数的有瑕疵的调试和学习现象的一个软件可靠性模型,叫了有瑕疵调试的差错察觉依赖参数的模型。从真实应用程序收集的软件严峻的数据被利用为两个说明建议模型由决定非零的描述、预兆的力量起始的调试过程。关键词非同类的泊松过程 - 软件可靠性生长 - 最少的广场估计 - 预兆的力量 - 预兆比率的风险 Hoang Pham 在公牛从纽约的州立大学在工业工程从伊利诺大学, Urbana 平原,和硕士和博士学位在统计收到了硕士学位。他是有部门的大学生程序的一个教授和主席工业并且在 Rutgers 大学的系统工程, Piscataway,新泽西。在加入 Rutgers 前,他是有波音公司,西雅图,和设计实验室的爱达荷公民的一位高级工程专家,爱达荷下降。他是二本书的作者:软件可靠性(Springer-Verlag, 2000 ) 并且系统软件可靠性(Springer, 2006 ) ;这本书的合作者:可靠性和最佳的维护(Springer, 2006 ) ;可靠性工程的手册的编辑(Springer-Verlag, 2003 ) ;并且设计统计的手册(Springer, 2006 ) 在许多其它之中。他也是在可靠性工程的 Springer 系列的编辑并且出版了十体积的超过 90 篇杂志文章, 25 书章,和编辑。他是设计的可靠性,质量和安全的国际杂志的主编并且是几本杂志的一个编委成员。他是超过 25 个国际会议和专题讨论会的会议主席和程序主席,并且当前在设计是可靠性和质量上的第 13 国际会议的会议主席,西雅图, 2007。他是系统,人,和控制论上的 IEEE 交易的一个伙伴编辑。他的研究兴趣包括软件可靠性,当模特儿的系统可靠性,维护,和环境风险评价。 | Hoang Pham | 2007 | International Journal of Automation and computing2007，4，4： | 11 |
| 12 | 线性自抗扰控制在全桥DC–DC变换器中的应用显示文摘针对DC–DC变换器在实际应用中会受到多种输入扰动、负载扰动及电磁扰动影响的问题,本文结合全桥DC–DC变换器的系统模型特点,对传统线性自抗扰控制器进行了改进.设计了基于降阶扩张状态观测器和以比例控制作为误差反馈律的自抗扰控制器用于实际系统,在确保系统性能的前提下优化了参数整定过程.仿真和实验结果表明,该控制系统具有比传统PI控制系统更优的快速性、鲁棒性和适应性,且大大简化了传统自抗扰控制器设计过程中参数过多、取值困难的问题,具有良好的发展前景. | 王孝洪 吴丰 HOANG Thi Thu Giang 潘志锋 曾健华 | 2018 | 控制理论与应用2018，35，11： | 11 |
| 13 | DNA methyltransferases in hematological malignancies显示文摘DNA methyltransferases(DNMTs)are an evolutionarily conserved family of DNA methylases,transferring a methyl group onto the fifth carbon of a cytosine residue.The mammalian DNMT family includes three major members that have functional methylation activities,termed DNMT1,DNMT3A,and DNMT3B.DNMT3A and DNMT3B are responsible for methylation establishment,whereas DNMT1 maintains methylation during DNA replication.Accumulating evidence demonstrates that regulation of DNAmethylation by DNMTs is critical for normal hematopoiesis.Aberrant DNA methylation due to DNMT dysregulation and mutations is known as an important molecular event of hematological malignancies,such as DNMT3A mutations in acute myeloid leukemia.In this reviewwe first describe the basic methylation mechanisms of DNMTs and their functions in lymphocyte maturation and differentiation,We then discuss the current understanding of DNA methylation heterogeneity in leukemia and lymphoma to highlight the importance of studying DNA methylation targets.We also discuss DNMT mu-tations and pathogenic roles in human leukemia and lymphoma.We summarize the recent understanding of how DNMTs interact with transcription factors or cofactors to repress the expression of tumor suppressor genes.Firnally.we highlight current clinical studies using DNMT inhibitors for the treatment of these hematological malignancies. | Nguyet-Minh Hoang Lixin Rui | 2020 | Journal of Genetics and Genomics2020，47，7： | 10 |
| 14 | 我国南方水稻黑条矮缩病流行动态及预测预报实践显示文摘自2009年南方水稻黑条矮缩病在中国南方稻区局部首次暴发为害以来,在农业部的高度重视和支持下,全国农业技术推广服务中心组织全国植保体系系统开展病害的流行规律、调查监测和预测预报技术研究,初步掌握了病害的发生流行动态和特点,明确了影响我国南方稻区病害发生的毒源地主要为中南半岛的越南中北部及红河平原,其次为我国的海南和云南南部山区。2010年以来,制定了病害测报技术规范,建立了监测预警网络体系,积极开展预测预报工作。南方水稻黑条矮缩病的监测预报经历了由'恐慌'到'淡定'、由'心中无数'到'心中有数'、由'无所适从'到'有条不紊'的过程,病害预测的准确性明显提高,在有效指导防治、控制病害流行、减轻危害损失方面发挥了重要作用。 | 刘万才 陆明红 黄冲 周国辉 Hoang Anh Tuan | 2016 | 中国植保导刊2016，36，1： | 9 |
| 15 | 一种形态类似于黏液性平滑肌肉瘤的新型高级别子宫内膜间质肉瘤显示文摘子宫内膜间质肉瘤占子宫恶性肿瘤的1%,占子宫恶性间叶肿瘤的15%。WHO(2014)生殖肿瘤分类将子宫内膜间质肉瘤分为低级别子宫内膜间质肉瘤、高级别子宫内膜间质肉瘤及未分化子宫肉瘤。子宫内膜间质肉瘤常因频发染色体易位,致使发生参与表观遗传调控相关的基因融合。迄今为止,仅发现YWHAE-NUTM2重排与明确的高级别形态学及侵袭性临床行为密切相关。 | Hoang L N Aneja A Niamh C 黄爱清 余英豪 | 2017 | 临床与实验病理学杂志2017，33，7： | 9 |
| 16 | 越南水稻生产及其迁飞性害虫发生情况显示文摘介绍了越南水稻生产及其迁飞性害虫与病毒病发生为害情况,分析了中国与越南水稻迁飞性害虫的发生虫源关系,并就进一步明确我国水稻迁飞性害虫的主要虫源地及对我国的影响、迁飞发生规律提出了在深化与越南合作基础上,扩大与老挝、缅甸、柬埔寨等虫源地国家加强合作研究的建议。 | 刘万才 陆明红 翟保平 王建强 高小丽 Hoang Anh Tuan Ho Dang Cu | 2014 | 中国植保导刊2014，34，10： | 9 |
| 17 | Vitamin D deficiency and hepatitis viruses-associated liver diseases:a literature review显示文摘The secosteroid hormone vitamin D has, in addition to its effects in bone metabolism also functions in the modulation of immune responses against infectious agents and in inhibiting tumorigenesis. Thus, deficiency of vitamin D is associated with several malignancies, but also with a plethora of infectious diseases. Among other communicable diseases, vitamin D deficiency is involved in the pathogenesis of chronic liver diseases caused by hepatitis B and C viruses(HBV, HCV) and high prevalence of vitamin D deficiency with serum levels below 20 mg/mL in patients with HBV and HCV infection are found worldwide. Several studies have assessed the effects of vitamin D supplementation on the sustained virological response(SVR) to interferon(IFN) plus ribavirin(RBV) therapy in HBV and HCV infection. In these studies, inconsistent results were reported. This review addresses general aspects of vitamin D deficiency and, in particular, the significance of vitamin D hypovitaminosis in the outcome of HBVand HCV-related chronic liver diseases. Furthermore,current literature was reviewed in order to understand the effects of vitamin D supplementation in combination with IFN-based therapy on the virological response in HBV and HCV infected patients. | Nghiem Xuan Hoan Hoang Van Tong Le Huu Song Christian G Meyer Thirumalaisamy P Velavan | 2018 | World Journal of Gastroenterology2018，24，4： | 9 |
| 18 | Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection显示文摘AIM To investigate possible effects of IRF5 polymorphisms in the 3' UTR region of the IFR5 locus on susceptibilityto hepatitis B virus(HBV) infection and progression of liver diseases among clinically classified Vietnamese patients.METHODS Four IFR5 SNPs(rs13242262 A/T, rs77416878 C/T, rs10488630 A/G, and rs2280714 T/C) were genotyped in clinically classified HBV patients [chronic hepatitis B(CHB). n = 99; liver cirrhosis(LC), n = 131; hepatocellular carcinoma(HCC), n = 149] and in 242 healthy controls by direct sequencing and Taq Man realtime PCR assays. RESULTS Comparing patients and controls, no significant association was observed for the four IFR5 variants. However, the alleles rs13242262 T and rs10488630 G contributed to an increased risk of liver cirrhosis(LC vs CHB: OR = 1.5, 95%CI: 1.1-2.3, adjusted P = 0.04; LC vs CHB: OR = 1.7, 95%CI: 1.1-2.6, adjusted P = 0.019). Haplotype IRF5*TCGT constructed from 4 SNPs was observed frequently in LC compared to CHB patients(OR = 2.1, 95%CI: 1.2-3.3, adjusted P = 0.008). Haplotype IRF5*TCAT occurred rather among CHB patients than in the other HBV patient groups(LC vs CHB: OR = 0.4, 95%CI: 0.2-0.8, adjusted P = 0.03; HCC vs CHB: OR = 0.3, 95%CI: 0.15-0.7, adjusted P = 0.003). The IRF5*TCAT haplotype was also associated with increased levels of ALT, AST and bilirubin. CONCLUSION Our study shows that IFR5 variants may contribute as a host factor in determining the pathogenesis in chronic HBV infections. | Bui Tien Sy Nghiem Xuan Hoan Hoang Van Tong Christian G Meyer Nguyen Linh Toan Le Huu Song Claus-Thomas Bock Thirumalaisamy P Velavan | 2018 | World Journal of Gastroenterology2018，24，2： | 9 |
| 19 | Alumina-coated Ag nanocrystal monolayers as surfaceenhanced Raman spectroscopy platforms for the direct spectroscopic detection of water splitting reaction intermediates显示文摘 | Xing Yi Ling Ruoxue Yan Sylvia Lo Dat Tien Hoang Chong Liu Melissa A. Fardy Sher Bahadar Khan Abdullah M. Asiri Salem M. Bawaked Peidong Yang | 2014 | Nano Research2014，7，1： | 8 |
| 20 | Lung-protective Ventilation in Patients with Brain Injury: A Multicenter Cross-sectional Study and Questionnaire Survey in China显示文摘 | Xu-Ying Luo Ying-Hong Hu Xiang-Yuan Cao Yan Kang Li-Ping Liu Shou-Hong Wang Rong-Guo Yu Xiang-You Yu Xia Zhang Bao-Shan Li Zeng-Xiang Ma Yi-Bing Weng Heng Zhang De-Chang Chen Wei Chen Wen-Jin Chen Xiu-Mei Chen Bin Du Mei-Li Duan Jin Hu Yun-Feng Hoang Gui-Jun Jia Li-Hong Li Yu-Min Liang Bing-Yu Qin Xian-Dong Wang Jian Xiong Li-Mei Yan Zheng-Ping Yang Chen-Ming Dong Dong-Xin Wang Qing-Yuan Zhan Shuang-Lin FU Lin Zhao Qi-Bing Huang Ying-Guang Xie Xiao-Bo Huang Guo-Bin Zhang Wang-Bin Xu Yuan Xu YaLing Liu He-Ling Zhao Rong-Qing Sun Ming Sun Qing-Hong Cheng Xin Qu Xiao-Feng Yang Ming Xu Zhong-Hua Shi Han Chen Xuan He Yan-Lin Yang Guang-Qiang Chen Xiu-Mei Sun Jian-Xin Zhou | 2016 | Chinese Medical Journal2016，，14： | 6 |
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