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| 1 | Classification, Expression Pattern, and E3 Ligase Activity Assay of Rice U-Box-Containing Proteins显示文摘Ubiquitin ligases 玩在由为修正选择无数适当候选人蛋白质决定 ubiquitination 系统的特性的一个中央角色。U 盒子是一最近识别了,显示出更大的存在在的活动相关的蛋白质领域比在另外的有机体种的 ubiquitin ligase。在这研究,我们用一组整个染色体分析算法从米饭染色体识别了 77 通常认为的 U 盒子蛋白质。大多数 U 盒子蛋白质基因被表示,支持旁边他们的相应表示顺序标签(EST ) 的鉴定,全身的 cDNAs,或定序的大规模平行的签名(MPSS ) 标注。用一样的算法,我们从 Arabidopsis 染色体识别了 61 U 盒子蛋白质。米饭和 Arabidopsis U 盒子蛋白质基于他们的领域作文被分类进九个主要的班。在米饭和 Arabidopsis U 盒子蛋白质之间的比较显示米饭和 Arabidopsis U 盒子蛋白质的多数有一样的领域组织。推断的发展史建立了在米饭和 Arabidopsis U-box/ARM 蛋白质之间的相同。用米饭原物系统的房间死亡试金建议那一米饭 U 盒子基因, OsPUB51,可能充当房间死亡发信号的一个否定管理者。另外,选择 U 盒子蛋白质被发现是功能的 E3 ubiquitin ligases。在此,在 genomic,水平将机能上地帮助的米饭 U 盒子蛋白质的鉴定和分析以后描绘 E3 ubiquitin ligase 的这个班。 | Li-Rong Zenga Chan Ho Park R.C. Venu Julian Gough Guo-Liang Wang | 2008 | Molecular Plant2008，1，5： | 15 |
| 2 | Biliary strictures complicating living donor liver transplantation:Problems,novel insights and solutions显示文摘Biliary stricture complicating living donor liver transplantation(LDLT) is a relatively common complication, occurring in most transplant centres across the world. Cases of biliary strictures are more common in LDLT than in deceased donor liver transplantation. Endoscopic management is the mainstay for biliary strictures complicating LDLT and includes endoscopic retrograde cholangiography, sphincterotomy and stent placement(with or without balloon dilatation). The efficacy and safety profiles as well as outcomes of endoscopic management of biliary strictures complicating LDLT is an area that needs to be viewed in isolation, owing to its unique set of problems and attending complications; as such, it merits a tailored approach, which is yet to be well established. The diagnostic criteria applied to these strictures are not uniform and are over-reliant on imaging studies showing an anastomotic narrowing. It has to be kept in mind that in the setting of LDLT, a subjective anastomotic narrowing is present in most cases due to a mismatch in ductal diameters. However, whether this narrowing results in a functionally significant narrowing is a question that needs further study. In addition, wide variation in the endotherapy protocols practised in most centres makes it difficult to interpret the results and hampers our understanding of this topic. The outcome definition for endotherapy is also heterogenous and needs to be standardised to allow for comparison of data in this regard and establish a clinical practice guideline. There have been multiple studies in this area in the last 2 years, with novel findings that have provided solutions to some of these issues. This review endeavours to incorporate these new findings into the wider understanding of endotherapy for biliary strictures complicating LDLT, with specific emphasis on diagnosis of strictures in the LDLT setting, endotherapy protocols and outcome definitions. An attempt is made to present the best management options currently available as well as directions for future research in the area. | Harshavardhan B Rao Arjun Prakash Surendran Sudhindran Rama P Venu | 2018 | World Journal of Gastroenterology2018，24，19： | 14 |
| 3 | Endothelial progenitor cells as factors in neovascularization and endothelial repair显示文摘Endothelial progenitor cells(EPCs)are a heterogeneous population of cells that are provided by the bone marrow and other adult tissue in both animals and humans.They express both hematopoietic and endothelial surface markers,which challenge the classic dogma that the presumed differentiation of cells into angioblasts and subsequent endothelial and vascular differentiation occurred exclusively in embryonic development.This breakthrough stimulated research to understand the mechanism(s)underlying their physiologic function to allow development of new therapeutic options.One focus has been on their ability to form new vessels in injured tissues,and another has been on their ability to repair endothelial damage and restore both monolayer integrity and endothelial function in denuded vessels.Moreover,measures of their density have been shown to be a better predictor of cardiovascular events,both in healthy and coronary artery disease populations than the classical tools used in the clinic to evaluate the risk stratification.In the present paper we review the effects of EPCs on revascularization and endothelial repair in animal models and human studies,in an attempt to better understand their function,which may lead to potential advancement in clinical management. | Stefano Capobianco Venu Chennamaneni Mayank Mittal | 2010 | World Journal of Cardiology2010，2，12： | 7 |
| 4 | Function of flavonoids on different types of programmed cell death and its mechanism:a review显示文摘Cell death in the living system plays a vital role in maintaining the homeostasis and balancing the cell count in the body.Programmed cell death(PCD)is a crucial component of several development and defense mechanisms.PCD is also important in terms of aging which avoids the accumulation of cellular damage by maintaining cell division.Depending on the execution of cell death and its role in destruction,PCD is categorized into several subtypes.The major different forms of PCD in animals are apoptosis,autophagy and necrosis,which can be distinct in morphological terms.More intense investigations of cell death have given close insight showing other important types of cellular destruction and their pivotal roles in treating disease conditions like cancer.Flavonoids have been acquired a great interest for disease therapies and chemoprevention through activation of several PCD mechanisms.The significant potential of natural flavonoids in the induction of distinct signaling cascades is being a massive approach for targeting uncontrolled cell growth.For these reasons,understanding PCD mechanisms is a promising approach for the interventions in treating cancer.Thus,it is intriguing that understanding the different forms of PCD mechanism induced by flavonoids with more accurate descriptions on the biochemical and cellular processes are gaining more significance in cancer research.Here,we provide a brief overview on the different types of PCD and aim to discuss the functional role of flavonoids in promoting different types of cell death as well as an extensive brief review on their mechanism of action has been highlighted. | Preethi Vetrivel Seong Min Kim Venu Venkatarame Gowda Saralamma Sang Eun Ha Eun Hee Kim Tae Sun Min Gon Sup Kim | 2019 | The Journal of Biomedical Research2019，33，6： | 3 |
| 5 | Endoscopic therapy for biliary strictures complicating living donor liver transplantation: Factors predicting better outcome显示文摘AIM To identify factors predicting outcome of endoscopic therapy in bile duct strictures(BDS) post living donor liver transplantation(LDLT).METHODS Patients referred with BDS post LDLT, were retrospectively studied. Patient demographics, symptoms(Pruritus, Jaundice, cholangitis), intra-op variables(cold ischemia time, blood transfusions, number of ducts used, etc.), peri-op complications [hepatic artery thrombosis(HAT), bile leak, infections], stricture morphology(length, donor and recipient duct diameters) and relevant laboratory data both pre-and post-endotherapy were studied. Favourable response to endotherapy was defined as symptomatic relief with > 80% reduction in total bilirubin/serum gamma glutamyl transferase. Statistical analysis was performed using SPSS 20.0.RESULTS Forty-one patients were included(age: 8-63 years). All had right lobe LDLT with duct-to-duct anastomosis. Twenty patients(48.7%) had favourable response to endotherapy. Patients with single duct anastomosis, aggressive stent therapy(multiple endoscopic retrogradecholagiography, upsizing of stents, dilatation and longer duration of stents) and an initial favourable response to endotherapy were independent predictors of good outcome(P < 0.05). Older donor age, HAT, multiple ductal anastomosis and persistent bile leak(> 4 wk post LT) were found to be significant predictors of poor response on multivariate analysis(P < 0.05). CONCLUSION Endoscopic therapy with aggressive stent therapy especially in patients with single duct-to-duct anastomosis was associated with a better outcome. Multiple ductal anastomosis, older donor age, shorter duration of stent therapy, early bile leak and HAT were predictors of poor outcome with endotherapy in these patients. | Harshavardhan B Rao Hasim Ahamed Suprabha Panicker Surendran Sudhindran Rama P Venu | 2017 | World Journal of Gastrointestinal Pathophysiology2017，8，2： | 3 |
| 6 | Laboratory Diagnosis and Nonoperative Management of Biliary Complications in Living Donor Liver Transplant Patients显示文摘 | Mukund Venu Russell D. Brown Rita Lepe Jamie Berkes Scott J. Cotler Enrico Benedetti Giuliano Testa Rama P. Venu | 2007 | Journal of Clinical Gastroenterology2007，，5： | 2 |
| 7 | Optimal machining conditions for turning Ti-6Al-4V using response surface methodology显示文摘Machining titanium is one of ever-increasing magnitude problems due to its characteristics such as low thermal conductivity,modulus of elasticity and work hardening.The efficient titanium alloy machining involves a proper selection of process parameters to minimize the tangential force(F_z) and surface roughness(R_a).In the present work,the performance of PVD/TiAIN coated carbide inserts was investigated using response surface methodology(RSM) for turning Ti-6A1-4V.The effects of process parameters such as speed(v),feed(f),depth of cut(d) and back rake angle(γ_y) on F_z and R_a were investigated.The experimental plan used for four factors and three levels was designed based on face centered,central composite design(CCD).The experimental results indicated that F_z increased with the increase in d,f and decreased with the increase in v and γ_y,whereas R_a decreased with the increase in v and γ_y,and increased with d and v.The goodness of fit of the regression equations and model fits(R^2) for F_z and R_a were found to be 0.968and 0.970,which demonstrated that it was an effective model.A confirmation test was also conducted in order to verify the correctness of the model. | Satyanarayana Kosaraju Venu Gopal Anne | 2013 | Advances in Manufacturing2013，1，4： | 2 |
| 8 | Cardiopulmonary Resuscitation Quality: Improving Cardiac Resuscitation Outcomes Both Inside and Outside the Hospital: A Consensus Statement From the American Heart Association显示文摘 | Peter A. Meaney Bentley J. Bobrow Mary E. Mancini Jim Christenson Allan R. de Caen Farhan Bhanji Benjamin S. Abella Monica E. Kleinman Dana P. Edelson Robert A. Berg Tom P. Aufderheide Venu Menon Marion Leary | 2013 | Circulation2013，，4： | 2 |
| 9 | Stable structure of platinum carbides: A first principles investigation on the structure, elastic, electronic and phonon properties显示文摘 | Venu Mankad Nikita Rathod Sanjay D. Gupta Sanjeev K. Gupta Prafulla K. Jha | 2011 | Materials Chemistry and Physics2011，，3： | 1 |
| 10 | Micro-mechanical modeling of machining of FRP composites – Cutting force analysis显示文摘 | G. Venu Gopala Rao P. Mahajan N. Bhatnagar | 2006 | Composites Science and Technology2006，，3： | 1 |
| 11 | Biodiesel production from re- newable feedstocks: status and opportunities 显示文摘 | VENU B B VAIBHAV V G | 2012 | Renew Sustain Energy Rev2012，16，7： | 1 |
| 12 | Focused review:core strengthening显示文摘 | Venu A | 2004 | Arch Physi Med Rehabil2004，85，1： | 1 |
| 13 | Three-dimensional finite element modelling of a dog skull for the simulation of initial orthopaedic dis- placements显示文摘 | Venue V Dermaut L Verhegghe B | 2001 | Eur J Orthod2001，23，5： | 1 |
| 14 | Growth of ZrC thin films by aerosol-assisted MOCVD显示文摘 | Yong Sun Won Young Seok Kim Venu G. Varanasi Olga Kryliouk Timothy J. Anderson Chatu T. Sirimanne Lisa McElwee-White | 2007 | Journal of Crystal Growth2007，，2： | 1 |
| 15 | A minutia-based partial fingerprint recognition system 显示文摘 | Jea Tsai-Yang Venu Govindaraju | 2005 | Pattern Recognition2005，38，10： | 1 |
| 16 | Maternal dietary vitamin restriction increases body fat content but not insulin resistance in WNIN rat offspring up to 6 months of age显示文摘 | L. Venu N. Harishankar T. Prasanna Krishna M. Raghunath | 2004 | Diabetologia2004，，9： | 1 |
| 17 | Does maternal dietary mineral restriction per se predispose the offspring to insulin resistance 显示文摘 | VENU L HARISHANKAR N KRISHNA T P | 2004 | European Journal of Endocrinology2004，151，2： | 1 |
| 18 | Maternal and perinatal magnesium restriction predisposes rat pups to insulin resistance and glucose intolerance 显示文摘 | VENU L KISHORE Y D RAGHUNATH M | 2005 | The Journal of Nutrition2005，135，6： | 1 |
| 19 | Chronic maternal dietary chromium restriction modulates visceral adiposity: probable underlying mechanisms显示文摘 | PADMAVATHI I J RAO K R VENU L | 2010 | Diabetes2010，59，1： | 1 |
| 20 | Symmetric hash functions for secure fingerprint biometric systems显示文摘 | Sergey Tulyakov Faisal Farooq Praveer Mansukhani Venu Govindaraju | 2007 | Pattern Recognition Letters2007，，16： | 1 |
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