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| 1 | Improving Multimodel Weather Forecast of Monsoon Rain Over China Using FSU Superensemble显示文摘In this paper we present the current capabilities for numerical weather prediction of precipitation over China using a suite of ten multimodels and our superensemble based forecasts. Our suite of models includes the operational suite selected by NCARs TIGGE archives for the THORPEX Program. These are: ECMWF, UKMO, JMA, NCEP, CMA, CMC, BOM, MF, KMA and the CPTEC models. The superensemble strategy includes a training and a forecasts phase, for these the periods chosen for this study include the months February through September for the years 2007 and 2008. This paper addresses precipitation forecasts for the medium range i.e. Days 1 to 3 and extending out to Day 10 of forecasts using this suite of global models. For training and forecasts validations we have made use of an advanced TRMM satellite based rainfall product. We make use of standard metrics for forecast validations that include the RMS errors, spatial correlations and the equitable threat scores. The results of skill forecasts of precipitation clearly demonstrate that it is possible to obtain higher skills for precipitation forecasts for Days 1 through 3 of forecasts from the use of the multimodel superensemble as compared to the best model of this suite. Between Days 4 to 10 it is possible to have very high skills from the multimodel superensemble for the RMS error of precipitation. Those skills are shown for a global belt and especially over China. Phenomenologically this product was also found very useful for precipitation forecasts for the Onset of the South China Sea monsoon, the life cycle of the mei-yu rains and post typhoon landfall heavy rains and flood events. The higher skills of the multimodel superensemble make it a very useful product for such real time events. | T. N. KRISHNAMURTI A. D. SAGADEVAN A. CHAKRABORTY A. K. MISHRA A. SIMON | 2009 | Advances in Atmospheric Sciences2009，26，5： | 12 |
| 2 | Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress显示文摘AMPK, a master regulator of metabolic homeostasis, is activated by both AMP-dependent and AMP-independent mechanisms. The conditions under which these different mechanisms operate, and their biological implications are unclear. Here, we show that, depending on the degree of elevation of cellular AMP, distinct compartmentalized pools of AMPK are activated, phosphorylating different sets of targets. Low glucose activates AMPK exclusively through the AMP-independent, AXIN-based pathway in lysosomes to phosphorylate targets such as ACC1 and SREBP1c, exerting early anti-anabolic and pro-catabolic roles. Moderate increases in AMP expand this to activate cytosolic AMPK also in an AXIN-dependent manner. In contrast, high concentrations of AMP, arising from severe nutrient stress, activate all pools of AMPK independently of AXIN. Surprisingly, mitochondrion-localized AMPK is activated to phosphorylate ACC2 and mitochondrial fission factor (MFF) only during severe nutrient stress. Our findings reveal a spatiotemporal basis for hierarchical activation of different pools of AMPK during differing degrees of stress severity. | Yue Zong Chen-Song Zhang Mengqi Li Wen Wang Zhichao Wang Simon A. Hawley Teng Ma Jin-Wei Feng Xiao Tian Qu Qi Yu-Qing Wu Cixiong Zhang Zhiyun Ye Shu-Yong Lin Hai-Long Piao D. Grahame Hardie Sheng-Cai Lin | 2019 | Cell Research2019，29，6： | 8 |
| 3 | Inactivation of Mitochondrial Complex Ⅰ Induces the Expression of a Twin Cysteine Protein that Targets and Affects Cytosolic, Chloroplastidic and Mitochondrial Function显示文摘At12Cys-1 (At5g64400 ) 和 At12Cys-2 (At5g09570 ) 是二密切相关的 isogenes 编码小、成双的半胱氨酸蛋白质,典型地在线粒体定位了。At12Cys-2 抄本与破坏 mitochondrial 蛋白质,而是 At12Cys 的增加在许多异种被导致蛋白质仅仅与减少的 mitochondrial 在异种被检测复杂我丰富。在缺乏 mitochondrial 建筑群的异种的 At12Cys 蛋白质感应我被位于线粒体,叶绿体,和 cytosol 的 At12Cys 蛋白质伴随。生物化学的分析揭示了那甚至单个的基因删除,即, At12cys-1 或 At12cys-2,在 mitochondrial 和叶绿体功能上有效果。然而,仅仅加倍异种,即, At12cys-1 : At12cys-2,影响许多蛋白质和 mRNA 抄本编码翻译延伸因素以及 rRNA 丰富。蓝本国的页证明 At12Cys 与 mitochondrial supercomplex 共同移居我 + III。同样, At12cys-1 和 At12cys-2 基因的删除,然而并非单个基因删除,导致提高的忍耐到干旱和轻应力和增加的抗氧化剂能力。正式就职和在在建筑群的减小之上的 At12Cys 的多重本地化我丰富提供机制明确地表明 mitochondrial 机能障碍到 cytosol 然后在以外到在房间的另外的细胞器。 | Yan Wang Wenhui Lyu Oliver Berkowitz Jordan D. Radomiljac Simon R. Law Monika W. Murcha Chris Carrie Pedro F. Teixeira Beata Kmiec Owen Duncan Olivier Van Aken Reena Narsai Elzbieta Glaser Shaobai Huang Ute Roessner A. Harvey Millar James Whelan | 2016 | Molecular Plant2016，9，5： | 5 |
| 4 | Salt Stress Triggers Phosphorylation of the Arabidopsis Vacuolar K+ Channel TPK1 by Calcium-Dependent Protein Kinases (CDPKs)显示文摘 | Andreas Latz Norbert Mehlmer Simone Zapf Thomas D. Mueller Bernhard Wurzinger Barbara Pfister Edina Csaszar Rainer Hedrich Markus Teige Dirk Becker | 2013 | Molecular Plant2013，6，4： | 5 |
| 5 | Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association显示文摘 | Véronique L. Roger Alan S. Go Donald M. Lloyd-Jones Robert J. Adams Jarett D. Berry Todd M. Brown Mercedes R. Carnethon Shifan Dai Giovanni de Simone Earl S. Ford Caroline S. Fox Heather J. Fullerton Cathleen Gillespie Kurt J. Greenlund Susan M. Hailpern | 2011 | Circulation2011，，4： | 4 |
| 6 | Comparison of Leptosphaeria biglobosa-induced and chemically induced systemic resistance to L.maculans in Brassica napus显示文摘Brassica napus(cv.Madrigal)seedlings pre-treated with ascospores of Leptosphaeria biglobosa or foliar sprays of either acibenzolar-S-methyl(ASM)or menadione sodium bisulphite(MSB)were chal- lenge inoculated with L.maculans ascospores and assessed for phoma leaf spot development and tissue morphology and gene expression responses to infection.Rates of increase in phoma leaf spot area 8―21 d after challenge inoculation were significantly greater on water pre-treated plants than on plants pre-treated with L.biglobosa,ASM or MSB on both pre-treated leaves(local effect)and younger leaves without pre-treatment(systemic effect).Ninety-six h after challenge inoculation,the invasive hyphae of L.maculans were encircled by rings of necrotic mesophyll cells on leaves pre-treated with L. biglobosa,ASM or MSB but not those pre-treated with water.Quantification of transcript levels of genes commonly used as markers of the major defence signalling pathways(PDF1.2,PR-1,NPR1,APX, CHB4)0–96 h after L.maculans challenge inoculation showed expression patterns indicating prefer- ential activation of the jasmonate/ethylene pathway and involved induction of NPR1 locally and sys- temically in leaves of plants pre-treated with L.biglobosa ascospores. | LIU ShengYi LIU RenHu Akinwunmi O. LATUNDE-DADA Hans J. COOLS Simon J. FOSTER HUANG YongJu Bruce D. L. FITT | 2007 | Chinese Science Bulletin2007，52，8： | 4 |
| 7 | A new strategy for estimating risks of transfusion‐transmitted viral infections based on rates of detection of recently infected donors显示文摘 | Michael P.Busch Simone A.Glynn Susan L.Stramer D. MichaelStrong SallyCaglioti David J.Wright BrandeePappalardo Steven H.Kleinman | 2005 | Transfusion2005，，2： | 4 |
| 8 | Search for light vector boson production in e + e ? → μ + μ ? γ interactions with the KLOE experiment显示文摘 | D. Babusci I. Balwierz-Pytko G. Bencivenni C. Bloise F. Bossi P. Branchini A. Budano L. Caldeira Balkest?hl F. Ceradini P. Ciambrone F. Curciarello E. Czerwiński E. Danè V. De Leo E. De Lucia G. De Robertis A. De Santis P. De Simone A. Di Cicco A. Di Dome | 2014 | Physics Letters B2014，，： | 3 |
| 9 | No Effects of Gluten in Patients With Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of Fermentable, Poorly Absorbed, Short-Chain Carbohydrates显示文摘 | Jessica R. Biesiekierski Simone L. Peters Evan D. Newnham Ourania Rosella Jane G. Muir Peter R. Gibson | 2013 | Gastroenterology2013，，2： | 3 |
| 10 | 高血压患者左室向心性结构与舒张功能减退相关:HyperGEN研究 | De Simone G. Kitzman D. W. Chinali M. 郭战宏 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005，0，10： | 2 |
| 11 | Remote Ischemic Preconditioning by Hindlimb Occlusion Prevents Liver Ischemic/Reperfusion Injury: The Role of High Mobility Group-Box 1显示文摘 | Feng Wang Simone E. Birch Ruijan He Patrick Tawadros Katalin Szaszi Andras Kapus Ori D. Rotstein | 2010 | Annals of Surgery2010，，2： | 2 |
| 12 | Comparative Effectiveness for Survival and Renal Function of Partial and Radical Nephrectomy for Localized Renal Tumors: A Systematic Review and Meta-Analysis显示文摘 | Simon P. Kim R. Houston Thompson Stephen A. Boorjian Christopher J. Weight Leona C. Han M. Hassan Murad Nathan D. Shippee Patricia J. Erwin Brian A. Costello George K. Chow Bradley C. Leibovich | 2012 | The Journal of Urology2012，，： | 2 |
| 13 | The relationship of in vivo 31 P MR spectroscopy to histology in chronic hepatitis C显示文摘 | Adrian K.P. Lim Nayna Patel Gavin Hamilton Joseph V. Hajnal Robert D. Goldin Simon D. Taylor-Robinson | 2003 | Hepatology2003，，4： | 2 |
| 14 | Cardiovascular morbidity and mortality after orthotopic liver transplantation显示文摘 | Simon D. Johnston Joan K. Morris Rob Cramb Bridget K. Gunson James Neuberger | 2002 | Transplantation2002，，6： | 2 |
| 15 | Rising trends in cholangiocarcinoma: Is the ICD classification system misleading us?显示文摘 | Shahid A. Khan Shireen Emadossadaty Nimzing G. Ladep Howard C. Thomas Paul Elliott Simon D. Taylor-Robinson Mireille B. Toledano | 2011 | Journal of Hepatology2011，，4： | 2 |
| 16 | Omega‐3 fatty acids and/or fluvastatin in hepatitis C prior non‐responders to combination antiviral therapy – a pilot randomised clinical trial显示文摘 | David A. Sheridan Simon H. Bridge Mary M. E. Crossey Daniel J. Felmlee Fiona I. Fenwick Howard C. Thomas R. Dermot G. Neely Simon D. Taylor‐Robinson Margaret F. Bassendine | 2014 | Liver Int2014，，5： | 2 |
| 17 | Use of Octogenarian Donors for Liver Transplantation: A Survival Analysis显示文摘 | D. Ghinolfi J. Marti P. De Simone Q. Lai D. Pezzati L. Coletti D. Tartaglia G. Catalano G. Tincani P. Carrai D. Campani M. Miccoli G. Biancofiore F. Filipponi | 2014 | American Journal of Transplantation2014，，9： | 2 |
| 18 | GP73, a novel Golgi-localized protein upregulated by viral infection显示文摘 | Raleigh D. Kladney Gary A. Bulla Linsheng Guo Andrew L. Mason Ann E. Tollefson Daniela J. Simon Zaher Koutoubi Claus J. Fimmel | 2000 | Gene2000，，1： | 2 |
| 19 | Evaluating hyperspectral vegetation indices for estimating nitrogen concentration of winter wheat at different growth stages显示文摘 | Fei Li Yuxin Miao Simon D. Hennig Martin L. Gnyp Xinping Chen Liangliang Jia Georg Bareth | 2010 | Precision Agriculture2010，，4： | 2 |
| 20 | Farmer Participatory Evaluation of Nursery Bed Treatments for the Control of Root-Knot Nematodes [Meloidogynejavanica (Treub) Chitwood and Meloidogyne incognita (Kofoid and White) Chitwood] in Smallholder Farms in Kenya显示文摘 | D. K. Karanja S. R. Gowen B. Ndung u R. O. Musebe S. Simons A McLeod B. R. Kerry P. K. Karanja B. Pembroke | 2011 | Journal of Agricultural Science and Technology(A)2011，1，5： | 2 |
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