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| 1 | Acute kidney injury and post-reperfusion syndrome in liver transplantation显示文摘In the past decades liver transplantation(LT) has become the treatment of choice for patients with end stage liver disease(ESLD). The chronic shortage of cadaveric organs for transplantation led to the utilization of a greater number of marginal donors such as older donors or donors after circulatory death(DCD). The improved survival of transplanted patients has increased the frequency of long-term complications, in particular chronic kidney disease(CKD). Acute kidney injury(AKI) post-LT has been recently recognized as an important risk factor for the occurrence of denovo CKD in the long-term outcome. The onset of AKI post-LT is multifactorial, with pre-LT risk factors involved, including higher Model for End-stage Liver Disease score, more sever ESLD and pre-existing renal dysfunction, either with intra-operative conditions, in particular ischaemia reperfusion injury responsible for post-reperfusion syndrome(PRS) that can influence recipient's morbidity and mortality. Post-reperfusion syndrome-induced AKI is an important complication post-LT that characterizes kidney involvement caused by PRS with mechanisms not clearly understood and implication on graft and patient survival. Since preLT risk factors may influence intra-operative events responsible for PRS-induced AKI, we aim to consider all the relevant aspects involved in PRS-induced AKI in the setting of LT and to identify all studies that better clarified the specific mechanisms linking PRS and AKI. A Pub Med search was conducted using the terms liver transplantation AND acute kidney injury; liver transplantation AND post-reperfusion syndrome; acute kidney injury AND post-reperfusion syndrome; acute kidney injury AND DCD AND liver transplantation. Five hundred seventy four articles were retrieved on Pub Med search. Results were limited to title/abstract of English-language articles published between 2000 and 2015. Twenty-three studies were identified that specifically evaluated incidence, risk factors and outcome for patients developing PRS-induced AKI in liver transplantation. In order to identify intra-operative risk factors/mechanisms specifically involved in PRSinduced AKI, avoiding confounding factors, we have limited our study to 'acute kidney injury AND DCD AND liver transplantation'. Accordingly, three out of five studies were selected for our purpose. | Ilaria Umbro Francesca Tinti Irene Scalera Felicity Evison Bridget Gunson Adnan Sharif James Ferguson Paolo Muiesan Anna Paola Mitterhofer | 2016 | World Journal of Gastroenterology2016，22，42： | 16 |
| 2 | Cardiovascular morbidity and mortality after orthotopic liver transplantation显示文摘 | Simon D. Johnston Joan K. Morris Rob Cramb Bridget K. Gunson James Neuberger | 2002 | Transplantation2002，，6： | 2 |
| 3 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016，22，45： | 2 |
| 4 | Does the Banff rejection activity index predict outcome in patients with early acute cellular rejection following liver transplantation?显示文摘 | Horoldt BS Burattin M Gunson BK | 2006 | Liver Transpl2006，12，7： | 1 |
| 5 | Liver transplantation:changing goals in immunosuppression显示文摘 | McMaster P Gunson B Min X | 1998 | Transplant Proc1998，30，5： | 1 |
| 6 | Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large US community显示文摘 | Chugh SS Jui J Gunson K | 2004 | Journal of the American College of Cardiology2004，44，6： | 1 |
| 7 | Delayed hepatic artery thrombosis in adult orthotopic liver transplantation-a 12-year experience显示文摘 | Bhattacharjya S Gunson BK Mirza DF | 2001 | Transplantation2001，71，11： | 1 |
| 8 | The development of a multiplex real - time PCR for the detection of herpes simplex virus 1 and 2, varizella zoster virus, adenovirus and chlamydia tracho- matis from eye swabs显示文摘 | Bennett S Carman W F Gunson R N | 2013 | J Virol Methods2013，189，1： | 1 |
| 9 | Influence of ischemia- reperfusion injury on rejection after liver transplantation 显示文摘 | Pirenne J Gunson B Khaleef H | 1997 | Transplant Proc1997，29，12： | 1 |
| 10 | Portal vein thrombosis in adults undergoing liver transplantation:risk factors,screening, management,and outcome 显示文摘 | Yerdel MA Gunson B Mirza D | 2000 | Transplantation2000，69，6： | 1 |
| 11 | Curtin industrial safety trial:Managerial behavior and program effectiveness 显示文摘 | Harper A C Cordery J L De Klerk N H Sevastos P Geelhoed E Gunson C Robinson L Sutherland M Osbom D Colquhoun J | 1996 | Safety Science1996，24，3： | 1 |
| 12 | PORTAL VEIN THROMBOSIS IN ADULTS UNDERGOING LIVER TRANSPLANTATION : Risk Factors, Screening, Management, and Outcome1显示文摘 | Mehmet Ali Yerdel Bridget Gunson Darius Mirza Kaan Karayal?in Simon Olliff John Buckels David Mayer Paul McMaster Jacques Pirenne | 2000 | Transplantation2000，，9： | 1 |
| 13 | An apple a day: the influence of memory on consumer judgment of quality 显示文摘 | Harker F R Gunson F A Brookfield P L | 2002 | Food Quality Preference2002，13，3： | 1 |
| 14 | Oral contraceptive pill use and abnormal menstrual cycles in women with severe condylar resorption: a case for low serum 17 beta-estradiol as a major factor in progressive condylar resorption 显示文摘 | Gunson MJ Arnett GW Formby B | 2009 | Am J Orthod Dentofacial Orthop2009，136，6： | 1 |
| 15 | The real-time detection of sapovirus显示文摘 | GUNSON R N COLLINS T C CARMAN W F | 2006 | J ClinVirol2006，35，3： | 1 |
| 16 | Impact of donor age and year of transplantation on graft and patient survival following liver transplantation for hepatitis C virus显示文摘 | Mutimer DJ Gunson B Chen J | 2006 | Transplantation2006，81，1： | 1 |
| 17 | Oral contraceptive pill use and abnormal menstrual cycles in women with severe condylar resorption: a case for low serum 17β-estradiol as a major factor in progressive condylar resorption 显示文摘 | Gunson MJ Arnett G W Formby B | 2009 | Am J Orthod Dentofacial Orthop2009，136，6： | 1 |
| 18 | Development of a real- time RT PCR for the detection of swlne-lineage Influenza A (H1N1) virus infections显示文摘 | Can MJ Gunson R Maclean A | 2009 | J Clin Virol2009，45，3： | 1 |
| 19 | Delayed hepatic artery thrombosis in adult orthotopic liver transplantation: a 12-year experience显示文摘 | Bhattacharjya S Gunson BK Mirza DF | 2001 | Transplantation2001，71，11： | 1 |
| 20 | Steroid with drawal from long term immunosuppression in liver allografts recipients显示文摘 | Padbury RTA Gunson BK Dousset B | 1993 | Transplantation1993，55，4： | 1 |
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