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| 1 | Extraocular retinoblastoma in Indian children:clinical,imaging and histopathological features显示文摘AIM:To study eyes with extraocular dissemination(EORB),with the following aims:first to establish the mean lag period and to understand various reasons for delayed presentation,second to study their imaging profiles and third to analyze histopathological features of eyes enucleated after neoadjuvant chemotherapy.·METHODS:Prospective study of clinical and imaging features of EORBs(stage Ⅲ and Ⅳ International Retinoblastoma Staging System) presenting to a tertiary eye care centre.Histopathological features of eyes enucleated after receiving neoadjuvant chemotherapy were analyzed.A pictorial illustration of the varied imaging profile of EORB was also presented.·RESULTS:Over a period of one year,97 eyes were diagnosed with retinoblastoma;32 children(36 eyes)(37.1%) had EORB.Mean age 3.6±1.9 years,71.9% males,71.9% unilateral,3.1% with positive family history and40.6% with metastasis.On imaging,there was extrascleral involvement in 22.2%,involvement of orbital part of optic nerve in 33.3%,involvement of central nervous system in 27.8% and orbital wall involvement in2.9% eyes.On histopathological analysis of eyesenucleated after neoadjuvant chemotherapy,25.0% had no residual viable tumour tissue and rest all tumours were poorly differentiated.·CONCLUSION:There are very few human malignancies where definitive treatment is started without any confirmed histopathological diagnosis and imaging plays an important role in diagnosis and appropriate staging of the disease.Chemotherapy has a variable effect on EORB,75.0% of eyes with EORB had residual viable tumour tissue when enucleated after receiving neoadjuvant chemotherapy. | Sumita Sethi Neelam Pushker Seema Kashyap Sanjay Sharma Mridula Mehta Sameer Bakhshi Saurbhi Khurana Supriyo Ghose | 2013 | International Journal of Ophthalmology(English edition)2013,6,4: | 5 |
| 2 | Sleep apnoea and stroke显示文摘Sleep disorders have been known to physicians for a long time.In his famous aphorisms,Hippocrates said“Sleep or watchfulness exceeding that which is customary,augurs unfavorably”.Modern medicine has been able to disentangle some of the phenomena that disturb sleep.Among the most notable offenders is sleep apnoea that has gained prominence in the past few decades.It is being proposed as one of the potentially modifiable risk factors for vascular diseases including stroke.The pathological mechanisms linking sleep apnoea to vascular risk factors include hypoxia,cardiac arrhythmias,dysautonomia,impaired glucose tolerance,hypertension,dyslipidaemia and inflammation.In this article,we review literature linking sleep apnoea and stroke,including sleep apnoea as a risk factor for primary prevention with the potential to improve outcome after acute stroke and as a secondary risk factor,amenable to modification and hence vascular risk reduction. | Sameer Sharma Antonio Culebras | 2016 | Stroke & Vascular Neurology2016,1,4: | 4 |
| 3 | Coexistence of pneumothorax and chilaiditi sign:A case report显示文摘We present a case of 50 year old male patient with coexistence of Pneumothorax and Chilaiditi sign.Chilaiditi sign is an incidental radiographic finding of a usually asymptomatic condition in which a part of intestine is located between the liver and diaphragm;however,the term'Chilaiditi syndrome'is used for symptomatic hepatodiaphragmatic interposition.The patient had no symptoms of abdominal pain,constipation,diarrhea,or emesis.Incidentally,Chilaiditi sign was diagnosed on chest radiography.Pneumothorax is defined as air in the pleural space.Pneumothoraces are classified as spontaneous or traumatic.Spontaneous pneumothorax is labelled as primary when no underlying lung disease is present,or secondary,when it is associated with pre-existing lung disease.Our case is the rare in the literature indicating the coexistence of Chilaiditi sign and pneumothorax. | Tangri Nitin Singhal Sameer Sharma Priyanka Mehta Dinesh Bansal Sachin Bhushan Neeraj Singla Sulbha Singh Puneet | 2014 | Asian Pacific Journal of Tropical Biomedicine2014,4,1: | 2 |
| 4 | C-reactive protein predicts long-term mortality independently of low-density lipoprotein cholesterol in patients undergoing percutaneous coronary intervention显示文摘 | Louai Razzouk Paul Muntner Sameer Bansilal Annapoorna S. Kini Ashish Aneja Joshua Mozes Oana Ivan Madhavi Jakkula Samin Sharma Michael E. Farkouh | 2009 | American Heart Journal2009,,2: | 1 |
| 5 | Endoscopic Sclerotherapy of Gastric Variceal Bleeding with N-Butyl-2-Cyanoacrylate显示文摘 | Radha K. Dhiman Yogesh Chawla Sameer Taneja Rakesh Biswas Tilak R. Sharma Jang B. Dilawari | 2002 | Journal of Clinical Gastroenterology2002,,3: | 1 |
| 6 | Adsorption of Meloxicam on Porous Calcium Silicate: Characterization and Tablet Formulation 显示文摘 | Sameer Sharma Praveen Sher Shraddha Badve | 2005 | AAPS PharmSciTech2005,6,4: | 1 |
| 7 | Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain显示文摘 | Sameer Sharma Srinivas K Kulkarni | 2006 | European Journal of Pharmacology2006,536,: | 1 |
| 8 | Outcome, Pathologic Findings, and Compliance in Orbital Retinoblastoma (International Retinoblastoma Staging System Stage III) Treated with Neoadjuvant Chemotherapy显示文摘 | Venkatraman Radhakrishnan Seema Kashyap Neelam Pushker Sanjay Sharma Sushmita Pathy Bidhu K. Mohanti Sreenivas Vishnubhatla Supriyo Ghose Sameer Bakhshi | 2012 | Ophthalmology2012,,7: | 1 |
| 9 | Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model显示文摘 | Amit Gupta Garima Vij Sameer Sharma Naveen Tirkey Praveen Rishi Kanwaljit Chopra | 2008 | Immunobiology2008,,1: | 1 |
| 10 | Epigenetic alterations of CDH1 and APC genes: Relationship with activation of Wnt/β-catenin Pathway in invasive ductal carcinoma of breast显示文摘 | Chandra P. Prasad Sameer Mirza Gayatri Sharma Rajinder Prashad Siddhartha DattaGupta Gayatri Rath Ranju Ralhan | 2008 | Life Sciences2008,,9: | 1 |
| 11 | Studies of air quality predictors based on neural networks显示文摘 | SHARMA SAMEER BARAI S V DIKSHIT A K | 2003 | International Journal of Environment and Pollution2003,19,5: | 1 |
| 12 | Unusual presentation of Erdheim-Chester disease in a child with acute lymphoblastic leukemia显示文摘Erdheim-Chester disease(ECD) is an uncommon, nonfamilial, non-Langerhans cell histiocytosis, which involves skeletal system and soft tissue usually in middle aged and elderly patients. The characteristic radiologic features include bilateral, symmetric cortical osteosclerosis of the diaphyseal and metaphyseal parts of the long bones, or bilateral symmetrically abnormal intense 99 mTechnetium labelling of the metaphyseal-diaphyseal region of the long bones, and computed tomography scan findings of 'coated aorta' or 'hairy kidneys'. ECD in childhood with osteolytic lesion is extremely rare. We describe an unusual case with an expansile lytic bone lesion at presentation in a case of acute lymphoblastic leukemia. | Archana George Vallonthaiel Asit Ranjan Mridha Shivanand Gamanagatti Manisha Jana Mehar Chand Sharma Shah Alam Khan Sameer Bakhshi | 2016 | World Journal of Radiology2016,8,8: | 1 |
| 13 | Hesperidin blunts streptozotocin-isoproternol induced myocardial toxicity in rats by altering of PPAR-γ receptor显示文摘 | Yogeeta O. Agrawal Pankaj Kumar Sharma Birendra Shrivastava Dharamvir Singh Arya Sameer N. Goyal | 2014 | Chemico-Biological Interactions2014,,: | 1 |
| 14 | Lingual Mucosal Graft Urethroplasty for Anterior Urethral Strictures显示文摘 | Suren K. Das Abhay Kumar Girish K. Sharma Ashwani K. Pandey Harbans Bansal Sameer Trivedi Udai S. Dwivedi Visweswar Bhattacharya Pratap B. Singh | 2009 | Urology2009,,1: | 1 |
| 15 | Clin-ical significance of Stratifin,ERa and PR promoter methylation in tumor and serum DNA in Indian breast cancer patients显示文摘 | Sameer Mirza Gayatri Sharma Rajinder Parshad | 2010 | Clinical Biochemistry2010,43,45: | 1 |
| 16 | Early Results of Core Decompression and Autologous Bone Marrow Mononuclear Cells Instillation in Femoral Head Osteonecrosis显示文摘 | Ramesh Kumar Sen Sujit Kumar Tripathy Sameer Aggarwal Neelam Marwaha Ratti Ram Sharma Niranjan Khandelwal | 2012 | The Journal of Arthroplasty2012,,5: | 1 |
| 17 | Comparison of health-related quality of life of children during maintenance therapy with acute lymphoblastic leukemia versus siblings and healthy children in India显示文摘 | Minakshi Bansal Kamlesh K. Sharma Manju Vatsa Sameer Bakhshi | 2013 | Leukemia & Lymphoma2013,,: | 1 |
| 18 | Extraarticular bony ankylosis in a child with supracondy- lar fracture of humerus显示文摘肌炎 ossificans 在受伤肌肉的地点被定义为骨头的形成。它是在孩子的肱骨的 supracondylar 骨折的稀罕复杂并发症之一。肌炎质量通常在 brachialis 肌肉在前面的方面上发展并且生产运动,而是完全的关节僵硬的范围的限制是稀罕的。就我们的知识而言,这是作为肌炎 ossificans traumatica 的后果在文学要报导的第一个案例。在这种情况中,一个六岁的孩子在正确的肘疼痛地介绍了给急诊室在以后一 fall on 伸出了手在玩期间。在通过前面的途径的外科的切除以后,孩子没最后与进一步无痛苦的屈曲有对肘和 15 度的剩余屈曲畸形可参考的症状直到 100 度在外科以后的一年的后续。 | Sameer Naranje Ramprasad Kancherla Arun Kannan Rajesh Malhotra Lalit Sharma Sukesh Rao Sankineani | 2012 | Chinese Journal of Traumatology2012,15,5: | 0 |
| 19 | Effect of Ferroelectric Nanopowder on Electrical and Acoustical Properties of Cholesteric Liquid Crystal显示文摘The composite materials based on nanopowder dispersed liquid crystals are important both from fundamental research and device applications due to their unique properties such as improvement in various properties like electrical,optical,thermal,energy storage and spontaneous polarization etc.The proper selection of nanoparticle and its size which to be dispersed in particular liquid crystals is very important for a particular application.In the present study,a ferroelectric nanopowder of Barium Titanate(BaTiO3)was dispersed in cholesteric liquid crystal and the same was confirmed by Fourier Transform Infrared(FTIR)Spectroscopy.The various acoustical properties like ultrasonic velocity,density,Adiabatic Compressibility,Rao Constant,Wada Constant and Acoustic Impedance were investigated by ultrasonic interferometer at room temperature at fixed frequency.The dielectric constant was determined by Precision Impedance Analyzer.In addition to these investigations,particle size and surface area were also measured.Our investigation shows enhanced in dielectric and acoustical properties which may be useful for device applications extensively in microelectronics,low cost-photovoltaic devices,and custom-shaped containers possibly applied as a coating. | Santosh Mani Madhavi Pradhan Archana Sharma SRChawade Sameer Hadkar Krishnakant Mishra Jyoti Amare Pradip Sarawade | 2020 | Non-Metallic Material Science2020,2,1: | 0 |
| 20 | Nonselective beta‐blockers reduce mortality in patients with acute‐on‐chronic liver failure显示文摘Aim:Nonselective beta‐blockers(NSBBs)can reduce the incidence of complications in patients with cirrhosis and prolong survival.The safety and efficacy of NSBBs in real‐world settings in patients with acute‐on‐chronic liver failure(ACLF)identified by the Asian Pacific Association for the Study of Liver criteria are unknown.This study aimed to assess the safety and efficacy of NSBBs in patients with Asian Pacific Association for the Study of Liver(APASL)‐defined ACLF Methods:In this retrospective,multicenter study,patients with ACLF with complete 30 days follow‐up from January 2019 to December 2021 were included.The primary objective was to compare 30‐day mortality among standard of care(SOC)and NSBB(+SOC)groups.The secondary objectives were to compare the incidence of infection,variceal bleed,and recompensation among both the groups.Results:A total of 346 patients were included.Only 26%(n=89)of them received NSBBs,while 74%(n=257)received only SOC.On Kaplan-Meier analysis,the incidence of mortality was 21%(95%confidence interval[CI]:16.20-26.50)in SOC group compared to only 8%(95%CI:3.22-15.53)in NSBB group at Day 30(p=0.005).Similarly,mortality in SOC group was 63%(95%CI:56.81-69.00)compared to 46%(95%CI:35.44-57.00)in NSBB group at 1 year(p=0.001).NSBB therapy could not reduce the incidence of infections or variceal bleed.Forty‐seven percent of patients in the SOC group and 73%of patients in the NSBB group(p<0.001)recompensated.Carvedilol was prescribed in 77.5%and propranolol in 22.5%of patients.Conclusions:NSBBs reduce mortality without any effect on infection or variceal bleed in patients with ACLF.However,only one in four ACLF patients are suitable for NSBB therapy. | Anand V.Kulkarni Madhumita Premkumar Karan Kumar Juned A.Khan Baqar A.Gora Sowmya Tirumalle Sameer Shaik Mithun Sharma Rajesh Gupta Nageshwar D.Reddy Padaki N.Rao | 2022 | Portal Hypertension & Cirrhosis2022,1,1: | 0 |