|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prognostic significance of red blood cell distribution width in gastrointestinal disorders显示文摘The red blood cell distribution width(RDW) is a routinely measured and automatically reported blood parameter,which reflects the degree of anisocytosis. Recently,the baseline RDW was found to have clinical significance for assessing clinical outcome and severity of various pathological conditions including cardiovascular diseases,sepsis,cancers,leukemia,renal dysfunction and respiratory diseases. A myriad of factors,most of which ill-defined,have an impact on the red cell population dynamics(i.e.,production,maturation and turnover). A delay in the red blood cell clearance in pathological conditions represents one of the leading determinants of increased anisocytosis. Further study of RDW may reveal new insight into inflammation mechanisms. In this review,we specifically discuss the current literature about the association of RDW in various disease conditions involving the gastrointestinal and hepatobiliary systems. We also present some of the related measurements for their value in predicting clinical outcomes in such conditions. According to our data,RDW was found to be a valuable prognostic index in gastrointestinal disorders along with additional inflammatory biomarkers(i.e.,C reactive protein,erythrocyte sedimentation rate,and platelet count) and current disease severity indices used in clinical practice. | Hemant Goyal Giuseppe Lippi Altin Gjymishka Bijo John Rajiv Chhabra Elizabeth May | 2017 | World Journal of Gastroenterology2017，23，27： | 20 |
| 2 | Complications in the management of closed high-energy proximal tibial plateau fractures显示文摘 | Kavin Khatri Vijay Sharma Darsh Goyal Kamran Farooque | 2016 | Chinese Journal of Traumatology2016，19，6： | 18 |
| 3 | Atrial fibrillation in obstructive sleep apnea显示文摘Atrial fibrillation(AF) is a common arrhythmia with rising incidence.Obstructive sleep apnea(OSA) is prevalent among patients with AF.This observation has prompted significant research in understanding the relationship between OSA and AF.Multiple studies support a role of OSA in the initiation and progression of AF.This association has been independent of obesity,body mass index and hypertension.Instability of autonomic tone and wide swings in intrathoracic pressure are seen in OSA.These have been mechanistically linked to initiation of AF in OSA patients by lowering atrial effective refractory period,promoting pulmonary vein discharges and atrial dilation.OSA not only promotes initiation of AF but also makes management of AF difficult.Drug therapy and electrical cardioversion for AF are less successful in presence of OSA.There has been higher rate of early and overall recurrence after catheter ablation of AF in patients with OSA.Treatment of OSA with continuous positive airway pressure has been shown to improve control of AF.However,additional studies are needed to establish a stronger relationship between OSA treatment and success ofAF therapies.There should be heightened suspicion of OSA in patients with AF.There is a need for guidelines to screen for OSA as a part of AF management. | Sandeep K Goyal Abhishek Sharma | 2013 | World Journal of Cardiology2013，5，6： | 16 |
| 4 | Testing the pecking order theory of capital structure显示文摘 | Murray Z Frank Vidhan K Goyal | 2002 | Journal of Financial Economics2002，，2： | 10 |
| 5 | Comparative prospective study between medial and lateral distal tibial locking compression plates for distal third tibial fractures显示文摘 | Sandeep Garg Vikram Khanna Mahaveer Prashad Goyal Narendra Joshi Amrut Borade Ishan Ghuse | 2017 | Chinese Journal of Traumatology2017，20，3： | 8 |
| 6 | Lessons learned from an audit of 1250 anal fistula patients operated at a single center:A retrospective review显示文摘BACKGROUND A complex anal fistula is a challenging disease to manage.AIM To review the experience and insights gained in treating a large cohort of patients at an exclusive fistula center.METHODS Anal fistulas operated on by a single surgeon over 14 years were analyzed.Preoperative magnetic resonance imaging was done in all patients.Four procedures were performed:fistulotomy;two novel sphincter-saving procedures,proximal superficial cauterization of the internal opening and regular emptying and curettage of fistula tracts(PERFACT)and transanal opening of intersphincteric space(TROPIS),and anal fistula plug.PERFACT was initiated before TROPIS.As per the institutional GFRI algorithm,fistulotomy was done in simple fistulas,and TROPIS was done in complex fistulas.Fistulas with associated abscesses were treated by definitive surgery.Incontinence was evaluated objectively by Vaizey incontinence scores.RESULTS A total of 1351 anal fistula operations were performed in 1250 patients.The overall fistula healing rate was 19.4%in anal fistula plug(n=56),50.3%in PERFACT(n=175),86%in TROPIS(n=408),and 98.6%in fistulotomy(n=611)patients.Continence did not change significantly after surgery in any group.As per the new algorithm,1019 patients were operated with either the fistulotomy or TROPIS procedure.The overall success rate was 93.5%in those patients.In a subgroup analysis,the overall healing rate in supralevator,horseshoe,and fistulas with an associated abscess was 82%,85.8%,and 90.6%,respectively.The 90.6%healing rate in fistulas with an associated abscess was comparable to that of fistulas with no abscess(94.5%,P=0.057,not significant).CONCLUSION Fistulotomy had a high 98.6%healing rate in simple fistulas without deterioration of continence if the patient selection was done judiciously.The sphincter-sparing procedure,TROPIS,was safe,with a satisfactory 86%healing rate for complex fistulas.This is the largest anal fistula series to date. | Pankaj Garg Baljit Kaur Ankita Goyal Vipul D Yagnik Sushil Dawka Geetha R Menon | 2021 | World Journal of Gastrointestinal Surgery2021，13，4： | 8 |
| 7 | Lesion-symptom mapping with NIHSS sub-scores in ischemic stroke patients显示文摘Background Lesion-symptom mapping(LSM)is a statistical technique to investigate the population-specific relationship between structural integrity and post-stroke clinical outcome.In clinical practice,patients are commonly evaluated using the National Institutes of Health Stroke Scale(NIHSS),an 11-domain clinical score to quantitate neurological deficits due to stroke.So far,LSM studies have mostly used the total NIHSS score for analysis,which might not uncover subtle structure–function relationships associated with the specific sub-domains of the NIHSS evaluation.Thus,the aim of this work was to investigate the feasibility to perform LSM analyses with sub-score information to reveal category-specific structure–function relationships that a total score may not reveal.Methods Employing a multivariate technique,LSM analyses were conducted using a sample of 180 patients with NIHSS assessment at 48-hour post-stroke from the ESCAPE trial.The NIHSS domains were grouped into six categories using two schemes.LSM was conducted for each category of the two groupings and the total NIHSS score.Results Sub-score LSMs not only identify most of the brain regions that are identified as critical by the total NIHSS score but also reveal additional brain regions critical to each function category of the NIHSS assessment without requiring extensive,specialised assessments.Conclusion These findings show that widely available sub-scores of clinical outcome assessments can be used to investigate more specific structure–function relationships,which may improve predictive modelling of stroke outcomes in the context of modern clinical stroke assessments and neuroimaging. | Deepthi Rajashekar Matthias Wilms M Ethan MacDonald Serena Schimert Michael D Hill Andrew Demchuk Mayank Goyal Sean P Dukelow Nils Daniel Forkert | 2022 | Stroke & Vascular Neurology2022，7，2： | 7 |
| 8 | Posterior dislocation of the hip with ipsilateral displaced femoral neck fracture显示文摘与 ipsilateral 联系的臀部的创伤的以后的脱臼代替了大腿骨的颈骨折是稀罕损害。而且,如此的病人的管理唤起考虑主要代替或保存大腿骨的头的强壮的看法。我们与如此的损害介绍了年轻成年人的一个盒子。他被操作在之上与大腿骨的颈的脱臼和固定的减小,在 cancellous 的帮助下的骨折拧紧。二年以后,破裂联合起来,病人是无征状的。我们进一步为如此的破裂建议了损害的机制并且在发展中的世界的变化损伤情形讨论了管理。 | Vivek Trikha Tarun Goyal Ram K. Jha | 2011 | Chinese Journal of Traumatology2011，14，2： | 6 |
| 9 | 艾氏天芥菜对顺铂引起的小鼠肾损伤的保护作用(英文)显示文摘目的:该研究旨在评估紫草科药材艾氏天芥菜的甲醇提取物对于顺铂导致小鼠急性肾损伤的保护作用。方法:用腹膜内注射顺铂(16mg/kg)诱导小鼠肾损伤。将瑞士白化小鼠分为正常对照组、顺铂模型对照组、艾氏天芥菜的甲醇提取物治疗组(200和400mg/kg),并给予相应药物。于顺铂注射前4d开始每天予两组治疗组小鼠分别口服艾氏天芥菜的甲醇提取物200及400mg/kg,共服用7d。治疗结束后3d处死小鼠,并取血及肾脏组织,检测分析血尿素氮、血清肌酐和丙二醛水平以及过氧化氢酶和过氧化物歧化酶活性。结果:艾氏天芥菜的甲醇提取物能够显著降低因注射顺铂而引起的小鼠血尿素氮及血清肌酐升高(P<0.05),并且能降低顺铂引起的高丙二醛水平,同时升高降低的过氧化氢酶和过氧化物歧化酶活性(P<0.05)。此外,组织病理学检测显示艾氏天芥菜的甲醇提取物能够明显改善顺铂导致的肾小管坏死。结论:艾氏天芥菜的甲醇提取物可用于缓解顺铂的肾毒性。 | Surendra Kr.Sharma Naveen Goyal | 2012 | 中西医结合学报2012，10，5： | 6 |
| 10 | Magnesium:pathophysiological mechanisms and potential therapeutic roles in intracerebral hemorrhage显示文摘Intracerebral hemorrhage(ICH) remains the second-most common form of stroke with high morbidity and mortality.ICH can be divided into two pathophysiological stages:an acute primary phase,including hematoma volume expansion,and a subacute secondary phase consisting of blood-brain barrier disruption and perihematomal edema expansion.To date,all major trials for ICH have targeted the primary phase with therapies designed to reduce hematoma expansion through blood pressure control,surgical evacuation,and hemostasis.However,none of these trials has resulted in improved clinical outcomes.Magnesium is a ubiquitous element that also plays roles in vasodilation,hemostasis,and blood-brain barrier preservation.Animal models have highlighted potential therapeutic roles for magnesium in neurological diseases specifically targeting these pathophysiological mechanisms.Retrospective studies have also demonstrated inverse associations between admission magnesium levels and hematoma volume,hematoma expansion,and clinical outcome in patients with ICH.These associations,coupled with the multifactorial role of magnesium that targets both primary and secondary phases of ICH,suggest that magnesium may be a viable target of study in future ICH studies. | Jason J.Chang Rocco Armonda Nitin Goyal Adam S.Arthur | 2019 | Neural Regeneration Research2019，14，7： | 6 |
| 11 | Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements显示文摘Primary liver cancers carry significant morbidity and mortality.Hepatocellular carcinoma(HCC)develops within the hepatic parenchyma and is the most common malignancy originating from the liver.Although 80%of HCCs develop within background cirrhosis,20%may arise in a non-cirrhotic milieu and are referred to non-cirrhotic-HCC(NCHCC).NCHCC is often diagnosed late due to lack of surveillance.In addition,the rising prevalence of non-alcoholic fatty liver disease and diabetes mellitus have increased the risk of developing HCC on noncirrhotic patients.Viral infections such as chronic Hepatitis B and less often chronic hepatitis C with advance fibrosis are associated with NCHCC.NCHCC individuals may have Hepatitis B core antibodies and occult HBV infection,signifying the role of Hepatitis B infection in NCHCC.Given the effectiveness of current antiviral therapies,surgical techniques and locoregional treatment options,nowadays such patients have more options and potential for cure.However,these lesions need early identification with diagnostic models and multiple surveillance strategies to improve overall outcomes.Better understanding of the NCHCC risk factors,tumorigenesis,diagnostic tools and treatment options are critical to improving prognosis and overall outcomes on these patients.In this review,we aim to discuss NCHCC epidemiology,risk factors,and pathogenesis,and elaborate on NCHCC diagnosis and treatment strategies. | Abhilash Perisetti Hemant Goyal Rachana Yendala Ragesh B Thandassery Emmanouil Giorgakis | 2021 | World Journal of Gastroenterology2021，27，24： | 6 |
| 12 | Repetitive Sequences in Plant Nuclear DNA:Types, Distribution, Evolution and Function显示文摘Repetitive DNA sequences are a major component of eukaryotic genomes and may account for up to 90% of the genome size. They can be divided into minisatellite, microsatellite and satellite sequences. Satellite DNA sequences are considered to be a fast-evolving component of eukaryotic genomes, comprising tandemly-arrayed, highly-repetitive and highly-conserved monomer sequences. The monomer unit of satellite DNA is 150–400 base pairs(bp) in length.Repetitive sequences may be species- or genus-specific, and may be centromeric or subtelomeric in nature. They exhibit cohesive and concerted evolution caused by molecular drive, leading to high sequence homogeneity. Repetitive sequences accumulate variations in sequence and copy number during evolution, hence they are important tools for taxonomic and phylogenetic studies, and are known as ‘‘tuning knobs' ' in the evolution. Therefore, knowledge of repetitive sequences assists our understanding of the organization, evolution and behavior of eukaryotic genomes. Repetitive sequences have cytoplasmic, cellular and developmental effects and play a role in chromosomal recombination. In the post-genomics era, with the introduction of next-generation sequencing technology, it is possible to evaluate complex genomes for analyzing repetitive sequences and deciphering the yet unknown functional potential of repetitive sequences. | Shweta Mehrotra Vinod Goyal | 2014 | Genomics, Proteomics & Bioinformatics2014，12，4： | 5 |
| 13 | Ipsilateral fracture dislocations of the hip and knee joints with contralateral open fracture of the leg: a rare case and its management principles显示文摘这份报纸讨论了损害机制和有的伴随物 ipsilateral 臀部和膝脱臼和 contralateral 打开腿骨折的一个病人的管理。一个 32 岁的人与左臀部(小瓦锅的类型 IV ) 和关节和 contralateral 张开的膝(穆尔二世) 的 ipsilateral 破裂脱臼介绍了在一个汽车事故以后的腿骨头的骨折。在紧急情况以后使复生的措施,新潮的关节被减少,小瓦锅的破裂用 Ganz 途径被修理与落后螺丝钉;膝关节仔细被减少,胫骨的高原骨折与跨越 fixator 的侧面的撑墙板和 transarticular 被稳定。另外的腿上的开的破裂与外部 fixator 被清除并且修理。当他在麻醉下面被检查时,在在固定以后的两个关节没有不稳定性。破裂在 3 个月以后联合起来,病人没有臀部和膝的剩余不稳定性。没有在在 6 个月以后的新潮的关节的 osteonecrosis 的临床或放射学的证据。在一个年后续,他在两个关节与运动的几乎正常范围有令人满意的功能的结果。Ipsilateral 臀部和膝脱臼是稀罕损害,更多的小心为早诊断被需要。及时适当干预能处于这种状况提供好功能的结果给病人。 | Ramesh Kumar Sen Sujit Kumar Tripathy Vibhu Krishnan Tarun Goyal Vanyambadi Jagadeesh | 2011 | Chinese Journal of Traumatology2011，14，3： | 5 |
| 14 | All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's. | Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，7： | 5 |
| 15 | Impact of gout on in-hospital outcomes of acute coronary syndrome-related hospitalizations and revascularizations: Insights from the national inpatient sample显示文摘BACKGROUND Previous studies have established a role of gout in predicting risk and prognosis of cardiovascular diseases. However, large-scale data on the impact of gout on inpatient outcomes of acute coronary syndrome (ACS)-related hospitalizations and post-revascularization is inadequate. AIM To evaluate the impact of gout on in-hospital outcomes of ACS hospitalizations, subsequent healthcare burden and predictors of post-revascularization inpatient mortality. METHODS We used the national inpatient sample (2010-2014) to identify the ACS and goutrelated hospitalizations, relevant comorbidities, revascularization and postrevascularization outcomes using the ICD-9 CM codes. A multivariable analysis was performed to evaluate the predictors of post-revascularization in-hospital mortality. RESULTS We identified 3144744 ACS-related hospitalizations, of which 105198 (3.35%) also had gout. The ACS-gout cohort were more often older white males with a higher prevalence of comorbidities. Coronary artery bypass grafting was required more often in the ACS-gout cohort. Post-revascularization complications including cardiac (3.2% vs 2.9%), respiratory (3.5% vs 2.9%), and hemorrhage (3.1% vs 2.7%) were higher whereas all-cause mortality was lower (2.2% vs 3.0%) in the ACSgout cohort (P < 0.001). An older age (OR 15.63, CI: 5.51-44.39), non-elective admissions (OR 2.00, CI: 1.44-2.79), lower household income (OR 1.44, CI: 1.17- 1.78), and comorbid conditions predicted higher mortality in ACS-gout cohort undergoing revascularization (P < 0.001). Odds of post-revascularization inhospital mortality were lower in Hispanics (OR 0.45, CI: 0.31-0.67) and Asians (OR 0.65, CI: 0.45-0.94) as compared to white (P < 0.001). However, postoperative complications significantly raised mortality odds. Mean length of stay, transfer to other facilities, and hospital charges were higher in the ACS-gout cohort. CONCLUSION Although gout was not independently associated with an increased risk of postrevascularization in-hospital mortality in ACS, it did increase postrevascularization complications. | Rupak Desai Tarang Parekh Hemant Goyal Hee Kong Fong Dipen Zalavadia Nanush Damarlapally Rajkumar Doshi Sejal Savani Gautam Kumar Rajesh Sachdeva | 2019 | World Journal of Cardiology2019，11，5： | 4 |
| 16 | Endoscopic ultrasound-guided vascular interventions: Current insights and emerging techniques显示文摘Endoscopic ultrasound(EUS)is one of the significant breakthroughs in the field of advanced endoscopy.In the last two decades,EUS has evolved from a diagnostic tool to a real-time therapeutic modality.The luminal gastrointestinal(GI)tract provides a unique opportunity to access multiple vascular structures,especially in the mediastinum and abdomen,thus permitting a variety of EUS-guided vascular interventions.The addition of the doppler and contrast-enhanced capability to EUS has further helped provide real-time visualization of blood flow in vessels through the GI tract.EUS-guided vascular interventions rely on standard endoscopic accessories and interventional tools such as fine-needle aspiration needles and fine-needle biopsy.EUS allows the visualization of various structures in real-time by differentiating tissue densities and vascularity,thus,avoiding radiation exposure.EUS-guided techniques also allow real-time microscopic examination after target biopsy.Furthermore,many necessary interventions can be done during the same procedure after diagnosis.This article provides an overview of EUS-guided vascular interventions such as variceal,non-variceal bleeding interventions,EUSguided portal vein(PV)access with the formation of an intrahepatic portosystemic shunt,and techniques related to diagnosis of GI malignancies.Furthermore,we discuss current insights and future outlook of therapeutic modalities like PV embolization,PV sampling,angiography,drug administration,and portal pressure measurement. | Rupinder Mann Hemant Goyal Abhilash Perisetti Saurabh Chandan Sumant Inamdar Benjamin Tharian | 2021 | World Journal of Gastroenterology2021，27，40： | 4 |
| 17 | 经番木瓜种子甲醇分馏物长期治疗后大鼠的精子特点和睾丸超微结构显示文摘番木瓜种子的短期避孕效果已经确认,本文旨在研究大鼠长期服用番木瓜种子甲醇分馏物避孕的安全性和避孕机制。连续360天每天给雄性大鼠(n=40)口服番木瓜种子甲醇分馏物50mg kg^-1;对照组大鼠(n=40)给予橄榄油作为赋形剂。停止给药后120天对大鼠恢复情况进行测定。测量精子参数、血清睾酮水平、生育率、睾丸组织学及超微结构、血液学及血清临床化学,以评价番木瓜种子甲醇分馏物的安全性和有效性。大鼠健康状况、器官重量、血液学和临床化学均未改变,体重增加,证明了该长期治疗的安全性。Sertoli细胞中细胞核和细胞质体积减小、细胞核特征正常、胞质器中空泡形成,精母细胞和精子细胞核变性显示出生精受到干扰,这些均说明其避孕机制。Leydig细胞正常。治疗第60天在Sertoli细胞中观察到初始效果,治疗120—240天后精母细胞和精子细胞开始受影响。治疗60天后精子总数和精子存活率显著降低,精子活力完全抑制,精子异常增加,血清睾酮水平正常,不育率达到100%。停止治疗120天后,包括生育率在内的所有发生改变的参数都恢复到对照水平。本研究表明用番木瓜种子甲醇分馏物长期治疗是安全的,其避孕机制是通过对睾丸中精子细胞分化产生影响,可能由Sertoli细胞因素调节。 | Boomi Manivannan Ruchi Mittal Shipra Goyal Abdul S. Ansari Nirmal K. Lohiya | 2009 | Asian Journal of Andrology2009，11，5： | 4 |
| 18 | 环锭纺和紧密纺纱线的比较研究显示文摘比较研究了以棉、聚酯纤维为原料、在不同的紧密纺系统上纺制的相应的环锭纺和紧密纺纱线。结果表明紧密纺纱线与环锭纺纱线相比.弹性、拉伸性、耐磨性、刚度和紧密度较高,毛羽、条干不匀率和疵点较少,纱线直径较小。而且,紧密纺的弹性恢复参数比环锭纺要好得多。从改变比例的方面来说,RoCoS系统纺出来的纱线与Zinser和Suessen紧密纺系统纺出来的纱线相比较时,表现出弹性、直径和紧密度的改变量小,但是拉伸性变化大。 | A. Goyal P. Mishra A. Chutani | 2007 | 国际纺织导报2007，35，7： | 4 |
| 19 | JAMA:急性缺血性卒中血管内治疗的时间窗为7.3?h显示文摘2015年发表在NEJM上的5项大动脉闭塞急性缺血性卒中血管内治疗的随机试验证实第二代血管内再通治疗装置(主要是支架取栓装置)优于单独内科治疗。但是目前尚不清楚症状超过6 h患者血管内治疗的风险和获益,同样也不清楚发病6 h内获益的程度和时间之间的关系。美国、欧洲和加拿大国家指南推荐血管内治疗的时间窗为6 h,但是美国食品和药品管理局推荐时间窗为8 h,加拿大指南补充认为时间窗可达12 h。 | 杨中华 Saver JL Goyal M van der Lugt A | 2017 | 中国卒中杂志2017，12，1： | 4 |
| 20 | Statins Are Associated With a Reduced Risk of Hepatocellular Cancer: A Systematic Review and Meta-analysis显示文摘 | Siddharth Singh Preet Paul Singh Abha Goyal Singh Mohammad Hassan Murad William Sanchez | 2013 | Gastroenterology2013，，： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员