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| 1 | Differentiating Crohn's disease from intestinal tuberculosis显示文摘Differentiating Crohn's disease(CD) and intestinal tuberculosis(ITB) has remained a dilemma for most of the clinicians in the developing world, which are endemic for ITB, and where the disease burden of inflammatory bowel disease is on the rise. Although, there are certain clinical(diarrhea/hematochezia/perianal disease common in CD; fever/night sweats common in ITB), endoscopic(longitudinal/aphthous ulcers common in CD; transverse ulcers/patulous ileocaecal valve common in ITB), histologic(caseating/confluent/large granuloma common in ITB; microgranuloma common in CD), microbiologic(positive stain/culture for acid fast-bacillus in ITB), radiologic(long segment involvement/comb sign/skip lesions common in CD; necrotic lymph node/contiguous ileocaecal involvement common in ITB), and serologic differences between CD and ITB, the only exclusive features are caseation necrosis on biopsy, positive smear for acid-fast bacillus(AFB) and/or AFB culture, and necrotic lymph node on cross-sectional imaging in ITB. However,these exclusive features are limited by poor sensitivity, and this has led to the development of multiple multi-parametric predictive models. These models are also limited by complex formulae, small sample size and lack of validation across other populations. Several new parameters have come up including the latest Bayesian meta-analysis, enumeration of peripheral blood T-regulatory cells, and updated computed tomography based predictive score. However, therapeutic anti-tubercular therapy(ATT) trial, and subsequent clinical and endoscopic response to ATT is still required in a significant proportion of patients to establish the diagnosis. Therapeutic ATT trial is associated with a delay in the diagnosis of CD, and there is a need for better modalities for improved differentiation and reduction in the need for ATT trial. | Saurabh Kedia Prasenjit Das Kumble Seetharama Madhusudhan Siddhartha Dattagupta Raju Sharma Peush Sahni Govind Makharia Vineet Ahuja | 2019 | World Journal of Gastroenterology2019，25，4： | 19 |
| 2 | Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid:equilibrium binding studies on the interaction of daunomycin with deoxyribonucleic acid显示文摘 | CHAIRES J B DATTAGUPTA N CROTHERS D M | | 0，，： | 1 |
| 3 | Liver and portal histopathological correlation with age and survival in extra hepatic biliary atresia显示文摘 | Sharma S Das P Dattagupta S | | 0，，5： | 1 |
| 4 | Efficacy and tolerability of rifampicin based rescue therapy for Helicobacter pylori eradication failure in peptic ulcer disease显示文摘 | Ahuja V Bhatia V Dattagupta S | 2005 | Dig Dis Sci2005，50，4： | 1 |
| 5 | Clinical significance of altered expression of 显示文摘 | Kaur J Sawhney M Dattagupta S | 2013 | PLoS One2013，8，6： | 1 |
| 6 | Studies on interaction of anthracyeline antibiotics and deoxyribonucleic acid: equilibrium binding studies on the interaction of daunomycin with deoxyribonucleic acid显示文摘 | CHAIRES J B DATTAGUPTA N CROTHERS D M | 1982 | Biochemistry1982，21，： | 1 |
| 7 | A thermostable cysteine protease precursor from a tropical plant contains an unusual C-terminal propeptide: cDNA cloning, sequence comparison and molecular modeling studies显示文摘 | GHOSH R DATTAGUPTA J K BISWAS S | 2007 | Biochem Biophys Res Commun2007，362，4： | 1 |
| 8 | Synthesis and properties of acrylamide-substituted base pair specific dyes for deoxyribonucleic acid template mediated synthesis of dye polymers 显示文摘 | Buenemann H Dattagupta N Schuetz H J | 1981 | Biochemistry1981，20，： | 1 |
| 9 | Liver and portal histopathological correlation with age and survival in extra hepatic biliary atresia显示文摘 | Sharma S Das P Dattagupta S | | 0，，05： | 1 |
| 10 | Heterologous expression of a thermostable plant cysteine protease in Escherichia coli both in soluble and insoluble forms显示文摘 | DUTTA S GHOSH R DATTAGUPTA J K | 2010 | Process Biochem2010，45，8： | 1 |
| 11 | Niche differentiation among sulfur-oxidizing bac- terial populations in cave waters 显示文摘 | MACALADY J L DATTAGUPTA S SCHAPERDOTH I | 2008 | The ISME Jour- nal2008，2，6： | 1 |
| 12 | Fuzzy clustering with bi- ological knowledge for gene selection显示文摘 | Ghosh S Mitra S Dattagupta R | 2014 | Applied Soft Computing2014，16，1： | 1 |
| 13 | Liver and portal histopathological correlation with age and survival in extra hepatic biliary atresia显示文摘 | Sharma S Das P Dattagupta S | 2011 | Pediatr Surg Int2011，27，45： | 1 |
| 14 | A novel symbiosis between chemoautotrophic bacteria and a freshwater cave amphipod显示文摘 | Dattagupta S Schaperdoth I Montanari A | 2009 | International Society for Microbial Ecology2009，3，8： | 1 |
| 15 | Expression of recombinant hu- man catbepsin K is enhanced by codon optimization显示文摘 | Roy S Dattagupta J K Biswas S | 2012 | Process Bi- ochemistry2012，47，12： | 1 |
| 16 | Epigenetic alterations of CDH1 and APC genes: Relationship with activation of Wnt/β-catenin Pathway in invasive ductal carcinoma of breast显示文摘 | Chandra P. Prasad Sameer Mirza Gayatri Sharma Rajinder Prashad Siddhartha DattaGupta Gayatri Rath Ranju Ralhan | 2008 | Life Sciences2008，，9： | 1 |
| 17 | Liver and portal histopathological correlation with age and survival in extra hepatic biliary atresia显示文摘 | Sharma S Das P Dattagupta S | | 0，，05： | 1 |
| 18 | Studies on interaction of anthracycline antibiotics and deoxyribonudeic acid: equilibrium binding studies on the interaction of daunomycin with deoxyribonucleic acid 显示文摘 | Chaires J B Dattagupta N Crothers D M | 1982 | Biochemistry( S0916-8451 )1982，21，： | 1 |
| 19 | Vaginai angiomyofibroblastoma显示文摘 | Banerjee K DattaGupta S Mathur S R | 2004 | Arch Gynecol Obstet2004，270，2： | 1 |
| 20 | Liver and portal histopathological correlation with age and survival in extra hepatic biliary atresia显示文摘 | Sharma S Das P Dattagupta S | 2011 | Pediatric Surg Int2011，27，5： | 1 |
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