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| 1 | Ammonia-oxidizing archaea and bacteria are structured by geography in biological soil crusts across North American arid lands显示文摘Introduction:Biological soil crusts(BSCs)can dominate surface cover in dry lands worldwide,playing an integral role in arid land biogeochemistry,particularly in N fertilization through fixation and cycling.Nitrification is a characteristic and universal N transformation in BSCs that becomes important for the export of N beyond the microscopic bounds of the crust itself.The contribution of ammonia-oxidizing bacteria(AOB)in BSCs has been shown,but the role and extent of the recently discovered ammonia-oxidizing archaea(AOA)have not.Methods:We sampled various types of crusts in four desert regions across the western United States and characterized the composition and size of ammonia-oxidizing communities using clone libraries and quantitative PCR targeting the amoA gene,which codes for the ammonia monooxygenase enzyme,universally present in ammonia-oxidizing microbes.Results:All archaeal amoA sequences retrieved from BSCs belonged to the Thaumarchaeota(Nitrososphaera associated Group I.1b).Sequences from the Sonoran Desert,Colorado Plateau,and Great Basin were indistinguishable from each other but distinct from those of the Chihuahuan Desert.Based on amoA gene abundances,archaeal and bacterial ammonia oxidizers were ubiquitous in our survey,but the ratios of archaeal to bacterial ammonia oxidizers shifted from bacterially dominated in northern,cooler deserts to archaeally dominated in southern,warmer deserts.Conclusions:Archaea are shown to be potentially important biogeochemical agents of biological soil crust N cycling.Conditions associated with different types of BSCs and biogeographical factors reveal a niche differentiation between AOA and AOB,possibly driven by temperature. | Yevgeniy Marusenko Scott T Bates Ian Anderson Shannon L Johnson Tanya Soule Ferran Garcia-Pichel | 2013 | Ecological Processes2013，2，1： | 4 |
| 2 | p16/Ki-67在ASCUS合并HPV阳性患者中对宫颈高级别鳞状上皮内病变的检测意义显示文摘目的:探讨p16/Ki-67双染检测在不能明确意义的非典型鳞状上皮细胞(atypical squamous cell of undetermined significance/high risk human papillomavirus,ASCUS)合并高危型人乳头瘤病毒(human papillomavirus,HPV)阳性者中对宫颈高级别鳞状上皮内病变(high-grade squamous intraepithelial lesion,HSIL)的诊断价值。方法:回顾性分析2017年9月-2018年12月在南京医科大学第一附属医院妇科就诊的283例ASCUS合并高危型HPV阳性者阴道镜下的宫颈活检组织病理结果,探讨HSIL的危险因素,比较p16/Ki-67双染检测和HPV分型检测的诊断效能。结果:283例患者中88例被诊断为HSIL。单因素分析显示,不同HPV型别、p16/Ki-67双染检测结果间HSIL发生率差异有统计学意义(P<0.01),不同年龄患者HSIL发生率的差异无统计学意义(P>0.05)。多因素Logistic回归分析显示,HPV16/18阳性、p16/Ki-67双染检测阳性是HSIL的高危因素(P<0.001)。p16/Ki-67双染检测较HPV分型检测有更高的灵敏度(62.03%vs. 51.14%)、阴性预测值(81.6%vs. 78.9%)及受试者工作特征(ROC)曲线下面积(0.794 vs. 0.669,P<0.05)。结论:p16/Ki-67双染检测阳性是ASCUS合并HPV阳性者中发现HSIL的预警因素,其筛查效能优于HPV分型检测,为宫颈病变初筛提供了一种新选择。 | 方钦 Soule Hassanati 房园园 戎荣 邢燕 | 2019 | 南京医科大学学报(自然科学版)2019，39，10： | 4 |
| 3 | Molecular Characterization of the Calvin Cycle Enzyme Phosphoribulokinase in the Stramenopile Alga Vaucheria litorea and the Plastid Hosting Mollusc Elysia chlorotica显示文摘Phosphoribulokinase (PRK ) ,一个原子编码对光合的碳减小(加尔文) 唯一的质体局部性的酶周期,从 stramenopile 水藻 Vaucheria litorea 被克隆并且描绘。这水藻是为软体动物(海蛞蝓) 的质体的来源使动物能完全由 photoautotrophic CO2 幸存月的 Elysia chlorotica 固定。1633-bp V。litorea prk 基因被克隆并且编码区域,发现被四 introns 打断,编码 405-amino 酸蛋白质。这蛋白质包含被指导到建筑群的原子编码蛋白质期望的典型由两部组成的目标顺序(即四膜界限) 海藻的质体。PRK 和酶活动的 De novo 合成在 E 被检测。尽管有 V 被饿了的 chlorotica。为几个月的 litorea。不同于海藻的酶,在海蛞蝓的 PRK 没展出氧化还原作用规定。部分编码 PRK 基因的二个拷贝用 PCR 从两海蛞蝓和 aposymbiotic 海蛞蝓鸡蛋 DNA 被孤立。每个拷贝包含跨越 exon 的核苷酸区域 1 并且 exon 的部分 2 V。litorea prk,包括由两部组成的指向肽。然而,更大的 prk 碎片也包括 intron 1。在 E 的 prk 的 exon 和 intron 序列。chlorotica 和 V。litorea 是将近相同的。这些数据建议 PRK 是在 V 调整的差别。litorea 和 E。chlorotica 和 V 的至少部分。litorea 原子 PRK 基因在被饿几个月了的海蛞蝓是在场的。 | Mary E. Rumpho Sirisha Pochareddy Jared M. Worful Elizabeth J. Summer Debashish Bhattacharya Karen N. Pelletreau Mary S. Tyler Jungho Lee James R. Manhart Kara M. Soule | 2009 | Molecular Plant2009，2，6： | 3 |
| 4 | 互联网+供应链金融下应收账款融资模式显示文摘中国为了解决中小企业融资难和融资贵的难题,提出了供应链金融模式,该模式以供应链上核心企业的信用为基础,把贷款业务拓展与核心企业交易的上下游中小企业,能够有效地解决中小企业的资金问题并改善整个供应链的效率。本文对基于互联网的供应链金融下三种应收账款融资模式并结合实际案例,分析了具体的业务流程。最后,提出互联网供应链金融下应收账款质押融资、保理融资、资产证券化在中国进一步发展的建议。 | BAEK SOUL | 2018 | 时代金融2018，，20： | 2 |
| 5 | Silymarin Ascending Multiple Oral Dosing Phase I Study in Noncirrhotic Patients With Chronic Hepatitis C显示文摘 | Roy L. Hawke Sarah J. Schrieber Tedi A. Soule Zhiming Wen Philip C. Smith Rajender K. Reddy Abdus S. Wahed Steven H. Belle Nezam H. Afdhal Victor J. Navarro Josh Berman Qi-Ying Liu Edward Doo Michael W. Fried | 2010 | Journal of Clinical Pharmacology2010，，4： | 2 |
| 6 | A Randomized, Double-Blind, Controlled Withdrawal Trial in Crohn’s Disease Patients in Long-term Remission on Azathioprine显示文摘 | Marc Lémann Jean-Yves Mary Jean-Frédéric Colombel Bernard Duclos Jean-Claude Soule Eric Lerebours Robert Modigliani Yoram Bouhnik | 2005 | Gastroenterology2005，，7： | 2 |
| 7 | Who is at risk in the French mountains? Profiles of the accident victims in outdoor sports and mountain recreation显示文摘The risk of both severe and frequent injury associated with active pursuits in mountain areas is acknowledged. This phenomenon is all the most relevant to investigate in France that there is a growing enthusiasm for outdoor sports and recreation. This paper focuses on the social-demographic and sporting profiles of accident victims. Our intent is to better understand who is specifically at risk, while practicing mountain recreation, in the French mountains. Such identification doubtlessly constitutes an important asset in order to enhance prevention. Three critical activities are notably tackled, among some others: hiking, a widespread activity that exposes many practitioners to hazardous settings; mountaineering and ski touring, supposedly entailing the most severe injuries.In order to align the information collected, then provide estimations based on the reasoned crossing of these secondary data, we consulted and summarised all the databases that we knew of on the French territory: rescue team intervention reports, aggregated statistics from the sports ministry, sporting federation accident declarations, avalanche experts statistics, mountain guides union accident/incident reports, healthcare facilities admissions, etc. Only the sources consideredto be the most reliable and representative were used, owing to the number of cases processed, the exhaustive nature of data collection, or the level of information detail available. Our method also included consultation of all the parties playing an active role in prevention, training and mountain rescue, thus ensuring a participative, co-constructive approach to the study with the people that have the best knowledge of victim profiles. Around fifty such parties were interviewed on the methods implemented, the benefits and limits of current data, and the main expectations in terms of accidentology progress, thus further enhancing the credibility of the study proposed in this paper. Our results show that the parent population profiles(in terms of age, gender, place of residence, etc.), weighted by the level of exposure(frequency of participation, level of engagement, etc.) appears to have an impact on the accident victim profiles. There is certainly a very marked gender bias and a serious age impact to be taken into account, as well as the influence of the level of experience, which counter certain preconceived ideas and which, at the very least, go against instinct. However, aside from a probable over-exposure of experienced or expert participants, much remains to be explained concerning the accident mechanisms and circumstances involved. At this stage, we regret the analytic deficiencies induced by a lack ofknowledge concerning the parent populations in many cases, which makes interpretation difficult. | SOULE Bastien REYNIER Véronique LEFEVRE Brice BOUTROY Eric | 2017 | Journal of Mountain Science2017，14，8： | 2 |
| 8 | Intrarectal Amifostine During External Beam Radiation Therapy for Prostate Cancer Produces Significant Improvements in Quality of Life Measured by EPIC Score显示文摘 | Nicole L. Simone Cynthia Ménard Benjamin P. Soule Paul S. Albert Peter Guion Sharon Smith Denise Godette Nancy S. Crouse Linda C. Sciuto Theresa Cooley-Zgela Kevin Camphausen C. Norman Coleman Anurag K. Singh | 2008 | International Journal of Radiation Oncology, Biology, Physics2008，，1： | 2 |
| 9 | The keystone species concept in ecology and conservation显示文摘 | MILLS L S SOULE M E DOAK D F | 1993 | Biol Science1993，43，2： | 1 |
| 10 | Gene expression patterns associated with the biosynthesis of the sunscreen seytonemin in Nostoc punctiforrne ATCC 29133 in response to UVA Radiation显示文摘 | Soule Tanya Garcia Pichel Ferran Stout Valerie | 2009 | Bacteriology2009，191，14： | 1 |
| 11 | Cytomegalovirus accelerates chronic allograft nephropathy in a rat renal transplant model with associated provocative chemokine profiles 显示文摘 | Soule JL Streblow DN Andoh TF | 2006 | Transplant Proc2006，38，10： | 1 |
| 12 | Exploring internet addiction:demographic characteristics and stereotypes of heavy internet users显示文摘 | Lori C Soul L Wayne Shell Betty A Kleen | 2003 | The Journal of Computer Information System2003，，3： | 1 |
| 13 | Pathologic featuresof extraosseous Ewing’s sarcoma:a report from the IntergroupRhabdomyosarcoma Study显示文摘 | Shimada H Newton WA Jr Soule EH | 1988 | Hum Pathol1988，19，4： | 1 |
| 14 | Quantitative structure–activity relationship for 4-hydroxy-2-alkenal induced cytotoxicity in L6 muscle cells显示文摘 | Nicolas J. Pillon Laurent Soulère Roxane E. Vella Marine Croze Bertrand R. Caré Hedi A. Soula Alain Doutheau Michel Lagarde Christophe O. Soulage | 2010 | Chemico-Biological Interactions2010，，1： | 1 |
| 15 | Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery显示文摘 | Jane W. Newburger Richard A. Jonas Janet Soul Barry D. Kussman David C. Bellinger Peter C. Laussen Richard Robertson John E. Mayer Pedro J. del Nido Emile A. Bacha Joseph M. Forbess Frank Pigula Stephen J. Roth Karen J. Visconti Adre J. du Plessis David M | 2007 | The Journal of Thoracic and Cardiovascular Surger2007，，2： | 1 |
| 16 | Hydrocarbon-free resonance transition 795 nm rubidium laser显示文摘 | Wu S S Q Soules T F Page R H | 2007 | Opt Lett2007，32，16： | 1 |
| 17 | Eddy current offers a powerful tool for investigating residual stress and other metallurgical properties显示文摘 | Hong Chang Frederick C Schoenig Jr Jack A Soules | 1999 | Materials Evaluation1999，57，12： | 1 |
| 18 | What do genetics and ecology tell us about the design of nature reserve 显示文摘 | SOULE M E SIMBERLOFF D | 1986 | Biological Conservation1986，35，1： | 1 |
| 19 | Time course of changes in diffusion-weighted magnetic resonance imaging in a case of neonatal encephalopathy with defined onset and duration of hypoxic-ischemic insult显示文摘 | Robertson RL Tzika AA | 2001 | Pediatrics2001，108，： | 1 |
| 20 | Comparative study of some surface active properties of fi'uetoseesters and commecial sucrose esters显示文摘 | SOUL TANI S OGNIER S ENGASSER J M et el | 2003 | Colloids and Surfaces A: Physicochem Eng Aspects2003，227，： | 1 |
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