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| 1 | 高管晋升激励与财务重述——基于强度和概率的视角显示文摘利用2008-2013年中国上市公司的相关数据,采用混合样本、配对样本,研究了高管晋升激励对财务重述的影响。研究结果表明:高管晋升激励能够产生应有的激励效应,减少财务重述的发生;区分财务重述类型后,高管晋升激励对核心重述、非核心重述均能产生抑制作用;从CEO变更来看,发生CEO变更当年晋升激励对财务重述的抑制作用明显要比没有发生CEO变更的年份弱;从继任CEO的来源来看,继任CEO来自公司内部的高管晋升激励对财务重述的抑制作用明显要比继任CEO来自外部的公司强。 | 章琳一 张洪辉 Hedy Huang | 2016 | 山西财经大学学报2016，38，12： | 8 |
| 2 | Reciprocal crosstalk between dendritic cells and natural killer cells under the effects of PGE2 in immunity and immunopathology显示文摘在树枝状的房间(DC ) 和生来的杀手(NK ) 之间的相互的激活串音房间戏在对病毒和肿瘤调整有免疫力的防卫的一个枢轴的角色。生产 cytokine 能力, Th 房间极化能力和 chemokine 表达式,移植和 DC 的 stimulatory 函数被激活的 NK 房间调整。相反地,天生并且 NK 房间的受动器功能与激活的 DC 要求靠近的相互作用。包括 cytokines 和前列腺素(PG ) ,房间联系膜的分子和可溶的调停人贡献在 DC 和 NK 房间之间的双向串音。最著名、学习得好的 PG 之一是 PGE2。由许多房间类型生产了, PGE2 被显示了由对免疫系统的所有部件起作用影响有免疫力、煽动性的回答的各种各样的方面。正在出现 PGE2 在 DC 和 NK 房间生物学起关键作用的证据。几研究证明了 DC 是它在正常有免疫力的反应并且在有免疫力的混乱期间的 immunomodulatory 行动的 PGE2,而且一个目标的不仅来源。尽管 NK 房间看起来不能生产 PGE2,他们被描述为强大的反应 PGE2 房间,当他们表示所有 PGE2 E-prostanoid (EP ) 受体。几 NK 房间功能(细胞溶解,移植,增长, cytokine 生产) 被 PGE2 影响。这评论在正常和 immunopathological 过程在有免疫力的规定上在 DC-NK 房间串音和它的随后的影响上加亮 PGE2 的效果。 | Hedi Harizi | 2013 | Cellular & Molecular Immunology2013，10，3： | 7 |
| 3 | Pivotal Role of PGE_2 and IL-10 in the Cross-Regulation of Dendritic Cell-Derived Inflammatory Mediators显示文摘到病原体的暴露导致象巨噬细胞那样的介绍抗原的房间(APC ) 和树枝状的房间(DC ) 生产各种各样的内长的调停人,包括导出的 arachidonic 酸(AA ) eicosanoids, cytokines,和氮的氧化物(没有) 。激活的 APC 的许多分泌产品能以一种 autocrine 方式自己行动并且调制他们的功能。而且,在内长的 bioactive 分子之间跨相互作用为他们激活并且支撑有免疫力、煽动性的回答,并且调整有免疫力的动态平衡的能力与重要后果调整职业 APC 的函数。尽管为许多忽视了什么时候的年与他们在心血管的动态平衡,癌症和发炎的角色相比,在免疫学的 eicosanoids 的重要性正在变得更多定义。前列腺素(PG ) 的角色 E2 (PGE2 ) ,知道的最好和大多数之一很好学习了 eicosanoids,具有特别兴趣。它由对他们分泌 cytokines 的区别,成熟和他们的能力起作用调制职业 DC 的活动。特别地在造血的 cytokines 之中, interleukin-10 (IL-10 ) 是显示 immunostimulatory 和 immunoregulatory 活动的一个多种的分子。因为它的反煽动性的性质, IL-10 依附许多注意。它由 myeloid 起源的房间调制 cytokines,可溶的调停人和房间表面分子的表示,特别地巨噬细胞和 DC。我们以前报导 PGE2 是在骨头的 IL-10 的有势力 inducer 导出髓的 DC (BM-DC ) ,和导致 PGE2 的 IL-10 是 BM-DC 支持 inflammatory 显型的一个关键管理者。BM-DC 可以被看作一个重要模型学习在内长的调停人之间的复杂相互作用,并且 autocrine IL-10 在导出 AA 的类脂化合物调停人,的 crossregulation 起一个枢轴的作用 cytokines,并且没有,与有免疫力、煽动性的回答上的批评效果。细胞与分子的免疫学。2006; 3 (4 ): 271-277。 | Hedi Harizi Norbert Gualde | 2006 | Cellular & Molecular Immunology2006，3，4： | 6 |
| 4 | Regional Features and Seasonality of Land–Atmosphere Coupling over Eastern China显示文摘Land-atmosphere coupling is a key process of the climate system, and various coupling mechanisms have been proposed before based on observational and numerical analyses. The impact of soil moisture(SM) on evapotranspiration(ET) and further surface temperature(ST) is an important aspect of such coupling. Using ERA-Interim data and CLM4.0 offline simulation results, this study further explores the relationships between SM/ST and ET to better understand the complex nature of the land-atmosphere coupling(i.e., spatial and seasonal variations) in eastern China, a typical monsoon area. It is found that two diagnostics of land-atmosphere coupling(i.e., SM-ET correlation and ST-ET correlation) are highly dependent on the climatology of SM and ST. By combining the SM-ET and ST-ET relationships, two 'hot spots' of land-atmosphere coupling over eastern China are identified: Southwest China and North China. In Southwest China, ST is relatively high throughout the year, but SM is lowest in spring, resulting in a strong coupling in spring. However, in North China, SM is relatively low throughout the year, but ST is highest in summer, which leads to the strongest coupling in summer. Our results emphasize the dependence of land-atmosphere coupling on the seasonal evolution of climatic conditions and have implications for future studies related to land surface feedbacks. | Chujie GAO Haishan CHEN Shanlei SUN Bei XU Victor ONGOMA Siguang ZHU Hedi MA Xing LI | 2018 | Advances in Atmospheric Sciences2018，35，6： | 5 |
| 5 | A critical role of the thioredoxin domain containing protein 5(TXNDC5) in redox homeostasis and cancer development显示文摘Correct folding of nascent peptides occurs in the endoplasmic reticulum(ER).It is a complicate process primarily accomplished by the coordination of multiple redox proteins including members of the protein disulfide isomerase(PDI)family.As a critical member of the PDI family,thioredoxin domain containing protein 5(TXNDC5)assists the folding of newly synthesized peptides to their mature form through series of disulfide bond exchange reactions.Interestingly,TXNDC5 is frequently found overexpressed in specimens of many human diseases including various types of cancer.In this review,we summarized the biochemical function of TXNDC5 in mammalian cells and the recent progress on the understanding of its role and molecular mechanisms in cancer development.Findings of TXNDC5 in the activation of intracellular signaling pathways,stimulation of cell growth&proliferation,facilitation of cell survival and modulation of extracellular matrix to affect cancer cell invasion and metastasis are reviewed.These published studies suggest that strategies of targeting TXNDC5 can be developed as potentially valuable methods for the treatment of certain types of cancer in patients. | Hedy A.Chawsheen Qi Ying Hong Jiang Qiou Wei | 2018 | Genes & Diseases2018，5，4： | 4 |
| 6 | Borderline Resectable Pancreatic Cancer: Need for Standardization and Methods for Optimal Clinical Trial Design显示文摘 | Matthew H. G. Katz Robert Marsh Joseph M. Herman Qian Shi Eric Collison Alan P. Venook Hedy L. Kindler Steven R. Alberts Philip Philip Andrew M. Lowy Peter W. T. Pisters Mitchell C. Posner Jordan D. Berlin Syed A. Ahmad | 2013 | Annals of Surgical Oncology2013，，8： | 4 |
| 7 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011，，3： | 4 |
| 8 | Structural requirements and interaction mechanisms of ACE inhibitory peptides:molecular simulation and thermodynamics studies on LAPYK and its modifi ed peptides显示文摘The understanding of the structural requirements and the intermolecular-interaction mechanism are important for discovering potent angiotensin-converting enzyme(ACE)inhibitory peptides.In this study,we modifi ed an egg-white derived peptide,LAPYK,using the amino acids with different properties to produce the LAPYK-modified peptides.The ACE inhibitory activities of the modified peptides were determined to explore the structural requirements of ACE inhibitory peptides(ACEIPs).Molecular simulation and isothermal titration calorimetry analysis were used to investigate interactions between the peptides and ACE.We found that hydrophobicity and the amino acids with ring structures were benefi cial for the ACE inhibitory activities of the peptides.The results of the molecular mechanics poisson boltzmann surface area(MMPBSA)binding free energy calculations indicated that the polar solvation free energy(ΔG_(polar))of the charged peptides(LAPYK,LAPYE)were unfavorable for binding to ACE.On the other hand,the results of isothermal titration calorimetry analyses suggested that the enthalpy-driven ACE-peptide interactions were more favorable than the entropy-driven ACE-peptide interaction counterparts. | Biying Zhang Jingbo Liu Hedi Wen Feng Jiang Erlei Wang Ting Zhang | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 9 | Multiple pyogenic liver abscess显示文摘多重生脓肝脓肿很少被描述了。我们报导影响要求外科的排水的一个 38 岁的女人的多重生脓肝脓肿的一个致命的案例。进化被出现标记一腐败有多器官的吃惊系统失败。病人死了在外科以后的 48 h。疾病的原因,治疗学和结果被讨论。 | Mabrouk Bahloul Anis Chaari Nadia Bouaziz-Khlaf Hatem Kallel Leila Herguefi Hedi Chelly Chokri Ben Hamida Mounir Bouaziz | 2006 | World Journal of Gastroenterology2006，12，18： | 2 |
| 10 | Superselective embolisation of bilateral superior vesical arteries for management of intractable hematuria in context of metastatic bladder cancer显示文摘Hematuria due to locally advanced or metastatic bladder cancer is a common condition and is often a management problem.Percutaneous embolisation is a mini-invasive option to handle this situation.We report a case of a patient with a metastatic bladder cancer and who presented with an abundant hematuria and severe anemia.After failure of endoscopic resections and“flush”of radiotherapy haemostatic and refusal of cystectomy by the patient,he was treated by superselective embolisation of bilateral superior bladder arteries with excellent immediate results.The technique is safe and effective in the short term.The longterm effectiveness requires further investigation. | Ahmed Saadi Abderrazak Bouzouita Mohamed Hedi Rebai Mohamed Cherif Walid Kerkeni Haroun Ayed Amine Derouiche Hatem Rajhi Riadh Ben Slama Najla Mnif Mohamed Chebil | 2017 | Asian Journal of Urology2017，4，2： | 2 |
| 11 | Functional grouping and cortical–subcortical interactions in emotion: A meta-analysis of neuroimaging studies显示文摘 | Hedy Kober Lisa Feldman Barrett Josh Joseph Eliza Bliss-Moreau Kristen Lindquist Tor D. Wager | 2008 | Neuroimage2008，，2： | 2 |
| 12 | A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer显示文摘 | Ramesh K. Ramanathan Chandra P. Belani Deepti A. Singh Michael Tanaka Heinz-Josef Lenz Yun Yen Hedy L. Kindler Syma Iqbal Jeff Longmate Philip C. Mack Georg Lurje Regina Gandour-Edwards Janet Dancey David R. Gandara | 2009 | Cancer Chemotherapy and Pharmacology2009，，4： | 2 |
| 13 | Evaluating the photovoltaic properties of two conjugated polymers synthesized by Suzuki polycondensation and direct C–H activation显示文摘Two conjugated polymers HXS-1 and PDFCDTBT were prepared by direct C–H activation and Suzuki polycondensation and their chemical structures were characterized by 1H NMR spectroscopy.The molecular weight of conjugated polymer synthesized by direct C–H activation is lower than the corresponding polymers prepared by Suzuki polycondensation.Conjugated polymers synthesized by direct C–H activation have considerable solubility in common organic solvents and form amorphous film.The photovoltaic property of conjugated polymers synthesized by direct C–H activation is inferior to the corresponding polymers synthesized by Suzuki polycondensation. | Hedi Wei Heng Lu Tao Fang Zhishan Bo | 2015 | Science China Chemistry2015，58，2： | 2 |
| 14 | Guided Modes in Rectangular Waveguides Partially Filled with Single Negative Metamaterial Slab显示文摘 | Hedi Sakli Wyssem Fathallah Khaled Issa Taoufik Aguili | 2013 | 材料科学与工程(中英文A版)2013，3，3： | 2 |
| 15 | Growth in Cities显示文摘 | Glaeser E Hedi K Jose S Andrei S | 1992 | Journal of Political Economy1992，100，6： | 1 |
| 16 | Phase Ⅱ trial of bevacizumab plus gemcitabine in pantients with advanced pancreatic cancer显示文摘 | Kindler Hedy L Friberg Gregory Singh Deepti A | 2005 | J Clin Oncol2005，23，： | 1 |
| 17 | Effect of the Nature of Carbon Catalysts on Glyphosate Synthesis显示文摘 | CHATERINE P EMMANUEL L HEDI L et ol | 1999 | Journal of Catalyst1999，182，： | 1 |
| 18 | Nonlinear Stock Market Integration in Emerging Countries显示文摘 | Mohamed EI Hedi Fredj J | 2010 | Intemational Journal of Economics and Finance2010，2，05： | 1 |
| 19 | Quantitative structure–activity relationship for 4-hydroxy-2-alkenal induced cytotoxicity in L6 muscle cells显示文摘 | Nicolas J. Pillon Laurent Soulère Roxane E. Vella Marine Croze Bertrand R. Caré Hedi A. Soula Alain Doutheau Michel Lagarde Christophe O. Soulage | 2010 | Chemico-Biological Interactions2010，，1： | 1 |
| 20 | Improved survival with ipilimumab in patients with metastatic melanoma 显示文摘 | Hedi FS O'Day SI McDermott DF | 2010 | New Engl J Med2010，363，8： | 1 |
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